AU3543797A - 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations - Google Patents
1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulationsInfo
- Publication number
- AU3543797A AU3543797A AU35437/97A AU3543797A AU3543797A AU 3543797 A AU3543797 A AU 3543797A AU 35437/97 A AU35437/97 A AU 35437/97A AU 3543797 A AU3543797 A AU 3543797A AU 3543797 A AU3543797 A AU 3543797A
- Authority
- AU
- Australia
- Prior art keywords
- preparation
- pharmaceutical formulations
- substituted cycloalkane
- cycloalkane derivatives
- thrombine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000001924 cycloalkanes Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/10—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96MI001512A IT1283467B1 (en) | 1996-07-19 | 1996-07-19 | DERIVATIVES OF 1,2 SUBSTITUTED CYCLOALKANES AS THROMBIN INHIBITORS, PROCEDURE FOR THEIR PREPARATION AND THEIR USE IN FORMULATIONS |
ITMI96A1512 | 1996-07-19 | ||
PCT/EP1997/003774 WO1998003540A2 (en) | 1996-07-19 | 1997-07-15 | 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
AU3543797A true AU3543797A (en) | 1998-02-10 |
Family
ID=11374623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU35437/97A Abandoned AU3543797A (en) | 1996-07-19 | 1997-07-15 | 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU3543797A (en) |
IT (1) | IT1283467B1 (en) |
WO (1) | WO1998003540A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2281170T3 (en) * | 1998-03-31 | 2007-09-16 | Vertex Pharmaceuticals Incorporated | SERINA PROTEASES INHIBITORS, PARTICULARLY PROTEASE NS3 OF THE HEPATITIS VIRUS C. |
US6462076B2 (en) * | 2000-06-14 | 2002-10-08 | Hoffmann-La Roche Inc. | Beta-amino acid nitrile derivatives as cathepsin K inhibitors |
BR0214642A (en) | 2001-12-04 | 2004-11-03 | Hoffmann La Roche | Compounds, methods for preparing a compound, pharmaceutical compositions comprising the same and a method for treating and / or preventing diseases that are associated with cysteine proteas and use of such compounds. |
US6759428B2 (en) | 2001-12-04 | 2004-07-06 | Roche Palo Alto Llc | Indole nitriles |
WO2005000793A1 (en) * | 2003-06-26 | 2005-01-06 | Taisho Pharmaceutical Co., Ltd. | 2-substituted cycloalkylcarboxylic acid derivative |
US9422314B2 (en) * | 2012-12-07 | 2016-08-23 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
CN114437119B (en) * | 2020-10-30 | 2024-08-09 | 苏州开拓药业股份有限公司 | C-Myc protein inhibitor and preparation method and application thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU184368B (en) * | 1981-01-13 | 1984-08-28 | Gyogyszerkutato Intezet | Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate |
US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
-
1996
- 1996-07-19 IT IT96MI001512A patent/IT1283467B1/en active IP Right Grant
-
1997
- 1997-07-15 WO PCT/EP1997/003774 patent/WO1998003540A2/en active Application Filing
- 1997-07-15 AU AU35437/97A patent/AU3543797A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1998003540A2 (en) | 1998-01-29 |
WO1998003540A3 (en) | 1998-04-09 |
IT1283467B1 (en) | 1998-04-21 |
ITMI961512A0 (en) | 1996-07-19 |
ITMI961512A1 (en) | 1998-01-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU679663B2 (en) | Dermatological or pharmaceutical composition, preparation process and use | |
AU3265695A (en) | Novel naphthyridine derivative and medicinal composition thereof | |
AP9901556A0 (en) | Sulpponamide derivatives process for their preparation and their use as medicaments | |
HUP9900974A3 (en) | Heterocycle-condensed morphinoid derivatives, process for the preparation thereof, their use and pharmaceutical compositions containing them | |
HUP0203542A3 (en) | 3(5)-amino-pyrazole derivatives, process for their preparation, their use and pharmaceutical compositions containing the same | |
AU2505795A (en) | 1-arylpyrimidine derivatives and pharmaceutical use thereof | |
AU7640696A (en) | Thiazolidinedione derivatives, method for preparing the derivatives and pharmaceutical compositions containing same | |
IL111533A0 (en) | Quinoxalinedione derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same | |
IL148870A0 (en) | 2'-substituted 1, 1'-biphenyl-2-carbonamides, method for the production thereof, use thereof as medicament and pharmaceutical preparations containing said compounds | |
AU8627898A (en) | Pyrimidin-2,4,6-trion derivatives, method for producing the same and medicinal products containing these compounds | |
IL136425A0 (en) | Substituted thiazolidinedione derivative, process for its preparation and its pharmaceutical use | |
AU5565099A (en) | Pharmaceutical compositions and methods for use | |
HUP9901485A2 (en) | Heterocyclylcarboxamide derivatives, pharmaceutical compositions containing the same, process for their preparation and their use | |
AU3543797A (en) | 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations | |
AU3011095A (en) | 2,3-bridged 1,4-dihydropyridines, processes for their preparation and their use as medicaments | |
GB9310075D0 (en) | New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same | |
AU2001254812A1 (en) | 9-oxa-epothilon derivatives, method for the production and use thereof in pharmaceutical preparations | |
AU4062995A (en) | 1-oxo-2-(phenylsulphonylamino) pentylpiperidine derivatives, their preparation and their therapeutic application | |
AU4845196A (en) | 2-sulfinylnicotinamide derivatives, intermediate thereof, process for producing 2-sulfinylnicotinamide derivatives, and medicinal composition containing the same as active ingredient | |
AU1251295A (en) | Substituted benzimidazole, processes for its preparation and its pharmaceutical use | |
AU8379091A (en) | New amino acid derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same | |
AU685006B2 (en) | Metallocenic diarylethylene derivatives, methods for their preparation and pharmaceutical compositions containing same | |
AU2880699A (en) | Pharmaceutical compositions and methods for use | |
AU2930995A (en) | Silylmethyl-aniline derivatives, methods of preparation and use thereof as drugs | |
AU4264096A (en) | 3,4-dihydro-2,5,7,8-tetramethyl-benzopyran-6-ol derivatives for use as drugs |