CN106822846A - It is a kind of to treat herbal composite of tinea pedis and preparation method thereof - Google Patents
It is a kind of to treat herbal composite of tinea pedis and preparation method thereof Download PDFInfo
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- CN106822846A CN106822846A CN201710170741.8A CN201710170741A CN106822846A CN 106822846 A CN106822846 A CN 106822846A CN 201710170741 A CN201710170741 A CN 201710170741A CN 106822846 A CN106822846 A CN 106822846A
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- tinea pedis
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- ching
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- 201000004647 tinea pedis Diseases 0.000 title claims abstract description 42
- 239000002131 composite material Substances 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims description 14
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- 235000008397 ginger Nutrition 0.000 claims abstract description 31
- 244000089698 Zanthoxylum simulans Species 0.000 claims abstract description 30
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 28
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 28
- 229910021538 borax Inorganic materials 0.000 claims abstract description 28
- 229940116229 borneol Drugs 0.000 claims abstract description 28
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 28
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K33/22—Boron compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/906—Zingiberaceae (Ginger family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Public Health (AREA)
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- Medical Informatics (AREA)
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- General Chemical & Material Sciences (AREA)
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Abstract
The invention discloses a kind of herbal composite for treating tinea pedis, including following weight portion raw material:8~20 parts of Chinese prickly ash, 12~16 parts of ginger, 10~20 parts of frutus cnidii, 18~30 parts of ching-chieh, windproof 10~15 parts, 12~30 parts of notopterygium root, 10~15 parts of corter pseudolaricis, 8~15 parts of azedarach, 0.3~0.8 part of Tween 80,1~3 part of alumen, 0.5~1 part of borax, 0.8~2 part of borneol.The present invention has good antalgesic-antipruritic, anti-inflammatory suppuration, the effect of restraining and sterilizing bacteria, by scientific matching, using extracting technique of Chinese medicine, fully extract to the medicative drug ingedient of tinea pedis, to treating with the serious tinea pedis symptom effect is significant such as foot odour, pin sufferings, foot's erosionization water, cure rate is up to 95.3%, Traditional Chinese medicinal spray prepared by the present invention is easy to use, and lasting medicine is nontoxic non-stimulated, any damage will not be caused to human body, is worthy to be popularized.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine, more particularly to a kind of herbal composite and its system for treating tinea pedis
Preparation Method.
Background technology
Tinea pedis, scientific name tinea pedis is the foot dermatosis caused by pathogenic fungus, with infectiousness.Clinical manifestation is pin
Blister, decortication or skin whitening are played between toe wet soft, also may occur in which rotten to the corn or pachyderma, coarse, cracking, and vola pedis can be spread to
And edge, itching.With local suppuration, redness, pain, inguinal lymphadenopathy, or even shank erysipelas and honeycomb group can be formed
Knit the scabies secondary infections such as inflammation.Due to being held by hand place of itching, often infect and the tinea manuum (fungal infection of the hand) occurs to hand.Fungi is raw on (toe) first is referred to
It is long, then into onychomycosis (onychomycosis).During tinea pedis is mainly in, young people, children are rare, and male is typically greater than women, due to pathogen
Difference, the sanitary condition of patient and the difference of constitution, its clinical manifestation is also different.Medically generally by three types of tinea pedis point:It is rotten
Rotten type, vesicle, scales of skin that peel off keratinization type tinea pedis.1. erosive type:It is apt to occur between the 3rd and the 4th, the 4th and the 5th toe.From the beginning of between toe
Humidity, dipping turns white, and after the furfur that dries up, it is moistening, the rotten to the corn face of flush or with breach to peel off scurf, has and very itches, easy to be secondary
Infection.2nd, vesicle:It is apt to occur in foot edge, foot bottom.From the beginning of being the full phlysis of wall thickness, the be fused into bleb having, blister liquid
