CN113197844A - Scar-free tissue regeneration promoting paste - Google Patents
Scar-free tissue regeneration promoting paste Download PDFInfo
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- CN113197844A CN113197844A CN202110494397.4A CN202110494397A CN113197844A CN 113197844 A CN113197844 A CN 113197844A CN 202110494397 A CN202110494397 A CN 202110494397A CN 113197844 A CN113197844 A CN 113197844A
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Abstract
The invention discloses a scar-free granulation promoting ointment which comprises a main drug and an auxiliary drug, wherein the main drug comprises coptis chinensis, phellodendron, radix angelicae sinensis, lithospermum and radix rehmanniae; the adjuvant comprises radix astragali, fructus Gardeniae, radix Sophorae Flavescentis, and Saviae Miltiorrhizae radix; the main medicines have the effects of diminishing inflammation and sterilizing, promoting tissue regeneration and activating blood, and the auxiliary medicines have the effects of promoting qi circulation and relieving pain, and close pus can protect wounds. The invention has convenient use, short repair time, no relapse after repair, no scar, and effective scarless granulation promotion on various problems of wound, burn and scald, unhealed stubborn wound, bedsore, unhealed diabetic foot wound and the like.
Description
Technical Field
The invention relates to a tissue regeneration promoting paste, in particular to a scar-free tissue regeneration promoting paste, and belongs to the technical field of traditional Chinese medicines.
Background
In the prior art, patent CN 86108951 discloses a "low melting point ointment formulation and a process for preparing wet burn ointment", which mainly comprises the following components: the burn cream has the functions of clearing away heat and toxic materials, but has better functions of expelling pus, removing putrefaction and promoting granulation.
Patent CN95108098.9 discloses a burn and scald myogenic ointment with remarkable analgesic effect, blood circulation promoting and blood stasis removing, pus expelling, putrefaction removing, myogenic strength, quick wound repair, strong anti-infection ability, short treatment period, convenient use, no toxicity and no irritation. Comprises the following components: oil wax type matrix, at least one of coptis, scutellaria and phellodendron, frankincense and myrrh are added, and the components account for the total medicine amount (weight percent): coptis chinensis: 1 to 10 percent; scutellaria baicalensis: 1 to 10 percent; phellodendron bark: 1 to 10 percent; frankincense: 1 to 7 percent; myrrh: 1 to 7 percent. The burn and scald myogenic ointment selects myrrh with the functions of breaking blood and relieving pain, dissipating blood stasis and detumescence, relieving pain and promoting granulation and frankincense with the functions of relieving pain and growing flesh, promoting blood circulation and relieving pain and stretching muscle, and has the functions of promoting blood circulation and removing blood stasis, expelling pus and removing necrotic tissue and promoting granulation; the Chinese medicinal ointment resists the invasion of microorganisms to the wound surface by virtue of the heat-clearing and detoxifying functions of the coptis chinensis, the radix scutellariae and the golden cypress in the ointment, and has the function of resisting infection. The frankincense and the myrrh comprise the following components in percentage by weight: 1-7 percent of coptis root, 1-7 percent of radix scutellariae and phellodendron, which can be used singly or mixed together, and the weight ratio of the components is as follows: 1-10%, 1-10% and 1-10%. In order to facilitate use and create a good regeneration environment for the wound surface, the burn and scald myogenic ointment adopts an oil wax type matrix, is applied to the burn and scald wound surface, protects the wound surface, isolates air, prevents the excessive evaporation of the moisture of the wound surface, prevents the dehydration and drying of necrotic tissues, separates the necrotic tissues from the surface and the inside of the wound surface and living tissues and semi-dead and non-dead tissues without wound, stops the semi-dead and non-dead tissues from further necrosis, and simultaneously the wound surface grows under the moistening of ointment, so that the wound surface is not contractual and can heal in a small area by three degrees; the oil wax type matrix is formed by mixing sesame oil and beeswax, and aims to determine the thickness of a medicine coating layer according to the degree of wound so as to ensure that the ointment can be continuously warmed under the action of body temperature after being applied to the wound, so that the medicine application and drainage of the wound are convenient to maintain, dead tissues are discharged from the wound in advance, a relatively clean wound is generated, and the wound is convenient to repair.
