CN105963664A - Plaster composition capable of diminishing inflammation and relieving pain and plaster - Google Patents
Plaster composition capable of diminishing inflammation and relieving pain and plaster Download PDFInfo
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- CN105963664A CN105963664A CN201610489634.7A CN201610489634A CN105963664A CN 105963664 A CN105963664 A CN 105963664A CN 201610489634 A CN201610489634 A CN 201610489634A CN 105963664 A CN105963664 A CN 105963664A
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
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- A61N2005/066—Radiation therapy using light characterised by the wavelength of light used infrared far infrared
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Abstract
The invention discloses a plaster capable of diminishing inflammation and relieving pain and a preparation method thereof. The plaster structurally comprises a lining material, a plaster layer and a plaster covering and is characterized in that the plaster layer comprises, by weight percentage, 20-35% of traditional Chinese medicine materials, 40-50% of natural adhesive and 15-25% of far infrared ceramic powder. The plaster has the advantages that the medicinal components of the plaster can be effectively absorbed by a user in a short time to act on affected parts by the far infrared rays of the far infrared ceramic powder and the heat generation effect of the far infrared rays, symptoms can be relieved fast, and the plaster can effectively treat rheumatalgia, joint pain, neuralgia, headache, sprain, muscular soreness and the like and is safe to use, non-irritant, quick in action, lasting in effect and free of toxic and side effect.
Description
Technical Field
The invention belongs to the field of traditional Chinese medicines, and particularly relates to an anti-inflammatory analgesic plaster composition and a plaster.
Background
Pain diseases caused by joint, rheumatism, nerve, sprain, muscular soreness and the like are mainly manifested by joint pain, local swelling, numbness, muscular soreness and the like, even the function is limited, and serious patients influence the normal work and life of people. Currently, the treatment for the diseases comprises drug therapy and physical therapy, wherein the drug therapy comprises oral preparations, injections, Chinese traditional medicine plasters and the like, but the following problems are generally existed: (1) oral formulations and injections: the long-term use of the traditional Chinese medicine composition can easily cause toxic and side effects of internal organs, so as to cause new diseases, and bring more pain and trouble to patients; (2) the existing Chinese patent medicine plaster comprises the following components: firstly, the formula basically contains chemical drugs, so that the skin is easy to be stimulated to cause skin lesion after long-term use, and some can cause other lesions of the body; secondly, the existing plaster products are slowly absorbed through skin, the medicine has poor effect, the curative effect is not obvious, and the like; (3) physical therapy: the existing physical therapy such as massage, physical therapy and the like only can relieve symptoms, but cannot achieve the purpose of treating the root cause.
There are also some plaster products in the prior art, such as: chinese patent documents CN103566343A disclose pain-relieving plaster, CN101138626 bone-penetrating pain-relieving plaster and the like, but plaster products prepared by using star anise, rhizoma kaempferiae, angelica dahurica, rhizoma atractylodis, angelica, dried ginger, radix aconiti agrestis, rhizoma ligustici wallichii and other raw medicinal materials and far infrared ceramic powder are not reported.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides an anti-inflammatory analgesic plaster composition and a plaster, and also provides a preparation method of the composition and the plaster.
Summary of the invention:
the plaster formula raw materials of the invention contain traditional Chinese medicinal materials, natural adhesive and far infrared ceramic powder; the medicines are used together to play the roles of dispelling wind and eliminating dampness, warming channels and relieving pain, warming middle-jiao and dispelling cold, regulating qi to alleviate pain, promoting blood circulation and invigorating pulse, eliminating dampness and strengthening spleen, dispelling wind, inducing resuscitation and inducing resuscitation, drawing out toxin and expelling pus, promoting granulation and relieving pain, restoring yang and invigorating pulse, inducing diuresis and reducing edema, cooling and relieving itching and the like. The formula of the invention can effectively absorb the medicinal components in a short time and directly act on diseases through the far infrared rays of the far infrared ceramic powder and the heating effect thereof, so that the disease symptoms can be quickly relieved.
