CN103705817B - Traditional Chinese medicine for outer use for the treatment of tinea pedis and preparation method thereof - Google Patents
Traditional Chinese medicine for outer use for the treatment of tinea pedis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of traditional Chinese medicine for outer use for the treatment of tinea pedis and preparation method thereof, can effectively solve the topical therapeutic problem of tinea pedis. Medicine of the present invention is processed into by kuh-seng, the tuber of stemona, the root bark of shaggy-fruited dittany, corter pseudolaricis, sealwort, frutus cnidii, the fruit of summer cypress, dark plum, golden cypress, rheum officinale, cloves, pericarpium zanthoxyli, Radix Glycyrrhizae structure, make each efficacy of drugs produce synergy these drug regimens, thereby effectively play altogether heat-clearing and damp-drying drug, blood-nourishing skin-moisturizing, effect of killing parasites to relieve itshing. Use and there is good curative effect according to each component consumption. Wherein some drugs is pulverized to rear and another part drug extract mixing use, improve herbal medicine immersion drug effect, these drug regimens use simultaneously, because the present invention has taked technique scheme, compared with prior art, the present invention has abundant raw material, preparation technology is simple, easily produces, and cost is low, topical application is convenient, eutherapeutic advantage.
Description
Technical field
The present invention relates to traditional Chinese medicine, particularly a kind of traditional Chinese medicine for outer use for the treatment of tinea pedis and preparation method thereof.
Technical background
Tinea pedis is the superficial mycosis dermatoses that betides pedal skin, and the traditional Chinese medical science is called " tinea pedis ", is commonly called as " beriberi ". This disease is dermatology common disease, and frequently-occurring disease clinically occurs that taking toe seam, vola papule, blister, dipping erosion, dry furfur companion itch are as feature, and Xia Qiu is seriously ill, a lot of blisters, erosion, and Winter-Spring is sick light, and how dry breach, often involves adult. Be divided into three types according to its clinical manifestation, i.e. vesicle, erosive type and desquamative, can transform between three types mutually, but is main mainly with one or two types, often can cause onychomycosis, ringworm of the body, dermatophytids etc. In addition, the easy secondary bacterium of vesicle and erosive type infects, and causes erysipelas, lymphnoditis, angioleucitis, cellulitis etc. Tinea pedis is widely distributed, distributes higher, as the south China incidence of disease can reach 50%～60% with the torrid zone and subtropical zone, though this disease does not jeopardize patient's life, touching difficulty more, very easily recurs, and infectivity, the quality of life to patient and public health have brought many adverse effects.
Modern medicine thinks, the most common with Trichophyton rubrum in the common pathogen of tinea pedis, often causes desquamative infringement; Secondly be alpha fungus and acrothesium floccosum, often cause vesicle infringement. Dynamic epidemiological study to tinea pedis pathogenic fungus in recent years, statistics shows that infection by Candida albicans is in rising trend divided by outside encountered pathogenic bacteria, the tinea pedis due to it is the infringement of interphalangeal erosion type more. Mainly contain azole, polyenoid class etc. for the Western medicine preparation of nosomycosis treatment clinically at present, but various kinds of drug occurs the drug resistance problem of different strains to there is no the fine solution of method in the time of clinical application, as the continuous appearance of azole drug antibody-resistant bacterium and crossing drug resistant bacterial strain, original responsive drug susceptibility is reduced, and then make the kind that MIC value is higher infect more and more common. And patient is many owing to worrying the reasons such as Oral antifungal agents thing brings infringement to body and oral drugs are expensive, more options external application antifungal preparation treatment superficial mycoses clinically.