It is transparent, around without blush.Feel and very itch, often erysipelas, angioleucitis etc. are caused because of scabies secondary infection after scratching.3rd, scales of skin that peel off angling
Type:It is apt to occur in heel, foot edge portion.The people of 70-80% has tinea pedis in adult, and simply weight is different.Often aggravated in summer, the winter
Season mitigates, and also someone is not healed throughout the year.Expert represents, nearly eighty per cant patient tinea pedis frequent recurrence, and topmost reason is exactly not advise
Model medication, including correct drug therapy tinea pedis is not used, or pedicure journey does not use medicine to specifications, so as to cause to make
Arch-criminal fungi into tinea pedis is not removed thoroughly, is run into and regrow after suitable environment breeding so that tinea pedis symptom is sent out repeatedly
Make.The medicine of existing treatment tinea pedis mainly has Western medicine spray, Traditional Chinese medicine foot bath powder and Chinese medicinal ointment.Wherein, Western medicine spray stimulates
Property it is big, it is evident in efficacy, but cure the symptoms, not the disease, be discontinued easily repeatedly;And though Traditional Chinese medicine foot bath powder and Chinese medicinal ointment are effective, can only use
In foot, it is impossible to prevent the cross-infection of foot and footgear and towel, so equally existing, treatment is not thorough, the course for the treatment of is long, easily anti-
Multiple problem.Based on above statement, the present invention is proposed and a kind of treats herbal composite of tinea pedis and preparation method thereof.
The content of the invention
The invention aims to solve shortcoming present in prior art, and a kind of medium-height grass for treating tinea pedis for proposing
Drug composition and preparation method thereof.
A kind of herbal composite for treating tinea pedis, including following weight portion raw material:8~20 parts of Chinese prickly ash, ginger 12~
16 parts, 10~20 parts of frutus cnidii, 18~30 parts of ching-chieh, windproof 10~15 parts, 12~30 parts of notopterygium root, 10~15 parts of corter pseudolaricis,
8~15 parts of azedarach, 0.3~0.8 part of Tween 80,1~3 part of alumen, 0.5~1 part of borax, 0.8~2 part of borneol.
Preferably, a kind of raw material of described herbal composite for treating tinea pedis, including following weight portion:Chinese prickly ash 10~
18 parts, 13~15 parts of ginger, 12~18 parts of frutus cnidii, 19.8~28 parts of ching-chieh, windproof 11~14 parts, notopterygium root 13.2~28
Part, 11~14 parts of corter pseudolaricis, 10~14 parts of azedarach, 0.4~0.7 part of Tween 80,1.2~2.4 parts of alumen, borax 0.6~0.8
Part, 0.96~1.6 part of borneol.
Preferably, a kind of raw material of described herbal composite for treating tinea pedis, including following weight portion:Chinese prickly ash 15
Part, 14 parts of ginger, 15 parts of frutus cnidii, 24 parts of ching-chieh, windproof 12 parts, 22 parts of notopterygium root, 12 parts of corter pseudolaricis, 12 parts of azedarach, tell
800.5 parts of temperature, 2 parts of alumen, 0.7 part of borax, 1.2 parts of borneol.
Preferably, the ching-chieh, windproof, notopterygium root mass ratio are 1.8~2:1:1.2~2.
Preferably, the alumen, borax, the mass ratio of borneol are 2~3:1:1.6~2.
Preferably, the herbal composite is Traditional Chinese medicinal spray.
The invention allows for a kind of preparation method of the herbal composite for treating tinea pedis, comprise the following steps:
S1, the Chinese prickly ash of preferably described proportion, ginger, frutus cnidii, ching-chieh, windproof, notopterygium root, corter pseudolaricis, azedarach, tween
80th, borax, alumen and borneol are standby;
S2, the Chinese prickly ash by step S1, ginger, frutus cnidii are added in No. 1 Chinese medicine extracting tank, after soaking 1~2h,
High temperature decocts 8~12h, obtains volatile oil A and extract solution B;
S3, the ching-chieh in step S1, windproof, notopterygium root, corter pseudolaricis, azedarach are added in No. 2 Chinese medicine extracting tanks, plus
After water soaks 1~2h, high temperature decocts 8~12h, obtains extract solution C;
S4, the extract solution C merging by gained in the extract solution B and step S3 of gained in step S2, add 2.8~3.2 times
Ethanol, after being stirred with the rotating speed of 260~320r/min, stand 20~30h, filter to take supernatant D;
S5, the borax by step S1, alumen and borneol are dissolved in the supernatant D of gained in step S4, add step S2
The volatile oil A and Tween 80 of gained, are fully ground 2~4 times, and 5~8min is ground every time, and after grinding is uniform, quantitative separating is obtained final product.