The technical scheme of the invention is as follows:
an anti-inflammatory and analgesic plaster composition comprises traditional Chinese medicinal materials, a natural adhesive and far infrared ceramic powder, wherein the plaster layer comprises the following components in percentage by weight: 20-35%, 40-50% and 15-25%.
According to the invention, preferably, the Chinese medicinal materials comprise star anise, rhizoma kaempferiae, radix angelicae, rhizoma atractylodis, angelica sinensis, rhizoma zingiberis, radix aconiti agrestis, ligusticum wallichii, menthol, borneol and camphor; the natural adhesive comprises natural rubber, rosin, vaseline, liquid paraffin and lanolin.
The invention provides the following preferred technical scheme:
an anti-inflammatory analgesic plaster composition comprises the following raw materials in parts by mass:
2-6 parts of star anise, 3-10 parts of rhizoma kaempferiae, 5-10 parts of angelica dahurica, 10-15 parts of rhizoma atractylodis, 10-15 parts of angelica, 10-20 parts of dried ginger, 5-10 parts of monkshood, 5-10 parts of kusnezoff monkshood root, 5-10 parts of ligusticum wallichii, 6-12 parts of menthol, 5-10 parts of borneol, 5-10 parts of camphor, 70-100 parts of natural rubber, 30-50 parts of rosin, 6-12 parts of vaseline, 1-5 parts of liquid paraffin, 5-10 parts of wool fat and 50-80 parts of far infrared ceramic powder.
According to the invention, it is further preferred that:
an anti-inflammatory analgesic plaster composition comprises the following raw materials in parts by mass:
4 parts of star anise, 5 parts of rhizoma kaempferiae, 8 parts of angelica dahurica, 12 parts of rhizoma atractylodis, 12 parts of angelica, 17 parts of rhizoma zingiberis, 6 parts of radix aconiti agrestis, 6 parts of ligusticum wallichii, 9 parts of menthol, 7 parts of borneol, 7 parts of camphor, 95 parts of natural rubber, 40 parts of rosin, 9 parts of vaseline, 3.5 parts of liquid paraffin, 7.5 parts of lanolin and 65 parts of far infrared ceramic powder;
or,
2 parts of star anise, 10 parts of rhizoma kaempferiae, 5 parts of angelica dahurica, 15 parts of rhizoma atractylodis, 10 parts of angelica, 20 parts of rhizoma zingiberis, 5 parts of radix aconiti, 10 parts of radix aconiti agrestis, 5 parts of ligusticum wallichii, 12 parts of menthol, 5 parts of borneol, 10 parts of camphor, 70 parts of natural rubber, 50 parts of rosin, 6 parts of vaseline, 5 parts of liquid paraffin, 5 parts of lanolin and 80 parts of far infrared ceramic powder;
or,
6 parts of star anise, 3 parts of rhizoma kaempferiae, 10 parts of angelica dahurica, 10 parts of rhizoma atractylodis, 15 parts of angelica, 10 parts of rhizoma zingiberis, 10 parts of radix aconiti, 5 parts of radix aconiti agrestis, 10 parts of ligusticum wallichii, 6 parts of menthol, 10 parts of borneol, 5 parts of camphor, 100 parts of natural rubber, 30 parts of rosin, 12 parts of vaseline, 1 part of liquid paraffin, 10 parts of wool grease and 50 parts of far infrared ceramic powder.
The raw materials of the invention are all conventional commercial products without special indication.
A preparation method of an anti-inflammatory analgesic plaster composition comprises the following steps:
(1) taking the aniseed, the rhizoma kaempferiae, the angelica dahurica, the rhizoma atractylodis, the angelica, the rhizoma zingiberis, the radix aconiti agrestis and the rhizoma ligustici wallichii with the formula amount, and processing the mixture into tablets or coarse powder;
(2) putting the raw material slices or coarse powder prepared in the step (1) into an extraction tank, and adding ethanol to soak for 10-16 hours;
(3) heating the soaked materials in an extraction tank to slightly boil for 1-3 hr, stopping heating, and recovering the extractive solution;
(4) adding ethanol into the raw materials extracted for the first time in the step (3), heating to slightly boil for 1-3 hours, stopping heating, and recovering the extracting solution;
(5) adding ethanol into the raw materials extracted for the second time in the step (4), heating to slightly boil for 1-3 hours, stopping heating, and recovering the extracting solution;
(6) mixing the extractive solutions obtained by the three-time heating extraction, heating and concentrating to obtain soft extract with relative density of 1.2-1.3 at 50 deg.C, cooling, filtering, and placing into a sealed container;
(7) adding the thick paste extracted in the step (6) into menthol, borneol, camphor, natural rubber, rosin, vaseline, liquid paraffin, lanolin and far infrared ceramic powder according to the formula amount, and stirring until the added materials are uniformly mixed to form the anti-inflammatory analgesic ointment composition.
