CN1172700C - External applied medicine for curing burn and preparing method thereof - Google Patents
External applied medicine for curing burn and preparing method thereof Download PDFInfo
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- CN1172700C CN1172700C CNB021103275A CN02110327A CN1172700C CN 1172700 C CN1172700 C CN 1172700C CN B021103275 A CNB021103275 A CN B021103275A CN 02110327 A CN02110327 A CN 02110327A CN 1172700 C CN1172700 C CN 1172700C
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Abstract
The present invention relates to an external drug for treating burns, which uses frankincense, myrrh, golden thread and charred sanguisorba root, etc. as raw materials. The raw materials are put in sesame oil to be decocted into an oil preparation for use. When used for treating burns, the drug has the characteristics of short course of treatment, rapid recovery and rapid pain elimination, and the total effective rate of the drug for treating burns reaches 98%.
Description
One, technical field
The present invention relates to a kind of medicine for the treatment of burn, particularly a kind of is the external used medicine of feedstock production with the Chinese herbal medicine.The invention still further relates to the preparation method of this medicine.
Two, background technology
Burn is commonly encountered diseases, the frequently-occurring disease of surgical clinical, is found in any age bracket.Recent research shows that the sickness rate of child below 5 years old is 24.02%, occupies first of each age group sickness rate; 21～30 years old young sickness rate is 22.82%, occupies second.After this with age growth, its sickness rate reduces gradually.
Modern western medical science surgery burn medical model is the dry type therapy, and the tannin with 5%, 10% silver nitrate, silver sulfadiazine suspension are coated with outward or cooperate that lamp is roasting, hot hair dryer dries up etc. open wound surface is carried out tanning, cautery or carries out tendency towards compromise and excise skin grafting etc.This technology has obtained carrying out well clinically.And deep burn cut (cutting) crust allosome (xenogenesis) skin+also obtained certain progress from the development of body microparticle skin or stamp skin mixed transplantation art and artificial skin.Since the nineties in last century, the experiment of various somatomedin wound repairinies and clinical observation have also obtained stem-winding result.
In recent years the most noticeable progress is the MEBT by the auspicious proposition of Chinese scholar Xu Rong (MEBT)/MEBO (moist expose burn ointment) therapy in 1986.The core theory of this therapy will promote regeneration to implement treatment all the time exactly, the higher level that on behalf of present burn wound, this technology repair, we have reason to believe, along with constantly improving and the appearance of the similar drug of the different prescriptions of same principle of this technology, be bound to walk out a brand-new burn treating road.But applicable cases just at present, moist expose burn ointment still have the relative course of treatment long, recovery from illness is slower, and a fly in the ointment such as the medical care technical difficulty is bigger.
The Chinese medicine burn preparation of some subcrustal healing methods such as Cortex Ziziphi spinosae Radicis tincture, Radix Sanguisorbae Cortex Phellodendri tincture, curative effect is also better, but patient's sharp ache after use.
Three, technology contents
The purpose of this invention is to provide rapid, the treatment external use burn treating medicine thing fast, good analgesic effect of fully recovering of a kind of curative effect.
The preparation method of this medicine is provided, and is another goal of the invention of the present invention.
External used medicine of the present invention is made by the following weight proportion raw material:
Olibanum 80～120 Myrrhas 80～120
Rhizoma Coptidis 30～40 charred Radix Sanguisorbae 30～40
Calculus Bovis 20～25 Corium elephatiss 20～30
Margarita 15～25 Borneolum Syntheticums 2～4
Oleum sesami 200～350
The present invention adopts above-mentioned raw materials, and making dosage form is the treatment external use burn treating medicine thing of oil preparation.
The preparation method of oil preparation of the present invention is: the fine powder that Olibanum, Myrrha, Rhizoma Coptidis, charred Radix Sanguisorbae, Calculus Bovis, Corium elephatis, Margarita pulverize separately is become 80～120 purposes; join in 200～250 ℃ the hot Oleum sesami; decoct 40～60 minutes, the elimination medicinal residues add the Borneolum Syntheticum mixing at last and make.
Among the present invention, the medicine addition sequence that decocts in the process has certain influence for the curative effect of medicine, usually, add earlier Corium elephatis, decoct 20～30 minutes after, add all the other medicines except that Borneolum Syntheticum again, continue to decoct 20～30 minutes, the oil preparation of making has better therapeutic.
