CN107929624A - A kind of ointment for treating tinea pedis and preparation method thereof - Google Patents

A kind of ointment for treating tinea pedis and preparation method thereof Download PDF

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CN107929624A
CN107929624A CN201711133378.9A CN201711133378A CN107929624A CN 107929624 A CN107929624 A CN 107929624A CN 201711133378 A CN201711133378 A CN 201711133378A CN 107929624 A CN107929624 A CN 107929624A
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parts
ointment
acid
stemona
shaggy
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王衡山
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/22Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
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  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of ointment for treating tinea pedis, include the raw material of following parts by weight:5~15 parts of kuh-seng, 6~18 parts of the root bark of shaggy-fruited dittany, 5~18 parts of salicylic acid, 15~30 parts of the tuber of stemona, 3~12 parts of benzoic acid, 8~20 parts of boric acid, 6~18 parts of alumen, 20~60 parts of glycerine.The invention also discloses its preparation method:1) kuh-seng, the root bark of shaggy-fruited dittany, the tuber of stemona are first processed into coarse powder, added water to cook twice, every time 2 it is small when, collecting decoction, filtration, filtrate is condensed into medicinal extract;2) salicylic acid, benzoic acid, boric acid, alumen are processed into fine powder with medicinal herb grinder, cross 120 mesh sieves;3) medicinal extract obtained by step 1) is added in fine powder obtained by step 2), and adds qs glycerin at the same time, stirred evenly with mixer, to soft or hard appropriateness both can, be stored in shady place with glass or plastic containers.Cure rate of the present invention is high, have no adverse reaction, recurrence rate is low, mitigates the symptoms such as itch after smearing at once, mitigates patient suffering.

