CN104510815B - Prevent and treat the Chinese medicine preparation of pork pig dermatitis - Google Patents

Prevent and treat the Chinese medicine preparation of pork pig dermatitis Download PDF

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CN104510815B
CN104510815B CN201410769528.5A CN201410769528A CN104510815B CN 104510815 B CN104510815 B CN 104510815B CN 201410769528 A CN201410769528 A CN 201410769528A CN 104510815 B CN104510815 B CN 104510815B
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parts
dermatitis
pig
medicine
pork pig
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CN104510815A (en
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杨晓天
石治华
庄海燕
黄祥良
江岸林
农丽荣
黄江峰
郑子胜
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GUANGXI ZHUANG AUTONOMOUS REGION WUXUAN LIVESTOCK BREEDING STATION
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GUANGXI ZHUANG AUTONOMOUS REGION WUXUAN LIVESTOCK BREEDING STATION
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams

Abstract

The invention discloses a kind of traditional Chinese medicine for outer use for preventing and treating pork pig dermatitis, it is characterised in that:The Chinese medicine preparation is made up of the Chinese medicine material of following parts by weight:10 parts of kuh-seng 5 part, 10 parts of the Radix Astragali 5 part, 30 parts of baeckea frutescen 20 part, 20 parts of margosa 15 part, 20 parts of Chinese wampee leaf 15 part, 30 parts of folium artemisiae argyi 20 part.It has effects that anti-inflammatory anti-itch, heat-clearing and damp-drying drug, antibacterial, except taking poison and growing muscle due, desinsection, antiallergy, inducing diuresis for removing edema, discharge fester and eliminate erythema, have significant curative effect for preventing and treating pork pig allergic dermatitis, bite dermatitis, exudative dermatitis, necrodermatitis.

