CN108310255A - A kind of Chinese herb bath stain preparation and preparation method thereof for treating eczema - Google Patents

A kind of Chinese herb bath stain preparation and preparation method thereof for treating eczema Download PDF

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CN108310255A
CN108310255A CN201810421029.5A CN201810421029A CN108310255A CN 108310255 A CN108310255 A CN 108310255A CN 201810421029 A CN201810421029 A CN 201810421029A CN 108310255 A CN108310255 A CN 108310255A
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parts
preparation
chinese herb
eczema
decoction
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张安林
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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Abstract

The present invention provides a kind of Chinese herb bath stain preparations and preparation method thereof for treating eczema;Belong to technical field of traditional Chinese medicines;The Chinese herb bath stain preparation includes following raw material:Cassia twig, elscholtiza, Radix Paeoniae Alba, dark plum, cicada slough, paniculate swallowwort, the fruit of summer cypress, dittany bark, raw radix scutellariae, bamboo juice or raw caulis bambusae in taenian, Fructus Forsythiae, oldenlandia diffusa, nine inner bright, purslane, kiss-me, centella, Ramulus euonymi, frutus cnidii, licorice, radix rehmanniae recen, Radix Astragali.The preparation method of the Chinese herb bath stain preparation includes the following steps:1) 20~80min of Chinese medicine material is impregnated with normal-temperature water;2) intense fire is fried boiling, and changes after being cooked by slow fire 30min, detaches decoction liquor;By the dregs of a decoction, intense fire is fried boiling into the water, is cooked by slow fire 20min, detaches decoction liquor again, and head, which is decocted, mixes i.e. acquisition Chinese herb bath stain preparation with secondary decoction liquor.The Chinese herb bath stain formulation application produces effects very prompt in anxious, sub-, chronic partially wet and heat type atopic eczema.

Description

A kind of Chinese herb bath stain preparation and preparation method thereof for treating eczema
Technical field
The invention belongs to technical field of traditional Chinese medicines more particularly to a kind of Chinese herb bath stain preparation for treating eczema and its preparation sides Method.
Background technology
Eczema is clinical most common multiple allergic disease.Its clinical manifestation is red pimple, erythema, itch play Strong, water sore, sepage, yellow water be dripping, rotten to the corn, incrustation, infiltration and chap etc..
The cause of disease of eczema, the interpretation of the cause, onset and process of an illness, clinical manifestation are extremely complex, are a kind of common tables caused by a variety of inside and outside factors The specific abnormalism inflammatory dermatoses of skin and its skin shallow-layer.The pathogenic factor of eczema is extremely complex, related with allergy, by day Often in life caused by the stimulants such as contact detergent, soap, dyestuff, paint and daylight, pollen.In lysis, spirit wound The factors such as wound, endocrine disorder can aggravate the state of an illness.It is broadly divided into two kinds inside and outside.Internal cause and chronic digestive system disease, stomach Intestinal dysfunction, intemperance of taking food, the dysfunction of the spleen in transport, retention of damp-heat in the interior, stress, insomnia, mood change, or suffer from his disease, such as kidney, liver The factors such as disease, habitual constipation and heredity are related;External cause and daylight, cold, sweltering heat, humidity, chemicals (detergent, makeup Product, hair dye, preservative etc.), metal product (jewellery, watch chain, mirror holder), fish, shrimp, capsicum, tomato, pineapple, milk and animal The factors such as fur, feather are related.Region following the line of the sea in south China, subtropical zone, as Hong Kong, Macao, Taiwan, Guangdong and Guangxi Provinces, Shenzhen, Hainan, One band such as Fujian, Jiangsu and Zhejiang Provinces and periphery neighbouring country are new, horse, Thailand, get over, is remote, printing, old, Fei Deng states, since hot climate is moist, eczema Incidence is very high, some special work posts, and such as a long time in underground, underwater work, environmental sanitation cleaner, group of army etc. are because of humid environment It is sultry, often in contact with poisonous and harmful substance, or wear air-locked rubber overshoes, bucket shoes, using plastic glove etc., cause it is damp and hot accumulate steam it is wet Rash incidence is very high.Obtaining eczema makes one itch unbearably, and no matter allergic eczema has been suffered from which position of body, all can be because of play Strong itch brings larger pain to patient, or even influences its normal work, life, and treatment for a long time is not thorough and can lead Cause apathetic, irritated and mental element obstacle.Eczema in addition to can other than concurrent common staphylococcus aureus skin infection, than More rare seems herpes simplex infections, wart or infectiousness patch.
The characteristics of incidence of eczema is:1, any age can fall ill, and be more with child and juvenile onset.2, can occur In any position of body surface, with after head, ear, vulva, crissum, brothers are common or whole skin is distributed, and more symmetry point Cloth.3, fash is polymorphism, divides acute stage (papule, erythema, blister, erosion, exudation), subacute stage (incrustation, the scales of skin that peel off, infiltration) With chronic phase (plumpness, mossization, pigmentation).4, easy recurrent exerbation, the course of disease is irregular, and conversion alternating can be taken into account between three phases Morbidity.