Preferably, the soaking time in step (2) is 12 hours.
According to the present invention, it is preferable that the heating in the steps (3), (4) and (5) is stopped after the heating is carried out to a slight boiling temperature for 2 hours.
According to the invention, preferably, in the step (6), the mixed solution is heated and concentrated to be thick paste with the relative density of 1.25 at 50 ℃.
The structure of the anti-inflammatory analgesic plaster consists of a backing material, a plaster layer and a plaster surface covering, and is characterized in that: the plaster layer is the anti-inflammatory analgesic plaster composition.
According to the invention, the backing material can be cloth material or paper lining material according to the prior art; the plaster surface covering is release paper or release film.
The preparation method of the anti-inflammatory analgesic plaster comprises the steps of uniformly spreading the anti-inflammatory analgesic plaster composition on a backing material, covering release paper or release film, slitting, inspecting and packaging.
Pharmacological analysis:
anise: [ CHARACTERISTICS AND WEI GUI JING ] is pungent and warm. It enters liver, kidney, spleen and stomach meridians. [ FUNCTIONS AND INDICATIONS ] can warm yang, dispel cold, regulate qi-flowing, and alleviate pain. Can be used for treating cold hernia with abdominal pain, lumbago due to kidney deficiency, stomach cold with emesis, and abdominal cold pain.
And (3) rhizoma kaempferiae: [ CHARACTERISTICS AND WEI GUI JING ] is pungent and warm. It enters stomach meridian. [ FUNCTIONS AND INDICATIONS ] can promote the circulation of qi, warm the middle energizer, promote digestion, and alleviate pain. Can be used for treating fullness and distention of chest and diaphragm, abdominal psychroalgia, and indigestion.
Radix angelicae: [ CHARACTERISTICS AND WEI GUI JING ] is pungent and warm. It enters stomach, large intestine and lung meridians. [ FUNCTIONS AND INDICATIONS ] can relieve exterior syndrome, dispel cold, dispel wind, alleviate pain, dredge nasal orifice, eliminate dampness, stop leukorrhagia, and relieve swelling and pus. It can be used for treating headache, supercilium pain, nasal obstruction, nasal discharge, allergic rhinitis, nasosinusitis, toothache, leukorrhagia, and pyocutaneous disease with swelling and pain.
Rhizoma atractylodis: [ PROPERTIES AND WEIGHT GUIDING GEN ] is pungent, bitter and warm. It enters spleen, stomach and liver meridians. [ FUNCTIONS AND INDICATIONS ] can eliminate dampness, invigorate the spleen, expel wind and remove cold, and improve eyesight. Can be used for warming middle warmer, abdominal distention, diarrhea, edema, tinea pedis atrophy 36484, rheumatic arthralgia, wind cold type stomach, night blindness, dim eyesight, and astringency.
Chinese angelica: [ PROPERTIES AND WEIGHT GUIDING GEN ] is sweet, pungent and warm. [ FUNCTIONS AND INDICATIONS ] can tonify blood, activate blood, regulate menstruation, relieve pain, moisten intestines and relieve constipation. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, rheumatalgia, traumatic injury, superficial infection, pyocutaneous disease, intestinal dryness, and constipation. The wine angelica sinensis can activate blood and promote menstruation. Can be used for treating amenorrhea, dysmenorrhea, rheumatalgia, and traumatic injury.