In medicament composing prescription of the present invention, Olibanum can circulation of qi promoting in blood, and pain relieving power is strong, Myrrha is gone into blood system partially, be longer than dissipating blood stasis, the broken power of letting out is big, and the two share, be monarch drug altogether, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain, and because of it can be invigorated blood circulation, circulation of qi promoting, putrefaction removing have the merit that granulation promoting is put on flesh concurrently, the pain that the burn initial stage is used can be ended, and the ulcer that the later stage is used can heal; The charred Radix Sanguisorbae cooling blood for hemostasis, heat-clearing and toxic substances removing is held back skin ulcer, zoopery confirms that the external of Radix Sanguisorbae preparata powder has therapeutical effect to experimental scald, it share mutually with divide the Rhizoma Coptidis of excess-heat, Calculus Bovis based on clearing heat in QI system, and purpose is to remove the paathogenic factor of fire-toxin for suffering from, and therefore is all ministerial drug; Margarita, Corium elephatis, Borneolum Syntheticum then are the common drug compatible combination of external curing trauma ulcer disunion of a specified duration, wherein Margarita is longer than removing toxic substances and promoting granulation, Corium elephatis arresting bleeding and healing up ulcer, kind especially granulation promoting skin, Borneolum Syntheticum external clearing heat for detumescence, antipruritic pain relieving, this three flavor is that assistant makes it medicine in the side.All medicine compatibilities in the side gather the merit of pain, promoting tissue regeneration and ulcer healing in blood circulation promoting competent silt, the detoxifcation altogether.
The present invention is pure Chinese medicine external used medicine, and its advantage is that the absorption of skin ulcer face is fast, and pain relieving is rapid, does not have and infects, and does not make skin graft, and cure time is short, and is evident in efficacy, easy to use, has no side effect, and do not stay pathologic scar after healing.
Can be used for chemical drugs damages such as all kinds of soup fire burns, oil scald, metal object burn and scald, electric burn, gunpowder burning and injured and strong acid, highly basic etc.In addition, clinically be used for that impetigo, folliculitis, sycosis vulgaris, hidradenitis suppurativa, cellulitis, decubital ulcer, ulcus cruris and chilblain etc. are suppurative, the ulcer skin infection all has satisfactory effect.For the suppurative ulcer that burns rear wound infection suppurates or other reason cause, external all can alleviate the state of an illness, shortens the course of treatment, accelerates recovery from illness.
For showing the effect of Drug therapy burn of the present invention,, prove to have curative effect really through the clinical observation of 50 routine systems.In the 50 routine cases, male 40 examples, women 10 examples, the oldest 65 years old, minimum 9 months.Burn cause is that water oil is scalded 24 examples, metal burn and scald 10 examples, and diesel oil, petrol burn 6 examples, electric burn 2 examples, chemical burn 3 examples, lime water is scalded 2 examples, other 3 examples of burning.According to the position statistics of burn, shank 27 places, foot 20 places, hand 16 places, arm 9 places, facial 11 places of head and neck, trunk 8 places.Modified rule of Nine and degree of depth standard technique according to the 4th edition " surgery " teaching material in People's Health Publisher are carried out the classification of the burn surface area and the degree of depth, with the burn degree be divided into gently, in, severe 3 classes.Wherein in the 50 routine cases, slight burn and scald 28 examples, moderate burn and scald 21 examples, severe burn 1 example.
Above-mentioned 50 routine cases all use external used medicine of the present invention to treat, and using method is with after burn wound's cleaning, with oil preparation external application wound surface.Slight external application once, moderate medication 7 days, the next day drug of topical application 1 time, severe medication 20 days, the next day drug of topical application 1 time.
Curative effect judging standard is: recovery from illness: wound surface heals fully, and slight 5 days, moderate 7 days, severe 20 days.Effectively: it is effective surpassing cure time healing person.Invalid: burn wound does not have and dwindles in the above stipulated time, not healing person.
By above-mentioned curative effect judging standard 50 example treatment cases are carried out curative effect judgement and statistics statistics, cure rate is 80%, and its 95% confidence interval is 66～90%, and total effective rate is 98%, its 95% confidence interval 89～100%, and concrete outcome sees Table 1.