Often there are many forms for eczema, are easy mitigation, exacerbation or recurrence, boundary is generally not clear.Fash be easy to happen in Both sides are simultaneously more or less symmetrical, had erythema, papule, blister, erosion, the scales of skin that peel off, scab, pigment to increase according to acute or chronic degree It adds deduct less, chap or the different performances such as moss sample, wherein several performances are often mixed in together, successively occur sometimes. If any secondary infection, can also there are the skin lesions such as warts.
In eczema early stage or acute phase, affected part has sheet of erythema, intensive or evacuation small papule or naked eyes difficulty to see Blister, have large stretch of sepage and erosion when serious;In subacute state, sepage reduces and incrustation, and affected part becomes dark red by scarlet, does not have There is large stretch of erosion;In chronic states, sepage is less or is completely dried and forms a scab, and scales of skin that peel off scab is often mixed with the scales of skin that peel off, suffers from Place's color is darker or pigmentation occurs, and pigment is reduced sometimes, is easy to happen at the larger position of dermatoglyph especially movement degree Breach, long-term friction scratching can cause significant moss sample and neurodermatitis lichen simplex chronicus, be not easy to distinguish.
Eczema includes mainly following several specific types:
1) exudative type eczema
It is common in endomorphy type baby, just arises from two cheeks, erythema, papule, papulo-vesicle occurs, often appears and has because itching is scratched The scarlet rotten to the corn face of volume sepage.Severe patient can involve entire face even whole body.If any the visible warts of secondary infection and part Enlargement of lymph nodes, fever;
2) drying type eczema
It is more common in thin and weak baby.The positions such as scalp, glabella are apt to occur in, show as flush, furfur, papule, but without apparent Exudation.In it is chronic when also can mild infiltration it is plump, have chap, scratch or knot scab.Often cause baby because of the violent itch of paroxysmal Vagitus makes a noise and sleep disorder;
3) childhood eczema
It is a kind of children's anaphylaxis dermatosis.Child skin development is still unsound, and the cuticula of outermost layer epidermis is very thin, hair Thin rete vasculosum is abundant, and endothelium is aqueous and chloride is relatively abundanter, therefore is easy to happen the reaction of allergy eczema;
4) eczema mammae
It is more common in nursing women, mammary areola moistening, rotten to the corn, incrustation, the time can slightly thicken, chap long, pain when breast-feeding. It is not cured for a long time.Subcutaneously there is scleroma person, is considered as the possibility of concurrent eczematoid carcinoma.So should enhance your vigilance to eczema mammae, in time It checks;
5) eczema of scrotum
Acute person has swelling, flowing water, incrustation.Chronic person then thickens, lichenification, very itches and easily recurs.Often and ephidrosis, Vulva stimulation, neuroendocrine disorders, chronic prostatitis etc. are related;
6) pudendum eczema
Common big nymphae and neighbouring red swelling of the skin, erosion and it is chronic thicken, very itch.Often with colpomycosis, leukorrhea Increase and endocrine disturbance is related;
7) eczema of anus
Perianal eczema acute stage, is red and swollen, rotten to the corn, and chronic phase is in infiltration, plumpness, or even chaps.It is strange to itch and pain, It is especially more obvious after relieved.Due to often scratching, skin can thicken or thinning, and atrophy is shinny.Children's eczema of anus mostly with Pinworm is related, and adult is mostly related with hemorrhoid, hidrosis;
8) hand eczema
It betides palmar hand easily infiltration to thicken, hyperkeratosis forms chap.Finger end eczema often repeated blister, knot Scab thickens, furfur, and nail development can be influenced by involving nail matrix portion, cause deck coarse, recess is uneven.Contact water, soap, laundry Powder etc. often makes eczema aggravate;
9) leg foot eczema
Well send out shin before and ankle, often since varix of lower limb or wound cause.Knot is crazy about, thickens, mossization, also can be in gruel Rotten, flowing water, easy secondary infection or formation ulcer, it is obstinate refractory;
10) eczema fissum
It is related with allergy, caused by contacting the stimulants such as detergent, soap, dyestuff, paint and daylight in daily life. In lysis, the factors such as mental wound, endocrine disorder can aggravate the state of an illness.
Atopic eczema treatment not in time or therapy association of section does not cause chromogenesis calm or scar.Traditional doctor trained in Western medicine Eczema is treated, regardless of patient, regardless of sick type, illness all to eliminate based on surface inflammation, is mostly used greatly a kind for the treatment of, only pure Ground carries out external medicine-feeding treatment, can not solve the morbidity root and sensibiligen of eczema, it is easy to recur;And it is palliative, It is not from internal therapentics, drug is combined with instrument, and based on antiallergic Western medicine for oral administration and external application hormone therapy, prolonged application can produce Raw toxic side effect damages human body larger, be discontinued easy knock-on and recurrence.
Invention content
In view of this, the purpose of the present invention is to provide the Chinese herb baths of a kind of efficient, safety, treatment eczema easy to use Stain preparation and preparation method thereof.
