CN107913346A - A kind of external used medicine liniment for dispelling the scales of skin that peel off and its preparation method and application - Google Patents
A kind of external used medicine liniment for dispelling the scales of skin that peel off and its preparation method and application Download PDFInfo
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- CN107913346A CN107913346A CN201710237505.3A CN201710237505A CN107913346A CN 107913346 A CN107913346 A CN 107913346A CN 201710237505 A CN201710237505 A CN 201710237505A CN 107913346 A CN107913346 A CN 107913346A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A61K9/08—Solutions
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Abstract
The invention belongs to pharmaceutical technology field, and in particular to a kind of external used medicine liniment for dispelling the scales of skin that peel off and its preparation method and application, the raw material composition and dosage that the active ingredient for the external used medicine liniment that the scales of skin that peel off is dispelled described in every 1000ml is made are：6.0~7.0g of ginseng, 6.0~7.0g of prepared fleece flower root, 6.0~7.0g of Angelica sinensis, 5.0~6.0g of Ligusticum wallichii, 5.0~6.0g of the radix paeoniae rubrathe, 5.0~6.0g of rhizoma anemarrhenae, windproof 5.0~6.0g, 6.4~7.0g of pseudo-ginseng, 5.0~6.0g of peppermint, 450~550ml of ethanol, 450~550ml of water.The present invention solves the defects of existing treatment ichthyosis method.
Description
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of external used medicine liniment for dispelling the scales of skin that peel off and preparation method thereof
And application.
Background technology
At present, dyskeratosis skin disease is caused by the deficiency of liver-yin and kidney-yin and inherent cause, is mainly shown as dry skin, companion
There is fish scale-shaped furfur, multilinear heredity factor causes epidermal cell proliferation and disdifferentiation, causes cell Proliferation increase and/or cell to take off
Fall to reduce, it is on the rise in recent years, the physical and mental health of people is drastically influence, causes countries in the world extensively note that grinding one after another
Study carefully and capture such a recalcitrant dermal disease for endangering human health, but without specific medicament and the side for preferably treating the disease
Method.
At present, the symptom is mainly by relief of symptoms such as Western medicine product such as carbamide ointments, and medical field is usually using vitamin
A, 13- are along the outer liniment of the medicine such as vitamin A acid, the spirit of silver bits or methotrexate, urea frost, vitamin A acid, corticosteroid hormone, treatment
This kind of disease, its curative effect do not make us pleasing oneself, it is difficult to cure, high recurrence rate, long-time service can cause decalcification, alopecia etc. no
Good reaction, has human liver, kidney and intelligence very big infringement.
The content of the invention
The present invention seeks to：A kind of external used medicine liniment for dispelling the scales of skin that peel off is aimed to provide, for solving existing treatment fish scale
The defects of sick technical method, which exists, to be difficult to cure, and high recurrence rate, long-time service can cause the adverse reactions such as decalcification, alopecia, to people
Body liver, kidney and intelligence have the problem of very big infringement.
To realize above-mentioned technical purpose, the technical solution adopted by the present invention is as follows：
A kind of external used medicine liniment for dispelling fish scale bits, is made external used medicine liniment that the scales of skin that peel off is dispelled described in every 1000ml
The raw material of active ingredient forms and dosage is：
6.0~7.0g of ginseng, 6.0~7.0g of prepared fleece flower root, 6.0~7.0g of Angelica sinensis, 5.0~6.0g of Ligusticum wallichii, the radix paeoniae rubrathe 5.0~
6.0g, 5.0~6.0g of rhizoma anemarrhenae, windproof 5.0~6.0g, 6.4~7.0g of pseudo-ginseng, 5.0~6.0g of peppermint, 450~550ml of ethanol,
450~550ml of water.
