CN1237426A - Chinese patent medicine for external application for curing diseases of scald, burn and dermal ulcer - Google Patents
Chinese patent medicine for external application for curing diseases of scald, burn and dermal ulcer Download PDFInfo
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- CN1237426A CN1237426A CN 98110254 CN98110254A CN1237426A CN 1237426 A CN1237426 A CN 1237426A CN 98110254 CN98110254 CN 98110254 CN 98110254 A CN98110254 A CN 98110254A CN 1237426 A CN1237426 A CN 1237426A
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Abstract
The present invention discloses a Chinese patent drug for external application for curing scald, burn and ulcer of skin, etc.. It uses 60-110 portions of calcined alum, 30-80 portions of rhubarb, 30-80 portions of calcined gypsum, 20-30 portions of bletilla tuber, 1-5 portions of frankincense and 2-8 portions of myrrh as raw material, and adopts conventional preparation process to obtain the invented medicinal powder preparation. It has no toxic side effect, and its effective rate is up to 100%.
Description
The present invention relates to Chinese patent drug technique field, relate in particular to a kind of external Chinese patent medicine that is used for the treatment of diseases such as scald, burn, skin ulcer.
At present use medicine for external use such as JINGWANHONG, moist expose burn ointment usually, treat as oral medicine etc. with transfusion, anti-sanguinin etc. at the medicine that is used for the treatment of scalds, the disease of burning; The treatment medicine that is used for eczema mainly contains antibiotic, Le-Fu-Ye bacteriostatic etc.; Injure wound outward, the ulcer medication mainly is adhesive bandage, yellow amine crystallization, antibiotic etc.; Medication to otitis media, folliculitis, impetigo mainly is an antibiotic, and the medicine for treatment that beriberi is festered has yellow amine crystallization, JIAOXIAN YICIJING etc.; The treatment medicine of pudendal ulcer mainly contains antibiotic, hismanal, ciprofloxacin etc., and the medicine of above various diseases is from the statistical result analysis, and the one drug effect is not remarkable, and treatment time is long; Its two side effect is big, and healing time is long, and patient's tolerance is relatively poor, thereby excavates Chinese medical material repository, seeks that a kind of can to utilize the external Chinese patent medicine of the multiple injury of Chinese herbal treatment be a positive problem.
The objective of the invention is to improve the deficiency of prior art, and a kind of low price is provided, easy to use, the external Chinese patent medicine that is used for the treatment of multiple diseases such as scald, burn, skin ulcer that therapeutic effect is good.
The objective of the invention is to be achieved by following technical solution: a kind of external Chinese patent medicine that is used for the treatment of diseases such as scald, burn, skin ulcer, it contains (by weight) dried Alumen 60-110 part, Radix Et Rhizoma Rhei 30-80 part, Gypsum Fibrosum Preparatum 30-80 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-30 part, Olibanum 1-5 part, Myrrha 2-8 part.
External Chinese patent medicine of the present invention embodiment preferably is: a kind of external Chinese patent medicine that is used for the treatment of diseases such as scald, burn, skin ulcer, and it contains (by weight) dried Alumen 75-95 part, Radix Et Rhizoma Rhei 45-65 part, Gypsum Fibrosum Preparatum 45-65 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 23-27 part, Olibanum 2-4 part, Myrrha 4-6 part.
The embodiment of external Chinese patent medicine the best of the present invention is, a kind of Chinese patent medicine that is used for the treatment of diseases such as scald, burn, skin ulcer, and it contains 80 parts of (by weight) dried Alumens, 50 parts of Radix Et Rhizoma Rhei, 50 parts of Gypsum Fibrosum Preparatum, from 25 parts of splendid achnatherums, 3 parts of Olibanums, 5 parts of Myrrhas.
External Chinese patent medicine of the present invention is to make powder according to the conventional technology of preparing of Chinese medicine,
The principles of formulating prescriptions of external Chinese patent medicine of the present invention are, reducing swelling and alleviating pain, and sterilizing and itch-relieving, removing the necrotic tissue and promoting granulation, blood circulation promoting and blood stasis dispelling pulls out dried removing dampness, arresting hemostasia and suppuration, the no cicatrix in back more, the effect of Chinese medicinal ingredients of the present invention is:
Dried Alumen puckery cold in nature for the white opacity crystalline solid, has detoxifcation, doctor's skin ulcer, and removing dampness is antipruritic, holds back to rush down hemostasis, the switching of eliminating the phlegm, the effect of heat clearing away jaundice eliminating is mainly used in the treatment scabies, diseases such as eczema.