Dried ginger: [ CHARACTER, WEI AND GUIJING ] is pungent and hot. It enters spleen, stomach, kidney, heart and lung meridians. [ FUNCTIONS AND INDICATIONS ] can warm the middle-jiao to dispel cold, restore yang to activate collaterals, warm the lung and resolve retained fluid. Can be used for treating abdominal psychroalgia, emesis, diarrhea, cold limbs, slight pulse, cough and asthma due to cold fluid retention.
Radix aconiti: [ PROPERTIES AND DENTAL GUIDANCE ] is pungent, bitter and hot; it enters heart, liver, kidney and spleen meridians. [ FUNCTIONS AND INDICATIONS ] can dispel wind, remove dampness, warm meridians, and alleviate pain. Can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, cold hernia pain, and anesthesia and pain relieving.
Kusnezoff monkshood root: [ PROPERTIES AND DENTAL GUIDANCE ] is pungent, bitter and hot; it enters heart, liver, kidney and spleen meridians. [ FUNCTIONS AND INDICATIONS ] can dispel wind, remove dampness, warm meridians, and alleviate pain. Can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, cold hernia pain, and anesthesia and pain relieving.
Ligusticum wallichii: [ PROPERTIES, WESTERN AND CHANNEL GUIDING ], and [ FUNCTION AND INDICATION ]
Menthol: [ FUNCTIONS AND INDICATIONS ] has the functions of stimulating skin mucosa, relieving itching, diminishing inflammation, relieving pain, and cooling local parts. It is used clinically in treating pain, inflammation and swelling.
Borneol: [ PROPERTIES AND WEIGHT GUIDING CHANNEL ] is pungent, bitter and slightly cold. It enters heart, spleen and lung meridians. [ FUNCTIONS AND INDICATIONS ] can induce resuscitation, refresh mind, clear heat and alleviate pain. Can be used for treating fever unconsciousness, convulsion, apoplexy, phlegm syncope, coma, thoracic obstruction, cardiodynia, conjunctival congestion, aphtha, sore throat, and purulence in ear canal.
Camphor: [ FUNCTIONS AND INDICATIONS ] can dredge meridians; promoting qi stagnation; removing dirt; killing parasites and relieving itching; relieving swelling and pain. The camphor has mild stimulation and antisepsis effects on skin, and has effects of dispelling pathogenic wind and eliminating phlegm on central nervous system, circulatory system and oral camphor (edible).
The formula of the invention accords with the compatibility of monarch, minister, assistant and guide medicines, the medicines are combined, and the effects of dispelling wind and eliminating dampness, warming channels and relieving pain, warming middle-jiao and dispelling cold, regulating qi and relieving pain, enriching and activating blood, eliminating dampness and strengthening spleen, dispelling wind, inducing resuscitation and inducing resuscitation, drawing out pus and expelling pus, promoting granulation and relieving pain, restoring yang and invigorating pulse, inducing diuresis and relieving swelling, cooling and relieving itching and the like are exerted.
The invention has the following beneficial effects:
(1) all materials selected by the formula are pure natural materials, do not contain irritant chemical components, are safe to use, do not irritate the skin, and have no toxic or side effect.
(2) The formula of the invention contains far infrared ceramic powder known in the prior art, the material can release far infrared rays with the wavelength of 4-14 microns, after the far infrared rays act on the skin, most of energy is absorbed by the skin, the absorbed energy is converted into heat energy to cause the skin temperature to rise, a heat sensor in the skin is stimulated, blood vessels are expanded through the reflection of thalamus, the blood circulation is accelerated, and the blood circulation is improved; increasing cell activity, enhancing immunity, promoting metabolism, relieving inflammation, inhibiting bacteria, and removing toxin. The far infrared ceramic material can effectively improve the physique of a human body and has the functions of disease prevention and physical therapy.
(3) The far infrared ceramic powder has the advantages that the far infrared rays of the far infrared ceramic powder and the heating effect of the far infrared ceramic powder open pores of skin, full absorption of natural medicine components in the formula is promoted to a great extent, the medicine components effectively absorb the medicine components in a short time and then directly act on diseases, so that diseases are relieved, treated and cleared away quickly, the patients are prevented from suffering from pains after long-term administration and being afflicted by double layers of medicines, and the toxic and side effects caused by long-term administration are further avoided.
