CN108743855A - A kind of external used medicine and preparation method thereof for curing onychomycosis - Google Patents
A kind of external used medicine and preparation method thereof for curing onychomycosis Download PDFInfo
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- CN108743855A CN108743855A CN201810970035.6A CN201810970035A CN108743855A CN 108743855 A CN108743855 A CN 108743855A CN 201810970035 A CN201810970035 A CN 201810970035A CN 108743855 A CN108743855 A CN 108743855A
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- onychomycosis
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- camphor
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- 239000003814 drug Substances 0.000 title claims abstract description 59
- 208000010195 Onychomycosis Diseases 0.000 title claims abstract description 35
- 201000005882 tinea unguium Diseases 0.000 title claims abstract description 35
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims abstract description 19
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 19
- 241001645380 Bassia scoparia Species 0.000 claims abstract description 19
- 241000723346 Cinnamomum camphora Species 0.000 claims abstract description 19
- 241001671204 Stemona Species 0.000 claims abstract description 19
- 206010043866 Tinea capitis Diseases 0.000 claims abstract description 19
- 229960000846 camphor Drugs 0.000 claims abstract description 19
- 229930008380 camphor Natural products 0.000 claims abstract description 19
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 19
- 208000009189 tinea favosa Diseases 0.000 claims abstract description 19
- 240000003705 Senecio vulgaris Species 0.000 claims abstract description 18
- 230000009194 climbing Effects 0.000 claims abstract description 18
- 229940079593 drug Drugs 0.000 claims abstract description 18
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 16
- 239000007921 spray Substances 0.000 claims abstract description 8
- 239000007788 liquid Substances 0.000 claims abstract description 7
- 239000008361 herbal raw material Substances 0.000 claims abstract description 4
- 235000019640 taste Nutrition 0.000 claims abstract description 4
- 241000245665 Taraxacum Species 0.000 claims description 14
- 238000009835 boiling Methods 0.000 claims description 12
- 238000001816 cooling Methods 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 4
- DSSYKIVIOFKYAU-XVKPBYJWSA-N (1s,4r)-4,7,7-trimethylbicyclo[2.2.1]heptan-3-one Chemical compound C1C[C@@]2(C)C(=O)C[C@H]1C2(C)C DSSYKIVIOFKYAU-XVKPBYJWSA-N 0.000 claims description 3
- 238000011049 filling Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000007654 immersion Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 238000002791 soaking Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 238000003860 storage Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 241000043511 Boronia serrulata Species 0.000 claims 1
- 235000018081 Hibiscus syriacus Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 10
- 239000003973 paint Substances 0.000 abstract description 4
- 230000035515 penetration Effects 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 240000001949 Taraxacum officinale Species 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 229940126701 oral medication Drugs 0.000 abstract description 2
- 230000000638 stimulation Effects 0.000 abstract description 2
- 239000000796 flavoring agent Substances 0.000 description 8
- 235000019634 flavors Nutrition 0.000 description 8
- 235000009508 confectionery Nutrition 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 229910052737 gold Inorganic materials 0.000 description 3
- 239000010931 gold Substances 0.000 description 3
- 206010067484 Adverse reaction Diseases 0.000 description 2
- 241001480043 Arthrodermataceae Species 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 2
- 230000006838 adverse reaction Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000037304 dermatophytes Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 description 2
- 229960002722 terbinafine Drugs 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- MQHLMHIZUIDKOO-OKZBNKHCSA-N (2R,6S)-2,6-dimethyl-4-[(2S)-2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine Chemical compound C1=CC(C(C)(C)CC)=CC=C1C[C@H](C)CN1C[C@@H](C)O[C@@H](C)C1 MQHLMHIZUIDKOO-OKZBNKHCSA-N 0.000 description 1
- VHVPQPYKVGDNFY-DFMJLFEVSA-N 2-[(2r)-butan-2-yl]-4-[4-[4-[4-[[(2r,4s)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Chemical compound O=C1N([C@H](C)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(OC3)C=3C(=CC(Cl)=CC=3)Cl)=CC=2)C=C1 VHVPQPYKVGDNFY-DFMJLFEVSA-N 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000235342 Saccharomycetes Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000007605 air drying Methods 0.000 description 1
- 229960003204 amorolfine Drugs 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001857 anti-mycotic effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000002543 antimycotic Substances 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- VURKTKHHTUWVPW-UHFFFAOYSA-N copper nitroxyl Chemical compound [Cu].N=O VURKTKHHTUWVPW-UHFFFAOYSA-N 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 229960004884 fluconazole Drugs 0.000 description 1
- RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 229960004130 itraconazole Drugs 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
Classifications
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
A kind of external used medicine and preparation method thereof for curing onychomycosis is suitable for onychomycosis patient and uses.The external used medicine of the present invention for curing onychomycosis is made of using kuh-seng, the windproof, tuber of stemona, Cortex Phellodendri, frutus cnidii, climbing groundsel, honeysuckle, Fructus Forsythiae, corter pseudolaricis, dandelion, favus skin, the fruit of summer cypress, 13 taste herbal raw material of camphor.The Chinese medicine preparation of the present invention for curing onychomycosis is liquid state, and directly spray is put on the affected area of patient, easy to use, penetration is strong, has no toxic side effect, and curative effect is apparent, reduce the inconvenience brought to minimal invasive treatment to the stimulation of human body and other drugs reaction and Western medicine paint using oral drugs.Manufacture craft of the present invention is simple, at low cost, easily promotes.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, a kind of external used medicine that curing onychomycosis and its preparation side are related generally to
Method.
