CN110974932A - Chinese medicinal composition for preventing and treating fungal infection and repairing skin, and its preparation method - Google Patents

Chinese medicinal composition for preventing and treating fungal infection and repairing skin, and its preparation method Download PDF

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CN110974932A
CN110974932A CN201911423408.9A CN201911423408A CN110974932A CN 110974932 A CN110974932 A CN 110974932A CN 201911423408 A CN201911423408 A CN 201911423408A CN 110974932 A CN110974932 A CN 110974932A
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parts
skin
preventing
traditional chinese
fungal infection
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李富先
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Abstract

The invention discloses a traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect and a preparation method thereof, belonging to the technical field of traditional Chinese medicine preparations and being prepared from the following raw materials in parts by weight: 3-8 parts of mint, 8-12 parts of pepper, 20-30 parts of mother ginger, 15-25 parts of folium artemisiae argyi, 8-12 parts of semen cassiae, 8-12 parts of fructus kochiae, 8-12 parts of shrubalthea bark, 3-8 parts of fresh aloe and 3-8 parts of cacumen biotae. The traditional Chinese medicine composition has the functions of preventing and treating seasonal palm peeling, tinea manuum and foot skin, rash, scabies, skin itch and mosquito bite of fungal infection and repairing skin, and can quickly relieve, efficiently inhibit and effectively cure intractable and severe patients.

Description

Chinese medicinal composition for preventing and treating fungal infection and repairing skin, and its preparation method
Technical Field
The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for preventing and treating seasonal palm desquamation, hand and foot tinea, skin rash, scabies, skin itch and mosquito bites with a skin repairing effect and a preparation method thereof.
Background
Skin diseases are common diseases and frequently encountered diseases, have the characteristics of wide range, multiple types, long treatment period, difficult healing and the like, and bring various influences on psychology, physiology and life and work of patients.
According to the survey statistics of related departments in 2014, about 4.2 hundred million people suffer from skin diseases worldwide, wherein Chinese accounts for about 36 percent of 1.5 hundred million people. With the deterioration of climate and environment year by year, the number of patients still rises year by year, the degree of aging is worsened, the problems of living conditions, treatment cost and the like in the economic development lag zone and poverty zone are more serious, and the health, work and life of people are greatly influenced.
According to modern medical experiments, fungi are difficult to kill, can survive for a long time in an environment of about-6 ℃, and can not die within 10 minutes at a high temperature of 120 ℃; the toxicity can be maintained for more than 1 year when the composition is separated from living body.
Most patients with skin diseases or beriberi are treated by the fungus-inhibiting product, and the fungus is stopped after the symptoms are slightly improved, so that the fungus is not completely killed, the soil is seriously wrapped when the patients meet proper conditions, and the recurrence is serious.
According to the skin disease onset rule, skin diseases have different manifestations in different seasons, and the seasonal onset is obvious. The symptoms of fungal infection of hands and feet generally occur in the crossing of spring, summer, autumn and winter, the body and the head are frequently in the winter and spring, and the seasonal regularity of other rashes and skin inflammation is not obvious. The characteristics of the skin diseases are closely related to the life rule, habit and constitution of people. All people should adjust the life habit rules and do personal hygiene and do hygiene protection when going out, so that the occurrence of diseases can be reduced.
At present, the products for treating fungal skin diseases in the market are full of precious and various types of Chinese medicines for oral administration and external use, western medicines and fig. But has no obvious and efficient cure for severe and long-term diseases, especially for severe tinea manuum and tinea pedis skin diseases, can not be cured radically, has relapse or high inefficiency, increases endless troubles and economic losses for the mind and body of patients, enables severe patients not to work normally and smoothly, and brings certain influence on the development of national economy.
Disclosure of Invention
The invention provides a traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect and a preparation method thereof, and solves the problem that the existing products for treating fungal skin diseases have no obvious and efficient cure for severe and long-term symptoms.
In order to solve the technical problem, the technical scheme of the invention is realized as follows:
the invention provides a traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect, which is prepared from the following raw materials in parts by weight: 3-8 parts of mint, 8-12 parts of pepper, 20-30 parts of mother ginger, 15-25 parts of folium artemisiae argyi, 8-12 parts of semen cassiae, 8-12 parts of fructus kochiae, 8-12 parts of shrubalthea bark, 3-8 parts of aloe and 3-8 parts of cacumen biotae.
A traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect is prepared from the following raw materials in parts by weight: 5 parts of mint, 10 parts of pepper, 25 parts of mother ginger, 20 parts of folium artemisiae argyi, 10 parts of semen cassiae, 10 parts of fructus kochiae, 10 parts of shrubalthea bark, 5 parts of fresh aloe and 5 parts of cacumen biotae.
Wherein, preferably, the mint, the ginger, the aloe and the cacumen biotae are fresh materials; the pepper, the folium artemisiae argyi, the semen cassiae, the fructus kochiae and the shrubalthea bark are processed traditional Chinese medicinal materials.
A preparation method of a traditional Chinese medicine composition with functions of preventing and treating fungal infection and repairing skin comprises the following preparation steps according to the pharmacological characteristics of various medicinal materials:
(1) squeezing fresh and clean herba Menthae, folium Platycladi, rhizoma Zingiberis recens and fresh Aloe by wall breaking process, soaking in medical ethanol with same amount, soaking in ethanol for 7 days, and collecting filtrate;
(2) taking pepper, folium artemisiae argyi, semen cassiae, fructus kochiae and shrubalthea bark, adding 2 times of purified water, soaking for 1 hour, performing wall breaking process, decocting with slow fire for 30 minutes, and taking filtrate;
(3) and (3) mixing the stock solution obtained in the step (1) with the filtrate obtained in the step (2), uniformly stirring, and purifying by using a centrifugal technology to obtain the preparation.
Wherein, preferably, the step (1) adopts 75% pure grain medical ethanol.
Wherein, preferably, the following steps are further included after the step (3): standing the prepared preparation in a fine filtration storage container for 5 days, and filling in a PET bottle for avoiding ultraviolet light to obtain the finished product.
The efficacy of each component in the formula is as follows:
mint: the cool nature and flavor pungent in the liver and lung meridians, pungent and cool in nature and relieving exterior syndrome, dispelling wind, dissipating heat and promoting eruption, resisting bacteria and relieving itching, promoting percutaneous absorption, and stimulating dermal cell division and growth to regenerate epidermis.
Chinese prickly ash: warm in nature, pungent in flavor, entering spleen, stomach and kidney meridians; modern medical research shows that the pepper contains volatile oil components such as limonene, myrcene, and elagic alcohol, and alkaloids components such as Qingdatoxine and dehydroenteron, and the volatile oil has certain inhibiting and killing effects on 11 kinds of ringworm and 4 kinds of deep fungi and scabies, and has the effects of relieving pain, resisting bacteria, killing scabies and the like.
Mother ginger: it is warm in nature and pungent in flavor, entering lung, stomach and spleen meridians. Modern pharmacological research shows that the extract has the functions of resisting bacteria, resisting cancer, resisting oxidation and resisting aging, and the extract has obvious effect of inhibiting dermatophytes.
Folium artemisiae argyi: the medicine has warm and bitter taste, enters liver, spleen and kidney channels, has the effects of aromatic warmness, dispelling cold, relieving pain, reducing dampness and killing parasites, and has broad-spectrum antibacterial and antiviral effects, has the effects of inhibiting and killing various bacteria and dermatophytes when being externally used, and can be used for treating eczema, scabies, tinea, dampness and itching.
Cassia seed: the water extract has the functions of clearing heat, purging fire and resisting bacteria, has the function of inhibiting various pathogenic skin fungi, and can be used for controlling the spread of ringworm sores by matching.
The preparation method comprises the following steps of (1) preparing broom cypress fruit: the study shows that the water-soaking agent has an inhibitory effect on dermatophytes such as yellow ringworm, Odong small-flowered spore ringworm, small-flowered rust ringworm, small-flowered woolly spore ringworm, and Nocardia stellatoides. It can be used for treating skin pruritus, urticaria, eczema, etc.
And (3) shrubalthea bark: has mild property, sweet and bitter taste, enters liver, spleen and large intestine channels, clears heat, promotes diuresis, kills parasites and relieves itching, and is externally used for tinea corporis, skin scabies, tinea pedis, eczema scroti and the like.
Aloe vera: the cold nature and the bitter taste enter the liver channel of the large intestine and stomach, the liver heat is cleared out to resist bacteria, diminish inflammation and kill parasites, the damp tinea is externally treated, the wound healing is promoted and the skin is protected.
Cacumen biotae: the cold-natured bitter taste enters liver, lung and spleen channels, clears heat, cools blood, dispels wind, promotes diuresis, and has fragrant smell of cooling blood, stopping bleeding, resisting bacteria and diminishing inflammation.