Detailed Description
The present invention will be further described with reference to the following specific examples. It is to be understood that the following examples are illustrative of the present invention only and are not intended to limit the scope of the present invention.
Description of raw materials and auxiliary materials in the examples:
example 1: preparation of antiphlogistic and analgesic plaster composition
An anti-inflammatory analgesic plaster composition is prepared from the following raw materials in parts by mass:
4 parts of star anise, 5 parts of rhizoma kaempferiae, 8 parts of angelica dahurica, 12 parts of rhizoma atractylodis, 12 parts of angelica, 17 parts of rhizoma zingiberis, 6 parts of radix aconiti agrestis, 6 parts of ligusticum wallichii, 9 parts of menthol, 7 parts of borneol, 7 parts of camphor, 95 parts of natural rubber, 40 parts of rosin, 9 parts of vaseline, 3.5 parts of liquid paraffin, 7.5 parts of lanolin and 65 parts of far infrared ceramic powder;
the preparation method comprises the following steps:
(1) taking the aniseed, the rhizoma kaempferiae, the angelica dahurica, the rhizoma atractylodis, the angelica, the rhizoma zingiberis, the radix aconiti agrestis and the rhizoma ligustici wallichii with the formula amount, and processing the mixture into tablets or coarse powder;
(2) putting the raw material slices or coarse powder prepared in the step (1) into an extraction tank, and adding ethanol to soak for 12 hours;
(3) heating the soaked raw materials in an extraction tank to slightly boil for 2 hours, stopping heating, and recovering the extracting solution;
(4) adding ethanol into the raw materials extracted for the first time in the step (3), heating to slightly boil for 2 hours, stopping heating, and recovering the extracting solution;
(5) adding ethanol into the raw materials extracted for the second time in the step (4), heating to slightly boil for 2 hours, stopping heating, and recovering the extracting solution;
(6) mixing the extractive solutions obtained by the three-time heating extraction and recovery, heating and concentrating to obtain soft extract with relative density of 1.25 at 50 deg.C, cooling, filtering, and placing the soft extract into a sealed container;
(7) adding the thick paste extracted in the step (6) into menthol, borneol, camphor, natural rubber, rosin, vaseline, liquid paraffin, lanolin and far infrared ceramic powder according to the formula amount, and stirring until the added materials are uniformly mixed to form the anti-inflammatory analgesic plaster composition.
Example 2: preparation of antiphlogistic and analgesic plaster composition
An anti-inflammatory analgesic plaster composition is prepared from the following raw materials in parts by mass:
2 parts of star anise, 10 parts of rhizoma kaempferiae, 5 parts of angelica dahurica, 15 parts of rhizoma atractylodis, 10 parts of angelica, 20 parts of rhizoma zingiberis, 5 parts of radix aconiti, 10 parts of radix aconiti agrestis, 5 parts of ligusticum wallichii, 12 parts of menthol, 5 parts of borneol, 10 parts of camphor, 70 parts of natural rubber, 50 parts of rosin, 6 parts of vaseline, 5 parts of liquid paraffin, 5 parts of lanolin and 80 parts of far infrared ceramic powder;
the preparation method comprises the following steps:
(1) taking the aniseed, the rhizoma kaempferiae, the angelica dahurica, the rhizoma atractylodis, the angelica, the rhizoma zingiberis, the radix aconiti agrestis and the rhizoma ligustici wallichii with the formula amount, and processing the mixture into tablets or coarse powder;
(2) putting the raw material slices or coarse powder prepared in the step (1) into an extraction tank, and adding ethanol to soak for 10 hours;
(3) heating the soaked materials in an extraction tank to slightly boil for 1-3 hr, stopping heating, and recovering the extractive solution;
(4) adding ethanol into the raw materials extracted for the first time in the step (3), heating to slightly boil for 1 hour, stopping heating, and recovering the extracting solution;
(5) adding ethanol into the raw materials extracted for the second time in the step (4), heating to slightly boil for 1 hour, stopping heating, and recovering the extracting solution;
(6) mixing the extractive solutions obtained by the three-time heating extraction and recovery, heating and concentrating to obtain soft extract with relative density of 1.2 at 50 deg.C, cooling, filtering, and placing the soft extract into a sealed container;
(7) adding the thick paste extracted in the step (6) into menthol, borneol, camphor, natural rubber, rosin, vaseline, liquid paraffin, lanolin and far infrared ceramic powder according to the formula amount, and stirring until the added materials are uniformly mixed to form the anti-inflammatory analgesic plaster composition.