Further limit, the raw material group of the active ingredient for the external used medicine liniment that fish scale bits are dispelled described in every 1000ml is made
Into and dosage be：
6.2~6.6g of ginseng, 6.2~6.8g of prepared fleece flower root, 6.2~6.8g of Angelica sinensis, 5.2~5.7g of Ligusticum wallichii, the radix paeoniae rubrathe 5.2~
5.8g, 5.2~5.8g of rhizoma anemarrhenae, windproof 5.2~5.8g, 6.5~6.9g of pseudo-ginseng, 5.2~5.8g of peppermint, 450~550ml of ethanol,
450~550ml of water.
Further limit, the raw material composition of the active ingredient for the external used medicine liniment that the scales of skin that peel off is dispelled described in every 1000ml is made
And dosage is：
6.2~6.5g of ginseng, 6.2~6.6g of prepared fleece flower root, 6.2~6.6g of Angelica sinensis, 5.3~5.6g of Ligusticum wallichii, the radix paeoniae rubrathe 5.2~
5.6g, 5.2~5.6g of rhizoma anemarrhenae, windproof 5.2~5.6g, 6.5~6.8g of pseudo-ginseng, 5.3~5.6g of peppermint, 450~550ml of ethanol,
450~550ml of water.
Further limit, the raw material composition of the active ingredient for the external used medicine liniment that the scales of skin that peel off is dispelled described in every 1000ml is made
And dosage is：
Ginseng 6.4g, prepared fleece flower root 6.3g, Angelica sinensis 6.4g, Ligusticum wallichii 5.4g, radix paeoniae rubrathe 5.4g, rhizoma anemarrhenae 5.4g, windproof 5.4g, three
Seven 6.6g, peppermint 5.4g, ethanol 500ml, water 500ml.
Further limit, the raw material composition of the active ingredient for the external used medicine liniment that the scales of skin that peel off is dispelled described in every 1000ml is made
And dosage is：
Ginseng 6.5g, prepared fleece flower root 6.4g, Angelica sinensis 6.5g, Ligusticum wallichii 5.6g, radix paeoniae rubrathe 5.6g, rhizoma anemarrhenae 5.6g, windproof 5.5g, three
Seven 6.8g, peppermint 5.5g, ethanol 500ml, water 500ml.
Each raw material pharmacological property in the active ingredient of the above-mentioned external used medicine liniment for dispelling fish scale bits is as follows：
Ginseng：Reinforce vital energy, veins takes off admittedly, reinforces the spleen to benefit the lung, and promotes the production of body fluid, and calms the nerves.To be taken off for physically weak, cold weak pulse of limb is insufficiency of the spleen
Deficiency of food, the deficiency syndrome of the lung are breathed with cough, injury thirst, Heat Diabetes, and prolonged illness void is thin, insomnia of palpitating with fear, impotence Gong Leng；Heart failure, it is cardiogenic to stop
Gram (pharmacopeia 2010 edition second)；
Prepared fleece flower root：Filling liver kidney, benefiting essence-blood, black beard and hair, strengthening the bones and muscles, for blood deficiency chlorosis, dizziness and tinnitus, poliosis,
Soreness and weakness of waist and knees, extremity numbness, under uterine bleeding band, chronic malaria body void；Hyperlipidemia (pharmacopeia 2010 edition second)；
Angelica sinensis：Sweet, acrid, warm, Return liver, the heart, the spleen channel, replenishing and activating blood, menstruction regulating and pain relieving, relax bowel (pharmacopeia 2010 editions second
Portion)；
Ligusticum wallichii：Blood-activating and qi-promoting, wind-expelling pain-stopping.Wet, the promoting blood circulation and stopping pain for tumbling and swelling, promote breath and open depression, method wind-dryness.Fall flutter it is swollen
Bitterly, arthralgia pain due to rheumatism.(pharmacopeia 2010 edition second)；
The radix paeoniae rubrathe：Analgesic, cool blood, detumescence.For the stagnant Amenorrhea of the stasis of blood, the accumulation of hernia lump in the abdomen, abdominal pain, hypochondriac pain, bleeding from five sense organs or subcutaneous tissue, discharging fresh blood stool, mesh
It is red, carbuncle swells.(pharmacopeia 2010 edition second)；
Rhizoma anemarrhenae：It is bitter, sweet, tremble with fear.Return lung, stomach, kidney channel.For clearing heat-fire, fluid dryness, osteopyrexia and fever, Heat Diabetes, intestines
Dry constipation.(pharmacopeia 2010 edition second)；
It is windproof：It is pungent, sweet, tepor.Return lung, bladder, liver, the spleen channel.For expelling pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, stops convulsion.(pharmacopeia
2010 editions second)；
Pseudo-ginseng：Hemostasis, antithrombotic, promote hematopoiesis, for dissipate stasis of blood hemostasis, detumescence ding-tong (pharmacopeia 2010 edition second)；
Peppermint：Acrid flavour, it is cool in nature；Return lung, Liver Channel；Delicate fragrance, which rises, to be dissipated, for wind-dispelling heat-dissipating, antiphlogistic antibacterial.
