CN1306442A - 造影剂或与造影剂有关的改进 - Google Patents

造影剂或与造影剂有关的改进 Download PDF

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Publication number
CN1306442A
CN1306442A CN99807622A CN99807622A CN1306442A CN 1306442 A CN1306442 A CN 1306442A CN 99807622 A CN99807622 A CN 99807622A CN 99807622 A CN99807622 A CN 99807622A CN 1306442 A CN1306442 A CN 1306442A
Authority
CN
China
Prior art keywords
gas
combination preparation
emulsion
compositions
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN99807622A
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English (en)
Chinese (zh)
Inventor
M·埃里克森
H·妥勒夏格
R·斯科特维特
A·库斯伯特森
J·奥斯坦森
S·弗里格斯塔德
P·朗维德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed Imaging AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging AS filed Critical Nycomed Imaging AS
Publication of CN1306442A publication Critical patent/CN1306442A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Light Receiving Elements (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN99807622A 1998-04-22 1999-04-22 造影剂或与造影剂有关的改进 Pending CN1306442A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9808599.6A GB9808599D0 (en) 1998-04-22 1998-04-22 Improvements in or realting to contrast agents
GB9808599.6 1998-04-22

Publications (1)

Publication Number Publication Date
CN1306442A true CN1306442A (zh) 2001-08-01

Family

ID=10830802

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99807622A Pending CN1306442A (zh) 1998-04-22 1999-04-22 造影剂或与造影剂有关的改进

Country Status (17)

Country Link
US (1) US20040146462A1 (https=)
EP (1) EP1073473B1 (https=)
JP (1) JP2002512206A (https=)
KR (1) KR20010042915A (https=)
CN (1) CN1306442A (https=)
AT (1) ATE375806T1 (https=)
AU (1) AU3617299A (https=)
BR (1) BR9909822A (https=)
CA (1) CA2329175A1 (https=)
DE (1) DE69937341D1 (https=)
GB (1) GB9808599D0 (https=)
HU (1) HUP0102878A3 (https=)
IL (1) IL139147A0 (https=)
NO (1) NO20005250L (https=)
PL (1) PL343464A1 (https=)
WO (1) WO1999053963A1 (https=)
ZA (1) ZA200005789B (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100453050C (zh) * 2005-09-21 2009-01-21 北京市肿瘤防治研究所 提高超声造影图像分辨力的方法和超声造影成像仪
CN108586300A (zh) * 2018-03-28 2018-09-28 成都福柯斯医药技术有限公司 一种s-碘化丁酰硫代胆碱的合成方法
CN113598820A (zh) * 2021-08-18 2021-11-05 南京超维景生物科技有限公司 超声成像方法及装置
CN113769154A (zh) * 2021-03-04 2021-12-10 艾柯医疗器械(北京)有限公司 改进的液体栓塞组合物和相关方法