Preferably, in the step S2 add water for Chinese prickly ash, ginger, 7.5~10.5 times of frutus cnidii total amount;In step S3
Amount of water for ching-chieh, windproof, notopterygium root, corter pseudolaricis, 7.5~10.5 times of azedarach total amount.
Preferably, the ethanol in the step S4 is medical ethanol that concentration is 75%.
A kind of herbal composite for treating tinea pedis proposed by the present invention, its have good antalgesic-antipruritic, anti-inflammatory suppurate,
The effect of restraining and sterilizing bacteria, by scientific matching, using extracting technique of Chinese medicine, fully extract to the medicative medicine of tinea pedis into
Point, to treating with the serious tinea pedis symptom effect is significant such as foot odour, pin sufferings, foot's erosionization water, cure rate is up to 95.3%,
Traditional Chinese medicinal spray prepared by the present invention is easy to use, and lasting medicine is nontoxic non-stimulated, and any damage will not be caused to human body, is worth
Promote.
The below function for raw materials of traditional Chinese medicinal materials of the present invention and effect:
Chinese prickly ash:Warming spleen and stomach for dispelling cold, dehumidifying, analgesic, desinsection, solution fish raw meat poison;Control having indigestion stop drink, trusted subordinate's crymodynia, vomiting, oh,
Cough with dyspnea, wind-cold-dampness arthralgia, diarrhea, dysentery, colic, dentalgia, roundworm disease, enterobiasis, pruritus vulvae, sore scabies;Chinese prickly ash water extract and ether
Extract has good analgesic activity, and its volatile oil has certain suppression and killing to 11 kinds of dermatophytes and 4 kinds of deep fungals
Effect;
Ginger:Inducing sweat and dispelling exogenous evils, warming middle energizer to arrest vomiting, warm lung cough-relieving, solving toxin of fish and crab, antidote poison;Suitable for catching cold, having a headache,
Phlegm and retained fluid, cough, gastrofrigid vomiting;It is anxious that it is drunk with ginger decoction being subjected to that ice and snow, water is wet, after cold invasion and attack, blood can be promoted, disperse cold
It is evil;Ginger contains pungent and fragrance ingredient, and piquancy component is the " zingerone, with good suppression in a kind of armaticity stearopten
Bacterium acts on;
Frutus cnidii:Frutus cnidii belongs to attacks poison, desinsection, antipruritic;Removing toxic substances desinsection, eliminating dampness wind-dispelling;Control eczema of vulva, married woman outward
Pruritus vulvae, trichomonas vaginitis, eczema mange, cold-dampness under band, arthritis with fixed pain caused by dampness pain in the back, impotence due to deficiency of the kidney, uterus cold infertile;
Ching-chieh:Inducing diaphoresis dissipates wind, promoting eruption;For catching a cold, having a headache, measles, rubella, sore from the beginning of;
It is windproof:For cold headache, rubella itch;Control exterior syndrome due to wind-cold, headache bodily pain, aversion to wind and cold person, Chang Peiwu schizonepeta, Qiang
Work, levisticum etc.;Diseases caused by external factors rheumatism is controlled, headache is such as wrapped up in, body weight acroaesthesia person, is equal to use with notopterygium root, Jehol Ligusticum Rhizome;Control rubella itch, many compatibilities
Kuh-seng, schizonepeta, Radix Angelicae Sinensis etc.;
Notopterygium root:Dissipate exterior cold, wind-damp dispelling, sharp joint, analgesic;Master catch cold, lossless, mimeograph cold-dampness numbness of having a headache, geomantic omen float
Swollen, sore swollen toxin;For impotence and seminal emission, enuresis frequent micturition, waist and knee crymodynia, deficiency of the kidney and dyspnea, Diarrhoea;External application curing vitiligo, spot
It is bald;Relieving exterior syndrome and dispelling cold, expelling wind and eliminating dampness, analgesic;
Corter pseudolaricis:It is desinsection, antipruritic;Control mange itch;The organic acid of corter pseudolaricis, ethanol extract and benzene medicinal extract, to common
10 kinds of pathomycetes have certain antibacterial action, to trichophyton schoenleini, acrothesium floccosum, the small gemma tinea bacterium of rust, stone
Cream sample sporidiole bacteria and Candida albicans are have bactericidal action;
Azedarach:Heat-clearing, eliminating dampness, desinsection;Root skin powder tune vinegar can control mange, and making ointment with chinaberry can control favus of the scalp.