In recent years, many traditional Chinese medical science workers are in order to overcome drug resistance, side effect and the deficiency such as expensive of Western medicine antifungal preparation, in conjunction with modern means of science and technology, and further good, the has a broad antifungal spectrum of research safety, traditional Chinese anti-fungi medicines and compound thereof that curative effect is high. About Chinese medicine, the antibacterial action research of Common Pathogenic dermatophyte is mainly contained to single medicinal material and the antifungal activity in vitro of Chinese medicine compound prescription to dermatophyte and the research of mechanism thereof at present, comprise experimental study and clinical research two aspects. Researcher adopts semi-solid medicine base mixing method or micro-dilution method to come Study of Traditional Chinese Medicine water decoction, alcohol extract or wherein In Vitro Bacteriostasis or the bactericidal action of a or two kind of monomer component mostly. Wherein the laboratory research of Chinese herb compound and the experiment research of single medicinal material and means are basic identical, and the clinical research of Chinese herb compound is to study as many as the treatment of tinea of feet and hands, ringworm of the body common superficial mycoses.
In clinical practice uses, the local application for the treatment of tinea pedis selects upper Western medicine preparation more, next is the utilization of traditional Chinese medicine for external application associating Western medicine external preparation, therefore, how further effectively to screen and to extract the active component that has antifungic action in Chinese herbal medicine, find safe, effective, economic traditional Chinese anti-fungi medicines external preparation, should become an important research direction.
Summary of the invention
For above-mentioned situation, for overcoming the defect of prior art, the object of the invention is to provide a kind of traditional Chinese medicine for outer use for the treatment of tinea pedis and preparation method thereof, can effectively solve the topical therapeutic problem of tinea pedis.
For achieving the above object, the technical scheme that the present invention takes is that the traditional Chinese medicine for outer use of described treatment tinea pedis is to be made up of the medicine of following weight portion: 20～40 parts of kuh-sengs, 20～40 parts of the tubers of stemona, 20～40 parts of the root bark of shaggy-fruited dittanys, 20～40 parts of corter pseudolaricis, 20～40 parts of sealworts, 20～40 parts of frutus cnidiis, 20～40 parts of the fruit of summer cypress, 20～40 parts of dark plums, 10～20 parts of golden cypresses, 10～20 parts of rheum officinales, 5～15 parts of cloves, 5～15 parts of pericarpium zanthoxylis, 5～15 parts, Radix Glycyrrhizae.
For obtaining the traditional Chinese medicine for outer use of above-mentioned treatment tinea pedis, the preparation method that the present invention takes is: the kuh-seng of described weight portion, the tuber of stemona, the root bark of shaggy-fruited dittany, sealwort, dark plum, golden cypress, rheum officinale, cloves are pulverized respectively, cross 80 mesh sieves, be mixed into fine powder; The decocting that the corter pseudolaricis of described weight portion, frutus cnidii, the fruit of summer cypress, pericarpium zanthoxyli, Radix Glycyrrhizae five kinds of Chinese medicine are doubled to add after consumption 8 times boils 1.5h, filter to obtain decocting liquid, then in the dregs of a decoction, add the decocting of 6 times to boil 1.5h, filter to obtain decocting liquid, merge decocting liquid twice, be condensed into the medicinal extract that relative density is 1.25 left and right; Above-mentioned fine powder and medicinal extract are mixed and are placed in baking oven, 80 DEG C be dried to moisture and be less than 5% after, take out, then row pulverizes, become the fine powder of granularity approximately 180 μ m, place in clean container, under room temperature, press the packing of 25g/ bag specification.
Medicament selection kuh-seng of the present invention, the tuber of stemona, the root bark of shaggy-fruited dittany, corter pseudolaricis, sealwort, frutus cnidii, the fruit of summer cypress, dark plum, golden cypress, rheum officinale, cloves, pericarpium zanthoxyli, Radix Glycyrrhizae combine, make each efficacy of drugs produce synergy these drug regimens, thereby effectively play altogether heat-clearing and damp-drying drug, blood-nourishing skin-moisturizing, effect of killing parasites to relieve itshing.