In order to achieve the above-mentioned object of the invention, the present invention provides following technical scheme:A kind of Chinese herb bath stain system for treating eczema Agent includes the raw material of following parts by weight:10~20 parts of cassia twig, 10~16 parts of elscholtiza, 25~35 parts of Radix Paeoniae Alba, 35~45 parts of dark plum, 10~20 parts of cicada slough, 15~25 parts of paniculate swallowwort, 15~25 parts of the fruit of summer cypress, 20~30 parts of dittany bark, raw 25~35 parts of radix scutellariae, bamboo juice 10~20 parts, 15~25 parts of Fructus Forsythiae, 20~30 parts of oldenlandia diffusa, 20~30 parts of nine inner bright, 25~35 parts of purslane, kiss-me 20~30 parts, 20~30 parts of centella, 15~25 parts of Ramulus euonymi, 15~25 parts of frutus cnidii, 25~35 parts of licorice, radix rehmanniae recen 20 ~30 parts, 25~35 parts of Radix Astragali.
Preferably, include the raw material of following parts by weight:15 parts of cassia twig, 13 parts of elscholtiza, 20 parts of Radix Paeoniae Alba, 40 parts of dark plum, cicada slough 15 parts, 20 parts of paniculate swallowwort, 20 parts of the fruit of summer cypress, 25 parts of dittany bark, raw 30 parts of radix scutellariae, 15 parts of bamboo juice, 20 parts of Fructus Forsythiae, oldenlandia diffusa 25 parts, 25 parts of nine inner bright, 30 parts of purslane, 25 parts of kiss-me, 25 parts of centella, 20 parts of Ramulus euonymi, 20 parts of frutus cnidii, licorice 30 parts, 25 parts of radix rehmanniae recen, 30 parts of Radix Astragali.
Preferably, 20~30 parts of caulis bambusae in taenian of making a living is replaced in 10~20 parts of the bamboo juice.
Preferably, 25 parts of caulis bambusae in taenian of making a living is replaced in 15 parts of the bamboo juice.
The present invention also provides the preparation methods of the Chinese herb bath stain preparation, include the following steps:1) room temperature water logging is used Steep 20~80min of Chinese medicine material;2) material after the immersion is subjected to the first decoction, the first separation of solid and liquid, obtains first and decocts Boil liquid and first dregs of a decoction;First decoction is to change to be cooked by slow fire 25~35min after intense fire is fried boiling;3) by first dregs of a decoction and water Mixing carries out second and decocts, is separated by solid-liquid separation, and obtains the second decoction liquor;Described second decoct be change after intense fire is fried boiling be cooked by slow fire 15~ 25min;4) first decoction liquor is mixed with the second decoction liquor and obtains Chinese herb bath stain preparation.
Preferably, the amount of Chinese medicine material described in step 1) and water ratio is 1:(5~15).
Preferably, the amount of the second decoction water is 5~7 times of Chinese medicine material amount.
Beneficial effects of the present invention:The Chinese herb bath stain preparation for the treatment of eczema provided by the invention has harmonizing yingfen and weifen, wind-dispelling Dampness elimination, removing toxic substances promoting blood circulation, sterilization is anti-inflammatory, and the effect of slow excitation, antiallergic, sample combines, and the differentiation of disease is dialectical, is applied to anxious, sub-, chronic inclined Wet and heat type atopic eczema produces effects very prompt.It is normally applied Chinese herb bath stain preparation bath 1 to 3 rash of stain and disappears and itch only, 7 days skin The eliminations such as erythema is hot, festers effectively can cure or control the eczema at any position at 10 days or so;The Chinese herb bath stain preparation It is easy to use, it is not required to take orally, safe without toxic side effect.
Specific implementation mode
The present invention provides a kind of Chinese herb bath stain preparations for treating eczema, include the raw material of following parts by weight:Cassia twig 10~ 20 parts, 10~16 parts of elscholtiza, 25~35 parts of Radix Paeoniae Alba, 35~45 parts of dark plum, 10~20 parts of cicada slough, 15~25 parts of paniculate swallowwort, summer cypress 15~25 parts of son, 20~30 parts of dittany bark, raw 25~35 parts of radix scutellariae, 10~20 parts of bamboo juice, 15~25 parts of Fructus Forsythiae, oldenlandia diffusa 20~30 parts, 20~30 parts of nine inner bright, 25~35 parts of purslane, 20~30 parts of kiss-me, 20~30 parts of centella, Ramulus euonymi 15 ~25 parts, 15~25 parts of frutus cnidii, 25~35 parts of licorice, 20~30 parts of radix rehmanniae recen, 25~35 parts of Radix Astragali.