Radix Et Rhizoma Rhei bitter in the mouth cold in nature has stasis removing, and the effect that eliminating fire and detoxication, clots absorbing stimulate the menstrual flow cures mainly the excess-heat constipation, the stomachache distension, and dysentery, jaundice, the blood stasis amenorrhea, the conjunctival congestion aphtha, diseases such as carbuncle, external application can be controlled scald.
Gypsum Fibrosum Preparatum acrid-sweet flavor in Great Cold cures mainly the hyperpyrexia excessive thirst, and lung-heat is breathed with cough and disease such as toothache due to stomach-fire, but the promoting tissue regeneration and ulcer healing that is for external application.
Pseudobulbus Bletillae (Rhizoma Bletillae) cold nature bitter in the mouth has tonifying the lung, and the hemostatic effect cures mainly the deficiency of the lung and owes to cough, and spits blood diseases such as ulcer haemorrhage.
The little bitter in the mouth suffering of Olibanum cures mainly breast abdomen pain, dysmenorrhea, traumatic injury, diseases such as carbuncle.
Do not have the flat bitter in the mouth of the property of medicine, have promoting blood circulation to remove blood stasis, effects such as reducing swelling and alleviating pain cure mainly carbuncle and swell and ache, diseases such as traumatic injury.
Medicament composing prescription science of the present invention, all composition comes from the 5th edition Chinese medicine that records of China's " pharmacopeia ", does not have toxic and side effects, its described various kinds of drug has been brought into play reducing swelling and alleviating pain, sterilizing and itch-relieving, removing the necrotic tissue and promoting granulation, blood circulation promoting and blood stasis dispelling pulls out dried removing dampness, arresting hemostasia and suppuration, more the effect of no cicatrix after, to burn, scald otitis media, eczema ulcer, beriberi is festered, various carbuncle sore, folliculitis, cloudy place bromhidrosis, impetigo, oral ulcer, pudendal ulcer, trauma ulcer, diseases such as skin grafting dermepenthesis operation all have the positive therapeutic effect.
The test example
1, the skin acute toxicity test of external Chinese patent medicine of the present invention
(1) test objective: observe the toxic reaction that animal subject produces because of Absorption intact skin and damaged skin short term contact.
(2) animal is selected: 8 of the white rabbit (divide two dosage groups, 4 every group, male and female half and half) of selecting 2-2.5kg.
(3) test is prepared: white rabbit is exposed the exocuticle of white rabbit being tried preceding 24 hours with its both sides, back shearing machine unhairing, and the unhairing scope is each 7.5cm * 10cm of both sides, adds up to 150cm
2, the skin at unhairing position must not be injured because of unhairing, otherwise should not make the toxicity test of complete skin.
(4) test method: with (4 every group of two dosage groups of 8 branches of the rabbit after the unhairing, each two of male and female), carried out disinfection to trying skin (every is tried the contrast test that rabbit carries out intact skin and damaged skin simultaneously) respectively, (small dose group is drawn 2 groined types to scratch epidermis with the sterile surgical cutter as groined type, heavy dose of group is drawn 8 groined types), slight oozing of blood degree of being appears with skin.Directly spread to apply with Chinese medicine powder of the present invention and scratch the place, with gauze and immobilization with adhesive tape, with the rabbit sub-cage rearing after the wrapping at epidermis.
(5) observe and the result: give to be subjected to behind the reagent thing 24 hours, find no and be poisoned to death, binder is removed, and with warm water remove remain on the skin be subjected to the reagent thing time find that all the oozing of blood positions are all dry and hard, continue to observe seven days, 8 of two dosage groups are tried none death of rabbit, and big of dry and hard epidermis all comes off, and the epidermis after coming off does not have cicatrix, in the observation period, tried the outward appearance of rabbit, the mental status, appetite, stool, the colour of skin is breathed no any unusual.
Above-mentioned evidence: external Chinese patent medicine of the present invention is nontoxic, safety, and hemostasis and pain-relieving pulls out dried removing dampness at short notice, more the therapeutic effect of the no cicatrix in back.
2, the skin anaphylactic test of external Chinese patent medicine of the present invention
(1) test objective: the purpose of this test is to observe animal skin, and after repeating contact and being subjected to the reagent thing, medicine is at the intravital sensitivity response of flesh.
(2) animal is selected: the albino guinea-pig (respectively 15 of male and female) that to select 30 body weight be 250-300g.
(3) test is prepared: being tried preceding 24 hours, 3 * 3cm is respectively removed in the guinea pig back both sides
2Hair, expose white exocuticle, the skin at unhairing position must not be injured because of unhairing, otherwise be not useable for the test.