Said medicine, wherein: kuh-seng: remove root head and little fibrous root, after cleaning, take advantage of fresh slices dry, raw using; There is heat-clearing and damp-drying drug, desinsection, effect of diuresis. The tuber of stemona: remove fibrous root, clean, dry, cut the raw use of sheet; Have and moisten the lung and relieve the cough, effect of desinsection delousing. The root bark of shaggy-fruited dittany: remove impurity, chip drying, raw using; There is heat-clearing and damp-drying drug, effect of the removing toxic substances of dispeling the wind. Corter pseudolaricis: remove impurity, dry, raw using; There is desinsection, antipruritic effect. Sealwort: cleaning, drying, cut sheet and use; There is boosting qi and nourishing yin, invigorating the spleen, moistening lung, effect of kidney-nourishing. Frutus cnidii: remove impurity, dry, raw using; There is killing parasites to relieve itshing, eliminating dampness, effect of warming kidney to invigorate yang. The fruit of summer cypress: remove impurity, dry, raw using; There is promoting diuresis for stranguria, clearing heat and promoting diuresis, antipruritic effect. Dark plum: after low temperature drying, stoning is raw to be used; Have and astringe the lung to stop cough, relieving diarrhea with astringents, relieving pain by calming ascaris, the effect promoting the production of body fluid to quench thirst. Golden cypress: dry, section or chopping are raw to be used; Have heat-clearing and damp-drying drug, purging intense heat is except steaming, effect of detoxification sore treatment. Rheum officinale: except removing root, scrape off crust stripping and slicing dry, raw using; There is heat and toxic materials clearing away, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, the effect of stimulating the menstrual flow by the stasis of blood. Cloves: remove impurity, dry, raw using; There is warming middle energizer to descend adverse-rising qi, eliminating cold to stop pain, effect of warming kidney and enhancing yang. Pericarpium zanthoxyli: remove seed and impurity, dry, raw using; There is warming middle energizer to relieve pain, effect of killing parasites to relieve itshing. Radix Glycyrrhizae: remove fibrous root, dry, cut the raw use of sheet; Have and invigorate the spleen and benefit qi, expelling phlegm and arresting coughing, relieving spasm to stop pain, clearing heat and detoxicating, effect of coordinating the drug actions of a prescription.
Tinea pedis is mainly due to wind, wet, heat, the excessive invasion and attack of worm from the mechanism of its morbidity of tcm theory, strongly fragrant in space between skin and muscles, excessive due to the skin. If see bleb, erosion, seepage flow taste water, itch incrustation person, mostly be damp and hot Sheng and cause; If see pachyderma, crack from dryness, itch person has hot and suffocating dryness-transformation more, qi and blood discord, due to failure of skin and muscle to be nourished. Work as heat-clearing and damp-drying drug therefore control, blood-nourishing skin-moisturizing, killing parasites to relieve itshing. The kind heat-clearing and damp-drying drug of kuh-seng merit, desinsection diuresis in side, the tuber of stemona has the use of desinsection delousing, and the two is combined into monarch drug in a prescription, plays altogether the antipruritic effect of removing dampness and destroying parasites; The root bark of shaggy-fruited dittany, corter pseudolaricis, frutus cnidii, the fruit of summer cypress, dark plum are ministerial drug altogether, with the efficacy of a drug of principal drug assistance killing parasites to relieve itshing; Golden cypress, rheum officinale heat-clearing and damp-drying drug share and control tinea, are aided with sealwort nature and flavor sweet flat, and blood-nourishing skin-moisturizing is antipruritic, and cloves, pericarpium zanthoxyli are pungent, temperature, and killing parasites to relieve itshing, is adjutant altogether, to help the antipruritic power of full side removing dampness and destroying parasites; Radix Glycyrrhizae coordinating the drug actions of a prescription is for making medicine. Full side integrate bitter cold, Xin Wen, Gan Pingzhu medicine, and the special killing parasites to relieve itshing of power makes eliminating dampness and not too simultaneously, and temperature is supported moisturizing and not stagnant wet, entirely just plays altogether heat-clearing and damp-drying drug, blood-nourishing skin-moisturizing, the merit of killing parasites to relieve itshing. Confirm according to modern pharmacological research: multiple Chinese herbal medicine has antifungic action, according to incomplete statistics, reported that more than 300 kind of Chinese herbal medicine has antifungic action in various degree, as matrine has stronger bacteriostasis to Trichophyton rubrum; The monomer composition Chrysophanol of rheum officinale has stronger bacteriostasis to Trichophyton rubrum; Pericarpium zanthoxyli volatile oil has and suppresses and killing effect Trichophyton rubrum, microsporum lanosum etc.; Dark plum mainly contains citric acid, malic acid, and the materials such as butanedioic acid, water decoction has inhibitory action to multiple pathogenic bacteria and dermatophyte in vitro; Volatile clove oil has the effect of stronger anti-deep fungal; Frutus cnidii is very strong to the inhibitory action of Candida albicans; Fruit of summer cypress water logging agent all has inhibitory action in various degree etc. to dermatophytes such as rust budlet spore tinea bacterium, ulotrichy budlet spore tinea bacterium.