Preferably, include the raw material of following parts by weight:15 parts of cassia twig, 13 parts of elscholtiza, 20 parts of Radix Paeoniae Alba, 40 parts of dark plum, cicada slough 15 parts, 20 parts of paniculate swallowwort, 20 parts of the fruit of summer cypress, 25 parts of dittany bark, raw 30 parts of radix scutellariae, 15 parts of bamboo juice, 20 parts of Fructus Forsythiae, oldenlandia diffusa 25 parts, 25 parts of nine inner bright, 30 parts of purslane, 25 parts of kiss-me, 25 parts of centella, 20 parts of Ramulus euonymi, 20 parts of frutus cnidii, licorice 30 parts, 25 parts of radix rehmanniae recen, 30 parts of Radix Astragali.
In the present invention, the bamboo juice is also alternatively made a living caulis bambusae in taenian;The parts by weight of the raw caulis bambusae in taenian are 20~30 parts, preferably It is 25 parts.
In the present invention, the place of production of the elscholtiza is preferably Jiangxi;The place of production of the Radix Astragali is preferably the Inner Mongol;Described nine In the bright place of production be preferably Henan;The dark plum, kiss-me and the place of production of purslane are preferably Anhui;Except upper in the present invention State the commercially available medicinal material that other Chinese medicine materials outside Chinese medicine material use this field routine place of production.
The compatibility thinking of Chinese herb bath stain preparation of the present invention:From Traditional Chinese Medicine face card ask because when it is distinguishable be wind, or with Wind is haunted, and it is cold to press from both sides the dry folder of the wet folder of heat folder;Card positioning is examined with ying, wei, qi, xue and internal organs.To seek Wei Weiwei, wind folder is wet and folder heat is Cause, the wet discord battalion of wind-heat defends to distinguish, founds harmonizing yingfen and weifen, and wind dispelling is therapy by heresy.
The monarch compatibility principle and effect of heretofore described Chinese herb bath stain preparation:
Cassia twig in Chinese herb bath stain preparation of the present invention has warming meridian, and activate yang inducing diaphoresis, fluent to defend gas, elscholtiza sweating Inducing diaphoresis, Eradicates affix one's name to dampness elimination, the effect of inducing diuresis for removing edema.The elscholtiza smell is cool, and matter lightly floats again, and space between skin and muscles is let out in upper capable of opening, facilitaing lung gas, It is cold with Xie Biao up to fur;Lower energy sensible three is burnt, dredges wing evening, diuresis, to lead in inner water.
Elscholtiza in Chinese herb bath stain preparation of the present invention, according to《A supplement to augmented materia medica》Record has effects that following: " elscholtiza has thorough thorough lower work(, harnesses the river very prompt.Then Qinghua row that lung obtains and heat are under.Elscholtiza cures the wound heat, diuresis ... ".This hair Bright to be activated yang dampness elimination with the reinforcement that is harmonious of cassia twig, elscholtiza, strongly fragrant poison of dispelling of having a good sweat, external-open pore is by bandit.
Radix Paeoniae Alba picric acid in Chinese herb bath stain preparation of the present invention is slightly cold, and hardship is cool to expel the heat-evil, and holds back cloudy and battalion, nourishing battalion the moon. The present invention is mutually amounted to cassia twig, elscholtiza, Radix Paeoniae Alba three as monarch drug in a prescription, has the effect of misery, receipts dissipate, harmonizing yingfen and weifen, Yin Yang balancing.
Cicada slough wind-dispelling heat-dissipating in Chinese herb bath stain preparation of the present invention, evacuate pathogenic wind is antipruritic, kind to control wind no matter wind in exogenous wind Card;The paniculate swallowwort wind-dispelling removing toxicity for detumescence, bamboo juice or raw caulis bambusae in taenian (generation) clearing heat and eliminating phlegm, obtain cassia twig, elscholtiza reaches, and no network is obstructed, Wash phlegm and dredge network, osmanthus skill, elscholtiza is helped to open the poison of space between skin and muscles, tune freely defends the strongly fragrant of gas, for control sore to agent;The dark plum acid is sweet Change cloudy increase to seek, helps the power of Radix Paeoniae Alba and battalion;The Fructus Forsythiae, kiss-me, oldenlandia diffusa, centella, purslane, radix rehmanniae recen, terrible arrow Plumage clearing heat and promoting diuresis, cooling and activating blood, purging intense heat and detonicating.Above-mentioned ten simply medicine altogether be ministerial drug, phase 5 reinforce monarch drug in a prescription and battalion adjust defends, let out strongly fragrant The effect of poison, anti-inflammation detumescence, relieving itching.
The heretofore described fruit of summer cypress, dittany bark, frutus cnidii, radix scutellariae, nine inner bright expelling wind and clearing away heat, removing toxic substances dehumidifying, enhancing are gone Seek it is weak give birth to hot and suffocating, dry to defend strongly fragrant institute stagnant wet, and is adjutant.
Heretofore described Radix Glycyrrhizae coordinating the drug actions of a prescription, purging intense heat and detonicating, raw Radix Astragali invigorating qi for consolidating superficies, promoting pus discharge and tissue regeneration, inducing diuresis for removing edema;For Make medicine.