For example, cn201510269268.x discloses a moist tissue regeneration promoting paste for treating bedsore, which comprises the following components in parts by weight: 2 parts of coptis chinensis, 1 part of astragalus, 1 part of phellodendron, 1 part of rhubarb, 2 parts of garden burnet, 2 parts of lithospermum, 2 parts of dried rehmannia root, 2 parts of angelica, 1 part of angelica dahurica, 1 part of bletilla striata, 1 part of cynanchum atratum, 2 parts of honeysuckle stem, 9 parts of beeswax, 20 parts of sesame oil and 0.3 part of borneol; the preparation process comprises the steps of putting all sesame oil into a pot, heating the oil with strong fire to 90 ℃, then adding the Chinese herbal medicine raw materials, decocting with strong fire for 30 minutes, and then decocting with slow fire for 60 minutes; secondly, decocting the mixture for 25 minutes by strong fire and 60 minutes by slow fire; thirdly, decocting for 15 minutes with strong fire for the third time and decocting for 60 minutes with slow fire; fourthly, deslagging and filtering are carried out when the liquid medicine is in a dripping bead shape; adding borneol and yellow wax into the filtered liquid medicine and stirring uniformly; sixthly, after the liquid medicine is naturally cooled, the liquid medicine is put into a container for standby. Has the advantages of good sterilization, anti-inflammation, promotion of local microcirculation, acceleration of wound healing and no side effect.
Related compositions are many, but no scars are left after the wound surface is healed, and the prior art has not reported.
Disclosure of Invention
The invention aims to solve the problems in the prior art and provides a scar-free tissue regeneration promoting paste.
In order to achieve the purpose, the technical means adopted by the invention is as follows: a granulation promoting paste without scar is prepared from main materials and adjuvant materials, wherein the main materials comprise Coptidis rhizoma, cortex Phellodendri, radix Angelicae sinensis, radix Arnebiae, and radix rehmanniae; the adjuvant comprises radix astragali, fructus Gardeniae, radix Sophorae Flavescentis, and Saviae Miltiorrhizae radix; the main medicines have the effects of diminishing inflammation and sterilizing, promoting tissue regeneration and activating blood, and the auxiliary medicines have the effects of promoting qi circulation and relieving pain, and close pus can protect wounds.
Further, the preparation method of the main drug and the adjuvant comprises the following steps: respectively taking sesame oil and a main drug, sesame oil and an auxiliary drug, respectively soaking the main drug and the auxiliary drug in the sesame oil for seven days, decocting with slow fire until the tablets become yellow and crisp, filtering with a superfine filter screen, and naturally cooling the decoction; when in use, the main drug and the adjuvant are combined into one; wherein, the volume-mass ratio of the sesame oil to the main drug and the auxiliary drug is 5: 0.8 to 1 ml/g.
Furthermore, the scar-free tissue regeneration promoting ointment is applied to scar-free tissue regeneration promoting of wounds, burns and scalds, unhealed wounds, bedsores and diabetic foot wounds.
Further, the main drug comprises 15-25% of coptis chinensis, 15-25% of phellodendron, 15-25% of angelica tail, 15-25% of lithospermum and 10-20% of radix rehmanniae.
Further, the adjuvant comprises 15-25% of astragalus membranaceus, 20-30% of gardenia, 15-25% of radix sophorae flavescentis and 25-30% of salvia miltiorrhiza.
The invention has the beneficial technical effects that: convenient use, short repair time, no recurrence after repair, no scar, and no scar generation, and is effective in promoting granulation without scar for wound, burn and scald, intractable wound disunion, decubital ulcer, diabetic foot wound disunion, etc.
Drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is a photograph showing a comparison between before and after repair in example 1 of the present invention;
FIG. 2 is a photograph comparing before and after repair in example 2 of the present invention;
FIG. 3 is a comparative photograph before and after repair of example 3 of the present invention;
FIG. 4 is a comparative photograph before and after repair of example 4 of the present invention;
FIG. 5 is a comparative photograph before and after repair of example 5 of the present invention;
FIG. 6 is a photograph showing a comparison between before and after repair in example 6 of the present invention.
Detailed Description
Example 1
Liao XX, male, age 63, Sichuan people, long-term settlement Kunming and unhealed wound caused by diabetic foot, the medicament of the invention is used for repairing rotten foot, the rotten foot is healed after continuous use for 90 days, and the rotten foot is not relapsed and has no scar, as shown in the comparison chart before and after repair shown in figure 1.
Example 2
Liu XX, male, 61 years old, Yiliang Luliangyang village people in the period of Yiliangyang society, severe burn and scald, and the patients are completely recovered by 11 times of repair by using the medicine of the invention, as shown in a comparison graph before and after repair shown in figure 2.
Example 3
Qin XX, female, 46 years old, Yiliang ancient town Anjiaqiaomiu people, feet are burned by hot pot soup, and other methods are adopted to treat the foot burn for ten days, and the muscle regeneration promoting ointment of the invention is used for treatment, and the rehabilitation lasts seven days, as shown in the comparison chart before and after repair shown in figure 3.
Example 4
Zhang X, female, 23 years old, Yiliang county, small street village, the incision of caesarean section is not healed, the hospital treatment is ineffective, the tissue regeneration promoting plaster is used for repairing for ten days and completely recovering, and a comparison chart before and after repairing is shown in figure 4.
Example 5
Shen X, male, 50 years old, Yiliang Zhushan village, severe scald of hand and arm, and scald repaired in time with ointment four hours, and the repair was completely recovered eleven times, as shown in the comparison chart before and after repair shown in FIG. 5.
Example 6
Lilanfen, female, 56 years old, Yiliang dog street town, six years bedridden, bedsore all ulcerated, use the ointment of the invention for 14 days, completely recovered, as shown in figure 6 before and after the comparison of the repair.
As can be seen from the above examples, the wound-healing and granulation-promoting ointment of the present invention has the following main functional indications: scald, burn, all wounds with broken skin, postoperative wound repair, chronic wound, foot and hand dehiscence, wound repair after cupping, diabetic foot and foot rot repair, wound infection, gynecological inflammation, hemorrhoid, pox repair, mouth and corner ulceration, and unhealed bedsore repair.
The main effects are as follows: the collagen-secreting fibroblast can effectively link wound infection, remove necrosis and promote tissue regeneration, quickly heal, and continuously ischemia and hypoxia-malnutrition of local tissues caused by pressure and the like to the skin with tissue ulceration and necrosis, so that the activity of cells is improved, the cell regeneration function is promoted, the collagen-secreting fibroblast is accelerated to grow, the damaged dermis is repaired, the collagen-secreting fibroblast can penetrate into skin epidermal cells to accelerate the metabolic capability, and the purpose of balancing the damaged skin is finally achieved.
The method is suitable for people: can be used for repairing wound surface of various wounds, postoperative wound, various skin-broken wounds, bedsore, ulcer, scald, burn, diabetic foot, and other unhealed wounds
The using method comprises the following steps: for external use, a proper amount of the product is taken and applied to the affected part once or twice a day, and the use frequency can be properly adjusted according to the condition.
Firstly, the affected part is cleaned by iodophor, then ointment is evenly smeared on a wound and covered by 6 layers of gauze, the dressing is fixed by adhesive plaster, dressing change is carried out once a day, the interval time is determined according to the wound size and the wound condition, the interval time is determined according to the amount of infected liquid, thick secretion is not afraid when dressing change is carried out, the necrotic tissue is liquefied and disintegrated, and the wound is normal as long as no red swelling exists around the wound, so that pus grows out.