Because the present invention has taked technique scheme, compared with prior art, the present invention has abundant raw material, and preparation technology is simple, easily produces, and cost is low, and topical application is convenient, eutherapeutic advantage.
Detailed description of the invention
The traditional Chinese medicine for outer use for the treatment of tinea pedis of the present invention is to be made up of the medicine of following weight portion: 20～40 parts of kuh-sengs, 20～40 parts of the tubers of stemona, 20～40 parts of the root bark of shaggy-fruited dittanys, 20～40 parts of corter pseudolaricis, 20～40 parts of sealworts, 20～40 parts of frutus cnidiis, 20～40 parts of the fruit of summer cypress, 20～40 parts of dark plums, 10～20 parts of golden cypresses, 10～20 parts of rheum officinales, 5～15 parts of cloves, 5～15 parts of pericarpium zanthoxylis, 5～15 parts, Radix Glycyrrhizae.
For obtaining the traditional Chinese medicine for outer use of above-mentioned treatment tinea pedis, the preparation method that the present invention takes is: the kuh-seng of described weight portion, the tuber of stemona, the root bark of shaggy-fruited dittany, sealwort, dark plum, golden cypress, rheum officinale, cloves are pulverized respectively, cross 80 mesh sieves, be mixed into fine powder; The decocting that the corter pseudolaricis of described weight portion, frutus cnidii, the fruit of summer cypress, pericarpium zanthoxyli, Radix Glycyrrhizae five kinds of Chinese medicine are doubled to add after consumption 8 times boils 1.5h, filter to obtain decocting liquid, then in the dregs of a decoction, add the decocting of 6 times to boil 1.5h, filter to obtain decocting liquid, merge decocting liquid twice, be condensed into the medicinal extract that relative density is 1.25 left and right; Above-mentioned fine powder and medicinal extract are mixed and are placed in baking oven, 80 DEG C be dried to moisture and be less than 5% after, take out, then row pulverizes, become the fine powder of granularity approximately 180 μ m, place in clean container, under room temperature, press the packing of 25g/ bag specification.
Below in conjunction with embodiment, the specific embodiment of the present invention is elaborated
Embodiment mono-:
The traditional Chinese medicine for outer use for the treatment of tinea pedis of the present invention is to be made up of the medicine of following weight portion: 20 parts of kuh-sengs, 20 parts of the tubers of stemona, 20 parts of the root bark of shaggy-fruited dittanys, 20 parts of corter pseudolaricis, 20 parts of sealworts, 20 parts of frutus cnidiis, 20 parts of the fruit of summer cypress, 20 parts of dark plums, 10 parts of golden cypresses, 10 parts of rheum officinales, 5 parts of cloves, 5 parts of pericarpium zanthoxylis, 5 parts, Radix Glycyrrhizae.
For obtaining the traditional Chinese medicine for outer use of above-mentioned treatment tinea pedis, the preparation method that the present invention takes is: the kuh-seng of described weight portion, the tuber of stemona, the root bark of shaggy-fruited dittany, sealwort, dark plum, golden cypress, rheum officinale, cloves are pulverized respectively, cross 80 mesh sieves, be mixed into fine powder; The decocting that the corter pseudolaricis of described weight portion, frutus cnidii, the fruit of summer cypress, pericarpium zanthoxyli, Radix Glycyrrhizae five kinds of Chinese medicine are doubled to add after consumption 8 times boils 1.5h, filter to obtain decocting liquid, then in the dregs of a decoction, add the decocting of 6 times to boil 1.5h, filter to obtain decocting liquid, merge decocting liquid twice, be condensed into the medicinal extract that relative density is 1.25 left and right; Above-mentioned fine powder and medicinal extract are mixed and are placed in baking oven, 80 DEG C be dried to moisture and be less than 5% after, take out, then row pulverizes, become the fine powder of granularity approximately 180 μ m, place in clean container, under room temperature, press the packing of 25g/ bag specification.