Chinese herb bath stain preparation provided by the invention has anti-inflammatory, sterilization, and antianaphylaxis reagentia, clinical observation can be bright Aobvious buffering anaphylactogen excitation effect, releases special (allergy) property eczema, and clinical observation bath stain agent is fully recovered patient, again by When quick primary stimuli, swash promise repeatedly relatively slightly, disappear quickly after Chinese herb bath stain preparation described in repeated application, in addition, the present invention provides Chinese herb bath stain preparation also have the function of whitening and moistening skin.
Heretofore described Chinese herb bath stain preparation, transdermal penetration administration;The action principle and advantage of transdermal penetration administration: Drug is directed through percutaneous absorption:Skin is the maximum organ of human body, in addition to having the protective effect for resisting exopathogen invasion, is also divided The multiple functions such as secrete, absorb, permeating, draining, feeling.Secondly, the absorption infiltration of skin is related with humidity, contains in Chinese herb bath stain agent There are hydrone, humidity to have enhancing disease, card that prescription medicine is combined to melt with bath stain application warm liquid medicine (37~38 DEG C) double action again It is integrated bath stain, Chinese herb bath stain preparation of the present invention contains the distinctive active ingredient of Chinese medicine, such as sesquiterpene, glucoside, sugar Class, glucin, a variety of amino acid, a variety of human bodies it is necessary trace element, bouvardin and have strong aromatic ketone, aldehyde, phenol, The volatility oily mater such as alcohol;Under the action of the Chinese herb bath stain preparation is with warm (37~38 DEG C), make capillary of skin Expansion, the medicine ion in the Chinese herb bath stain preparation be directed through cuticula transhipment (comprising intracellular, iuntercellular diffusion) and Epidermis transhipment absorbs, and drug is transported into blood circulation by multipath, accelerates drug absorption and utilization, drug absorption process Compared with average rate, stable state diffusion, pharmaceutical quantities uniform increments, space between skin and muscles is goed deep into the relative constant radiation of concentration, internal organs play drug effect.In the present invention The bath stain time of the Chinese herb bath stain preparation is preferably 15~20min.
The present invention also provides the preparation methods of the Chinese herb bath stain preparation, include the following steps:1) room temperature water logging is used Steep 20~80min of Chinese medicine material;2) material after the immersion is subjected to the first decoction, the first separation of solid and liquid, obtains first and decocts Boil liquid and first dregs of a decoction;First decoction is to change to be cooked by slow fire 25~35min after intense fire is fried boiling;3) by first dregs of a decoction and water Mixing carries out second and decocts, is separated by solid-liquid separation, and obtains the second decoction liquor;Described second decoct be change after intense fire is fried boiling be cooked by slow fire 15~ 25min.4) first decoction liquor is mixed with the second decoction liquor and obtains Chinese herb bath stain preparation.
In the present invention, the amount of the Chinese medicine material and water is than preferably 1:(5~15), more preferably 1:(8~12). The time of the immersion is preferably 30~70min in the present invention.Heretofore described immersion act as making by impregnating Chinese medicine material softens, Chinese medicine material water swelling, the close cold water composition exudation in traditional Chinese medicine ingredients;Avoid starch, protein simultaneously The more Chinese medicine material of content is directly got angry decoction, the starch gelatinization on Chinese medicine material surface, protein coagulating, blocks Chinese medicine material The capillary channel on surface, active ingredient are not easy fried, influence curative effect of medication.
The present invention obtains herbal medicine immersion liquid after steeping, after decocting the herbal medicine immersion liquid, is separated by solid-liquid separation decoction liquor, collects Liquid phase component obtains Chinese herb bath stain preparation.In the present invention, described decoct includes:Material after the immersion is carried out first to decoct It boils, the first separation of solid and liquid, obtains the first decoction liquor and first dregs of a decoction;First dregs of a decoction are mixed with water progress second decoct, It is separated by solid-liquid separation, obtains the second decoction liquor;First decoction liquor is mixed with the second decoction liquor and obtains Chinese herb bath stain preparation.
In the present invention, first decoction is cooked by slow fire 25~35min after preferably boiling by intense fire;It is heretofore described The time being cooked by slow fire is preferably 28~32min, more preferably 30min.
The present invention carries out first after being decocted described first and is separated by solid-liquid separation, and collects the first decoction liquor and first dregs of a decoction;At this First is separated by solid-liquid separation the preferably method progress using filtering described in invention;The filtering preferably uses filtered through gauze.
The present invention mixes progress second with water after obtaining first dregs of a decoction, by first dregs of a decoction and decocts.In this hair In bright, the quality of the second decoction water is preferably 5~7 times of Chinese medicine material quality, more preferably 5.5~6.5 times. Heretofore described second decoction is to be cooked by slow fire 15~25min after boiling by intense fire.It is cooked by slow fire in heretofore described second decoction Time be preferably 18~23min, more preferably 20min.
The present invention is separated by solid-liquid separation after being decocted described second, obtains the second decoction liquor and second dregs of a decoction.In the present invention In, the separation of solid and liquid is preferably carried out using the method for filtering;The filtering preferably uses filtered through gauze.