Description

A kind of ointment for treating tinea pedis and preparation method thereof
Technical field
The present invention relates to a kind of ointment for treating tinea pedis and preparation method thereof.
Background technology
Tinea pedis, also known as athlete's foot, scientific name are a kind of common, multiple, infectious skin diseases, infect fungi tinea pedis It is caused.Traditional Chinese medicine thinks that the formation of tinea pedis has two aspects of internal cause and external cause, and internal cause is damp heat in the spleen and the stomach bet, is stranded in foot Portion must not declare logical;External cause, which is wind, wet, hot, cold poison is evil attacks within foot skin, and corrosion failure skin, loses skin imperial Outer function, so as to cause disease pest invasion to form.Tinea pedis is all popular in the whole world, especially in subtropical and tropical zones more To be universal.In China, the incidence of tinea pedis is also very high, more common with southern each province.
Though tinea pedis is small disease, if cannot get timely medical treatment, other body parts can be spread to and cause the tinea manuum, first Tinea, tinea versicolor, jock itch etc., sometimes because itch unbearably and scratch cause local skin to be scratched so that secondary bacterial infection, draws Play serious complication, such as angioleucitis, cellulitis.
According to the difference of symptom, tinea pedis is divided into the three types such as bubble type, erosive type and squama type, currently, treats tinea pedis Method although existing Western medicine paste application, also have Chinese herbal fumigation and washing or bathing etc., go back the treatment of oral administration Traditional chinese medicine medicament, otherwise but treat Imitate not good enough, or inconvenient, or there is certain toxic side effect, therefore patient is often difficult to adhere to treating, so that this disease is anti- Recurrence is made.
The content of the invention
The present invention provides a kind of ointment for treating tinea pedis in view of the deficiencies of the prior art.
The present invention is in order to achieve the above object, using following scheme:A kind of ointment for treating tinea pedis, including following parts by weight Raw material:
5~15 parts of kuh-seng, 6~18 parts of the root bark of shaggy-fruited dittany, 5~18 parts of salicylic acid, 15~30 parts of the tuber of stemona, 3~12 parts of benzoic acid, boron 8~20 parts of acid, 6~18 parts of alumen, 20~60 parts of glycerine.
Present invention also offers the preparation method of above-mentioned ointment:
1) component of each raw-material weight part is taken, kuh-seng, the root bark of shaggy-fruited dittany, the tuber of stemona are first processed into coarse powder, is added water to cook twice, Every time 2 it is small when, collecting decoction, filtration, filtrate is condensed into medicinal extract;
2) salicylic acid, benzoic acid, boric acid, alumen are processed into fine powder with medicinal herb grinder, cross 120 mesh sieves;
3) medicinal extract obtained by step 1) is added in fine powder obtained by step 2), and adds qs glycerin at the same time, stirred with mixer Mix uniformly, to soft or hard appropriateness both can, be stored in shady place with glass or plastic containers.
Application method of the present invention is as follows:Ointment is uniformly applied to affected part, is retained more than six hours.As there is blister in affected part, First blister must then be needled, then smear ointment, to heighten the effect of a treatment.Such as it is used to treat squama type tinea of feet and hands, then is preferably used after coating When preservative film parcel affected part 4 to 6 is small, so that the active ingredient of ointment infiltrates into deep skin, curative effect is improved.
Compared to the prior art the present invention, has the following advantages that and beneficial effect:Cure rate is high, has no adverse reaction, recurs Rate is low, mitigates the symptoms such as itch after smearing at once, mitigates patient suffering.
Embodiment
Embodiment 1:A kind of ointment for treating tinea pedis, includes the raw material of following parts by weight:5 parts of kuh-seng, 6 parts of the root bark of shaggy-fruited dittany, water 5 parts of poplar acid, 15 parts of the tuber of stemona, 3 parts of benzoic acid, 8 parts of boric acid, 6 parts of alumen, 20 parts of glycerine.
Preparation method is as follows:
1) component of each raw-material weight part is taken, kuh-seng, the root bark of shaggy-fruited dittany, the tuber of stemona are first processed into coarse powder, is added water to cook twice, Every time 2 it is small when, collecting decoction, filtration, filtrate is condensed into medicinal extract;
2) salicylic acid, benzoic acid, boric acid, alumen are processed into fine powder with medicinal herb grinder, cross 120 mesh sieves;
3) medicinal extract obtained by step 1) is added in fine powder obtained by step 2), and adds qs glycerin at the same time, stirred with mixer Mix uniformly, to soft or hard appropriateness both can, be stored in shady place with glass or plastic containers.
Embodiment 2:A kind of ointment for treating tinea pedis, includes the raw material of following parts by weight:15 parts of kuh-seng, 18 parts of the root bark of shaggy-fruited dittany, 18 parts of salicylic acid, 30 parts of the tuber of stemona, 12 parts of benzoic acid, 20 parts of boric acid, 18 parts of alumen, 60 parts of glycerine.
Preparation method is the same as embodiment 1.
Embodiment 3:A kind of ointment for treating tinea pedis, includes the raw material of following parts by weight:10 parts of kuh-seng, 12 parts of the root bark of shaggy-fruited dittany, 10 parts of salicylic acid, 20 parts of the tuber of stemona, 8 parts of benzoic acid, 14 parts of boric acid, 12 parts of alumen, 40 parts of glycerine.
Preparation method is the same as embodiment 1.
Application method of the present invention is as follows:Ointment is uniformly applied to affected part, is retained more than six hours.As there is blister in affected part, First blister must then be needled, then smear ointment, to heighten the effect of a treatment.Such as it is used to treat squama type tinea of feet and hands, then is preferably used after coating When preservative film parcel affected part 4 to 6 is small, so that the active ingredient of ointment infiltrates into deep skin, curative effect is improved.
Development to this ointment starts from 2001, is obtained into finally after up to the repetition test of nearly 1 year in inventor Work(.During the last ten years, skin disease such as tinea of feet and hands, ringworm of the body, tinea versicolor, the jock itch etc. of clinical practice caused by fungi is infected in treatment exceed 2000, through statistics, it is as follows to choose model case up to more than 97% for total effective rate:
Case one:Luo, female, 25 years old, hotel waiter, because of the multiple toe space itch of both feet, rotten to the corn flowing water 3 months, in In July, 2003 goes to four hospital dermatology department of Changsha to go to a doctor, doctor check after be diagnosed as " erosive type tinea pedis ", give berberi powder and Tinea is opposed outside ointment and put on the skin, and symptom can be alleviated after medication for a period of time, but is not crossed and recurred how long again, is very worries, after being introduced With this medicinal ointment therapy, smear after a medicine that scratchiness is just obvious to be mitigated, recovery from illness is obtained after continuous use five times.It is advised to pay attention to keeping The cleaning drying of foot, frequently changes footgear, not use others slippers, bath towel etc., with anti-cross infection, be paid a return visit after 1 year, not multiple again Hair.
Case two:Liu, man, 42 years old, civil servant, because double-legged sole and heel peel repeatedly, itch 6 months, in In September, 2006 goes to the refined Annex III hospital dermatology department in Hunan to go to a doctor, and diagnosis are " squama type tinea pedis ", give Da Kening and apply outside, treats Imitate it is undesirable, by friend recommendation use this ointment affected part of exterior coating after again locally parcel preservative film treat, second after medication Its scratchiness mitigates smaller part, and after adhering to medication seven times, symptom disappears and fully recovers.It is advised usually to pay attention to the sanitation and hygiene of foot and do It is dry, to prevent cross-infection in bathhouse, the shoes worn will ventilate well.Paid a return visit after a year and a half, after it replies healing Do not recurred.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, without departing from the technical principles of the invention, some improvement and modification, these improvements and modifications can also be made Also it should be regarded as protection scope of the present invention.