Embodiment bis-:
The traditional Chinese medicine for outer use for the treatment of tinea pedis of the present invention is to be made up of the medicine of following weight portion: 30 parts of kuh-sengs, 30 parts of the tubers of stemona, 30 parts of the root bark of shaggy-fruited dittanys, 30 parts of corter pseudolaricis, 30 parts of sealworts, 30 parts of frutus cnidiis, 30 parts of the fruit of summer cypress, 30 parts of dark plums, 15 parts of golden cypresses, 15 parts of rheum officinales, 10 parts of cloves, 10 parts of pericarpium zanthoxylis, 10 parts, Radix Glycyrrhizae.
Its preparation method is with embodiment mono-.
Embodiment tri-:
The technical scheme that the present invention takes is that the traditional Chinese medicine for outer use of described treatment tinea pedis is to be made up of the medicine of following weight portion: 40 parts of kuh-sengs, 40 parts of the tubers of stemona, 40 parts of the root bark of shaggy-fruited dittanys, 40 parts of corter pseudolaricis, 40 parts of sealworts, 40 parts of frutus cnidiis, 40 parts of the fruit of summer cypress, 40 parts of dark plums, 20 parts of golden cypresses, 20 parts of rheum officinales, 15 parts of cloves, 15 parts of pericarpium zanthoxylis, 15 parts, Radix Glycyrrhizae.
Its preparation method is with embodiment mono-.
(1) major function of medicine of the present invention and therapeutic domain
1. major function:
Heat-clearing and damp-drying drug, blood-nourishing skin-moisturizing, killing parasites to relieve itshing.
2. therapeutic domain:
Be applicable to the treatment of clinical common vesicle, erosive type and desquamative three types tinea pedis.
3. usage and consumption
(1) clean foot: clean pedal skin by warm water. (2) configuration tinea pedis soak: get one bag of medicinal powder (25g/ bag), put into clean basin, add the about 1500ml of warm water of 35～40 DEG C to stir. (3) soak: trouble foot is put into soak and soak after 30～40 minutes, wipe dry with sterile gauze. Every day 1 time, being used in conjunction 2 weeks is 1 course for the treatment of. (4) during medication, enjoin patient should change clean footgear every day, stop using other are put preparation on the skin and avoid contacting the alkaline matter such as soap, hand cleanser outward simultaneously.
(2) clinical observation of medicine of the present invention
1. case selection standard:
(1) diagnostic criteria: formulate with reference to national state-compiled textbook " skin cypridology " the 7th edition and " Surgery of Chinese Medicine " the 7th edition diagnostic criteria about tinea pedis.
Bubble type: the both sides that are 1. apt to occur in arch of foot and toe; 2. local mostly be in groups or disperses deeply in the subcutaneous blister of property, blister wall thickness, content is limpid, is difficult for breaking, dry furfur or be fused into kerionic vesicle after a couple of days, tears blister wall off and can show honeycomb substrate and cerise erosion face; 3. itch.
Erosive type: 1. betide between toe seam, especially with common between 3,4 toes; 2. part shows as humidity between toe more, and skin dipping turns white; 3. violent itch, often scratches to the rotten pain of skin, seepage flow watery blood, easily accompanying infection.
Desquamative: be 1. apt to occur in heel and sufficient sole of the foot portion; 2. locally show as cutin more and thicken, dry, coarse, furfur, texture is deepened, and easily chaps, hemorrhage, and skin damage also can spread to instep; 3. generally without itch, pain while chapping.
(2) inclusive criteria:
1. meet three types tinea pedis diagnostic criteria person;
2. the range of age is 16-68 year person;
3. directly microscopy is found pathomycete person;
4. in two weeks, do not accept other drug to tinea pedis treating person;
5. the person that signs Informed Consent Form.
