JP2002512206A - 改良された造影剤 - Google Patents

改良された造影剤

Info

Publication number
JP2002512206A
JP2002512206A JP2000544366A JP2000544366A JP2002512206A JP 2002512206 A JP2002512206 A JP 2002512206A JP 2000544366 A JP2000544366 A JP 2000544366A JP 2000544366 A JP2000544366 A JP 2000544366A JP 2002512206 A JP2002512206 A JP 2002512206A
Authority
JP
Japan
Prior art keywords
gas
combination preparation
composition
preparation according
emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2000544366A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002512206A5 (https=
Inventor
モーテン・エーリクセン
ヘルゲ・トーレスハウグ
ロウアール・スクルトヴェイト
アラン・カスバートソン
ヨニー・エーステンセン
シーグムンド・フリグスタード
ポール・ロングヴェド
Original Assignee
ニユコメド・イメージング・アクシエセルカペト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ニユコメド・イメージング・アクシエセルカペト filed Critical ニユコメド・イメージング・アクシエセルカペト
Publication of JP2002512206A publication Critical patent/JP2002512206A/ja
Publication of JP2002512206A5 publication Critical patent/JP2002512206A5/ja
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Light Receiving Elements (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2000544366A 1998-04-22 1999-04-22 改良された造影剤 Abandoned JP2002512206A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9808599.6A GB9808599D0 (en) 1998-04-22 1998-04-22 Improvements in or realting to contrast agents
GB9808599.6 1998-04-22
PCT/GB1999/001221 WO1999053963A1 (en) 1998-04-22 1999-04-22 Improvements in or relating to contrast agents

Publications (2)

Publication Number Publication Date
JP2002512206A true JP2002512206A (ja) 2002-04-23
JP2002512206A5 JP2002512206A5 (https=) 2006-06-15

Family

ID=10830802

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000544366A Abandoned JP2002512206A (ja) 1998-04-22 1999-04-22 改良された造影剤

Country Status (17)

Country Link
US (1) US20040146462A1 (https=)
EP (1) EP1073473B1 (https=)
JP (1) JP2002512206A (https=)
KR (1) KR20010042915A (https=)
CN (1) CN1306442A (https=)
AT (1) ATE375806T1 (https=)
AU (1) AU3617299A (https=)
BR (1) BR9909822A (https=)
CA (1) CA2329175A1 (https=)
DE (1) DE69937341D1 (https=)
GB (1) GB9808599D0 (https=)
HU (1) HUP0102878A3 (https=)
IL (1) IL139147A0 (https=)
NO (1) NO20005250L (https=)
PL (1) PL343464A1 (https=)
WO (1) WO1999053963A1 (https=)
ZA (1) ZA200005789B (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007515471A (ja) * 2003-12-22 2007-06-14 ブラッコ・リサーチ・ソシエテ・アノニム 造影イメージング用の活性成分を有する気体封入マイクロベシクルのアセンブリー
JP2007515470A (ja) * 2003-12-22 2007-06-14 ブラッコ・リサーチ・ソシエテ・アノニム 造影イメージング用の気体封入マイクロベシクル・アセンブリー
US9248204B2 (en) 2004-08-18 2016-02-02 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
US9364569B2 (en) 2003-02-04 2016-06-14 Bracco Suisse S.A. Ultrasound contrast agents and process for the preparation thereof
JP2016532718A (ja) * 2013-09-27 2016-10-20 フェニックス・ソリューションズ・アーエス 超音波により媒介される薬物送達
JP2023529237A (ja) * 2020-05-29 2023-07-07 アクト セラピューティクス リミテッド 感染の治療