The present invention mixes with the second decoction liquor after obtaining second decoction liquor, by first decoction liquor and obtains Chinese medicine Bathe stain preparation.
In the present invention, the Chinese herb bath stain preparation can also be prepared by automatic two-decoction decocting machine.In this hair Automatic two-decoction decocting machine described in bright is commercial product.The present invention is preparing the Chinese herb bath using the automatic two-decoction decocting machine When stain preparation, the Chinese medicine material is placed in automatic two-decoction decocting machine, the water of 5~15 times of addition Chinese medicine material quality impregnates 1~3 After hour, start automatic two-decoction decocting machine and decoct, rear filtering obtains the Chinese herb bath stain preparation.
The Chinese herb bath stain preparation can be used directly in Chinese herb bath stain preparation of the present invention when in use, also can will be described Chinese herb bath stain preparation uses after being mixed with warm water;The temperature of the bath stain agent is preferably 33~38 DEG C;The warm water and Chinese herb bath The volume ratio of stain preparation is preferably (2~6):1.
With reference to embodiment to a kind of Chinese herb bath stain preparation for treating eczema provided by the invention and preparation method thereof into Row detailed description, but they cannot be interpreted as limiting the scope of the present invention.
Embodiment 1
Chinese medicine material:Cassia twig 15g, elscholtiza 13g, Radix Paeoniae Alba 30g, dark plum 40g, cicada slough 15g, paniculate swallowwort 20g, fruit of summer cypress 20g, Dittany bark 25g, raw radix scutellariae 30g, bamboo juice 15g, Fructus Forsythiae 20g, oldenlandia diffusa 25g, nine inner bright 25g, purslane 30g, kiss-me 25g, centella 25g, Ramulus euonymi 20g, frutus cnidii 20g, licorice 30g, radix rehmanniae recen 25g, Radix Astragali 30g.
It is decocted after above-mentioned Chinese medicine material is mixed immersion 30min with the water of 4000ml;It boils by intense fire up to after 100 DEG C, Change and is cooked by slow fire 30min and can consider liquid medicine and obtain 2500ml;Second of decoction of row again, is put into tap water 3000ml, boils by intense fire 100 DEG C, change and be cooked by slow fire 20min, then liquid is considered and 2500ml, two liquid about 5000ml mixing of boiling medicine obtain Chinese herb bath stain system Agent.
Embodiment 2
Cassia twig 15g, elscholtiza 13g, Radix Paeoniae Alba 30g, dark plum 40g, cicada slough 15g, paniculate swallowwort 20g, fruit of summer cypress 20g, dittany bark 25g, raw radix scutellariae 30g, raw caulis bambusae in taenian 25g, Fructus Forsythiae 20g, oldenlandia diffusa 25g, nine inner bright 25g, purslane 30g, kiss-me 25g, Centella 25g, Ramulus euonymi 20g, frutus cnidii 20g, licorice 30g, radix rehmanniae recen 25g, Radix Astragali 30g.
It is decocted after above-mentioned Chinese medicine material is mixed immersion 60min with the water of 5000ml;It boils by intense fire up to after 100 DEG C, Change and is cooked by slow fire 30min and can consider liquid medicine and obtain 2500ml;Second of decoction of row again, is put into tap water 3000ml, boils by intense fire 100 DEG C, change and be cooked by slow fire 20min, then liquid is considered and 2500ml, two liquid about 5000ml mixing of boiling medicine obtain Chinese herb bath stain system Agent.
Embodiment 3
Chinese medicine material:Cassia twig 16g, elscholtiza 15g, Radix Paeoniae Alba 29g, dark plum 42g, cicada slough 14g, paniculate swallowwort 21g, fruit of summer cypress 19g, Dittany bark 26g, raw radix scutellariae 28g, bamboo juice 16g, Fructus Forsythiae 18g, oldenlandia diffusa 23g, nine inner bright 24g, purslane 32g, kiss-me 22g, centella 27g, Ramulus euonymi 19g, frutus cnidii 22g, licorice 34g, radix rehmanniae recen 24g, Radix Astragali 34g.
It is decocted after above-mentioned Chinese medicine material is mixed immersion 50min with the water of 5000ml;It boils by intense fire up to after 100 DEG C, Change and is cooked by slow fire 30min and can consider liquid medicine and obtain 2500ml;Second of decoction of row again, is put into tap water 3000ml, boils by intense fire 100 DEG C, change and be cooked by slow fire 20min, then liquid is considered and 2500ml, two liquid about 5000ml mixing of boiling medicine obtain Chinese herb bath stain system Agent.
Embodiment 4
Chinese medicine material:Cassia twig 15g, elscholtiza 13g, Radix Paeoniae Alba 30g, dark plum 40g, cicada slough 15g, paniculate swallowwort 20g, fruit of summer cypress 20g, Dittany bark 25g, raw radix scutellariae 30g, bamboo juice 15g, Fructus Forsythiae 20g, oldenlandia diffusa 25g, nine inner bright 25g, purslane 30g, kiss-me 25g, centella 25g, Ramulus euonymi 20g, frutus cnidii 20g, licorice 30g, radix rehmanniae recen 25g, Radix Astragali 30g.