The present invention also provides it is a kind of dispel fish scale bits external used medicine liniment preparation method, comprise the following steps：
Step 1)：Weigh medicine material crushing
By the medicine material quality, medicine material is weighed, the medicine material weighed is ground into coarse powder；
Step 2)：Extract supernatant
By the medicine material for being ground into coarse powder in step 1) according to infusion process under tincture item, take the medicine for being ground into coarse powder former
Material is positioned in container with lid, adds 600ml ethanol and 600ml water, closed, is impregnated 5 days at room temperature, is extracted supernatant；
Step 3)：Collect filtrate
When the supernatant standing 24 that the middle extraction of step 2) is obtained is small, filtration, collects filtrate；
Step 4)：Adjust total amount to 1000ml mixings and obtain liniment
380ml ethanol is added in the filtrate being collected into step 3) or is mixed with 30% ethanol adjustment total amount to 1000ml
It is even, the external used medicine liniment for dispelling fish scale bits of the present invention is made.
The present invention also provides a kind of application of external used medicine liniment for dispelling the scales of skin that peel off in ichthyosis is treated.
The external used medicine liniment provided by the present invention for dispelling fish scale bits is brown color liquid, fragrant odour.
A kind of external used medicine liniment for dispelling fish scale bits provided by the invention, when in use, patient is first by liniment painting time
Whole body affected part, after ten minutes, patient, which enters in the hot water that temperature is about 40 DEG C, to be soaked 30 minutes, and Bian Pao sides are firmly anti-with wash towel
Multiple rubbing affected part, dries the water in affected part after bath, then with hand by liquid way all over affected part, about wear the clothes, directly enter after five minutes within second day
Water, coating after bath, method are same as above, once a day, continual in patient 8 days to adhere to using the liniment, can be removed the scales of skin that peel off, be grown
Fine hair, skin smooth.
The method have the benefit that：The prepared fleece flower root in the external used medicine liniment of fish scale bits is dispelled, kidney can be entered, is mended
Blood, adds essence, reinforces the kidney and receives gas；Ginseng, enters spleen, lung, the heart, reinforces vital energy and promote the production of body fluid；When being included into liver, enrich blood, invigorate blood circulation；Three's mutual reinforcement between is
With, you can with tonifying Qi with green blood, and whole body vim and vigour essence Tianjin can be commanded, interior nourishing the liver internal organs, outside up to skin, flourish flesh moisturizing；Strength is oozed
Thoroughly, sweat gland is activated, percutaneous and medicine, works rapid, directly dredge pore, promotes Skin Cell regeneration, and the scales of skin that peel off comes off naturally；Promoting blood circulation
Dredging collateral, dispels blood toxicity, complete treatment ichthyosis, comprehensively regulating physical function；It is nourishing liver and kidney, help essence and blood, strengthening spleen and tonifying lung,
Reduce recurrence.
Embodiment
In order to make those skilled in the art that the present invention may be better understood, with reference to embodiment to the technology of the present invention
Scheme further illustrates.