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804162A (en) * 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
DE10119522A1 (de) * 2001-04-20 2002-12-05 Innovacell Biotechnologie Gmbh Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel
KR101280760B1 (ko) 2002-11-29 2013-07-05 지이 헬스케어 에이에스 초음파 조영 물질
US20070128117A1 (en) * 2003-02-04 2007-06-07 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
CN100453050C (zh) * 2005-09-21 2009-01-21 北京市肿瘤防治研究所 提高超声造影图像分辨力的方法和超声造影成像仪
US20080255266A1 (en) * 2007-04-10 2008-10-16 Gc Corporation Dental paste composition having x-ray imaging property
JP4279328B2 (ja) * 2007-05-07 2009-06-17 株式会社日立製作所 超音波撮像システム
WO2009097277A1 (en) * 2008-02-01 2009-08-06 Trustees Of Boston University Cationic contrast agents and methods of use thereof
AU2009241762B2 (en) * 2008-05-02 2015-07-16 Celsense Inc. Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications
EP2470287A4 (en) 2009-08-28 2015-01-21 Univ Columbia SYSTEMS, METHODS AND DEVICES FOR PRODUCING GAS-FILLED MICROBUBBLES
DE102011005444A1 (de) * 2011-03-11 2012-09-13 Innora Gmbh Festes, negatives Röntgenkontrastmittel zur Darstellung des Gastrointestinaltraktes
AP2016009276A0 (en) 2013-12-19 2016-06-30 Bayer Pharma AG Substituted piperidinyl-tetrahydroquinolines and their use as alpha-2c adrenoreceptor antagonists
CN110913769A (zh) * 2017-07-09 2020-03-24 利兰斯坦福初级大学董事会 利用频谱合成来减少斑点的超声成像
EP3678712A4 (en) * 2017-09-07 2021-06-02 Imbiotechnologies Ltd. EMBOLIC AGENTS SENSITIVE TO SOUND
CN108586300B (zh) * 2018-03-28 2020-03-17 成都福柯斯医药技术有限公司 一种s-碘化丁酰硫代胆碱的合成方法
CN114760989A (zh) 2019-10-25 2022-07-15 精准医疗股份有限公司 胰腺癌的治疗
US11801058B2 (en) * 2021-03-04 2023-10-31 Accumedical Beijing Ltd. Liquid embolic compositions
GB2605422B (en) 2021-03-31 2025-04-30 Act Therapeutics Ltd Treatment of the central nervous system
GB2629999B (en) 2021-04-21 2025-03-26 Act Therapeutics Ltd Enhancement of treatment with immunotherapeutic agents
CN113598820B (zh) * 2021-08-18 2025-09-23 南京超微影医疗科技有限公司 超声成像方法及装置
EP4261786A1 (en) * 2022-03-28 2023-10-18 Tata Consultancy Services Limited Methods and system for low dose x ray computed tomography perfusion imaging
NO20221187A1 (en) 2022-11-04 2024-05-06 Exact Therapeutics As Method and system for calculating a point estimate of an ultrasound dose
CN116271187B (zh) * 2023-03-21 2025-07-04 湖北科技学院 双模态显影温敏Pickering乳液介入栓塞材料及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580575A (en) * 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US5228446A (en) * 1989-12-22 1993-07-20 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5776429A (en) * 1989-12-22 1998-07-07 Imarx Pharmaceutical Corp. Method of preparing gas-filled microspheres using a lyophilized lipids
US5716597A (en) * 1993-06-04 1998-02-10 Molecular Biosystems, Inc. Emulsions as contrast agents and method of use
EP1550464A1 (en) * 1993-07-30 2005-07-06 IMCOR Pharmaceutical Co. Stabilized microbubble composition for ultrasound
NO940711D0 (no) * 1994-03-01 1994-03-01 Nycomed Imaging As Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
TR199901544T2 (xx) * 1996-10-21 1999-09-21 Nycomed Imaging As Kontrast ajanlar�ndaki veya kontrast ajanlar�yla ilgili geli�meler.
EP0963209A2 (en) * 1996-10-28 1999-12-15 Marsden, John Christopher Improvements in or relating to diagnostic/therapeutic agents
EP0991427A2 (en) * 1996-10-28 2000-04-12 Marsden, John Christopher Improvements in or relating to diagnostic/therapeutic agents
WO1998018497A2 (en) * 1996-10-28 1998-05-07 Nycomed Imaging As Contrast agents

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9364569B2 (en) 2003-02-04 2016-06-14 Bracco Suisse S.A. Ultrasound contrast agents and process for the preparation thereof
JP2007515471A (ja) * 2003-12-22 2007-06-14 ブラッコ・リサーチ・ソシエテ・アノニム 造影イメージング用の活性成分を有する気体封入マイクロベシクルのアセンブリー
JP2007515470A (ja) * 2003-12-22 2007-06-14 ブラッコ・リサーチ・ソシエテ・アノニム 造影イメージング用の気体封入マイクロベシクル・アセンブリー
JP2012051932A (ja) * 2003-12-22 2012-03-15 Bracco Suisse Sa 造影イメージング用の気体封入マイクロベシクル・アセンブリー
US9750821B2 (en) 2003-12-22 2017-09-05 Bracco Suisse S.A. Gas-filled microvesicle assembly for contrast imaging
US9248204B2 (en) 2004-08-18 2016-02-02 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
US10076580B2 (en) 2004-08-18 2018-09-18 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
JP2016532718A (ja) * 2013-09-27 2016-10-20 フェニックス・ソリューションズ・アーエス 超音波により媒介される薬物送達
JP2020114846A (ja) * 2013-09-27 2020-07-30 フェニックス・ソリューションズ・アーエス 超音波により媒介される薬物送達
JP7042862B2 (ja) 2013-09-27 2022-03-28 イグザクト・セラピューティクス・アーエス 超音波により媒介される薬物送達
JP2023529237A (ja) * 2020-05-29 2023-07-07 アクト セラピューティクス リミテッド 感染の治療

Also Published As

Publication number Publication date
CN1306442A (zh) 2001-08-01
US20040146462A1 (en) 2004-07-29
HUP0102878A2 (hu) 2002-03-28
AU3617299A (en) 1999-11-08
DE69937341D1 (de) 2007-11-29
NO20005250D0 (no) 2000-10-19
BR9909822A (pt) 2000-12-19
PL343464A1 (en) 2001-08-13
ZA200005789B (en) 2001-07-30
CA2329175A1 (en) 1999-10-28
ATE375806T1 (de) 2007-11-15
WO1999053963A1 (en) 1999-10-28
KR20010042915A (ko) 2001-05-25
IL139147A0 (en) 2001-11-25
EP1073473A1 (en) 2001-02-07
GB9808599D0 (en) 1998-06-24
NO20005250L (no) 2000-12-18
HUP0102878A3 (en) 2002-12-28
EP1073473B1 (en) 2007-10-17

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Legal Events

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A521 Request for written amendment filed

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Effective date: 20060407

A621 Written request for application examination

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A762 Written abandonment of application

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