Background technology
Onychomycosis is commonly called as " onychomycosis ", refers to that dermatophytes invades disease caused under deck or first.Onychomycosis is by skin
The fungus-caused first infection such as tinea bacterium, saccharomycete and non-dermatophytes.Currently, the therapy for onychomycosis patient and use
There are many drug, and endo-medicine has oral terbinafine, Itraconazole, takes Fluconazole.It is big that these drugs individually take dose,
Administration time is long, and patient is also easy to produce adverse reaction.Topical therapy is exactly to select Terbinafine tincture, Amorolfine first liniment, ring pyrrole
The antimycotic externally applied drugs such as ketoamine copper first paint are to disease sites partial smearing, and patient is after smearing drug to normal life and work
Bring many inconvenience.For prior art deficiency existing during curing onychomycosis, inventor develops and proposes one
Kind cures the preparation method of the drug and the drug of onychomycosis using traditional Chinese medicine liquid, with overcome the deficiencies in the prior art.
Invention content
In view of deficiency of the prior art, the present invention is according to inducement caused by onychomycosis, relieve heat damp and hot according to Eradicates
Cold, lively atmosphere blood, clearing heat and detoxicating Chinese medicine theory, are combined using Chinese herbal medicine, have studied a kind of external used medicine for curing onychomycosis
And its preparation method of drug.The drug that the present invention cures onychomycosis is liquid, and directly spray is put on outside patient's lesion, can reach
Non-stimulated, without side-effects, penetration is strong, does not influence patient's normal life and work, effect curative for effect.
A kind of external used medicine for the treatment of onychomycosis proposed by the invention, is made of following traditional Chinese medicinal components and parts by weight：It is bitter
24.5~26 parts of ginseng, 26-28.5 parts windproof, 15~18 parts of the tuber of stemona, 21~29 parts of Cortex Phellodendri, 16~25 parts of frutus cnidii, climbing groundsel 19
~22 parts, 12~18 parts of honeysuckle, 9~12 parts of Fructus Forsythiae, 16~20 parts of corter pseudolaricis, 21~29 parts of dandelion, favus skin 18~26
Part, 19~25 parts of the fruit of summer cypress, 10~15 parts of camphor.
Preferably, the external used medicine of a kind for the treatment of onychomycosis, is made of following traditional Chinese medicinal components and parts by weight：
24.5 parts of kuh-seng, 21 parts of Cortex Phellodendri, 16 parts of frutus cnidii, 19 parts of climbing groundsel, 12 parts of honeysuckle, connects 26 parts windproof, 15 parts of the tuber of stemona
Stick up 9 parts, 16 parts of corter pseudolaricis, 21 parts of dandelion, 18 parts of favus skin, 19 parts of the fruit of summer cypress, 10 parts of camphor.
It is further preferred that a kind of external used medicine for the treatment of onychomycosis, by following traditional Chinese medicinal components and parts by weight system
At：
25 parts of kuh-seng, 26 parts of Cortex Phellodendri, 20 parts of frutus cnidii, 21.5 parts of climbing groundsel, 15 parts of honeysuckle, connects 27 parts windproof, 16 parts of the tuber of stemona
Stick up 11 parts, 18 parts of corter pseudolaricis, 25 parts of dandelion, 26 parts of favus skin, 22.5 parts of the fruit of summer cypress, 12 parts of camphor.