Embodiment 1
A kind of external used medicine liniment for dispelling fish scale bits of the present invention, is made the externally applied drug that the scales of skin that peel off is dispelled described in every 1000ml
The raw material of the active ingredient of composition liniment forms and dosage is：
Ginseng 6.4g；
Prepared fleece flower root 6.3g；
Angelica sinensis 6.4g；
Ligusticum wallichii 5.4g；
Radix paeoniae rubrathe 5.4g；
Rhizoma anemarrhenae 5.4g；
Windproof 5.4g；
Pseudo-ginseng 6.6g；
Peppermint 5.4g；
Ethanol 500ml；
Water 500ml.
A kind of preparation method for external used medicine liniment for dispelling fish scale bits that the present embodiment 1 also provides, comprises the following steps：
Step 1)：Weigh medicine material crushing
Weigh ginseng 6.4g processed, prepared fleece flower root 6.3g, Angelica sinensis 6.4g, Ligusticum wallichii 5.4g, radix paeoniae rubrathe 5.4g, rhizoma anemarrhenae 5.4g, windproof
5.4g, pseudo-ginseng 6.6g, peppermint 5.4g.Above-mentioned weighed medicine material is ground into coarse powder；
Step 2)：Extract supernatant
By the medicine material for being ground into coarse powder in step 1) according to infusion process under tincture item, take the medicine for being ground into coarse powder former
Material is positioned in container with lid, adds 500ml ethanol and 500ml water, closed, is impregnated 5 days at room temperature, is extracted supernatant；
Step 3)：Collect filtrate
When the supernatant standing 24 that the middle extraction of step 2) is obtained is small, filtration, collects filtrate；
Step 4)：Adjust total amount to 1000ml mixings and obtain liniment
480ml ethanol is added in the filtrate being collected into step 3) or is mixed with 30% ethanol adjustment total amount to 1000ml
It is even, the external used medicine liniment for dispelling the scales of skin that peel off of the present invention is made.
The present embodiment 1 also provides a kind of application of external used medicine liniment for dispelling fish scale bits in ichthyosis is treated.
It is brown color liquid, fragrant odour that what the present embodiment 1 was provided, which dispels the external used medicine liniment that fish scale is considered to be worth doing,.
A kind of external used medicine liniment for dispelling fish scale bits that the present embodiment 1 provides, when in use, patient first applies the liniment
All over whole body affected part, after five minutes, patient, which enters in the hot water that temperature is about 40 DEG C, to be soaked 30 minutes, and Bian Pao is exerted oneself on side with wash towel
Rubbing affected part repeatedly, dries the water in affected part after bath, then with hand by liquid way all over affected part, about wear the clothes after five minutes, second day patient
Water, coating after bath can directly be entered before applying liquid, method is same as above, once a day, continual in patient 8 days to adhere to using
Liniment, can remove the scales of skin that peel off, grow fine hair.Keep curative effect, can frequent bathing, apply the liniment.
Embodiment 2：
A kind of external used medicine liniment for dispelling fish scale bits of the present embodiment 2, is made and the outer of the scales of skin that peel off is dispelled described in every 1000ml
The raw material of the active ingredient of medication composition liniment forms and dosage is：
Ginseng 6.5g；
Prepared fleece flower root 6.4g；
Angelica sinensis 6.5g；
Ligusticum wallichii 5.6g；
Radix paeoniae rubrathe 5.6g；
Rhizoma anemarrhenae 5.6g；
Windproof 5.5g；
Pseudo-ginseng 6.8g；
Peppermint 5.5g；
Ethanol 500ml；
Water 500ml.
