IT1283467B1 - Derivati di cicloalcani 1,2 sostituiti come inibitori della trombina, procedimento per la loro preparazione e loro impiego in formulazioni - Google Patents
Derivati di cicloalcani 1,2 sostituiti come inibitori della trombina, procedimento per la loro preparazione e loro impiego in formulazioniInfo
- Publication number
- IT1283467B1 IT1283467B1 IT96MI001512A ITMI961512A IT1283467B1 IT 1283467 B1 IT1283467 B1 IT 1283467B1 IT 96MI001512 A IT96MI001512 A IT 96MI001512A IT MI961512 A ITMI961512 A IT MI961512A IT 1283467 B1 IT1283467 B1 IT 1283467B1
- Authority
- IT
- Italy
- Prior art keywords
- formulations
- derivatives
- procedure
- preparation
- thrombin inhibitors
- Prior art date
Links
- 229940122388 Thrombin inhibitor Drugs 0.000 title 1
- 150000001924 cycloalkanes Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000003868 thrombin inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/10—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI001512A IT1283467B1 (it) | 1996-07-19 | 1996-07-19 | Derivati di cicloalcani 1,2 sostituiti come inibitori della trombina, procedimento per la loro preparazione e loro impiego in formulazioni |
| PCT/EP1997/003774 WO1998003540A2 (en) | 1996-07-19 | 1997-07-15 | 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations |
| AU35437/97A AU3543797A (en) | 1996-07-19 | 1997-07-15 | 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI001512A IT1283467B1 (it) | 1996-07-19 | 1996-07-19 | Derivati di cicloalcani 1,2 sostituiti come inibitori della trombina, procedimento per la loro preparazione e loro impiego in formulazioni |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI961512A0 ITMI961512A0 (it) | 1996-07-19 |
| ITMI961512A1 ITMI961512A1 (it) | 1998-01-19 |
| IT1283467B1 true IT1283467B1 (it) | 1998-04-21 |
Family
ID=11374623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT96MI001512A IT1283467B1 (it) | 1996-07-19 | 1996-07-19 | Derivati di cicloalcani 1,2 sostituiti come inibitori della trombina, procedimento per la loro preparazione e loro impiego in formulazioni |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU3543797A (it) |
| IT (1) | IT1283467B1 (it) |
| WO (1) | WO1998003540A2 (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999050230A1 (en) * | 1998-03-31 | 1999-10-07 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease |
| US6462076B2 (en) * | 2000-06-14 | 2002-10-08 | Hoffmann-La Roche Inc. | Beta-amino acid nitrile derivatives as cathepsin K inhibitors |
| US6759428B2 (en) | 2001-12-04 | 2004-07-06 | Roche Palo Alto Llc | Indole nitriles |
| DE60219068T2 (de) | 2001-12-04 | 2007-12-13 | F. Hoffmann-La Roche Ag | Substituierte 2-amino-cykloalkankarboxamide und ihre verwendung als cysteinprotease-inhibitoren |
| WO2005000793A1 (ja) * | 2003-06-26 | 2005-01-06 | Taisho Pharmaceutical Co., Ltd. | ２位置換シクロアルキルカルボン酸誘導体 |
| US9422314B2 (en) * | 2012-12-07 | 2016-08-23 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| CN114437119A (zh) * | 2020-10-30 | 2022-05-06 | 苏州开拓药业股份有限公司 | 一种c-Myc蛋白抑制剂及其制备方法和用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU184368B (en) * | 1981-01-13 | 1984-08-28 | Gyogyszerkutato Intezet | Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate |
| US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
-
1996
- 1996-07-19 IT IT96MI001512A patent/IT1283467B1/it active IP Right Grant
-
1997
- 1997-07-15 WO PCT/EP1997/003774 patent/WO1998003540A2/en active Application Filing
- 1997-07-15 AU AU35437/97A patent/AU3543797A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU3543797A (en) | 1998-02-10 |
| ITMI961512A1 (it) | 1998-01-19 |
| WO1998003540A3 (en) | 1998-04-09 |
| WO1998003540A2 (en) | 1998-01-29 |
| ITMI961512A0 (it) | 1996-07-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ITFI930247A1 (it) | Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche. | |
| ITMI950529A0 (it) | Composizioni farmaceutiche e procedimento per la loro preparazione | |
| ITMI991860A0 (it) | Derivati di acidi 2-ammino-biciclo(3.1.0)-esan-2,6-bicarbossilici e pr ocedimento per la loro preparazione | |
| HUP0102113A3 (en) | 2-(2,6-dioxopiperidin-3-yl)isoindoline derivatives, their preparation and their use as inhibitors of inflammatory cytokines | |
| EE05086B1 (et) | Primidiini derivaadid, nende valmistamismeetod ja kasutamine, farmatseutiline kompositsioon ja selle valmistamismeetod, kombinatsioon ning saadus | |
| EE9800459A (et) | Spiro-piperidiini derivaadid ja nende kasutamine terapeutiliste toimeainetena | |
| ITMI941635A0 (it) | Derivati metallorganici del grupo iiia e procedimento per la loro preparazione | |
| EE9800425A (et) | Uued aminohappe derivaadid ja nende kasutamine trombiini inhibiitoritena | |
| FI962908A (fi) | Mikrobinvastainen koostumus, sen valmistusmenetelmä ja sen käyttö | |
| EE9800339A (et) | Aminoisokinoliinid ja aminotienopüridiini derivaadid ning nende kasutamine põletikuvastaste ainetena | |
| IT1293968B1 (it) | Produzione ed utilizzo di composizioni comprendenti alte concentrazioni di attivita' di vitamina b12. | |
| NO20031622L (no) | Medisinske blandinger som raskt desintegrerer i munnhulen og fremgangsmåtefor fremstilling av samme | |
| IT1289581B1 (it) | Miscela,composizione per la protezione delle piante contenente la miscela e suo impiego | |
| EE03825B1 (et) | 2-tsüanoiminoimidasooli derivaadid, nende valmistamismeetod, kasutamine ja farmatseutilised kompositsioonid | |
| ITMI962462A0 (it) | Composizioni cosmetiche antisolari comprendenti derivati del dibenzoilmetano e del benzofenone | |
| ITRM940269A0 (it) | Derivati glutationici delle antracicline e procedimento per ottenerli. | |
| ITMI962406A0 (it) | Procedimento per la preparazione di derivati cefalosporanici | |
| HUP9904165A3 (en) | 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase and use thereof | |
| IT1283467B1 (it) | Derivati di cicloalcani 1,2 sostituiti come inibitori della trombina, procedimento per la loro preparazione e loro impiego in formulazioni | |
| ITMI910080A0 (it) | Nuovi derivati arilvinilamidici e procedimento per la loro preparazione | |
| IT1256623B (it) | Antagonisti delle tachichinine, procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche | |
| NO990913D0 (no) | Naftylforbindelser, intermediater, sammensetninger og metoder for anvendelse | |
| ITMI940989A0 (it) | Derivati di acidi ammino-solfonici , loro impiego nella sintesi di pseudopeptidi e procedimento per la loro preparazione | |
| ITRM960867A0 (it) | Impiego di 2 ciclopenten 1-one e suoi derivati come inibitori del fat tore nf-kb | |
| ITMI951417A0 (it) | Composizioni farmaceutiche e procedimento per la loro preparazione |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |