ITRM940269A0 - Derivati glutationici delle antracicline e procedimento per ottenerli. - Google Patents
Derivati glutationici delle antracicline e procedimento per ottenerli.Info
- Publication number
- ITRM940269A0 ITRM940269A0 ITRM940269A ITRM940269A ITRM940269A0 IT RM940269 A0 ITRM940269 A0 IT RM940269A0 IT RM940269 A ITRM940269 A IT RM940269A IT RM940269 A ITRM940269 A IT RM940269A IT RM940269 A0 ITRM940269 A0 IT RM940269A0
- Authority
- IT
- Italy
- Prior art keywords
- glutation
- anthracyclins
- derivatives
- procedure
- glutation derivatives
- Prior art date
Links
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical class OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM940269A IT1272234B (it) | 1994-05-02 | 1994-05-02 | Derivati glutationici delle antracicline e procedimento per ottenerli. |
US08/432,836 US5646177A (en) | 1994-05-02 | 1995-05-02 | Glutathione derivatives of anthracyclines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM940269A IT1272234B (it) | 1994-05-02 | 1994-05-02 | Derivati glutationici delle antracicline e procedimento per ottenerli. |
Publications (3)
Publication Number | Publication Date |
---|---|
ITRM940269A0 true ITRM940269A0 (it) | 1994-05-02 |
ITRM940269A1 ITRM940269A1 (it) | 1995-11-02 |
IT1272234B IT1272234B (it) | 1997-06-16 |
Family
ID=11402509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITRM940269A IT1272234B (it) | 1994-05-02 | 1994-05-02 | Derivati glutationici delle antracicline e procedimento per ottenerli. |
Country Status (2)
Country | Link |
---|---|
US (1) | US5646177A (it) |
IT (1) | IT1272234B (it) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR19990084528A (ko) * | 1998-05-07 | 1999-12-06 | 박상철 | 신규 안트라사이클린 유도체 및 제조방법 |
US6235782B1 (en) | 1998-11-12 | 2001-05-22 | Rifat Pamukcu | Method for treating a patient with neoplasia by treatment with a platinum coordination complex |
US6235776B1 (en) | 1998-11-12 | 2001-05-22 | Cell Pathways, Inc. | Method for treating a patient with neoplasia by treatment with a paclitaxel derivative |
GB0011059D0 (en) * | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
GB0015446D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
GB0015447D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
GB0016447D0 (en) * | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
GB0017852D0 (en) * | 2000-07-20 | 2000-09-06 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
IT1318696B1 (it) * | 2000-09-15 | 2003-08-27 | Pharmacia & Upjohn Spa | Coniugati di glutatione con derivati della distamicina ad attivita'antitumorale. |
GB0029004D0 (en) * | 2000-11-28 | 2001-01-10 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
US20070249651A1 (en) * | 2001-06-20 | 2007-10-25 | Nerviano Medical Sciences S.R.I. | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
US7172905B2 (en) * | 2001-08-07 | 2007-02-06 | The University Of Chicago | Polypeptide immobilization |
US6969592B2 (en) * | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
EP1451856A2 (en) * | 2001-11-07 | 2004-09-01 | Pharmacia Corporation | Methods of promoting uptake and nuclear accumulation of polyamides in eukaryotic cells |
US20040038904A1 (en) * | 2002-05-21 | 2004-02-26 | Angela Ogden | Method of treating multiple sclerosis |
AU2003247907A1 (en) * | 2002-07-05 | 2004-01-23 | University Of Chicago | Characterization of biochips containing self-assembled monolayers with maldi-tof-ms |
DE102004034047A1 (de) * | 2004-07-13 | 2006-02-09 | Man Roland Druckmaschinen Ag | Stellvorrichtung für einen Falzwerkszylinder |
US20070116778A1 (en) * | 2005-11-22 | 2007-05-24 | Fierro Arthur A | Antibacterial, antiviral, and antifungal nutritional supplement: a combination of natural or neutraceutical compounds shown to have antibacterial, antiviral, and antifungal properties, to help boost the immune system in humans, and to protect against certain biowarfare diseases |
EA032552B1 (ru) | 2012-03-16 | 2019-06-28 | Дзе Джонс Хопкинс Юниверсити | Препараты с контролируемым высвобождением для доставки ингибиторов hif-1 |
RU2692065C1 (ru) * | 2018-04-05 | 2019-06-20 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Глутатионаммониевые соли o,o-диорганилдитиофосфорных кислот, обладающие антиоксидантной и противоопухолевой активностью |
-
1994
- 1994-05-02 IT ITRM940269A patent/IT1272234B/it active IP Right Grant
-
1995
- 1995-05-02 US US08/432,836 patent/US5646177A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5646177A (en) | 1997-07-08 |
IT1272234B (it) | 1997-06-16 |
ITRM940269A1 (it) | 1995-11-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970530 |