A kind of preparation method for external used medicine liniment for dispelling fish scale bits that the present embodiment 2 also provides, comprises the following steps：
Step 1)：Weigh medicine material crushing
Weigh ginseng 6.5g processed, prepared fleece flower root 6.4g, Angelica sinensis 6.5g, Ligusticum wallichii 5.6g, radix paeoniae rubrathe 5.6g, rhizoma anemarrhenae 5.6g, windproof
5.5g, pseudo-ginseng 6.8g, peppermint 5.5g.Above-mentioned weighed medicine material is ground into coarse powder；
Step 2)：Extract supernatant
By the medicine material for being ground into coarse powder in step 1) according to infusion process under tincture item, take the medicine for being ground into coarse powder former
Material is positioned in container with lid, adds 500ml ethanol and 500ml water, closed, is impregnated 5 days at room temperature, is extracted supernatant；
Step 3)：Collect filtrate
When the supernatant standing 24 that the middle extraction of step 2) is obtained is small, filtration, collects filtrate；
Step 4)：Adjust total amount to 1000ml mixings and obtain liniment
480ml ethanol is added in the filtrate being collected into step 3) or is mixed with 30% ethanol adjustment total amount to 1000ml
It is even, the external used medicine liniment for dispelling the scales of skin that peel off of the present invention is made.
The present embodiment 2 also provides a kind of application of external used medicine liniment for dispelling fish scale bits in ichthyosis is treated.
It is brown color liquid, fragrant odour that what the present embodiment 2 was provided, which dispels the external used medicine liniment that fish scale is considered to be worth doing,.
A kind of external used medicine liniment for dispelling fish scale bits that the present embodiment 2 provides, when in use, patient first applies the liniment
All over whole body affected part, after five minutes, patient, which enters in the hot water that temperature is about 40 DEG C, to be soaked 30 minutes, and Bian Pao is exerted oneself on side with wash towel
Rubbing affected part repeatedly, dries the water in affected part after bath, then with hand by liquid way all over affected part, about wear the clothes after five minutes, second day patient
Water, coating after bath can directly be entered before applying liquid, method is same as above, once a day, continual in patient 8 days to adhere to using
Liniment, can remove the scales of skin that peel off, grow fine hair, skin smooth.
Clinical data：
1st, case selection
Treatment ichthyosis liniment provided by the invention is in May, -2016 in March, 2014 by Zhengzhou, henan China column leucoderma doctor
Fish scale patient totally 21315 observes jointly in institute, Zhengzhou hospital of Hua Fu institutes of internal medicine, the first affiliated hospital of Zhengzhou University,
Wherein, fish scale patient totally 320 observes in May, -2016 in March, 2014 in Zhengzhou, henan Hua Zhu leucoderma hospital, and male 140
People, 180 people of women, case average age 45 years old, average onset months are 21.4 months before going to a doctor, average per fell before going to a doctor
Skin illness area accounts for whole skin 8.2%, and averagely everyone treats number of days 16.5 days after going to a doctor.
2nd, 1 external used medicine liniment treated ichthyosis of the present embodiment, when in use, patient first applies the liniment to suffer from all over whole body
Place, after five minutes, patient, which enters in the hot water that temperature is about 40 DEG C, soak 30 minutes, and Bian Pao sides are exerted oneself rubbing repeatedly with wash towel
Affected part, dries the water in affected part after bath, then with hand by liquid way all over affected part, about wear the clothes after five minutes, patient's erasing daily once, 8
It is heaven-made as a treatment course, continuously observe 10 courses for the treatment of.
3rd, efficacy determination
Effectively：Symptom disappearance 36%-69% is referred to as effective；
It is effective：Symptom disappearance 70%-94% is referred to as effective；
Cure：Symptom all disappears or disappears 95% referred above to healing；
It is invalid：Symptom disappearance 35% is hereinafter referred to as invalid.
4th, case packet and treatment results
Zhengzhou, henan Hua Zhu leucoderma hospital carries out two groups of therapeutic effect observations and its knot in May, -2016 in March, 2014
Fruit is as follows：
1 case observation of curative effect result of table
5th, case packet and treatment results are tested
(1) the use of 1 external used medicine liniment treated ichthyosis of the present embodiment, 21 people is treatment group, it is soft using 0.1% vitamin A acid
Cream treatment 21 people of ichthyosis is control group.
(2) case selection method：It is random to receive patient, the approximate patient's choosing of age-based, gender, period of disease, illness symptom
Select 42 people.
(3) case packet mode：Random Design is pressed completely, and case, 7 cases are successively arranged sequentially according to medical order
For a small group, according to random alignment table case load, treatment group and control group are assigned to.