Still further preferably, the external used medicine of a kind for the treatment of onychomycosis, by following traditional Chinese medicinal components and parts by weight
It is made：
26 parts of kuh-seng, 29 parts of Cortex Phellodendri, 25 parts of frutus cnidii, 22 parts of climbing groundsel, 18 parts of honeysuckle, connects 28.5 parts windproof, 18 parts of the tuber of stemona
Stick up 12 parts, 20 parts of corter pseudolaricis, 29 parts of dandelion, 26 parts of favus skin, 25 parts of the fruit of summer cypress, 15 parts of camphor.
Steps are as follows for a kind of preparation method of the external used medicine of above-mentioned treatment onychomycosis：
1, by kuh-seng, the windproof, tuber of stemona, Cortex Phellodendri, frutus cnidii, climbing groundsel, honeysuckle, Fructus Forsythiae, corter pseudolaricis, the Pu Gong in raw medicinal material
English, favus skin, the fruit of summer cypress clean chopping mixing and are placed into boiling pot, and softening water immersion drug, soaking time 60 minutes is added；
2, boiling pot is heated to boiling using decocting method, boiling time was controlled at 20~30 minutes, stopped heating, cooling；
3, liquid after cooling is put into holding vessel, material-compound tank is squeezed into filter；
4, take camphor, smash to pieces smash it is spare；
5, camphor powder is added in material-compound tank, through feeding pump after stirring evenly, filter squeezes into temporary storage tank, then through complete
Automatic filling machine is once filled into the spray bottle sterilized.
The present invention has the advantages that：
A kind of external used medicine for curing onychomycosis of the present invention is formulated by 13 kinds of herbal raw materials, will due to using
The directly spray of prepared liquid Chinese medicine is put on the affected area of patient, can Eradicates is damp and hot, lively atmosphere blood, dispersing wind and cold, clearing heat and detoxicating.Reduce
The irritation of adverse reaction and endo-medicine and Western medicine paint caused by endo-medicine are brought not to the life of patient
Just.The directly spray of the external application Chinese medicine of the present invention is put on the affected area of patient, and easy to use, penetration is strong, has no toxic side effect, and has
Notable curative effect.Selected Chinese medicinal material can be directly from market purchasing in the present invention, and preparation method is simple, at low cost, easily
It promotes.
Specific implementation mode
The present invention is explained further below by specific embodiment, the open purpose of the present invention is intended to the protection scope of the invention
All interior changes and improvements, the invention is not limited in embodiment described below.
A kind of external used medicine for the treatment of onychomycosis proposed by the invention is mainly according to eliminating dampness heat-clearing, invigorate blood circulation, resists
The drug action mechanism of bacterium anti-inflammatory, clearing away heat to and alleviating pain, using kuh-seng, the windproof, tuber of stemona, Cortex Phellodendri, frutus cnidii, climbing groundsel, honeysuckle, Fructus Forsythiae,
Corter pseudolaricis, dandelion, favus skin, the fruit of summer cypress, the combination of 13 taste Chinese medicine material of camphor are made.The pharmacology of 13 taste Chinese herbal medicines in the present invention
It is：
Kuh-seng：Bitter is cold in nature, antibacterial anti-inflammatory；
It is windproof：Acrid-sweet flavor, property is micro- wet, there is dispersing wind and cold dehumidifying；
The tuber of stemona：Sweet-bitter flavor, property is micro- wet, moistens the lung and relieve the cough, desinsection；
Cortex Phellodendri：Bitter, it is cold in nature, it is damp and hot there are nourishing yin and lessening fire, Eradicates；
Frutus cnidii：Acrid flavour is bitter, warm-natured, there is warm kidney, supporing yang, evacuate pathogenic wind eliminating dampness, desinsection；
Climbing groundsel：It clears liver and improve vision, remuval of damp and hot, control sore；
Honeysuckle：It is sweet in flavor, it is cold in nature, have effects that clearing heat and detoxicating, wind-dispelling heat-dissipating；
Fructus Forsythiae：Sweet in flavor, cold nature can clearing heat, releasing toxin, removing swelling；
Corter pseudolaricis：Sweet in flavor, cold nature plays the role of heat-clearing, desinsection, antipruritic；
Dandelion：It is mild-natured, sweet and slightly bitter taste, clearing heat and detoxicating, dispersing swelling and dissipating binds；
Favus skin：Bitter, cold in nature, heat-clearing solution is wet；
The fruit of summer cypress：Sweet-bitter flavor, cold in nature, clearing away damp-heat；
Camphor：Property heat, acrid flavour enters the heart, the spleen channel, function is sensible, desinsection, except analgesic of itching.