Description

Prevent and treat the Chinese medicine preparation of pork pig dermatitis
Technical field
The present invention relates to Chinese herbal medicine preparation technology field, specially a kind of Chinese medicine preparation for preventing and treating pork pig dermatitis.
Background technology
Pigskin inflammation is a kind of inflammation of skin surface tissue, and also the deep tissues of skin are arrived in infringement sometimes, more because certain is pierced Swash caused:Pig house darkness humidity, poor hygienic, feed corruption, chemical drug, insect etc. stimulate skin;Or because indigestion, dimension A lack Weary grade can also cause dermatitis.Wherein using neuropathic and toxic reason as principal element.Pork pig dermatitis pathogenic factor and face Bed symptom is as follows:
Allergic dermatitis, by the dark humidity of pig house, bedding and padding are unclean, it is not in place even with mouldy grain trough to sterilize (Mycotoxin)Cause, depart from anaphylactogen, the state of an illness takes a turn for the better naturally, severe one infection causes exanthemv;Cut open inspection is without lymph nodes of body as a whole The lesion such as serosity swelling, tangent plane be faint yellow.Pig body is bitten place's skin and papule not of uniform size occurs, its itching triggered, Pig is caused constantly to dawdle, bite, hair comes off, the rotten to the corn surface of a wound occurs in epidermis, and has faint yellow diffusate.
Bite dermatitis, it is relevant with biting for various insect vectors;It is many with the position that bears a pretty, delicate skin such as auricle, eyelid, belly Hair;The different degrees of allergic reaction of performance, generally red edemous papule, with titillation, sick pig occurs rubbing wiping action.
Exudative dermatitis, are mainly caused by Staphylococcus hyicus, Staphylococcus hyicus be Gram-positive, conditioned pathogen, often It is lodged in skin, on mucous membrane, when the resistance reduction of animal or damaged skin, mucous membrane, germ is just taken advantage of a weak point.Exudative skin Inflammation, there is subacute or chronic point.In acute, infringement is seen first encloses near the eyes, nose, lip, and skin is presented red after gum and ear Color spot point, spot becomes big, can develop into bubble or warts.Due to skin, sweat and slurries are mutually mixed the oily to be formed and oozed out Thing makes skin become moist through quickly, greasy.Erythema is presented, and covers whole body, and the exudate of skin surface is thickening, and calloused skin seems It is drier.This stage is likely to occur the foul smell become sour.After incrustation comes off, expose coarse and height redness skin, pin Often there is erosion in portion's coronary band and heel.Infringement can be betided around eye conjunctiva, cause eyelid swelling, inter-adhesive.Affected animal is just Secret, visible diarrhoea is with becoming thin once in a while., often there is symptom death in 3~5 days in initially in dewatering symptom.Exudative dermatitis also with ripple And it is relevant to the kidney damage of renal plevis and renal tubule.After the big infection to 5 monthly age pigs of 6-10 week old is in chronic type more.Weanling pig is even You, which see, is dispersed in, rounded protuberance papule, in bronzing.In head, whelk is more, and trunk is rare.
Pig necrodermatitis, just, constitutional symptom is not obvious for disease, the rise of severe patient body temperature, and few food or appetite are useless absolutely, become thin, It is often lethal due to cachexia.Occur the big red papules of the grain of rice, frequent itch on skin surface first, papule developing deeply is The tubercle of dry scab, firmly swelling admittedly.Subsequent Subeschar tissue necrosis is festered and extended rapidly, forms cryptomere necrosis region, and sick portion loses hair or feathers, oozed Go out, skin color bleaches, the necrosis of stove inner tissue or dissolving, form lark or taupe brown stench wound liquid, last ulceration flows out, but Wound edge is uneven, and wound bottom is uneven;This necrosis region often occurs at 4 at~5, at many more than ten, or even spreads all over whole body.A small number of diseases Its lesion of pig can be caused as deep as muscle tendon, ligament and bone and belly perforation and chest perforation occur;Some acra corruption are de-; Some ear and tail dry necrosises;Last peeled off from its edge comes off.The multiple side for being born in pig of above-mentioned focus, buttocks and neck.
Pigskin inflammation is a kind of relatively common porcine skin disease, is often occurred in hot summer and autumn and winter.Pig suffers from after dermatitis, appetite Substantially decline, has a strong impact on growing for pig, and the morbidity later stage is presented diarrhoea, seriously lost flesh.It is weak small as treated not in time Pig turns into cad pig.Though the sick death rate is low, the incidence of disease is high, and the course of disease is long, and heavy economic losses is caused to pig industry.So how Can make the pork pig fast speed for suffering from dermatitis, it is high-quality prevented and treated, be also the target that those skilled in the art pursue always.At present, The externally applied drug of pigskin inflammation mainly has two classes used in the market, and one is:Western medicine preparation;Two are:Chinese and Western medicine composite preparation.In clinic There is following defect in use:Most of