Example 3: preparation of anti-inflammatory analgesic plaster
The anti-inflammatory analgesic plaster structurally comprises a backing material, a plaster layer and a plaster surface covering, wherein the plaster layer is prepared from the following raw materials in parts by mass:
6 parts of star anise, 3 parts of rhizoma kaempferiae, 10 parts of angelica dahurica, 10 parts of rhizoma atractylodis, 15 parts of angelica, 10 parts of rhizoma zingiberis, 10 parts of radix aconiti, 5 parts of radix aconiti agrestis, 10 parts of ligusticum wallichii, 6 parts of menthol, 10 parts of borneol, 5 parts of camphor, 100 parts of natural rubber, 30 parts of rosin, 12 parts of vaseline, 1 part of liquid paraffin, 10 parts of wool grease and 50 parts of far infrared ceramic powder.
The preparation method comprises the following steps: the anti-inflammatory analgesic plaster composition is prepared by the method of example 1, the anti-inflammatory analgesic plaster composition is evenly spread on a backing material, and is covered with release paper or release film, and the anti-inflammatory analgesic plaster composition is obtained after cutting, checking and packaging.
Example 4: clinical experiments
(1) Selected cases are tested by patients with restricted functions such as rheumatalgia, arthralgia, neuralgia, headache, sprain, muscular soreness and the like:
(2) the evaluation standard of curative effect is as follows:
and (3) curing: the disease and the syndrome disappear completely, and the life is normal;
the method has the following advantages: the symptoms are obviously improved, and the pain symptoms are relieved;
and (4) invalidation: there was no improvement, even an exacerbation of symptoms;
(3) the following are the records of clinical use of 60 patients aged 25-70 years, wherein 21 patients suffering from rheumatic knee joint pain, 6 patients suffering from shoulder pain, 6 patients suffering from cervical pain, 9 patients suffering from neuropathic headache, 9 patients suffering from sprain and 9 patients suffering from muscular soreness, the plaster composition prepared in example 1 is further prepared into a plaster product to be directly pasted on a pain part, and 6 days are a treatment course. The pain of a general patient is relieved after the traditional Chinese medicine is used for 2 days, the pain is obviously relieved after 1 course of treatment, the symptoms completely disappear after 3 courses of treatment, and the symptoms disappear after 5 courses of treatment for a patient with serious illness; specific test data are shown in table 1 below:
TABLE 1 results of clinical trials
Example 5: experiment of drug effect
The plaster compositions prepared in examples 1 and 2 were further prepared into plaster products, and the plaster prepared in example 3 was compared with commercially available conventional anti-inflammatory and analgesic plasters (WS 3-B-1614-93, eighth volume of pharmaceutical Standard Chinese medicinal formulation preparation of Ministry of public health of the people's republic of China) for clinical efficacy, and the results are shown in Table 2. Research results show that compared with the traditional inflammation-diminishing and pain-relieving paste, the far infrared ceramic material is contained in the formula, the far infrared ceramic material can release far infrared rays with the wavelength of 4-14 microns, most of energy is absorbed by skin after the far infrared rays act on the skin, the absorbed energy is converted into heat energy, pores of the skin are opened, full absorption of natural medicine ingredients in the formula is improved to a great extent, the medicine ingredients effectively absorb the far infrared ceramic material in a short time and then directly act on diseases, the symptoms are quickly relieved, and the lasting time is long.
TABLE 2 comparison of the results of the experiments
| Plaster | Onset time | Duration of action |
| Reference (traditional plaster) | 25±2h | 24±2h |
| Example 1 | 20±3h | 41±2h |
| Example 2 | 21±2h | 41±2h |
| Example 3 | 22±2h | 40±2h |
Claims (10)
1. An anti-inflammatory analgesic plaster composition is characterized by comprising traditional Chinese medicinal materials, a natural adhesive and far infrared ceramic powder, wherein the weight percentages of the traditional Chinese medicinal materials, the natural adhesive and the far infrared ceramic powder are as follows: 20-35%, 40-50% and 15-25%.