In the formula, the ginger and the folium artemisiae argyi are taken as monarch drugs and mainly used for resisting and inhibiting bacteria; the pepper is a ministerial drug and can permeate skin to kill deep fungi; semen Cassiae, Kochiae fructus, cortex Hibisci are adjuvant drugs, can inhibit bacteria and can control the focus spread; the mint, the aloe and the cacumen biotae are used as guiding medicaments, and have the effects of relieving exterior syndrome, penetrating skin, repairing skin, harmonizing medicament smell and the like, so that the effect of directly reaching the interior of the skin by the medicament is accelerated, the skin is repaired after healing, scars are avoided, and the fragrance degree of the preparation is increased.
The traditional Chinese medicine composition has the functions of preventing and treating seasonal palm peeling, tinea manuum and foot skin, rash, scabies, skin itch and mosquito bite of fungal infection and repairing skin, and can effectively inhibit, quickly relieve and effectively cure intractable and severe patients.
When the hand-washing liquid is used on the hand, a proper amount of the liquid is sprayed on the affected part of the hand, the hand is kneaded until the hand is slightly hot to accelerate liquid permeation, the liquid is not less than 8 times in the morning and evening every day, the effect is obvious in 5-7 days, and the service life of a patient needs to be prolonged for a long time.
The foot bath liquid is used by feet, a proper amount of the liquid is sprayed on an affected part when the foot bath liquid is taken up in the morning and in the noon break in daily use, a proper amount of the liquid is poured into a plastic foot sleeve before sleeping at night and is placed in a foot basin, warm water with the temperature of 50-60 ℃ is poured into the foot basin, the feet are placed in the plastic foot sleeve to be heated and soaked for 15-20 minutes, obvious inhibition is realized in 3-5 days, the effect is realized in 7-10 days, and the service life.
The skin itch-relieving lotion is used for treating skin diseases of other parts of a body, can be sprayed on affected parts at any time in daily life if the skin is uncomfortable, and can be kneaded and dried by hands, and the skin itch can be obviously inhibited after being sprayed for a plurality of times without uncomfortable feeling. If the existing face-wound patients with serious skin need to use for a long time for many times every day, the excellent treatment effect can be achieved.
The invention has the beneficial effects that:
1. the Chinese medicinal composition is prepared from pure plants, does not contain hormones or antibiotics, has no harm or damage to human bodies and skins, and is safe to use.
2. Scientific formula, advanced processing and preparation process, rapid transdermal sterilization of deep fungi by applying various plant characteristics and adopting wall-breaking processing technology and extraction process, and rapid and efficient action.
3. Combines the traditional and modern Chinese medicine theories and the medicine property action characteristics with the characteristics of human body symptoms, has reasonable compatibility, complete and complete formula and wide antibacterial and bacteriostatic effects, and effectively cures various skin problems. Penetrate into skin to promote percutaneous absorption
4. In the formula, the mint emitted by the skin can expand skin pores, so that the efficacy of the mint can reach dermal tissues through the epidermis to promote transdermal absorption and quickly kill pathogenic bacteria to improve the curative effect, the aloe has the skin repairing effect and the effect of promoting skin healing, simultaneously has the effect of inhibiting and killing various fungal viruses, carries out omnibearing, multi-angle and deep treatment and repair on various symptoms of the skin, ensures that a patient can be treated accurately, efficiently and quickly, and avoids the patient from suffering from running pain caused by property loss.
5. The use is safe without contraindication, and the medicine can be used at any time and any place without influence on life and work.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The embodiment provides a traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect, which is prepared from the following raw materials in parts by weight: 5 parts of mint, 10 parts of pepper, 25 parts of mother ginger, 20 parts of folium artemisiae argyi, 10 parts of semen cassiae, 10 parts of fructus kochiae, 10 parts of shrubalthea bark, 5 parts of fresh aloe and 5 parts of cacumen biotae.
Wherein the mint, the ginger, the aloe and the cacumen biotae are fresh materials; the pepper, the folium artemisiae argyi, the semen cassiae, the fructus kochiae and the shrubalthea bark are processed traditional Chinese medicinal materials.