Above-mentioned Chinese medicine material is placed in automatic two-decoction decocting machine, accurately upper water 5000ml, after impregnating 2 hours, started automatic After two-decoction decocting machine decocts, it is 4800ml Chinese herb bath stain preparations that filtering, which obtains volume,.
Embodiment 5
5.1. the standard of case is selected
5.1.1. infant's atopic eczema, exudative type eczema, drying type eczema, adult's eczema, eczema mammae, scrotum are wet Rash, pudendum eczema, eczema of anus, hand eczema, leg foot eczema, eczema fissum.
5.2.2 erythema, red pimple, acute pruritus, water sore, sepage, yellow water be dripping, rotten to the corn, incrustation, infiltration and chap,
5.3.3. anxious, sub-, chronic eczema is partially wet and heat type.
Patient with above-mentioned 3 symptoms, the alternatively standard of case, give and treat.
5.2. diagnostic criteria:
With erythema, red pimple, acute pruritus, water sore, sepage, yellow water be dripping, rotten to the corn, incrustation, infiltration and chap, seborrhea Property eczema, acute urticaria, it is partially wet to anxious, slow atopic eczema with heat type eczema special efficacy, also have to various pruituses etc. aobvious Effect.The selecting of case selects those patients as observation object, and how is their state of an illness, and this product is passed through in Zhang Anlin clinical practices Developed on the basis of proved recipe, to originally treatment infant eczema on the basis of further expand and adult acute's eczema, fat Property eczema, acute urticaria, the acute and chronic eczema of overflowing are partially wet with heat type such as erythema, red pimple, acute pruritus, water sore, sepage, Huang Water wet and heat type eczema that is dripping, rotten to the corn, forming a scab, infiltrate and chap also has special efficacy, also has to various pruituses effective.It is wet Rash, fash have diversity, acute pruritus, easily recurrence the features such as, which is common frdquently encountered disease, account for the 20 of Dermatology Outpatient Department amount to 50%.
5.3. therapeutic scheme
Bathe stain method:Adapt to whole body or locality eczema etc..With 37 DEG C or so of 1 Chinese herb bath stain preparations 2000 of embodiment~ 2500ml is added warm water and carries out full bath 15~20min of stain in right amount, 2 times a day.
Application method:Adapt to locality eczema etc..Absorbent cotton paper is dipped in into medicine and sticks on affected part, can up be added several times after absorbent cotton paper is dry Liquid, the available absorbent cotton paper dip in liquid medicine of rotten to the corn open wound stick.
Scouring method:Adapt to limitation eczema etc..Absorbent cotton paper dip in liquid medicine is wiped repeatedly affected part for several times.
Hip bath method:It is suitble to vulva, crissum, buttocks eczema.With 37 DEG C or so of 1 Chinese herb bath stain preparations 2000 of embodiment~ 2500ml is added warm water and carries out full hip bath 30min in right amount, 2 times a day.
5.5. efficacy assessment standard
5.5.1. curing:Through bathing stain, applying, wipe, erythema, red pimple, itch, water sore, sepage, yellow water be dripping, rotten to the corn, knot Scab, infiltration and chap etc. are subsided completely, can be left pigmentation (chronic eczema person, stains of bathing can disappear) more and not itched.
5.5.2. it significantly improves:Through bathing stain, applying, wipe, erythema, red pimple, itch, water sore, sepage, yellow water be dripping, it is rotten to the corn, Incrustation, infiltration and chap etc. are apparent to subside, and can leave pigmentation (chronic eczema person, stains of bathing can disappear) more and not itch.
5.5.3. according to the state of an illness, same disease treatment it is the sooner the better, times for spraying is fewer, and the time dragged longer medication is just Longer, the time for the treatment of is also longer, but can cure.
5.5.5. erythema, red pimple, acute pruritus, water sore, sepage, yellow water be dripping, rotten to the corn, incrustation, infiltration and chap etc. Subside, epidermis incrustation falls off, and all better, livid purple, extravasated blood disappears the surface of a wound.
5.5. statistical procedures
Infant eczema, exudative type eczema, drying type eczema, adult's eczema, eczema mammae, the moon are selected according to above-mentioned standard Capsule eczema, pudendum eczema, eczema of anus, hand eczema, leg foot eczema, eczema fissum, erythema, red pimple, itch are acute Strong, water sore, sepage, yellow water be dripping, rotten to the corn, incrustation, infiltration and the acute eczema of chap, seborrheic eczema, acute urticaria, it is special 1083 of the partially wet case treatment standard with heat type of anisotropic eczema use by locality Duo Jia large hospitals dept. of dermatology more before going to a doctor Kind oral administration and externally Chinese and western drugs fail to respond to any medical treatment and carry out this outpatient service and receive present invention bath stain liquid treatment.378 people of male, female in 1083 Property 705 people, age reckling 21 days, the maximum 84 years old, birth 1 month to 6 months 367,7 months to 12 months 430,13 To 19 months 286, average 6.5 years old;The course of disease most elder 30 years, most short person 3 days are 120 days average.It is counted such as 1 course for the treatment of within 7 days Under:980 people are cured in 1083, are improved 103, and total effective rate 100.0%, fast person bathes 1 i.e. effective, slow person's bath stain 3 times of stain It shows, controls within average 3 days, cure within 1 week, end finds there is any toxic side effect during medication, securely and reliably.Before medical The effect of various Chinese and western drugs with that on the one hand compared with P values it is equal<0.001.