The invention is realized in this way：
A kind of external used medicine for curing onychomycosis, traditional Chinese medicinal components and parts by weight are as follows：
24.5~26 parts of kuh-seng, 26-28.5 parts windproof, 15~18 parts of the tuber of stemona, 21~29 parts of Cortex Phellodendri, 16~25 parts of frutus cnidii, thousand
In 19~22 parts of light, 12~18 parts of honeysuckle, 9~12 parts of Fructus Forsythiae, 16~20 parts of corter pseudolaricis, 21~29 parts of dandelion, favus skin
18~26 parts, 19~25 parts of the fruit of summer cypress, 10~15 parts of camphor.
Prescription 1：24.5 parts of kuh-seng, 26 parts windproof, 15 parts of the tuber of stemona, 21 parts of Cortex Phellodendri, 16 parts of frutus cnidii, 19 parts of climbing groundsel, gold
12 parts of honeysuckle flower, 9 parts of Fructus Forsythiae, 16 parts of corter pseudolaricis, 21 parts of dandelion, 18 parts of favus skin, 19 parts of the fruit of summer cypress, 10 parts of camphor.
Prescription 2：25 parts of kuh-seng, 27 parts windproof, 16 parts of the tuber of stemona, 26 parts of Cortex Phellodendri, 20 parts of frutus cnidii, 21.5 parts of climbing groundsel, gold
15 parts of honeysuckle flower, 11 parts of Fructus Forsythiae, 18 parts of corter pseudolaricis, 25 parts of dandelion, 26 parts of favus skin, 22.5 parts of the fruit of summer cypress, 12 parts of camphor.
Prescription 3：26 parts of kuh-seng, 28.5 parts windproof, 18 parts of the tuber of stemona, 29 parts of Cortex Phellodendri, 25 parts of frutus cnidii, 22 parts of climbing groundsel, gold
18 parts of honeysuckle flower, 12 parts of Fructus Forsythiae, 20 parts of corter pseudolaricis, 29 parts of dandelion, 26 parts of favus skin, 25 parts of the fruit of summer cypress, 15 parts of camphor.
A kind of above-mentioned treatment onychomycosis by described in traditional Chinese medicinal components of the present invention and parts by weight and prescription 1, prescription 2, prescription 3
Steps are as follows for the preparation method of external used medicine：
1, by kuh-seng, the windproof, tuber of stemona, Cortex Phellodendri, frutus cnidii, climbing groundsel, honeysuckle, Fructus Forsythiae, corter pseudolaricis, the Pu Gong in raw medicinal material
English, favus skin, the fruit of summer cypress clean chopping mixing and are placed into boiling pot, and softening water immersion drug, soaking time 60 minutes is added；
2, boiling pot is heated to boiling using decocting method, boiling time was controlled at 20~30 minutes, stopped heating, cooling；
3, liquid after cooling is put into holding vessel, material-compound tank is squeezed into filter；
4, take camphor, smash to pieces smash it is spare；
5, camphor powder is added in material-compound tank, through feeding pump after stirring evenly, filter squeezes into temporary storage tank, then through complete
Automatic filling machine is once filled into the spray bottle sterilized.
A kind of external used medicine and preparation method thereof for the treatment of onychomycosis of the present invention, over the course for the treatment of directly sprays drug
It is put on the affected area of patient, or the entire finger smeared and suffer from first is dipped with cotton swab, daily 4 to 6 times, natural air drying does not dial first, no
Wrapping.Easy to use, the penetration of drug is strong, nonirritant, has no toxic side effect, can Eradicates is damp and hot, lively atmosphere blood, dispersing wind and cold, clear
Thermal detoxification.Reduce oral drugs to bring not the stimulation of human body and other drug responses or Western medicine paint to minimal invasive treatment
Just.It forms the herbal raw material buying of drug conveniently, and manufacturing process is simple, at low cost, easily promotes.The treatment ash of the present invention refers to
The drug of first has obvious curative effects.