The preparation method of the traditional Chinese medicine composition for preventing and treating fungal infection and having the skin repair effect comprises the following preparation steps according to the pharmacological characteristics of various medicinal materials:
(1) squeezing fresh and clean herba Menthae, folium Platycladi, rhizoma Zingiberis recens and fresh Aloe by wall breaking process, soaking in 75% pure grain medical ethanol for ethanol extraction for 7 days, and collecting filtrate;
(2) taking pepper, folium artemisiae argyi, semen cassiae, fructus kochiae and shrubalthea bark, adding 2 times of purified water, soaking for 1 hour, performing wall breaking process, decocting with slow fire for 30 minutes, and taking filtrate;
(3) mixing the stock solution obtained in the step (1) and the filtrate obtained in the step (2), uniformly stirring, and purifying by using a centrifugal technology to obtain a preparation;
(4) standing the prepared preparation in a fine filtration storage container for 5 days, and filling in a PET bottle for avoiding ultraviolet light to obtain the finished product.
Example 2
The embodiment provides a traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect, which is prepared from the following raw materials in parts by weight: 3 parts of mint, 12 parts of pepper, 20 parts of mother ginger, 25 parts of folium artemisiae argyi, 8 parts of semen cassiae, 12 parts of fructus kochiae, 8 parts of shrubalthea bark, 8 parts of fresh aloe and 3 parts of cacumen biotae.
Wherein the mint, the ginger, the aloe and the cacumen biotae are fresh materials; the pepper, the folium artemisiae argyi, the semen cassiae, the fructus kochiae and the shrubalthea bark are processed traditional Chinese medicinal materials.
The preparation method of the traditional Chinese medicine composition for preventing and treating fungal infection and having the skin repair effect comprises the following preparation steps according to the pharmacological characteristics of various medicinal materials:
(1) squeezing fresh and clean herba Menthae, folium Platycladi, rhizoma Zingiberis recens and fresh Aloe by wall breaking process, soaking in 75% pure grain medical ethanol for ethanol extraction for 7 days, and collecting filtrate;
(2) taking pepper, folium artemisiae argyi, semen cassiae, fructus kochiae and shrubalthea bark, adding 2 times of purified water, soaking for 1 hour, performing wall breaking process, decocting with slow fire for 30 minutes, and taking filtrate;
(3) mixing the stock solution obtained in the step (1) and the filtrate obtained in the step (2), uniformly stirring, and purifying by using a centrifugal technology to obtain a preparation;
(4) standing the prepared preparation in a fine filtration storage container for 5 days, and filling in a PET bottle for avoiding ultraviolet light to obtain the finished product.
Example 3
The embodiment provides a traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect, which is prepared from the following raw materials in parts by weight: 8 parts of mint, 8 parts of pepper, 30 parts of mother ginger, 15-25 parts of folium artemisiae argyi, 8 parts of semen cassiae, 12 parts of fructus kochiae, 8 parts of shrubalthea bark, 8 parts of fresh aloe and 3 parts of cacumen biotae.
Wherein the mint, the ginger, the aloe and the cacumen biotae are fresh materials; the pepper, the folium artemisiae argyi, the semen cassiae, the fructus kochiae and the shrubalthea bark are processed traditional Chinese medicinal materials.
The preparation method of the traditional Chinese medicine composition for preventing and treating fungal infection and having the skin repair effect comprises the following preparation steps according to the pharmacological characteristics of various medicinal materials:
(1) squeezing fresh and clean mint, cacumen biotae, ginger and fresh aloe by a wall breaking process, soaking the squeezed mint, cacumen biotae, ginger and aloe in 75 percent of pure grain medical ethanol for alcohol leaching for 7 days, and taking filtrate;
(2) taking pepper, folium artemisiae argyi, semen cassiae, fructus kochiae and shrubalthea bark, adding 2 times of purified water, soaking for 1 hour, performing wall breaking process, decocting with slow fire for 30 minutes, and taking filtrate;
(3) mixing the stock solution obtained in the step (1) and the filtrate obtained in the step (2), uniformly stirring, and purifying by using a centrifugal technology to obtain a preparation;
(4) standing the prepared preparation in a fine filtration storage container for 5 days, and filling in a PET bottle for avoiding ultraviolet light to obtain the finished product.
Example 4
The embodiment provides a traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect, which is prepared from the following raw materials in parts by weight: 4 parts of mint, 11 parts of pepper, 22 parts of mother ginger, 23 parts of folium artemisiae argyi, 9 parts of semen cassiae, 11 parts of fructus kochiae, 9 parts of shrubalthea bark, 4 parts of fresh aloe and 6 parts of cacumen biotae.