By above-described embodiment it is found that Chinese herb bath stain preparation provided by the invention, Clinical results are shown, the Chinese herb bath Stain preparation for treating baby atopic eczema, exudative type eczema, drying type eczema, adult's eczema, eczema mammae, eczema of scrotum, female Vaginal eczema, eczema of anus, hand eczema, leg foot eczema, eczema fissum, erythema, acute pruritus, water sore, are oozed red pimple Liquid, yellow water are dripping, rotten to the corn, incrustation, infiltrate and chap, and anxious, sub-, chronic (seborrheic eczema, acute urticaria, chronic eczema are anxious Property stage of attack) partially wet have significant curative effect with heat type eczema etc..Its symptom complex curative effect total effective rate is respectively 100.0%.It is comprehensive Compare Chinese herb bath stain preparation bath stain treatment specificity it is partially wet with hot eczema is curative for effect, it is rapid to take effect, it is easy to use, and It does not find obvious adverse reaction in application process, have no toxic side effect, most of patient reaction also has the effect of whitening and moistening skin.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered It is considered as protection scope of the present invention.

Claims (7)

1. a kind of Chinese herb bath stain preparation for treating eczema, includes the raw material of following parts by weight:10~20 parts of cassia twig, elscholtiza 10~16 Part, 25~35 parts of Radix Paeoniae Alba, 35~45 parts of dark plum, 10~20 parts of cicada slough, 15~25 parts of paniculate swallowwort, 15~25 parts of the fruit of summer cypress, dittany 20~30 parts of skin, raw 25~35 parts of radix scutellariae, 10~20 parts of bamboo juice, 15~25 parts of Fructus Forsythiae, 20~30 parts of oldenlandia diffusa, nine inner bright 20~30 parts, 25~35 parts of purslane, 20~30 parts of kiss-me, 20~30 parts of centella, 15~25 parts of Ramulus euonymi, frutus cnidii 15 ~25 parts, 25~35 parts of licorice, 20~30 parts of radix rehmanniae recen, 25~35 parts of Radix Astragali.
2. Chinese herb bath stain preparation according to claim 1, which is characterized in that include the raw material of following parts by weight:Cassia twig 15 Part, 13 parts of elscholtiza, 20 parts of Radix Paeoniae Alba, 40 parts of dark plum, 15 parts of cicada slough, 20 parts of paniculate swallowwort, 20 parts of the fruit of summer cypress, 25 parts of dittany bark, raw Huang 30 parts of a kind of reed mentioned in ancient books, 15 parts of bamboo juice, 20 parts of Fructus Forsythiae, 25 parts of oldenlandia diffusa, 25 parts of nine inner bright, 30 parts of purslane, 25 parts of kiss-me, accumulated snow 25 parts of grass, 20 parts of Ramulus euonymi, 20 parts of frutus cnidii, 30 parts of licorice, 25 parts of radix rehmanniae recen, 30 parts of Radix Astragali.
3. Chinese herb bath stain preparation according to claim 1, which is characterized in that caulis bambusae in taenian of making a living is replaced in 10~20 parts of the bamboo juice 20~30 parts.
4. Chinese herb bath stain preparation according to claim 2, which is characterized in that caulis bambusae in taenian 25 of making a living is replaced in 15 parts of the bamboo juice Part.
5. the preparation method of the Chinese herb bath stain preparation described in Claims 1 to 4 any one, includes the following steps:
1) 20~80min of Chinese medicine material is impregnated with normal-temperature water;
2) material after the immersion is subjected to the first decoction, the first separation of solid and liquid, obtains the first decoction liquor and first dregs of a decoction;Institute It is to change to be cooked by slow fire 25~35min after intense fire is fried boiling to state the first decoction;
3) first dregs of a decoction are mixed to progress second to decoct, be separated by solid-liquid separation with water, obtain the second decoction liquor;Described second decocts Change after being fried boiling for intense fire and is cooked by slow fire 15~25min;
4) first decoction liquor is mixed with the second decoction liquor and obtains Chinese herb bath stain preparation.
6. preparation method according to claim 5, which is characterized in that the amount of Chinese medicine material described in step 1) and water ratio is 1:(5~15).
7. preparation method according to claim 5, which is characterized in that the amount of the secondary decoction water is Chinese medicine material amount 5~7 times.
CN201810421029.5A 2018-05-04 2018-05-04 A kind of Chinese herb bath stain preparation and preparation method thereof for treating eczema Pending CN108310255A (en)

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