Specific embodiment
The present invention is made with reference to specific embodiment further explain.
Embodiment one
A kind of herbal composite for treating tinea pedis proposed by the present invention, including following weight portion raw material:15 parts of Chinese prickly ash,
14 parts of ginger, 18 parts of frutus cnidii, 24 parts of ching-chieh, windproof 12 parts, 18 parts of notopterygium root, 12 parts of corter pseudolaricis, 12 parts of azedarach, tween
800.8 parts, 1.2 parts of alumen, 0.5 part of borax, 1 part of borneol.
Its preparation method, comprises the following steps:
S1, the Chinese prickly ash of preferably described proportion, ginger, frutus cnidii, ching-chieh, windproof, notopterygium root, corter pseudolaricis, azedarach, tween
80th, borax, alumen and borneol are standby;
S2, the Chinese prickly ash by step S1, ginger, frutus cnidii are added in No. 1 Chinese medicine extracting tank, add above-mentioned Chinese medicine total
After the water immersion 1.8h of 8 times of amount, high temperature decocts 9h, obtains volatile oil A and extract solution B;
S3, the ching-chieh in step S1, windproof, notopterygium root, corter pseudolaricis, azedarach are added in No. 2 Chinese medicine extracting tanks, plus
After the water immersion 1.8h of enter above-mentioned Chinese medicine total amount 8 times, high temperature decocts 9h, obtains extract solution C;
S4, the extract solution C of gained in the extract solution B and step S3 of gained in step S2 is merged, add 3 times of the concentration to be
75% medical ethanol, after being stirred with the rotating speed of 300r/min, stands 22h, filters to take supernatant D;
S5, the borax by step S1, alumen and borneol are dissolved in the supernatant D of gained in step S4, add step S2
The volatile oil A and Tween 80 of gained, are fully ground 3 times, and 6min is ground every time, and after grinding is uniform, quantitative separating is obtained final product.
Embodiment two
A kind of herbal composite for treating tinea pedis proposed by the present invention, including following weight portion raw material:20 parts of Chinese prickly ash,
12 parts of ginger, 15 parts of frutus cnidii, 20 parts of ching-chieh, windproof 10 parts, 15 parts of notopterygium root, 11 parts of corter pseudolaricis, 8 parts of azedarach, tween
800.5 parts, 2 parts of alumen, 0.8 part of borax, 1.5 parts of borneol.
Its preparation method, comprises the following steps:
S1, the Chinese prickly ash of preferably described proportion, ginger, frutus cnidii, ching-chieh, windproof, notopterygium root, corter pseudolaricis, azedarach, tween
80th, borax, alumen and borneol are standby;
S2, the Chinese prickly ash by step S1, ginger, frutus cnidii are added in No. 1 Chinese medicine extracting tank, add above-mentioned Chinese medicine total
After the water immersion 1.2h of 10 times of amount, high temperature decocts 12h, obtains volatile oil A and extract solution B;
S3, the ching-chieh in step S1, windproof, notopterygium root, corter pseudolaricis, azedarach are added in No. 2 Chinese medicine extracting tanks, plus
After the water immersion 1.2h of enter above-mentioned Chinese medicine total amount 10 times, high temperature decocts 12h, obtains extract solution C;
S4, the extract solution C merging by gained in the extract solution B and step S3 of gained in step S2, add 2.9 times of concentration
It is 75% medical ethanol, after being stirred with the rotating speed of 280r/min, stands 28h, filters to take supernatant D;
S5, the borax by step S1, alumen and borneol are dissolved in the supernatant D of gained in step S4, add step S2
The volatile oil A and Tween 80 of gained, are fully ground 2 times, and 8min is ground every time, and after grinding is uniform, quantitative separating is obtained final product.