(4) test method
1. test grouping, by body weight, sex is divided into three groups at random with Cavia porcellus, and 10 every group, male and female half and half.First group is tried medicine of the present invention; Second group of negative control gives excipient (lanoline); The 3rd group of positive control, give 1% 2,4-dinitro-chloro-benzene (DNCB).
2. sensitization contact: get and be subjected to reagent thing 0.2g, be mixed with an amount of lanoline excipient, be coated in and tried depilation district, back, Cavia porcellus left side, fix every animal sub-cage rearing, lasting 6 hours with gauze and adhesive plaster.The 7th day and the 14th day, in kind repeat once.The negative control group Cavia porcellus is coated with lanoline; Positive thing matched group is coated with 1%DNCB, and method is with being subjected to reagent thing group.
3. excite contact: in last give be subjected to reagent thing sensitization after 14 days, will be subjected to reagent thing 0.2g to be applied to depilation district, guinea pig back right side, remove after 6 hours and be subjected to the reagent thing, observe the skin allergy situation at once, then in 24,48, observed once more in 72 hours.Negative and positive controls operation and observational technique is same is subjected to reagent thing group is the lanoline excipient but negative control group is coated with, and positive controls is coated with is 1% DNCB.
(5) observe and the result: through to 6 hours the observation of sensitization that is subjected to reagent thing group Cavia porcellus and the 7th day, repeated sensitization test (STT) on the 14th day to observe, sensitization contact negative and positive controls is observed and is all found no the erythema generation; After this to exciting the observation of contact test, also find no the generation of erythema phenomenon.By above evidence, external used medicine of the present invention is more normal to dermoreaction, no sensitization reaction.
3, the clinical trial of external Chinese patent medicine of the present invention:
External Chinese patent medicine of the present invention has carried out clinical practice half a year in three hospitals above county level, treats 564 exceptions altogether and hinders disease patient, wherein wound 128 examples, 58 examples of burning, scald 65 examples, eczema ulcer 86 examples, oral ulcer 46 examples, beriberi ulcer 64 examples, otitis media 38 examples, pudendal ulcer 89 examples, cure rate reaches 95%, the treatment effective percentage reaches 100%, and its typical case history is now taken passages as follows:
1, Lee * *, the man, 70 years old, suffer from pudendal ulcer for many years, once went to a doctor in the related hospitals treatment, recovery from illness is always applied the i.e. recovery from illness after twice 7 days of this medicine through spreading.
2, Liu * *, the woman 11 years old, because of suffering from trauma ulcer, spreads and applies this medicine and fully recover after one time 2 days.
3, Sui * *, the man 35 years old, because of flame burn, spreads and applies this medicine secondary, i.e. recovery from illness after seven days.
4, Zhu * *, the woman, 10 years old, suffer from carbuncle skin ulcer diameter 5cm, pain unbearably, this medicine of application after half an hour pain disappear, apply a deuterzooid medicine after three days in addition, i.e. recovery from illness after seven days.
5, Zhu * *, the man, 25 years old, suffered from cloudy place bromhidrosis several years, through this medicated powder of external application secondary, recovery from illness after 3 days.
6, Song * *, the woman, 62 years old, because of the scald left arm of opening fire, the part is ulcer, this medicine of external application 2 times promptly reached recovery from illness in 10 days.
The specific embodiment of medicine of the present invention is as follows:
Embodiment 1
Take by weighing dried Alumen 60g, Radix Et Rhizoma Rhei 30g, Gypsum Fibrosum Preparatum 30g, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Olibanum 1g, Myrrha 2g, with above-mentioned Chinese crude drug routinely the Chinese medicine preparation technology make powder and be described external Chinese patent medicine of the present invention.
Embodiment 2
Take by weighing dried Alumen 110g, Radix Et Rhizoma Rhei 80g, Gypsum Fibrosum Preparatum 80g, Pseudobulbus Bletillae (Rhizoma Bletillae) 30g, Olibanum 5g, Myrrha 8g, with above-mentioned Chinese crude drug routinely the Chinese medicine preparation technology make powder, be described external Chinese patent medicine of the present invention.
Embodiment 3
Take by weighing dried Alumen 75g, Radix Et Rhizoma Rhei 45g, Gypsum Fibrosum Preparatum 45g, Pseudobulbus Bletillae (Rhizoma Bletillae) 23g, Olibanum 2g, Myrrha 4g, with above-mentioned Chinese crude drug routinely the Chinese medicine preparation technology make powder, can obtain external Chinese patent medicine of the present invention.
