AU3543797A - 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations - Google Patents

1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations

Info

Publication number
AU3543797A
AU3543797A AU35437/97A AU3543797A AU3543797A AU 3543797 A AU3543797 A AU 3543797A AU 35437/97 A AU35437/97 A AU 35437/97A AU 3543797 A AU3543797 A AU 3543797A AU 3543797 A AU3543797 A AU 3543797A
Authority
AU
Australia
Prior art keywords
preparation
pharmaceutical formulations
substituted cycloalkane
cycloalkane derivatives
thrombine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU35437/97A
Inventor
Cristina Di Bugno
Raffaello Giorgi
Nicholas Harmat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Menarini Industrie Farmaceutiche Riunite SRL
Original Assignee
Menarini Industrie Farmaceutiche Riunite SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Industrie Farmaceutiche Riunite SRL filed Critical Menarini Industrie Farmaceutiche Riunite SRL
Publication of AU3543797A publication Critical patent/AU3543797A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/10—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU35437/97A 1996-07-19 1997-07-15 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations Abandoned AU3543797A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT96MI001512A IT1283467B1 (en) 1996-07-19 1996-07-19 DERIVATIVES OF 1,2 SUBSTITUTED CYCLOALKANES AS THROMBIN INHIBITORS, PROCEDURE FOR THEIR PREPARATION AND THEIR USE IN FORMULATIONS
ITMI96A1512 1996-07-19
PCT/EP1997/003774 WO1998003540A2 (en) 1996-07-19 1997-07-15 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations

Publications (1)

Publication Number Publication Date
AU3543797A true AU3543797A (en) 1998-02-10

Family

ID=11374623

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35437/97A Abandoned AU3543797A (en) 1996-07-19 1997-07-15 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations

Country Status (3)

Country Link
AU (1) AU3543797A (en)
IT (1) IT1283467B1 (en)
WO (1) WO1998003540A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3376699A (en) * 1998-03-31 1999-10-18 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
US6462076B2 (en) * 2000-06-14 2002-10-08 Hoffmann-La Roche Inc. Beta-amino acid nitrile derivatives as cathepsin K inhibitors
KR20050044660A (en) 2001-12-04 2005-05-12 에프. 호프만-라 로슈 아게 Substituted 2-amino-cycloalkanecarboxamides and their use as cysteine protease inhibitors
US6759428B2 (en) 2001-12-04 2004-07-06 Roche Palo Alto Llc Indole nitriles
WO2005000793A1 (en) * 2003-06-26 2005-01-06 Taisho Pharmaceutical Co., Ltd. 2-substituted cycloalkylcarboxylic acid derivative
PT2928898T (en) * 2012-12-07 2021-07-05 Venatorx Pharmaceuticals Inc Beta-lactamase inhibitors
CN114437119A (en) * 2020-10-30 2022-05-06 苏州开拓药业股份有限公司 C-Myc protein inhibitor and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184368B (en) * 1981-01-13 1984-08-28 Gyogyszerkutato Intezet Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate
US4499079A (en) * 1982-11-18 1985-02-12 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides

Also Published As

Publication number Publication date
ITMI961512A1 (en) 1998-01-19
IT1283467B1 (en) 1998-04-21
WO1998003540A3 (en) 1998-04-09
WO1998003540A2 (en) 1998-01-29
ITMI961512A0 (en) 1996-07-19

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