ZA200005789B - Ultrasound contrast agents useful as deposited perfusion tracers. - Google Patents
Ultrasound contrast agents useful as deposited perfusion tracers.Info
- Publication number
- ZA200005789B ZA200005789B ZA200005789A ZA200005789A ZA200005789B ZA 200005789 B ZA200005789 B ZA 200005789B ZA 200005789 A ZA200005789 A ZA 200005789A ZA 200005789 A ZA200005789 A ZA 200005789A ZA 200005789 B ZA200005789 B ZA 200005789B
- Authority
- ZA
- South Africa
- Prior art keywords
- dispersed
- gas
- preparations
- perfusion
- material present
- Prior art date
Links
- 230000010412 perfusion Effects 0.000 title abstract 4
- 239000002961 echo contrast media Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 3
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 239000002126 C01EB10 - Adenosine Substances 0.000 abstract 1
- 229960005305 adenosine Drugs 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 239000002872 contrast media Substances 0.000 abstract 1
- 238000009792 diffusion process Methods 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 230000002107 myocardial effect Effects 0.000 abstract 1
- 210000004165 myocardium Anatomy 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
- 238000012800 visualization Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Light Receiving Elements (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9808599.6A GB9808599D0 (en) | 1998-04-22 | 1998-04-22 | Improvements in or realting to contrast agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200005789B true ZA200005789B (en) | 2001-07-30 |
Family
ID=10830802
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200005789A ZA200005789B (en) | 1998-04-22 | 2000-10-18 | Ultrasound contrast agents useful as deposited perfusion tracers. |
Country Status (17)
Country | Link |
---|---|
US (1) | US20040146462A1 (xx) |
EP (1) | EP1073473B1 (xx) |
JP (1) | JP2002512206A (xx) |
KR (1) | KR20010042915A (xx) |
CN (1) | CN1306442A (xx) |
AT (1) | ATE375806T1 (xx) |
AU (1) | AU3617299A (xx) |
BR (1) | BR9909822A (xx) |
CA (1) | CA2329175A1 (xx) |
DE (1) | DE69937341D1 (xx) |
GB (1) | GB9808599D0 (xx) |
HU (1) | HUP0102878A3 (xx) |
IL (1) | IL139147A0 (xx) |
NO (1) | NO20005250L (xx) |
PL (1) | PL343464A1 (xx) |
WO (1) | WO1999053963A1 (xx) |
ZA (1) | ZA200005789B (xx) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5804162A (en) * | 1995-06-07 | 1998-09-08 | Alliance Pharmaceutical Corp. | Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients |
DE10119522A1 (de) * | 2001-04-20 | 2002-12-05 | Innovacell Biotechnologie Gmbh | Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel |
KR20050072496A (ko) | 2002-11-29 | 2005-07-11 | 아머샴 헬스 에이에스 | 초음파 촬영 방법 |
US20070128117A1 (en) * | 2003-02-04 | 2007-06-07 | Bracco International B.V. | Ultrasound contrast agents and process for the preparation thereof |
ES2352087T3 (es) | 2003-02-04 | 2011-02-15 | Bracco Suisse Sa | Agentes de contraste para ultrasonido y procedimiento para la preparación de los mismos. |
JP5513708B2 (ja) * | 2003-12-22 | 2014-06-04 | ブラッコ・シュイス・ソシエテ・アノニム | 造影イメージング用の気体封入マイクロベシクル・アセンブリー |
CN1897978B (zh) * | 2003-12-22 | 2011-11-23 | 博莱科瑞士股份有限公司 | 具有用于反差成像的活性组分的充气微囊组件 |
JP4837663B2 (ja) | 2004-08-18 | 2011-12-14 | ブラッコ・シュイス・ソシエテ・アノニム | 造影画像化のためのガス充填微小胞組成物 |
US8153435B1 (en) | 2005-03-30 | 2012-04-10 | Tracer Detection Technology Corp. | Methods and articles for identifying objects using encapsulated perfluorocarbon tracers |
CN100453050C (zh) * | 2005-09-21 | 2009-01-21 | 北京市肿瘤防治研究所 | 提高超声造影图像分辨力的方法和超声造影成像仪 |
US20080255266A1 (en) * | 2007-04-10 | 2008-10-16 | Gc Corporation | Dental paste composition having x-ray imaging property |
JP4279328B2 (ja) * | 2007-05-07 | 2009-06-17 | 株式会社日立製作所 | 超音波撮像システム |
EP2247314A4 (en) * | 2008-02-01 | 2013-11-27 | Univ Boston | CATIONIC CONTRASTING AGENTS AND METHOD FOR THEIR USE |
US20110110863A1 (en) * | 2008-05-02 | 2011-05-12 | Celsense, Inc. | Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications |
US10058837B2 (en) | 2009-08-28 | 2018-08-28 | The Trustees Of Columbia University In The City Of New York | Systems, methods, and devices for production of gas-filled microbubbles |
DE102011005444A1 (de) * | 2011-03-11 | 2012-09-13 | Innora Gmbh | Festes, negatives Röntgenkontrastmittel zur Darstellung des Gastrointestinaltraktes |
ES2927884T3 (es) | 2013-09-27 | 2022-11-11 | Exact Therapeutics As | Administración de fármacos mediada por ultrasonidos |
JOP20200052A1 (ar) * | 2013-12-19 | 2017-06-16 | Bayer Pharma AG | بيبريدينيل تتراهيدرو كوينولينات مستبدلة واستخدامها كمعضدات مستقبل أدريني ألفا- 2c |