2. An anti-inflammatory analgesic plaster composition as claimed in claim 1, wherein: the Chinese medicinal materials include fructus Anisi Stellati, rhizoma Kaempferiae, radix Angelicae Dahuricae, rhizoma Atractylodis, radix Angelicae sinensis, Zingiberis rhizoma, radix Aconiti Kusnezoffii, rhizoma Ligustici Chuanxiong, Mentholum, Borneolum Syntheticum, and Camphora; the natural adhesive comprises natural rubber, rosin, vaseline, liquid paraffin and lanolin.
3. An anti-inflammatory analgesic plaster composition as claimed in claim 1 or 2, characterized in that: the composite material comprises the following raw materials in parts by mass:
2-6 parts of star anise, 3-10 parts of rhizoma kaempferiae, 5-10 parts of angelica dahurica, 10-15 parts of rhizoma atractylodis, 10-15 parts of angelica, 10-20 parts of dried ginger, 5-10 parts of monkshood, 5-10 parts of kusnezoff monkshood root, 5-10 parts of ligusticum wallichii, 6-12 parts of menthol, 5-10 parts of borneol, 5-10 parts of camphor, 70-100 parts of natural rubber, 30-50 parts of rosin, 6-12 parts of vaseline, 1-5 parts of liquid paraffin, 5-10 parts of wool fat and 50-80 parts of far infrared ceramic powder.
4. An anti-inflammatory analgesic plaster composition as claimed in claim 1 or 2, characterized in that: the composite material comprises the following raw materials in parts by mass:
4 parts of star anise, 5 parts of rhizoma kaempferiae, 8 parts of angelica dahurica, 12 parts of rhizoma atractylodis, 12 parts of angelica, 17 parts of rhizoma zingiberis, 6 parts of radix aconiti agrestis, 6 parts of ligusticum wallichii, 9 parts of menthol, 7 parts of borneol, 7 parts of camphor, 95 parts of natural rubber, 40 parts of rosin, 9 parts of vaseline, 3.5 parts of liquid paraffin, 7.5 parts of lanolin and 65 parts of far infrared ceramic powder;
or,
2 parts of star anise, 10 parts of rhizoma kaempferiae, 5 parts of angelica dahurica, 15 parts of rhizoma atractylodis, 10 parts of angelica, 20 parts of rhizoma zingiberis, 5 parts of radix aconiti, 10 parts of radix aconiti agrestis, 5 parts of ligusticum wallichii, 12 parts of menthol, 5 parts of borneol, 10 parts of camphor, 70 parts of natural rubber, 50 parts of rosin, 6 parts of vaseline, 5 parts of liquid paraffin, 5 parts of lanolin and 80 parts of far infrared ceramic powder;
or,
6 parts of star anise, 3 parts of rhizoma kaempferiae, 10 parts of angelica dahurica, 10 parts of rhizoma atractylodis, 15 parts of angelica, 10 parts of rhizoma zingiberis, 10 parts of radix aconiti, 5 parts of radix aconiti agrestis, 10 parts of ligusticum wallichii, 6 parts of menthol, 10 parts of borneol, 5 parts of camphor, 100 parts of natural rubber, 30 parts of rosin, 12 parts of vaseline, 1 part of liquid paraffin, 10 parts of wool grease and 50 parts of far infrared ceramic powder.