Wherein the mint, the ginger, the aloe and the cacumen biotae are fresh materials; the pepper, the folium artemisiae argyi, the semen cassiae, the fructus kochiae and the shrubalthea bark are processed traditional Chinese medicinal materials.
The preparation method of the traditional Chinese medicine composition for preventing and treating fungal infection and having the skin repair effect comprises the following preparation steps according to the pharmacological characteristics of various medicinal materials:
(1) squeezing fresh and clean herba Menthae, folium Platycladi, rhizoma Zingiberis recens and fresh Aloe by wall breaking process, soaking in 75% pure grain medical ethanol for ethanol extraction for 7 days, and collecting filtrate;
(2) taking pepper, folium artemisiae argyi, semen cassiae, fructus kochiae and shrubalthea bark, adding 2 times of purified water, soaking for 1 hour, performing wall breaking process, decocting with slow fire for 30 minutes, and taking filtrate;
(3) mixing the stock solution obtained in the step (1) and the filtrate obtained in the step (2), uniformly stirring, and purifying by using a centrifugal technology to obtain a preparation;
(4) standing the prepared preparation in a fine filtration storage container for 5 days, and filling in a PET bottle for avoiding ultraviolet light to obtain the finished product.
Example 5
The embodiment provides a traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect, which is prepared from the following raw materials in parts by weight: 7 parts of mint, 9 parts of pepper, 28 parts of mother ginger, 18 parts of folium artemisiae argyi, 11 parts of semen cassiae, 9 parts of fructus kochiae, 11 parts of shrubalthea bark, 5 parts of fresh aloe and 7 parts of cacumen biotae.
Wherein the mint, the ginger, the aloe and the cacumen biotae are fresh materials; the pepper, the folium artemisiae argyi, the semen cassiae, the fructus kochiae and the shrubalthea bark are processed traditional Chinese medicinal materials.
The preparation method of the traditional Chinese medicine composition for preventing and treating fungal infection and having the skin repair effect comprises the following preparation steps according to the pharmacological characteristics of various medicinal materials:
(1) squeezing fresh and clean herba Menthae, folium Platycladi, rhizoma Zingiberis recens and fresh Aloe by wall breaking process, soaking in 75% pure grain medical ethanol for ethanol extraction for 7 days, and collecting filtrate;
(2) taking pepper, folium artemisiae argyi, semen cassiae, fructus kochiae and shrubalthea bark, adding 2 times of purified water, soaking for 1 hour, performing wall breaking process, decocting with slow fire for 30 minutes, and taking filtrate;
(3) mixing the stock solution obtained in the step (1) and the filtrate obtained in the step (2), uniformly stirring, and purifying by using a centrifugal technology to obtain a preparation;
(4) standing the prepared preparation in a fine filtration storage container for 5 days, and filling in a PET bottle for avoiding ultraviolet light to obtain the finished product.
Clinical data
The clinical test of the total 100 cases meets the diagnosis standard of fungal dermatosis, specifically palm desquamation, tinea manuum and pedis, skin rash, scabies and skin itch caused by fungal infection. 56 women and 44 men; the age is 18-60 years, and the average age is 35.26 years; the disease course is 4 weeks to 6 years, and the average is 2.12 years; patients were randomized into 2 groups: control group and treatment group, 50 control group, and 50 treatment group.
The treatment method comprises the following steps:
the treatment group adopts the traditional Chinese medicine composition for preventing and treating fungal infection and having the skin repairing effect in the embodiment 1 for treatment, and the treatment group is continuously applied for 10 days;
when the hand is used, a proper amount of the Chinese medicinal composition is sprayed on affected parts of hands, and the hands are kneaded until the hands are slightly hot to accelerate liquid permeation, wherein the time of the kneading is not less than 8 times per day in the morning and at night;
the foot bath liquid is used for feet, a proper amount of the liquid is sprayed on an affected part when the foot bath liquid is taken up in the morning and in the afternoon break in daily use, a proper amount of the liquid is poured into a plastic foot sleeve before sleeping at night and is arranged in a foot basin, warm water with the temperature of 50-60 ℃ is poured into the foot basin, and the feet are placed in the plastic foot sleeve to be heated and soaked for 15-20 minutes;
the product can be applied to affected parts for treating skin diseases at other parts of human body, and can be applied by rubbing with hands for not less than 5 times daily.
The control group is treated with Daktarin for 10 days, and applied to the cleaned affected part 1 time in the morning and evening,
observation indexes are as follows: the patient is observed daily for changes in skin complexion, skin changes at fungal sites, and other symptoms and signs.