(4) treatment group and each 21 people of control group number, only limit is applied with once two groups of medicine daily, and dosage is identical.
(5) course for the treatment of is observed：Two groups, with 7 days as one therapeutic course, are continuously observed 10 courses for the treatment of, visited once at random in more latter year.
(6) two groups of data compare efficacy analysis：
Table 1 tests case observation of curative effect result
The effective percentage for the treatment of group, cure rate and without side-effects, hence it is evident that higher than control group, the significant of two groups of difference.
Treatment group 21 produces appreciable results after having medication three days, control group without this effect phenomenon, treatment group's efficiently individual quantity higher than pair
According to group 33.3%, the effective number for the treatment of group is higher than control group 42.9%, and treatment group cures number and is higher than control group 19.0%, treats
Group has 28.57% people to produce slight side effect without side effect, control group is produced.
In the present embodiment, the prepared fleece flower root in the external used medicine liniment of the scales of skin that peel off is dispelled, walnut kernel, can enter kidney, enrich blood, add
Essence, reinforces the kidney and receives gas；Panax ginseng and campanumaea pilosula, enters spleen, lung, the heart, reinforces vital energy and promote the production of body fluid；When backing into liver, enrich blood, invigorate blood circulation；Three's mutual reinforcement between is use,
Can tonifying Qi with green blood, and whole body vim and vigour essence Tianjin can be commanded, interior nourishing the liver internal organs, outside up to skin, flourish flesh moisturizing；Strong osmotic,
Sweat gland is activated, percutaneous and medicine, works rapid, directly dredge pore, promotes Skin Cell regeneration, and the scales of skin that peel off comes off naturally；Promoting blood circulation is logical
Network, dispels blood toxicity, complete treatment ichthyosis, comprehensively regulating physical function；Nourishing liver and kidney, help essence and blood, strengthening spleen and tonifying lung, subtracts
Few recurrence.
The merely exemplary explanation the principle of the present invention of above-described embodiment and its effect, not for the limitation present invention.It is any ripe
Know the personage of this technology all can carry out modifications and changes under the spirit and scope without prejudice to the present invention to above-described embodiment.Cause
This, all those of ordinary skill in the art without departing from disclosed spirit with being completed under technological thought
All equivalent modifications or change, should by the present invention claim be covered.
Claims (7)
- A kind of 1. external used medicine liniment for dispelling fish scale bits, it is characterised in that：The external application that the scales of skin that peel off is dispelled described in every 1000ml is made The raw material of the active ingredient of medicine liniment forms and dosage is：6.0~7.0g of ginseng, 6.0~7.0g of prepared fleece flower root, 6.0~7.0g of Angelica sinensis, 5.0~6.0g of Ligusticum wallichii, the radix paeoniae rubrathe 5.0~ 6.0g, 5.0~6.0g of rhizoma anemarrhenae, windproof 5.0~6.0g, 6.4~7.0g of pseudo-ginseng, 5.0~6.0g of peppermint, 450~550ml of ethanol, 450~550ml of water.
- A kind of 2. external used medicine liniment for dispelling fish scale bits according to claim 1, it is characterised in that：Every 1000ml is made The raw material of the active ingredient of the external used medicine liniment for dispelling fish scale bits forms and dosage is：6.2~6.6g of ginseng, 6.2~6.8g of prepared fleece flower root, 6.2~6.8g of Angelica sinensis, 5.2~5.7g of Ligusticum wallichii, the radix paeoniae rubrathe 5.2~ 5.8g, 5.2~5.8g of rhizoma anemarrhenae, windproof 5.2~5.8g, 6.5~6.9g of pseudo-ginseng, 5.2~5.8g of peppermint, 450~550ml of ethanol, 450~550ml of water.