5. A process for preparing an anti-inflammatory analgesic plaster composition as claimed in any one of claims 1 to 4, comprising the steps of:
(1) taking the aniseed, the rhizoma kaempferiae, the angelica dahurica, the rhizoma atractylodis, the angelica, the rhizoma zingiberis, the radix aconiti agrestis and the rhizoma ligustici wallichii with the formula amount, and processing the mixture into tablets or coarse powder;
(2) putting the raw material slices or coarse powder prepared in the step (1) into an extraction tank, and adding ethanol to soak for 10-16 hours;
(3) heating the soaked materials in an extraction tank to slightly boil for 1-3 hr, stopping heating, and recovering the extractive solution;
(4) adding ethanol into the raw materials extracted for the first time in the step (3), heating to slightly boil for 1-3 hours, stopping heating, and recovering the extracting solution;
(5) adding ethanol into the raw materials extracted for the second time in the step (4), heating to slightly boil for 1-3 hours, stopping heating, and recovering the extracting solution;
(6) mixing the extractive solutions obtained by the three-time heating extraction, heating and concentrating to obtain soft extract with relative density of 1.2-1.3 at 50 deg.C, cooling, filtering, and placing into a sealed container;
(7) adding the thick paste extracted in the step (6) into menthol, borneol, camphor, natural rubber, rosin, vaseline, liquid paraffin, lanolin and far infrared ceramic powder according to the formula amount, and stirring until the added materials are uniformly mixed to form the anti-inflammatory analgesic ointment composition.
6. The process for preparing an anti-inflammatory analgesic plaster composition according to claim 5, wherein: the soaking time in the step (2) is 12 hours; and (4) heating to slight boiling for 2 hours in the steps (3), (4) and (5), and stopping heating.
7. The process for preparing an anti-inflammatory analgesic plaster composition according to claim 5, wherein: and (6) heating and concentrating the mixed solution to obtain a thick paste with the relative density of 1.25 at 50 ℃.
8. The structure of the anti-inflammatory analgesic plaster consists of a backing material, a plaster layer and a plaster surface covering, and is characterized in that: the plaster layer is the anti-inflammatory analgesic plaster composition according to any one of claims 1 to 4.
9. The anti-inflammatory analgesic plaster of claim 8 wherein the backing material is a cloth or paper backing; the plaster surface covering is release paper or release film.
10. The process for preparing the anti-inflammatory analgesic plaster of claim 8, wherein the anti-inflammatory analgesic plaster composition of any one of claims 1 to 4 is uniformly spread on a backing material, covered with a release paper or film, cut, inspected, and packaged.
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| CN106491700A (en) * | 2016-12-29 | 2017-03-15 | 杨新 | A kind of channels and collaterals toxin expelling plaster |
| CN107970404A (en) * | 2017-11-02 | 2018-05-01 | 东莞市广易中医药发展有限公司 | A kind of nano antalgic patch and preparation method thereof |
| CN109908112A (en) * | 2019-04-19 | 2019-06-21 | 内蒙古科尔沁药业有限公司 | A kind of rubber paste emplastrum of not allergy and preparation method thereof |
| CN113813321A (en) * | 2021-09-30 | 2021-12-21 | 北京悬壶堂血栓中医学研究有限公司 | Cold plaster for treating carotid plaque and preparation method thereof |
| CN115364074A (en) * | 2022-08-24 | 2022-11-22 | 桂林清研皓隆新材料有限公司 | A kind of graphene far-infrared anti-inflammatory analgesic patch and preparation method thereof |
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| CN1334079A (en) * | 2000-07-17 | 2002-02-06 | 周松亮 | Far infrared rehabilitation medicine patch for dispelling wind-damp, promoting blood circulation, removing obstruction in channels, diminishing inflammation and easing pain and production method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106491700A (en) * | 2016-12-29 | 2017-03-15 | 杨新 | A kind of channels and collaterals toxin expelling plaster |
| CN107970404A (en) * | 2017-11-02 | 2018-05-01 | 东莞市广易中医药发展有限公司 | A kind of nano antalgic patch and preparation method thereof |
| CN109908112A (en) * | 2019-04-19 | 2019-06-21 | 内蒙古科尔沁药业有限公司 | A kind of rubber paste emplastrum of not allergy and preparation method thereof |
| CN113813321A (en) * | 2021-09-30 | 2021-12-21 | 北京悬壶堂血栓中医学研究有限公司 | Cold plaster for treating carotid plaque and preparation method thereof |
| CN115364074A (en) * | 2022-08-24 | 2022-11-22 | 桂林清研皓隆新材料有限公司 | A kind of graphene far-infrared anti-inflammatory analgesic patch and preparation method thereof |
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Application publication date: 20160928 |