(3) exclusion standard:
1. be not inconsistent diagnostic criteria person;
2. age below 16 years old or more than 68 years old, lactation and gravidic women;
3. there is miconazole nitrate allergies person;
4. other antifungal drugs history person is crossed in oral in 2 weeks or external application;
5. merge the primary disease persons such as serious cardiovascular, the cerebrovascular, liver, kidney, hemopoietic system, diabetes, malignant tumour, mental patient.
(4) rejecting and abort criterion:
1. not by scheme medication, affect validity and security judgement person;
2. bolter voluntarily in research process;
3. data is incomplete, affects validity and security judgement person.
4. in therapeutic process, the person that occurs serious adverse reaction.
2. observational technique:
(1) case grouping:
Adopt method random, contrast, MethodsThe cases enrolled is divided into 2 groups for the treatment of group and control groups at random.
(2) methods for the treatment of:
Treatment group: external application Chinese medicine preparation of the present invention soaks, and every day 1 time, gets one bag of medicinal powder (25g/ bag), puts into clean basin, foams foot 30～40 minutes after adding the about 1500ml of warm water of 35～40 DEG C to stir, and being used in conjunction 2 weeks is 1 course for the treatment of.
Control group: external application has the miconazole nitrate cream (trade name: Da Kening of definite good therapeutic effect; Manufacturer: Xian-Janssen Pharmaceutical Ltd.; Authentication code: the accurate word H61020001 of traditional Chinese medicines), outer wiping affected part, every day 2 times, being used in conjunction 2 weeks is 1 course for the treatment of.
(3) observation index: damage size and itch light and heavy degree formulation observation index, point level Four scoring according to skin.
Skin damages area: 0 point, do not have skin to damage; 2 points, skin damages area and accounts for below 1/3 of foot area; 4 points, skin damages area and accounts for the more than 1/3 of foot area, below 2/3; 6 points, skin damages area and accounts for the more than 2/3 of foot area.
Itch degree: 0 point, without itch; 2 points, accidental micro-itching; 4 points, paroxysmal itch; 6 points, continuation itch, and impact study, work and life.
(4) record case: observe once weekly, in time record patient change of illness state situation.
3. therapeutic evaluation:
Draft curative effect determinate standard with reference to " clinical disease diagnosis is according to curing improvement standard " and " disease of tcm Standardization of diagnosis and curative effect ", according to therapeutic index, binding to fungal microscopy result is carried out efficacy determination.
(1) therapeutic index: symptom total mark × 100% before therapeutic index=(the rear symptom total mark of symptom total mark-treatment before treatment)/treatment.
(2) efficacy determination:
1. recovery from illness, therapeutic index >=90%, continuous 4 equal negative patients of the direct microscopy of fungi;
2. effective: 70%≤therapeutic index < 90%, continuous 4 direct microscopies of fungi, wherein 2 persons that are not negative above;
3. effective: 30%≤therapeutic index < 70%, continuous 4 direct microscopies of fungi, wherein 1 negative patient;
4. invalid: therapeutic index < 30%, continuous 4 direct microscopies of fungi person that is not all positive.
(3) statistical method: all data acquisitions are undertaken by SPSS12.0 statistical analysis system.
4. result: treatment group 70 examples, recovery from illness 44 examples, effective 14 examples, effective 4 examples, invalid 8 examples, total effective rate 88.57%; Control group 72 examples, recovery from illness 44 examples, effective 10 examples, effective 6 examples, invalid 12 examples, total effective rate 83.33%. Learn and process by statistics, relatively there was no significant difference (P > 0.05) of two groups of general curative effects.
From treatment results, can find out, the Chinese medicine preparation clinical application that treatment group is used is effective.
In above-mentioned therapeutic process, the appearance that has no adverse reaction, drug safety, and recurrence rate is low.