Claims (5)
1. a kind of external used medicine for curing onychomycosis, it is characterized in that：The external used medicine of the treatment onychomycosis is by kuh-seng, prevents
In wind, the tuber of stemona, Cortex Phellodendri, frutus cnidii, climbing groundsel, honeysuckle, Fructus Forsythiae, corter pseudolaricis, dandelion, favus skin, the fruit of summer cypress, 13 taste of camphor
Herbal raw material is made；Wherein traditional Chinese medicinal components and parts by weight are as follows：24.5~26 parts of kuh-seng, the 26-28.5 parts windproof, tuber of stemona 15~18
Part, 21~29 parts of Cortex Phellodendri, 16~25 parts of frutus cnidii, 19~22 parts of climbing groundsel, 12~18 parts of honeysuckle, 9~12 parts of Fructus Forsythiae, the native rose of Sharon
16~20 parts of skin, 21~29 parts of dandelion, 18~26 parts of favus skin, 19~25 parts of the fruit of summer cypress, 10~15 parts of camphor.
2. a kind of external used medicine for curing onychomycosis according to claim 1, it is characterized in that：The treatment onychomycosis
External used medicine is made of the Chinese medicine of following traditional Chinese medicinal components and parts by weight：24.5 parts of kuh-seng, 26 parts windproof, 15 parts of the tuber of stemona, Cortex Phellodendri 21
Part, 16 parts of frutus cnidii, 19 parts of climbing groundsel, 12 parts of honeysuckle, 9 parts of Fructus Forsythiae, 16 parts of corter pseudolaricis, 21 parts of dandelion, 18 parts of favus skin,
19 parts of the fruit of summer cypress, 10 parts of camphor.
3. a kind of external used medicine for curing onychomycosis according to claim 1, it is characterized in that：The treatment onychomycosis
External used medicine is made of the Chinese medicine of following traditional Chinese medicinal components and parts by weight：25 parts of kuh-seng, 27 parts windproof, 16 parts of the tuber of stemona, 26 parts of Cortex Phellodendri,
20 parts of frutus cnidii, 21.5 parts of climbing groundsel, 15 parts of honeysuckle, 11 parts of Fructus Forsythiae, 18 parts of corter pseudolaricis, 25 parts of dandelion, 26 parts of favus skin,
22.5 parts of the fruit of summer cypress, 12 parts of camphor.
4. a kind of external used medicine for curing onychomycosis according to claim 1, it is characterized in that：The treatment onychomycosis
External used medicine is made of the Chinese medicine of following traditional Chinese medicinal components and parts by weight：
26 parts of kuh-seng, 29 parts of Cortex Phellodendri, 25 parts of frutus cnidii, 22 parts of climbing groundsel, 18 parts of honeysuckle, connects 28.5 parts windproof, 18 parts of the tuber of stemona
Stick up 12 parts, 20 parts of corter pseudolaricis, 29 parts of dandelion, 26 parts of favus skin, 25 parts of the fruit of summer cypress, 15 parts of camphor.
5. a kind of preparation method for preparing Claims 1 to 4 any one of them and curing the external used medicine of onychomycosis, step is such as
Under：
1）By kuh-seng, the windproof, tuber of stemona, Cortex Phellodendri, frutus cnidii, climbing groundsel, honeysuckle, Fructus Forsythiae, corter pseudolaricis, the Pu Gong in raw medicinal material
English, favus skin, the fruit of summer cypress clean chopping mixing and are placed into boiling pot, and softening water immersion drug, soaking time 60 minutes is added；
2）Boiling pot is heated to boiling using decocting method, boiling time was controlled at 20~30 minutes, stopped heating, cooling；
3）Liquid after cooling is put into holding vessel, material-compound tank is squeezed into filter；
4）Take camphor, smash to pieces smash it is spare；
5）Camphor powder is added in material-compound tank, through feeding pump after stirring evenly, filter squeezes into temporary storage tank, then through complete
Automatic filling machine is once filled into the spray bottle sterilized.
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Cited By (1)
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| CN111888439A (en) * | 2020-08-06 | 2020-11-06 | 湖南巨禧医药科技有限公司 | Medicament for treating onychomycosis and preparation method thereof |
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Application publication date: 20181106 |