Table 1 50 examples a burn case and treat curative effect statistical result
| The burn degree | Case load | Recovery from illness | Effectively | Invalid |
| Slightly | 28 | 24 | 4 | |
| Moderate | 21 | 16 | 4 | 1 |
| Severe | 1 | 1 | ||
| Add up to | 50 | 40 | 9 | 1 |
Four, the specific embodiment
Take by weighing raw material (kilogram) according to following weight.
Olibanum 1.2 Myrrhas 1.1
Rhizoma Coptidis 0.3 charred Radix Sanguisorbae 0.4
Calculus Bovis 0.2 Corium elephatis 0.3
Margarita 0.2 Borneolum Syntheticum 0.025
Oleum sesami 25
Preparation method:
At first, with Olibanum, Myrrha, Rhizoma Coptidis, charred Radix Sanguisorbae, Calculus Bovis, Corium elephatis, Margarita pulverize separately, and by standby behind 100 mesh sieves.Oleum sesami is heated to 250 ℃, adds Corium elephatis, decocts 20 minutes, and temperature is reduced to 200 ℃, add all the other each medicines except that Borneolum Syntheticum again, continue to decoct 30 minutes, stop heating, filter, remove medicinal residues, Borneolum Syntheticum is added mixing in the oil that is used as medicine, divide in the 10ml vial of packing into Jiao Gai lid rate, make the present invention and treat burn and use oil preparation, be put in the preservation of shady and cool place.
Claims (6)
1, a kind of external used medicine for the treatment of burn is characterized in that it is the external used medicine of being made by following materials based on weight:
Olibanum 80～120 Myrrhas 80～120
Rhizoma Coptidis 30～40 charred Radix Sanguisorbae 30～40
Calculus Bovis 20～25 Corium elephatiss 20～30
Margarita 15～25 Borneolum Syntheticums 2～4
Oleum sesami 200～350.
2, treatment external use burn treating medicine thing according to claim 1 is characterized in that this medicine is made oil preparation.
3, the preparation method of the described treatment external use burn treating medicine of claim 2 thing; it is characterized in that Olibanum, Myrrha, Rhizoma Coptidis, charred Radix Sanguisorbae, Calculus Bovis, Corium elephatis, Margarita pulverize separately are become 80～120 order fine powders; join in the hot Oleum sesami and decoct 40～60 minutes; behind the elimination medicinal residues, add the Borneolum Syntheticum mixing and make.
4, the preparation method of treatment external use burn treating medicine thing according to claim 3, it is characterized in that Oleum sesami is heated to 200～250 ℃ after, add medicine again and decoct.
5, according to the preparation method of claim 3 or 4 described treatment external use burn treating medicine things, it is characterized in that the order that medicine adds is to add Corium elephatis earlier, add the other medicines except that Borneolum Syntheticum again.
6, the preparation method of treatment external use burn treating medicine thing according to claim 5, after it is characterized in that adding Corium elephatis and decocting 20～30 minutes, the other medicines that add again except that Borneolum Syntheticum decoct 20～30 minutes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021103275A CN1172700C (en) | 2002-05-09 | 2002-05-09 | External applied medicine for curing burn and preparing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021103275A CN1172700C (en) | 2002-05-09 | 2002-05-09 | External applied medicine for curing burn and preparing method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1456178A CN1456178A (en) | 2003-11-19 |
| CN1172700C true CN1172700C (en) | 2004-10-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021103275A Expired - Fee Related CN1172700C (en) | 2002-05-09 | 2002-05-09 | External applied medicine for curing burn and preparing method thereof |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102283887B (en) * | 2011-09-07 | 2013-09-25 | 王全英 | Ointment for treating burn |
| CN102552480A (en) * | 2012-02-21 | 2012-07-11 | 白亚军 | Ointment for treating burn and scald and preparation method thereof |
| CN104645048A (en) * | 2015-03-11 | 2015-05-27 | 黄萍 | Traditional Chinese medicine composition for treating sthenic fever type hidradenitis suppurativa |
| CN106266407A (en) * | 2016-10-12 | 2017-01-04 | 徐琳 | A kind of external used medicine treating burn |
| CN106389714A (en) * | 2016-10-24 | 2017-02-15 | 周代君 | Burn-treated plaster |
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2002
- 2002-05-09 CN CNB021103275A patent/CN1172700C/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN1456178A (en) | 2003-11-19 |
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