5. conclusion: by clinical observation, prove that the present invention has good therapeutic effect to tinea pedis topical therapeutic. Traditional Chinese medicine foot bath, medicine absorbs by foot, has not only played the effect of killing fungus treatment tinea pedis, simultaneously by medicine and warmth sensation to foot the spread effect through cave, the inclined to one side Sheng of adjusting energy and blood of human body, negative and positive declines partially, improves the externally resistance of heresy of human body, thereby has reduced the recurrence rate of tinea pedis. In addition, topical transdermal absorbs the drug and can also avoid stimulation and the bad reaction of medicine to stomach and intestine. This external medicine preparation, easy to use, safety, effectively, has no adverse reaction, and cost is low, easily produces, and has more outstanding clinical meaning, is the innovation on topical therapeutic tinea pedis medicine, and economic and social benefit is huge.
Claims (2)
1. treat a traditional Chinese medicine for outer use for tinea pedis, the traditional Chinese medicine for outer use that it is characterized in that described treatment tinea pedis is to be made up of the medicine of following weight portion: 20～40 parts of kuh-sengs, 20～40 parts of the tubers of stemona, 20～40 parts of the root bark of shaggy-fruited dittanys, 20～40 parts of corter pseudolaricis, 20～40 parts of sealworts, 20～40 parts of frutus cnidiis, 20～40 parts of the fruit of summer cypress, 20～40 parts of dark plums, 10～20 parts of golden cypresses, 10～20 parts of rheum officinales, 5～15 parts of cloves, 5～15 parts of pericarpium zanthoxylis, 5～15 parts, Radix Glycyrrhizae.
2. treat as claimed in claim 1 the preparation method of tinea pedis traditional Chinese medicine for outer use for one kind, it is characterized in that this preparation method is: the kuh-seng of described weight portion, the tuber of stemona, the root bark of shaggy-fruited dittany, sealwort, dark plum, golden cypress, rheum officinale, cloves are pulverized respectively, cross 80 mesh sieves, be mixed into fine powder; The decocting that the corter pseudolaricis of described weight portion, frutus cnidii, the fruit of summer cypress, pericarpium zanthoxyli, Radix Glycyrrhizae five kinds of Chinese medicine are doubled to add after consumption 8 times boils 1.5h, filter to obtain decocting liquid, then in the dregs of a decoction, add the decocting of 6 times to boil 1.5h, filter to obtain decocting liquid, merge decocting liquid twice, be condensed into relative density and be 1.25 medicinal extract; Above-mentioned fine powder and medicinal extract are mixed and are placed in baking oven, 80 DEG C be dried to moisture and be less than 5% after, take out, then row pulverizes, become the fine powder of granularity 180 μ m, place in clean container, under room temperature, press the packing of 25g/ bag specification.
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| CN104043005A (en) * | 2014-07-09 | 2014-09-17 | 华菊 | Medicine for treating tinea manus and tinea pedis |
| CN105125987A (en) * | 2015-09-09 | 2015-12-09 | 桂林盛兴电子科技有限公司 | External ointment for treating onychomycosis and preparation method thereof |
| CN105213913A (en) * | 2015-11-13 | 2016-01-06 | 青岛市市立医院 | A kind of foam washing liquid for the treatment of tinea pedis |
| CN105943665A (en) * | 2016-03-07 | 2016-09-21 | 合肥工业大学 | External-use powder for treating tinea pedis |
| CN106039167A (en) * | 2016-08-16 | 2016-10-26 | 成都中医药大学附属医院 | Medicine composition for treating tinea manuum and tinea pedis, preparation method and application thereof |
| CN114788854B (en) * | 2022-04-24 | 2023-09-12 | 杨治 | Traditional Chinese medicine composition and preparation method and application thereof |
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| CN1292268A (en) * | 2000-04-24 | 2001-04-25 | 缪振兴 | Medicine for curing tinea unguium |
| CN101664526A (en) * | 2008-09-02 | 2010-03-10 | 陈瑞华 | External Chinese medicinal lotion |
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| CN1292268A (en) * | 2000-04-24 | 2001-04-25 | 缪振兴 | Medicine for curing tinea unguium |
| CN101664526A (en) * | 2008-09-02 | 2010-03-10 | 陈瑞华 | External Chinese medicinal lotion |
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| CN103705817A (en) | 2014-04-09 |
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