Treatment efficacy evaluation criteria and results: the treatment effect evaluation standard is that all observation indexes are recovered to be normal; the obvious effect means that the disease condition is obviously improved; the disease condition is improved but not obvious; the ineffectiveness means that the disease condition is not improved or aggravated, and the observation index is not obviously improved or aggravated. The results are shown in the following table:
group of General case Recovery method Show effect Is effective Invalidation The total effective rate%
Control group 50 15 20 10 5 90%
Treatment group 50 12 18 8 12 76%
The data show that the curative effect of the treatment group is obviously higher than that of the control group, the total effective rate is also obviously higher than that of the control group, and when the traditional Chinese medicine composition is used for feet, the foot is obviously inhibited for 3 to 5 days, and the effect is obvious for 7 to 10 days; when used on hands, the composition has obvious effect in 5-7 days.
In addition, the formula of the invention effectively inhibits and eliminates the symptoms through repeated trial of various symptoms for many people in recent years. Can take effect and cure the slight symptoms after short-term use, and can take effect and cure the serious symptoms without obvious relapse after long-term persistence and repeated use for a plurality of times every day. Has high-efficiency healing effect on severe seasonal tinea manuum desquamation.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (6)

1. A traditional Chinese medicine composition for preventing and treating fungal infection and having a skin repairing effect is characterized by being prepared from the following raw materials in parts by weight: 3-8 parts of mint, 8-12 parts of pepper, 20-30 parts of mother ginger, 15-25 parts of folium artemisiae argyi, 8-12 parts of semen cassiae, 8-12 parts of fructus kochiae, 8-12 parts of shrubalthea bark, 3-8 parts of fresh aloe and 3-8 parts of cacumen biotae.
2. The traditional Chinese medicine composition for preventing and treating fungal infection and having skin repair effect according to claim 1 is characterized by being prepared from the following raw materials in parts by weight: 5 parts of mint, 10 parts of pepper, 25 parts of mother ginger, 20 parts of folium artemisiae argyi, 10 parts of semen cassiae, 10 parts of fructus kochiae, 10 parts of shrubalthea bark, 5 parts of fresh aloe and 5 parts of cacumen biotae.
3. The traditional Chinese medicine composition for preventing and treating fungal infection and having skin repair effect according to claim 1 or 2, characterized in that: the mint, the ginger, the aloe and the cacumen biotae are fresh materials; the pepper, the folium artemisiae argyi, the semen cassiae, the fructus kochiae and the shrubalthea bark are processed traditional Chinese medicinal materials.
4. A method for preparing a Chinese medicinal composition for preventing and treating fungal infection and repairing skin as claimed in any one of claims 1 to 3, which is characterized by comprising the following steps according to the pharmacological characteristics of each kind of medicinal materials:
(1) squeezing fresh and clean herba Menthae, folium Platycladi, rhizoma Zingiberis recens and fresh Aloe by wall breaking process, soaking in medical ethanol with same amount, soaking in ethanol for 7 days, and collecting filtrate;
(2) taking pepper, folium artemisiae argyi, semen cassiae, fructus kochiae and shrubalthea bark, adding 2 times of purified water, soaking for 1 hour, performing wall breaking process, decocting with slow fire for 30 minutes, and taking filtrate;
(3) and (3) mixing the stock solution obtained in the step (1) with the filtrate obtained in the step (2), uniformly stirring, and purifying by using a centrifugal technology to obtain the preparation.
5. The preparation method of the traditional Chinese medicine composition with the functions of preventing and treating fungal infection and repairing skin according to claim 4 is characterized by comprising the following steps: 75% pure grain medical ethanol is adopted in the step (1).
6. The preparation method of the traditional Chinese medicine composition with the functions of preventing and treating fungal infection and repairing skin according to claim 4 is characterized by comprising the following steps: the method also comprises the following steps after the step (3): standing the prepared preparation in a fine filtration storage container for 5 days, and filling in a PET bottle for avoiding ultraviolet light to obtain the finished product.
CN201911423408.9A 2019-12-31 2019-12-31 Chinese medicinal composition for preventing and treating fungal infection and repairing skin, and its preparation method Pending CN110974932A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111714601A (en) * 2020-08-09 2020-09-29 仲崇允 A Chinese medicinal composition for treating fungal infection

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111714601A (en) * 2020-08-09 2020-09-29 仲崇允 A Chinese medicinal composition for treating fungal infection

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