The storage method comprises the following steps: the product should be stored in a non-corrosive gas, cool, dry, well ventilated and clean environment, and has an effective period: for 3 years.
Use contraindications: fish, shrimp, crab, seafood and seafood. Breeding allergic hair materials such as boars, sow meat, pig heads, pig feet, Chinese chives, caraway, wine, beef and mutton. People with antibiotic allergy or drug allergy of chronic diseases are used by doctors.
The following special indications are that: note that the distinction between adhesive plaster allergy and drug allergy is used.
The foregoing description of specific embodiments of the present invention has been presented. It is to be understood that the present invention is not limited to the specific embodiments described above, and various changes or modifications within the scope of the claims may be made by those skilled in the art without departing from the scope of the present invention.
Claims (5)
1. A scar-free tissue regeneration promoting paste is characterized in that: the traditional Chinese medicine composition is composed of a main medicine and an adjuvant medicine, wherein the main medicine is composed of coptis chinensis, phellodendron, radix angelicae sinensis, lithospermum and radix rehmanniae; the adjuvant comprises radix astragali, fructus Gardeniae, radix Sophorae Flavescentis, and Saviae Miltiorrhizae radix; the main medicines have the effects of diminishing inflammation and sterilizing, promoting tissue regeneration and activating blood, and the auxiliary medicines have the effects of promoting qi circulation and relieving pain, and close pus can protect wounds.
2. The scar-free muscle-regenerating ointment as claimed in claim 1, wherein: the preparation method of the main drug and the adjuvant comprises the following steps: respectively taking sesame oil and a main drug, sesame oil and an auxiliary drug, respectively soaking the main drug and the auxiliary drug in the sesame oil for seven days, decocting with slow fire until the tablets become yellow and crisp, filtering with a superfine filter screen, and naturally cooling the decoction; when in use, the main drug and the adjuvant are combined into one; wherein, the volume-mass ratio of the sesame oil to the main drug and the auxiliary drug is 5: 0.8 to 1 ml/g.
3. The scar-free tissue regeneration promoting ointment of claim 1 is applied to scar-free tissue regeneration of wounds, burns and scalds, unhealed wounds, bedsores and unhealed wounds of diabetic feet.
4. The scar-free muscle-regenerating ointment as claimed in claim 1, wherein: the main drug comprises 15-25% of coptis chinensis, 15-25% of phellodendron, 15-25% of angelica tail, 15-25% of lithospermum and 10-20% of radix rehmanniae.
5. The scar-free muscle-regenerating ointment as claimed in claim 1, wherein: the adjuvant comprises 15-25% of astragalus membranaceus, 20-30% of gardenia, 15-25% of radix sophorae flavescentis and 25-30% of salvia miltiorrhiza.
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| CN202110494397.4A CN113197844A (en) | 2021-05-07 | 2021-05-07 | Scar-free tissue regeneration promoting paste |
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| CN202110494397.4A CN113197844A (en) | 2021-05-07 | 2021-05-07 | Scar-free tissue regeneration promoting paste |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113855739A (en) * | 2021-11-25 | 2021-12-31 | 北京栋源堂科技有限公司 | Ointment patch for treating burns, scalds and non-healing wounds and preparation method and application |
| CN115969912A (en) * | 2022-12-12 | 2023-04-18 | 岳晖 | A topical Chinese medicinal composition for treating burn and scald, and its preparation method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113855739A (en) * | 2021-11-25 | 2021-12-31 | 北京栋源堂科技有限公司 | Ointment patch for treating burns, scalds and non-healing wounds and preparation method and application |
| CN115969912A (en) * | 2022-12-12 | 2023-04-18 | 岳晖 | A topical Chinese medicinal composition for treating burn and scald, and its preparation method |
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