- A kind of 3. external used medicine liniment for dispelling the scales of skin that peel off according to claim 1, it is characterised in that：Every 1000ml institutes are made State the active ingredient for the external used medicine liniment for dispelling the scales of skin that peel off raw material composition and dosage be：6.2~6.5g of ginseng, 6.2~6.6g of prepared fleece flower root, 6.2~6.6g of Angelica sinensis, 5.3~5.6g of Ligusticum wallichii, the radix paeoniae rubrathe 5.2~ 5.6g, 5.2~5.6g of rhizoma anemarrhenae, windproof 5.2~5.6g, 6.5~6.8g of pseudo-ginseng, 5.3~5.6g of peppermint, 450~550ml of ethanol, 450~550ml of water.
- A kind of 4. external used medicine liniment for dispelling the scales of skin that peel off according to claim 1-3 any one, it is characterised in that：It is made The raw material composition and dosage of active ingredient per the external used medicine liniment that the scales of skin that peel off is dispelled described in 1000ml be：Ginseng 6.4g, prepared fleece flower root 6.3g, Angelica sinensis 6.4g, Ligusticum wallichii 5.4g, radix paeoniae rubrathe 5.4g, rhizoma anemarrhenae 5.4g, windproof 5.4g, pseudo-ginseng 6.6g, peppermint 5.4g, ethanol 500ml, water 500ml.
- A kind of 5. external used medicine liniment for dispelling the scales of skin that peel off according to claim 1-3 any one, it is characterised in that：It is made The raw material composition and dosage of active ingredient per the external used medicine liniment that the scales of skin that peel off is dispelled described in 1000ml be：Ginseng 6.5g, prepared fleece flower root 6.4g, Angelica sinensis 6.5g, Ligusticum wallichii 5.6g, radix paeoniae rubrathe 5.6g, rhizoma anemarrhenae 5.6g, windproof 5.5g, pseudo-ginseng 6.8g, peppermint 5.5g, ethanol 500ml, water 500ml.
- 6. a kind of preparation method of external used medicine liniment for dispelling the scales of skin that peel off as described in claim 1-5 any one, including with Lower step：Step 1)：Weigh medicine material crushingBy the medicine material quality, medicine material is weighed, the medicine material weighed is ground into coarse powder；Step 2)：Extract supernatantBy the medicine material for being ground into coarse powder in step 1) according to infusion process under tincture item, the medicine material for being ground into coarse powder is taken to put It is placed in container with lid, adds 600ml ethanol and 600ml water, it is closed, impregnate 5 days at room temperature, extract supernatant；Step 3)：Collect filtrateWhen the supernatant standing 24 that the middle extraction of step 2) is obtained is small, filtration, collects filtrate；Step 4)：Adjust total amount to 1000ml mixings and obtain linimentIn the filtrate being collected into step 3) add 380ml ethanol or with 30% ethanol adjust total amount to 1000ml mixing, The external used medicine liniment for dispelling fish scale bits of the present invention is made.
- 7. a kind of external used medicine liniment for dispelling fish scale bits as described in claim 1-5 any one is applied to treatment fish scale Disease.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106256370A (en) * | 2015-06-19 | 2016-12-28 | 吴晓敏 | A kind of external used medicine liniment dispelling squama and its preparation method and application |
| CN109908293A (en) * | 2019-03-18 | 2019-06-21 | 北京美肤鱼鳞病研究院 | A kind of Chinese medicine composition of fumigation treatment ichthyosis |
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| CN106256370A (en) * | 2015-06-19 | 2016-12-28 | 吴晓敏 | A kind of external used medicine liniment dispelling squama and its preparation method and application |
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2017
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106256370A (en) * | 2015-06-19 | 2016-12-28 | 吴晓敏 | A kind of external used medicine liniment dispelling squama and its preparation method and application |
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| 东更道小老板: "本草净玉搽剂鱼鳞病专用中药，去除腿上的鳞屑白皮", 《舜网济南社区》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106256370A (en) * | 2015-06-19 | 2016-12-28 | 吴晓敏 | A kind of external used medicine liniment dispelling squama and its preparation method and application |
| CN109908293A (en) * | 2019-03-18 | 2019-06-21 | 北京美肤鱼鳞病研究院 | A kind of Chinese medicine composition of fumigation treatment ichthyosis |
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