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804162A (en) * 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
DE10119522A1 (de) * 2001-04-20 2002-12-05 Innovacell Biotechnologie Gmbh Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel
KR101280760B1 (ko) 2002-11-29 2013-07-05 지이 헬스케어 에이에스 초음파 조영 물질
US20070128117A1 (en) * 2003-02-04 2007-06-07 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
JP4670083B2 (ja) 2003-02-04 2011-04-13 ブラッコ・シュイス・ソシエテ・アノニム 超音波造影剤およびその製造方法
JP2007515471A (ja) * 2003-12-22 2007-06-14 ブラッコ・リサーチ・ソシエテ・アノニム 造影イメージング用の活性成分を有する気体封入マイクロベシクルのアセンブリー
CN100563718C (zh) * 2003-12-22 2009-12-02 伯拉考开发股份有限公司 用于反差成像的充气微囊组件
US9248204B2 (en) 2004-08-18 2016-02-02 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
US20080255266A1 (en) * 2007-04-10 2008-10-16 Gc Corporation Dental paste composition having x-ray imaging property
JP4279328B2 (ja) * 2007-05-07 2009-06-17 株式会社日立製作所 超音波撮像システム
WO2009097277A1 (en) * 2008-02-01 2009-08-06 Trustees Of Boston University Cationic contrast agents and methods of use thereof
AU2009241762B2 (en) * 2008-05-02 2015-07-16 Celsense Inc. Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications
EP2470287A4 (en) 2009-08-28 2015-01-21 Univ Columbia SYSTEMS, METHODS AND DEVICES FOR PRODUCING GAS-FILLED MICROBUBBLES
DE102011005444A1 (de) * 2011-03-11 2012-09-13 Innora Gmbh Festes, negatives Röntgenkontrastmittel zur Darstellung des Gastrointestinaltraktes
HUE060034T2 (hu) * 2013-09-27 2023-01-28 Exact Therapeutics As Ultrahanggal közvetített hatóanyag leadás
AP2016009276A0 (en) 2013-12-19 2016-06-30 Bayer Pharma AG Substituted piperidinyl-tetrahydroquinolines and their use as alpha-2c adrenoreceptor antagonists
CN110913769A (zh) * 2017-07-09 2020-03-24 利兰斯坦福初级大学董事会 利用频谱合成来减少斑点的超声成像
EP3678712A4 (en) * 2017-09-07 2021-06-02 Imbiotechnologies Ltd. EMBOLIC AGENTS SENSITIVE TO SOUND
CN114760989A (zh) 2019-10-25 2022-07-15 精准医疗股份有限公司 胰腺癌的治疗
GB2595513B (en) 2020-05-29 2023-03-29 Act Therapeutics Ltd Treatment of infections
GB2605422B (en) 2021-03-31 2025-04-30 Act Therapeutics Ltd Treatment of the central nervous system
GB2629999B (en) 2021-04-21 2025-03-26 Act Therapeutics Ltd Enhancement of treatment with immunotherapeutic agents
EP4261786A1 (en) * 2022-03-28 2023-10-18 Tata Consultancy Services Limited Methods and system for low dose x ray computed tomography perfusion imaging
NO20221187A1 (en) 2022-11-04 2024-05-06 Exact Therapeutics As Method and system for calculating a point estimate of an ultrasound dose
CN116271187B (zh) * 2023-03-21 2025-07-04 湖北科技学院 双模态显影温敏Pickering乳液介入栓塞材料及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580575A (en) * 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US5228446A (en) * 1989-12-22 1993-07-20 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5776429A (en) * 1989-12-22 1998-07-07 Imarx Pharmaceutical Corp. Method of preparing gas-filled microspheres using a lyophilized lipids
US5716597A (en) * 1993-06-04 1998-02-10 Molecular Biosystems, Inc. Emulsions as contrast agents and method of use
EP1550464A1 (en) * 1993-07-30 2005-07-06 IMCOR Pharmaceutical Co. Stabilized microbubble composition for ultrasound
NO940711D0 (no) * 1994-03-01 1994-03-01 Nycomed Imaging As Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
TR199901544T2 (xx) * 1996-10-21 1999-09-21 Nycomed Imaging As Kontrast ajanlar�ndaki veya kontrast ajanlar�yla ilgili geli�meler.
EP0963209A2 (en) * 1996-10-28 1999-12-15 Marsden, John Christopher Improvements in or relating to diagnostic/therapeutic agents
EP0991427A2 (en) * 1996-10-28 2000-04-12 Marsden, John Christopher Improvements in or relating to diagnostic/therapeutic agents
WO1998018497A2 (en) * 1996-10-28 1998-05-07 Nycomed Imaging As Contrast agents

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100453050C (zh) * 2005-09-21 2009-01-21 北京市肿瘤防治研究所 提高超声造影图像分辨力的方法和超声造影成像仪
CN108586300A (zh) * 2018-03-28 2018-09-28 成都福柯斯医药技术有限公司 一种s-碘化丁酰硫代胆碱的合成方法
CN108586300B (zh) * 2018-03-28 2020-03-17 成都福柯斯医药技术有限公司 一种s-碘化丁酰硫代胆碱的合成方法
CN113769154A (zh) * 2021-03-04 2021-12-10 艾柯医疗器械(北京)有限公司 改进的液体栓塞组合物和相关方法
CN113598820A (zh) * 2021-08-18 2021-11-05 南京超维景生物科技有限公司 超声成像方法及装置

Also Published As

Publication number Publication date
JP2002512206A (ja) 2002-04-23
US20040146462A1 (en) 2004-07-29
HUP0102878A2 (hu) 2002-03-28
AU3617299A (en) 1999-11-08
DE69937341D1 (de) 2007-11-29
NO20005250D0 (no) 2000-10-19
BR9909822A (pt) 2000-12-19
PL343464A1 (en) 2001-08-13
ZA200005789B (en) 2001-07-30
CA2329175A1 (en) 1999-10-28
ATE375806T1 (de) 2007-11-15
WO1999053963A1 (en) 1999-10-28
KR20010042915A (ko) 2001-05-25
IL139147A0 (en) 2001-11-25
EP1073473A1 (en) 2001-02-07
GB9808599D0 (en) 1998-06-24
NO20005250L (no) 2000-12-18
HUP0102878A3 (en) 2002-12-28
EP1073473B1 (en) 2007-10-17

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