Claims (2)

1. a kind of ointment for treating tinea pedis, it is characterised in that include the raw material of following parts by weight:
5~15 parts of kuh-seng, 6~18 parts of the root bark of shaggy-fruited dittany, 5~18 parts of salicylic acid, 15~30 parts of the tuber of stemona, 3~12 parts of benzoic acid, boric acid 8 ~20 parts, 6~18 parts of alumen, 20~60 parts of glycerine.
2. a kind of preparation method of ointment as claimed in claim 1, it is characterised in that include the following steps:
1) kuh-seng, the root bark of shaggy-fruited dittany, the tuber of stemona are first processed into coarse powder, added water to cook twice, every time 2 it is small when, collecting decoction, filter, will Filtrate is condensed into medicinal extract;
2) salicylic acid, benzoic acid, boric acid, alumen are processed into fine powder with medicinal herb grinder, cross 120 mesh sieves;
3) medicinal extract obtained by step 1) is added in fine powder obtained by step 2), and adds qs glycerin at the same time, stirred with mixer equal It is even, to soft or hard appropriateness both can, be stored in shady place with glass or plastic containers.
CN201711133378.9A 2017-11-16 2017-11-16 A kind of ointment for treating tinea pedis and preparation method thereof Pending CN107929624A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113116977A (en) * 2019-12-31 2021-07-16 郑州维谊生物科技有限公司 Bath powder for treating fungal infection and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102100735A (en) * 2011-01-24 2011-06-22 孙洪恩 Medicinal composition for treating skin diseases
CN103565916A (en) * 2013-11-07 2014-02-12 成都九芝堂金鼎药业有限公司 Traditional Chinese medicine composition for treating keratosis type tinea of feet and hands as well as preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102100735A (en) * 2011-01-24 2011-06-22 孙洪恩 Medicinal composition for treating skin diseases
CN103565916A (en) * 2013-11-07 2014-02-12 成都九芝堂金鼎药业有限公司 Traditional Chinese medicine composition for treating keratosis type tinea of feet and hands as well as preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李骏: "自拟足癣散治疗足癣33例", 《广西中医药》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113116977A (en) * 2019-12-31 2021-07-16 郑州维谊生物科技有限公司 Bath powder for treating fungal infection and preparation method thereof

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Application publication date: 20180420

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