CN1292268A

CN1292268A - Medicine for curing tinea unguium

Info

Publication number: CN1292268A
Application number: CN 00105966
Authority: CN
Inventors: 缪振兴
Original assignee: Individual
Current assignee: Individual
Priority date: 2000-04-24
Filing date: 2000-04-24
Publication date: 2001-04-25
Anticipated expiration: 2020-04-24
Also published as: CN1110307C

Abstract

The medicine for external application for curing onychomycosis, tinea manuum and tinea pedis is made up by using several Chinese medicinal materials of schizonepeta, ledebouriella root, flavescent sophora root, phellodendron bark, coptis root, kochia fruit, calcined alum and rose-of-Sharon root bark, etc. and soaking them in acetic acid solution for a week. Said invented product possesses strong furgicidal action, its therapeutic effect is high, application is safe, convenient, its preparation method is simple, and, it has no toxic side effect.

Description

Medicine for curing tinea unguium

The invention belongs to topical drug, particularly the topical drug of treatment tinea unguium.

" the special medicine box of handkerchief " is that Guizhou Shenqi Pharmaceutical Co., Ltd produces, and treats the main medicine for external use of tinea unguium at present, and with regard to its effect, cure rate is low, relapse rate height, and Therapeutic Method complexity, and common people can not adhere to.Be with regard to its reason: on the one hand it has ignored root-hands, the tinea pedis that treatment causes tinea unguium; " JIAOXIAN YICIJING " in the Clinical Practice proof medicine box in fact can not be effected a radical cure hands, tinea pedis on the other hand.

Purpose of the present invention is developed a kind of specially good effect external used medicine for the treatment of tinea unguium, tinea manus and pedis, and it is formulated through science by plurality of Chinese.

Technical scheme of the present invention: the medicine Main Ingredients and Appearance is Herba Schizonepetae, Radix Saposhnikoviae, each 5-10% of Radix Sophorae Flavescentis, Cortex Phellodendri, Rhizoma Coptidis, the Fructus Kochiae, each 13-20% of dried Alumen, Cortex Pseudolaricis, Fructus Cnidii, the Radix Stemonae, Fructus Zanthoxyli, each 3-12% of Flos Caryophylli, Cortex Dictamni, each 4-13% of Cortex Lycii cooperate, altogether the 170-360 gram, grind to the powder altogether, cross 120 mesh sieves, be soaked among the 10-30% acetic acid solution 1000-2000ml week, its supernatant is the tinea unguium ichor, sticks with paste for Jiaxianling-medicine for curing onychomycosis in the pasty state below.

Advantage of the present invention is that the fungus on tinea unguium and hands, the foot is had stronger killing action, the curative effect height, and safety easy to use, method of treatment is simple, and human body is had no side effect, and can effect a radical cure tinea unguium and hands, tinea pedis.

Embodiment one (I type): Herba Schizonepetae 10g, Radix Saposhnikoviae 10g, Radix Sophorae Flavescentis 10g, Cortex Phellodendri 5g, Fructus Kochiae 25g, Rhizoma Coptidis 25g, dried Alumen 25g, Cortex Pseudolaricis 6g, Fructus Cnidii 6g, Radix Stemonae 6g, Fructus Zanthoxyli 6g, Flos Caryophylli 6g, Cortex Dictamni 8g, Cortex Lycii 8g, close 176 the gram grind to the powder altogether, cross 120 mesh sieves, be dissolved among the 10% acetic acid solution 1000ml, one week, supernatant is " Jiaxianling-medicine for curing onychomycosis " liquid, be that " Jiaxianling-medicine for curing onychomycosis " stuck with paste below, I type tinea unguium ichor is applicable to child and tenderer hands, the tinea pedis patient of skin, and " Jiaxianling-medicine for curing onychomycosis " stuck with paste and be applicable to the atrophic type patient.

Embodiment two (II type), Herba Schizonepetae 20g, Radix Saposhnikoviae 20g, Radix Sophorae Flavescentis 20g, Cortex Phellodendri 40g, Fructus Kochiae 26g, Rhizoma Coptidis 40g, dried Alumen 40g, Cortex Pseudolaricis 30g, Fructus Cnidii 30g, Radix Stemonae 8g, Fructus Zanthoxyli 8g, Flos Caryophylli 6g, Cortex Dictamni 20g, Cortex Lycii 20g, close 358 the gram grind to the powder altogether, cross 120 mesh sieves, be dissolved among the 30% acetic acid solution 2000ml, one week, supernatant is " Jiaxianling-medicine for curing onychomycosis " liquid, be that " Jiaxianling-medicine for curing onychomycosis " stuck with paste below, II type tinea unguium ichor is applicable to incrassation type tinea unguium and hands, tinea pedis patient especially.