Embodiment three
A kind of herbal composite for treating tinea pedis proposed by the present invention, including following weight portion raw material:12 parts of Chinese prickly ash,
16 parts of ginger, 20 parts of frutus cnidii, 22 parts of ching-chieh, windproof 11 parts, 16 parts of notopterygium root, 15 parts of corter pseudolaricis, 10 parts of azedarach, tween
800.3 parts, 3 parts of alumen, 1 part of borax, 2 parts of borneol.
Its preparation method, comprises the following steps:
S1, the Chinese prickly ash of preferably described proportion, ginger, frutus cnidii, ching-chieh, windproof, notopterygium root, corter pseudolaricis, azedarach, tween
80th, borax, alumen and borneol are standby;
S2, the Chinese prickly ash by step S1, ginger, frutus cnidii are added in No. 1 Chinese medicine extracting tank, add above-mentioned Chinese medicine total
After the water immersion 2h of 7.5 times of amount, high temperature decocts 8h, obtains volatile oil A and extract solution B;
S3, the ching-chieh in step S1, windproof, notopterygium root, corter pseudolaricis, azedarach are added in No. 2 Chinese medicine extracting tanks, plus
After the water immersion 2h of enter above-mentioned Chinese medicine total amount 7.5 times, high temperature decocts 8h, obtains extract solution C;
S4, the extract solution C merging by gained in the extract solution B and step S3 of gained in step S2, add 3.2 times of concentration
It is 75% medical ethanol, after being stirred with the rotating speed of 320r/min, stands 20h, filters to take supernatant D;
S5, the borax by step S1, alumen and borneol are dissolved in the supernatant D of gained in step S4, add step S2
The volatile oil A and Tween 80 of gained, are fully ground 4 times, and 5min is ground every time, and after grinding is uniform, quantitative separating is obtained final product.
Example IV
A kind of herbal composite for treating tinea pedis proposed by the present invention, including following weight portion raw material:18 parts of Chinese prickly ash,
13 parts of ginger, 12 parts of frutus cnidii, 30 parts of ching-chieh, windproof 15 parts, 22 parts of notopterygium root, 10 parts of corter pseudolaricis, 15 parts of azedarach, tween
800.6 parts, 1.5 parts of alumen, 0.6 part of borax, 1.2 parts of borneol.
Its preparation method, comprises the following steps:
S1, the Chinese prickly ash of preferably described proportion, ginger, frutus cnidii, ching-chieh, windproof, notopterygium root, corter pseudolaricis, azedarach, tween
80th, borax, alumen and borneol are standby;
S2, the Chinese prickly ash by step S1, ginger, frutus cnidii are added in No. 1 Chinese medicine extracting tank, add above-mentioned Chinese medicine total
After the water immersion 1h of 10.5 times of amount, high temperature decocts 10h, obtains volatile oil A and extract solution B;
S3, the ching-chieh in step S1, windproof, notopterygium root, corter pseudolaricis, azedarach are added in No. 2 Chinese medicine extracting tanks, plus
After the water immersion 1h of enter above-mentioned Chinese medicine total amount 10.5 times, high temperature decocts 10h, obtains extract solution C;
S4, the extract solution C merging by gained in the extract solution B and step S3 of gained in step S2, add 2.8 times of concentration
It is 75% medical ethanol, after being stirred with the rotating speed of 260r/min, stands 30h, filters to take supernatant D;
S5, the borax by step S1, alumen and borneol are dissolved in the supernatant D of gained in step S4, add step S2
The volatile oil A and Tween 80 of gained, are fully ground 2 times, and 8min is ground every time, and after grinding is uniform, quantitative separating is obtained final product.