WO2019014070A1 (en) * | 2017-07-09 | 2019-01-17 | The Board Of Trustees Of The Leland Stanford Junior University | ULTRASOUND IMAGING COMPRISING A SPECTRAL COMPOSITION FOR TAVELURE REDUCTION |
CN111201043A (zh) * | 2017-09-07 | 2020-05-26 | Im生物技术有限公司 | 声应性栓塞剂 |
CN108586300B (zh) * | 2018-03-28 | 2020-03-17 | 成都福柯斯医药技术有限公司 | 一种s-碘化丁酰硫代胆碱的合成方法 |
US20220378692A1 (en) | 2019-10-25 | 2022-12-01 | Exact Therapeutics As | Treatment of pancreatic cancer |
GB2595513B (en) | 2020-05-29 | 2023-03-29 | Act Therapeutics Ltd | Treatment of infections |
US11801058B2 (en) * | 2021-03-04 | 2023-10-31 | Accumedical Beijing Ltd. | Liquid embolic compositions |
GB2605422A (en) | 2021-03-31 | 2022-10-05 | Act Therapeutics Ltd | Treatment of the central nervous system |
GB2605996B (en) | 2021-04-21 | 2024-09-25 | Act Therapeutics Ltd | Enhancement of treatment with immunotherapeutic agents |
EP4261786A1 (en) * | 2022-03-28 | 2023-10-18 | Tata Consultancy Services Limited | Methods and system for low dose x ray computed tomography perfusion imaging |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5580575A (en) * | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
US5776429A (en) * | 1989-12-22 | 1998-07-07 | Imarx Pharmaceutical Corp. | Method of preparing gas-filled microspheres using a lyophilized lipids |
US5228446A (en) * | 1989-12-22 | 1993-07-20 | Unger Evan C | Gas filled liposomes and their use as ultrasonic contrast agents |
US5716597A (en) * | 1993-06-04 | 1998-02-10 | Molecular Biosystems, Inc. | Emulsions as contrast agents and method of use |
DE69434119T3 (de) * | 1993-07-30 | 2011-05-05 | Imcor Pharmaceutical Co., San Diego | Stabilisierte mikrogasbläschen-zusammensetzungen für echographie |
NO940711D0 (no) * | 1994-03-01 | 1994-03-01 | Nycomed Imaging As | Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging |
US5846517A (en) * | 1996-09-11 | 1998-12-08 | Imarx Pharmaceutical Corp. | Methods for diagnostic imaging using a renal contrast agent and a vasodilator |
PL332820A1 (en) * | 1996-10-21 | 1999-10-11 | Nycomed Imaging As | Improved contrast media |
WO1998018495A2 (en) * | 1996-10-28 | 1998-05-07 | Marsden, John, Christopher | Improvements in or relating to diagnostic/therapeutic agents |
WO1998018498A2 (en) * | 1996-10-28 | 1998-05-07 | Marsden, John, Christopher | Improvements in or relating to diagnostic/therapeutic agents |
WO1998018497A2 (en) * | 1996-10-28 | 1998-05-07 | Nycomed Imaging As | Contrast agents |
-
1998
- 1998-04-22 GB GBGB9808599.6A patent/GB9808599D0/en not_active Ceased
-
1999
- 1999-04-22 PL PL99343464A patent/PL343464A1/xx unknown
- 1999-04-22 HU HU0102878A patent/HUP0102878A3/hu unknown
- 1999-04-22 WO PCT/GB1999/001221 patent/WO1999053963A1/en active IP Right Grant
- 1999-04-22 KR KR1020007011727A patent/KR20010042915A/ko not_active Application Discontinuation
- 1999-04-22 IL IL13914799A patent/IL139147A0/xx unknown
- 1999-04-22 AT AT99918133T patent/ATE375806T1/de not_active IP Right Cessation
- 1999-04-22 CN CN99807622A patent/CN1306442A/zh active Pending
- 1999-04-22 CA CA002329175A patent/CA2329175A1/en not_active Abandoned
- 1999-04-22 JP JP2000544366A patent/JP2002512206A/ja not_active Abandoned
- 1999-04-22 BR BR9909822-9A patent/BR9909822A/pt not_active IP Right Cessation
- 1999-04-22 DE DE69937341T patent/DE69937341D1/de not_active Expired - Lifetime
- 1999-04-22 EP EP99918133A patent/EP1073473B1/en not_active Expired - Lifetime
- 1999-04-22 AU AU36172/99A patent/AU3617299A/en not_active Abandoned
-
2000
- 2000-10-18 ZA ZA200005789A patent/ZA200005789B/xx unknown
- 2000-10-19 NO NO20005250A patent/NO20005250L/no not_active Application Discontinuation
-
2003
- 2003-11-19 US US10/717,196 patent/US20040146462A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HUP0102878A3 (en) | 2002-12-28 |
EP1073473A1 (en) | 2001-02-07 |
WO1999053963A1 (en) | 1999-10-28 |
IL139147A0 (en) | 2001-11-25 |
HUP0102878A2 (hu) | 2002-03-28 |
NO20005250D0 (no) | 2000-10-19 |
US20040146462A1 (en) | 2004-07-29 |
ATE375806T1 (de) | 2007-11-15 |
GB9808599D0 (en) | 1998-06-24 |
AU3617299A (en) | 1999-11-08 |
JP2002512206A (ja) | 2002-04-23 |
PL343464A1 (en) | 2001-08-13 |
CN1306442A (zh) | 2001-08-01 |
BR9909822A (pt) | 2000-12-19 |
NO20005250L (no) | 2000-12-18 |
EP1073473B1 (en) | 2007-10-17 |
DE69937341D1 (de) | 2007-11-29 |
CA2329175A1 (en) | 1999-10-28 |
KR20010042915A (ko) | 2001-05-25 |
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