Therapeutic Method: stick with paste directly to spread on Jiaxianling-medicine for curing onychomycosis and suffer from the first, with the wrapping of plastic sheeting fingerstall, medicine easily is penetrated on the nail matrix then, keep 1～3 day (decide) at every turn, treated once in every month, can heal for three times according to temperature.When treatment hands, tinea pedis, directly act on the affected part with the gauze that speckles with the tinea unguium ichor, with disposable plastic glove or the wrapping of foot cover, according to the state of an illness each about one hour, can heal for 2～3 times, treatment once is a course of treatment.It is emphasized that: when treatment tinea unguium, must cure hands, tinea pedis simultaneously!

Criterion of therapeutical effect: (1) cures: fingernail is level and smooth and glossy, nothing is damaged, hands, sufficient light

Sliding nothing is damaged.Microscopy fungus (-).

(2) effective: fingernail is smooth, and poor transparency makes progress before controlling.

(3) invalid: no change before and after the treatment.

Cure rate: 98.30% (seeing attached list).

Model case:

Zhao * *, the woman, 50 years old, the patient came here to go to a doctor because of suffering from tinea unguium 15 years.Look into both hands and suffer from the tinea manuum, right hand middle finger, forefinger, thumb and the deck atrophy of the left hand the five fingers are turned white, and (atrophic type) separated on the deck with nail matrix.Spread on thick 2mm on the disease first so give " Jiaxianling-medicine for curing onychomycosis " paste; protect surrounding skin with adhesive plaster around the sick first; top covered with plastic film fingerstall; the reuse immobilization with adhesive tape; remove dressing two days later; observe nail matrix after ten days and revealed new first; be cut into hand-type with the gauze that speckles with the tinea unguium ichor after 20 days and spread on both hands; the wrapping of external disposable glove was removed after one hour, did not contact with water in 24 hours; through two course of therapy; sick first is all decorporated after three months, has level and smooth and glossiness new first and grows, and both hands also smoothly as before.Follow up a case by regular visits to not recurrence in 2 years.

Pharmacology analysis: tinea unguium is a kind of common multiple cutaneous disease (especially in China south), and this disease has state of an illness stubbornness, outbreak repeatedly, and the course of disease is long, is difficult for the characteristics of thoroughly curing.Radix Sophorae Flavescentis, Cortex Pseudolaricis, Fructus Cnidii, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, river uncle, anti-wind energy are dispeled the wind in the Jiaxianling-medicine for curing onychomycosis, parasite killing, antipruritic, the stronger mycocidal effect that presses down is arranged, Flos Caryophylli not only has antifungic action, and staphylococcus aureus is had inhibitory action, and acetic acid can make little vasodilation, increase cutaneous circulation, and can kill fungus, antibacterial on the skin, and make skin smooth, also be that a kind of splendid skin advances agent thoroughly simultaneously.Dried Alumen has convergence, and the full side of dampness, itching-relieving action collects the product of sterilization, antipruritic, dispeiling pathogenic wind and removing dampness in a stove, so power is specially imitated speed, method of treatment is simple, finds no skin allergy and toxic and side effects clinically, welcome by patient and his family.

Subordinate list: treatment tinea unguium classification observation of curative effect

Classification	The example number	Recovery from illness	Effectively	Invalid	Toxicity	The course of treatment
Classification	Incrassation type	38	35	2	1	—	3
Atrophic type	92	92	—	—	—	1～2
Topical type	46	46	—	—	—	1

Claims

1, a kind of medicine for curing tinea unguium is characterized in that the medicine Main Ingredients and Appearance is:

Herba Schizonepetae, Radix Saposhnikoviae, each 5-10% of Radix Sophorae Flavescentis, Cortex Phellodendri, Rhizoma Coptidis, the Fructus Kochiae, each 13-20% of dried Alumen, Cortex Pseudolaricis, Fructus Cnidii, the Radix Stemonae, Fructus Zanthoxyli, each 3-12% of Flos Caryophylli, Cortex Dictamni, each 4-13% of Cortex Lycii cooperate, altogether the 170-360 gram, grind to the powder altogether, cross 120 mesh sieves, be soaked among the 10-30% acetic acid solution 1000-2000ml week, its supernatant is the tinea unguium ichor, sticks with paste for Jiaxianling-medicine for curing onychomycosis in the pasty state below.