Embodiment five
A kind of herbal composite for treating tinea pedis proposed by the present invention, including following weight portion raw material:10 parts of Chinese prickly ash,
15 parts of ginger, 10 parts of frutus cnidii, 28 parts of ching-chieh, windproof 14 parts, 20 parts of notopterygium root, 14 parts of corter pseudolaricis, 14 parts of azedarach, tween
800.4 parts, 2.5 parts of alumen, 0.9 part of borax, 1.8 parts of borneol.
Its preparation method, comprises the following steps:
S1, the Chinese prickly ash of preferably described proportion, ginger, frutus cnidii, ching-chieh, windproof, notopterygium root, corter pseudolaricis, azedarach, tween
80th, borax, alumen and borneol are standby;
S2, the Chinese prickly ash by step S1, ginger, frutus cnidii are added in No. 1 Chinese medicine extracting tank, add above-mentioned Chinese medicine total
After the water immersion 1.5h of 9.5 times of amount, high temperature decocts 11h, obtains volatile oil A and extract solution B;
S3, the ching-chieh in step S1, windproof, notopterygium root, corter pseudolaricis, azedarach are added in No. 2 Chinese medicine extracting tanks, plus
After the water immersion 1.5h of enter above-mentioned Chinese medicine total amount 9.5 times, high temperature decocts 11h, obtains extract solution C;
S4, the extract solution C merging by gained in the extract solution B and step S3 of gained in step S2, add 3.1 times of concentration
It is 75% medical ethanol, after being stirred with the rotating speed of 290r/min, stands 25h, filters to take supernatant D;
S5, the borax by step S1, alumen and borneol are dissolved in the supernatant D of gained in step S4, add step S2
The volatile oil A and Tween 80 of gained, are fully ground 3 times, and 6min is ground every time, and after grinding is uniform, quantitative separating is obtained final product.
The herbal composite of the treatment tinea pedis prepared in the embodiment of the present invention one~five is Traditional Chinese medicinal spray, every bottle of 15ml, 3
1 course for the treatment of of bottle, is sprayed on affected part and footgear and contact towel sooner or later daily;The present invention has been randomly selected with foot odour, pin bitterly
Itch, the serious tinea pedis patient 500 of foot's erosionization water, be divided into 5 groups, every group of patient 100 uses the embodiment of the present invention respectively
In one~five prepare Traditional Chinese medicinal spray, using 1~3 course for the treatment of after, cure rate is as follows:
Embodiment | One | Two | Three | Four | Five |
Cure rate (%) | 92.1 | 89.7 | 95.3 | 90.5 | 93.2 |
The above, the only present invention preferably specific embodiment, but protection scope of the present invention is not limited thereto,
Any one skilled in the art the invention discloses technical scope in, technology according to the present invention scheme and its
Inventive concept is subject to equivalent or change, should all be included within the scope of the present invention.
Claims (9)
1. a kind of herbal composite for treating tinea pedis, it is characterised in that the raw material including following weight portion:8~20 parts of Chinese prickly ash,
12~16 parts of ginger, 10~20 parts of frutus cnidii, 18~30 parts of ching-chieh, windproof 10~15 parts, 12~30 parts of notopterygium root, corter pseudolaricis 10
~15 parts, 8~15 parts of azedarach, 0.3~0.8 part of Tween 80,1~3 part of alumen, 0.5~1 part of borax, 0.8~2 part of borneol.
2. a kind of herbal composite for treating tinea pedis according to claim 1, it is characterised in that including following weight portion
Raw material:10~18 parts of Chinese prickly ash, 13~15 parts of ginger, 12~18 parts of frutus cnidii, 19.8~28 parts of ching-chieh, windproof 11~14
Part, 13.2~28 parts of notopterygium root, 11~14 parts of corter pseudolaricis, 10~14 parts of azedarach, 0.4~0.7 part of Tween 80, alumen 1.2~2.4
Part, 0.6~0.8 part of borax, 0.96~1.6 part of borneol.