Embodiment 5
Take by weighing dried Alumen 80g, Radix Et Rhizoma Rhei 50g, Gypsum Fibrosum Preparatum 50g, Pseudobulbus Bletillae (Rhizoma Bletillae) 25g, Olibanum 3g, Myrrha 5g, with above-mentioned Chinese crude drug routinely the Chinese medicine preparation technology make powder, can obtain external Chinese patent medicine of the present invention.
Claims (4)
1, a kind of external Chinese patent medicine that is used for the treatment of diseases such as scald, burn, skin ulcer, it contains (by weight) dried Alumen 60-110 part, Radix Et Rhizoma Rhei 30-80 part, Gypsum Fibrosum Preparatum 30-80 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-30 part, Olibanum 1-5 part, Myrrha 2-8 part.
2, the external Chinese patent medicine of diseases such as treatment scald according to claim 1, burn, skin ulcer, it contains (by weight) dried Alumen 75-95 part, Radix Et Rhizoma Rhei 45-65 part, Gypsum Fibrosum Preparatum 45-65 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 23-27 part, Olibanum 2-4 part, Myrrha 4-6 part.
3, the external Chinese patent medicine of diseases such as treatment scald according to claim 1, burn, skin ulcer, it contains 80 parts of (by weight) dried Alumens, 50 parts of Radix Et Rhizoma Rhei, 50 parts of Gypsum Fibrosum Preparatum, 25 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 3 parts of Olibanums, 5 parts of Myrrhas,
4,, it is characterized in that described external Chinese patent medicine makes powder according to the conventional technology of preparing of Chinese medicine according to the external Chinese patent medicine of diseases such as the described treatment scald of arbitrary claim in the claim 1 to 3, burn, skin ulcer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98110254A CN1068785C (en) | 1998-05-29 | 1998-05-29 | Chinese patent medicine for external application for curing diseases of scald, burn and dermal ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98110254A CN1068785C (en) | 1998-05-29 | 1998-05-29 | Chinese patent medicine for external application for curing diseases of scald, burn and dermal ulcer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1237426A true CN1237426A (en) | 1999-12-08 |
| CN1068785C CN1068785C (en) | 2001-07-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98110254A Expired - Fee Related CN1068785C (en) | 1998-05-29 | 1998-05-29 | Chinese patent medicine for external application for curing diseases of scald, burn and dermal ulcer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1068785C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101041014B (en) * | 2007-04-21 | 2010-07-28 | 孟祥宝 | Plaster for treating scald and burn for external application |
| CN103191205A (en) * | 2013-04-22 | 2013-07-10 | 吉林农业大学 | Externally-used medicine for treating grease-heel of equus animals and preparation method thereof |
| WO2019080115A1 (en) * | 2017-10-27 | 2019-05-02 | 江苏奇力康皮肤药业有限公司 | Long-acting sustained-release traditional chinese medicine cold compress for treating skin ulcer |
| CN109908270A (en) * | 2019-04-30 | 2019-06-21 | 张华利 | A kind of medicament for treating scald |
| CN110876779A (en) * | 2019-12-23 | 2020-03-13 | 山东中医药大学 | Traditional Chinese medicine composition for treating oral ulcer and preparation method and application thereof |
-
1998
- 1998-05-29 CN CN98110254A patent/CN1068785C/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101041014B (en) * | 2007-04-21 | 2010-07-28 | 孟祥宝 | Plaster for treating scald and burn for external application |
| CN103191205A (en) * | 2013-04-22 | 2013-07-10 | 吉林农业大学 | Externally-used medicine for treating grease-heel of equus animals and preparation method thereof |
| CN103191205B (en) * | 2013-04-22 | 2014-06-25 | 吉林农业大学 | Externally-used medicine for treating grease-heel of equus animals and preparation method thereof |
| WO2019080115A1 (en) * | 2017-10-27 | 2019-05-02 | 江苏奇力康皮肤药业有限公司 | Long-acting sustained-release traditional chinese medicine cold compress for treating skin ulcer |
| CN109908270A (en) * | 2019-04-30 | 2019-06-21 | 张华利 | A kind of medicament for treating scald |
| CN110876779A (en) * | 2019-12-23 | 2020-03-13 | 山东中医药大学 | Traditional Chinese medicine composition for treating oral ulcer and preparation method and application thereof |
| CN110876779B (en) * | 2019-12-23 | 2021-11-09 | 山东中医药大学 | Traditional Chinese medicine composition for treating oral ulcer and preparation method and application thereof |
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| Publication number | Publication date |
|---|---|
| CN1068785C (en) | 2001-07-25 |
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