3. a kind of herbal composite for treating tinea pedis according to claim 1, it is characterised in that including following weight portion
Raw material:15 parts of Chinese prickly ash, 14 parts of ginger, 15 parts of frutus cnidii, 24 parts of ching-chieh, windproof 12 parts, 22 parts of notopterygium root, 12 parts of corter pseudolaricis,
12 parts of azedarach, 0.5 part of Tween 80,2 parts of alumen, 0.7 part of borax, 1.2 parts of borneol.
4. a kind of herbal composite for treating tinea pedis according to claim 1, it is characterised in that the ching-chieh, anti-
Wind, the mass ratio of notopterygium root are 1.8~2:1:1.2~2.
5. a kind of herbal composite for treating tinea pedis according to claim 1, it is characterised in that the alumen, borax,
The mass ratio of borneol is 2~3:1:1.6~2.
6. a kind of herbal composite for treating tinea pedis according to claim 1, it is characterised in that the Chinese herbal medicine combination
Thing is Traditional Chinese medicinal spray.
7. a kind of preparation method of the herbal composite of the treatment tinea pedis according to any one of claim 1-6, its
It is characterised by, comprises the following steps:
S1, the Chinese prickly ash of preferably described proportion, ginger, frutus cnidii, ching-chieh, windproof, notopterygium root, corter pseudolaricis, azedarach, Tween 80,
Borax, alumen and borneol are standby;
S2, the Chinese prickly ash by step S1, ginger, frutus cnidii are added in No. 1 Chinese medicine extracting tank, after soaking 1~2h, high temperature
8~12h is decocted, volatile oil A and extract solution B is obtained;
S3, the ching-chieh in step S1, windproof, notopterygium root, corter pseudolaricis, azedarach are added in No. 2 Chinese medicine extracting tanks, add water leaching
After 1~2h of bubble, high temperature decocts 8~12h, obtains extract solution C;
S4, the extract solution C merging by gained in the extract solution B and step S3 of gained in step S2, add 2.8~3.2 times of second
Alcohol, after being stirred with the rotating speed of 260~320r/min, stands 20~30h, filters to take supernatant D;
S5, the borax by step S1, alumen and borneol are dissolved in the supernatant D of gained in step S4, add step S2 gained
Volatile oil A and Tween 80, be fully ground 2~4 times, 5~8min is ground every time, after grinding is uniform, quantitative separating is obtained final product.
8. the preparation method of a kind of herbal composite for treating tinea pedis according to claim 7, it is characterised in that described
In step S2 add water for Chinese prickly ash, ginger, 7.5~10.5 times of frutus cnidii total amount;Amount of water in step S3 is ching-chieh, prevents
Wind, notopterygium root, corter pseudolaricis, 7.5~10.5 times of azedarach total amount.
9. the preparation method of a kind of herbal composite for treating tinea pedis according to claim 7, it is characterised in that described
Ethanol in step S4 is medical ethanol that concentration is 75%.
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Cited By (1)
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CN108606372A (en) * | 2018-05-10 | 2018-10-02 | 傅炳文 | A kind of wet ankle socks dress of prevention tinea pedis |
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CN1292268A (en) * | 2000-04-24 | 2001-04-25 | 缪振兴 | Medicine for curing tinea unguium |
US20010005509A1 (en) * | 1999-02-11 | 2001-06-28 | Marie Harbeck | Foot cream composition |
CN104189477A (en) * | 2014-09-26 | 2014-12-10 | 洛阳华以生物工程有限公司 | Traditional Chinese medicine formula for treating barbiers |
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2017
- 2017-03-21 CN CN201710170741.8A patent/CN106822846A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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US20010005509A1 (en) * | 1999-02-11 | 2001-06-28 | Marie Harbeck | Foot cream composition |
CN1292268A (en) * | 2000-04-24 | 2001-04-25 | 缪振兴 | Medicine for curing tinea unguium |
CN104189477A (en) * | 2014-09-26 | 2014-12-10 | 洛阳华以生物工程有限公司 | Traditional Chinese medicine formula for treating barbiers |
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