is antimicrobial class, antibiotic agents and ointments preparation.Long-term taking antimicrobial Class, pig has reformed into the carrier of a bacterium selection culture, and those germs for having escaped antibiotic can become with medicine resistance ability Strength pathogenic bacteria, even usually very common bacterium can also make a variation as super pathogenic bacteria.Once there is the machine for traveling to people Meeting, human body can not be low-grade.Another problem, antimicrobial can be also remained in pork, after people has eaten, just into indirect Victim.Although the drug matrices of antibioticses are easily absorbed by sick pig, medicine instant effect, overdose, prolonged abuse Antibiotic, not only causes the waste of medicine, increases cost payout;Toxic reaction, allergic reaction and double can also be triggered when serious Infection even causes pig dead.If antibiotic agents consumption is not enough, administration time is long, and preventive effect is not reached not only, And seriously induce bacterium generation drug resistance.The drug matrices of ointments are difficult to be absorbed by tissue, and the surface of a wound will necessarily be in dissolve shape State, is on the one hand easily caused bacterium infection, and another aspect influences the formation of last layer skin during tissue repair, causes the surface of a wound again Healing time extends, and part dermatitis externally applied drug has allergic reaction to the pork pig for suffering from dermatitis, causes obstinate, course of disease extension.
At present, the scorching medicine of in the market treatment pigskin is also more, and such as coating zinc ointment or celo imitate ointment and embrocates 3% first Base purple alcohol liquid;Or apply the liniment put on the skin and be made up of kerosene, camphor ball, carbolic acid and creosote;Or intramuscular injection antibiotic, such as salt sour soil Mycin parenteral solution;Or use Amoxicillin, terramycin or TMP synergistic sulfonamide spices;Or the strength produced using the animal husbandry of the Shandong sky Mycin, reinforcing(Pest poison health or qingwen baidu powder)Whole body is sprayed after drinking-water or spice, compound aldehyde sterilization dilution agent.These medicines are controlled Therapeutic effect is affirmative.But the drug matrices of ointment formulation class are difficult, by cortical tissue's absorption of pig, to cause obstinate, the course of disease Extension;Side effect that antimicrobial class, antiviral class, antibioticses and hormone medicine are brought is big, and cost payout is big, and effect is not yet It is very preferable.Producer is usually constructed with the demand for wishing to treat as early as possible after pork pig suffers from dermatitis, to release slight illness, recovers meat Pig normally grows.
Therefore, develop it is a kind of fast and effectively, low cost, with anti-inflammatory anti-itch, heat-clearing and damp-drying drug, antibacterial, except taking poison and growing muscle due, Desinsection, antiallergy, the traditional Chinese medicine for outer use for preventing and treating dermatitis of effect of inducing diuresis for removing edema is just necessary.
The content of the invention
The purpose of the present invention for above-mentioned prior art it is not enough and propose it is a kind of fast and effectively, low cost, have Anti-inflammatory anti-itch, heat-clearing and damp-drying drug, antibacterial, except taking poison and growing muscle due, desinsection, antiallergy, effect of inducing diuresis for removing edema, when having no toxic side effect, preventing and treating Between it is short, pork pig cortical tissue can be promoted to repair and prevent cortical tissue further by bacterium infection, skin, which is presented, to pork pig bursts Rotten and red papules or the tubercle for the dry scab for being by papule developing deeply, epidermis erosion and the preventing and treating for having the symptoms such as faint yellow diffusate Traditional Chinese medicine for outer use and preparation method thereof.
The present invention is realized using following technical scheme:
The traditional Chinese medicine for outer use of present invention preventing and treating pork pig dermatitis, is made up of the raw material of following parts by weight:
Kuh-seng 5-10;
Radix Astragali 5-10;
Baeckea frutescen 20-30;
Margosa 15-20;
Chinese wampee leaf 15-20;
Folium artemisiae argyi 20-30.
The present invention is made up of Chinese medicinal materials such as kuh-seng, the Radix Astragali, baeckea frutescen, margosa, Chinese wampee leaf, folium artemisiae argyis, with anti-inflammatory anti-itch, Heat-clearing and damp-drying drug, antibacterial, except taking poison and growing muscle due, desinsection, antiallergy, the effect of inducing diuresis for removing edema, thus for prevent and treat pork pig allergic dermatitis, Bite dermatitis, exudative dermatitis, necrodermatitis have significant curative effect.
Each medicine effective ingredient analysis of the traditional Chinese medicine for outer use Chinese medicine preparation of above-described preventing and treating pork pig dermatitis:
Kuh-seng,【Alias】Matrine, Chinese scholartree, water Chinese scholartree, Tu Chinese scholartrees, proud Chinese scholartree, wild Chinese scholartree, white stem;【Latin】Sophora flavescens;Fallen leaves fruticuli, high 1.5~3m, root is cylindric, and crust yellow-white, stem is upright, multi-branched, has longitudinal furrow;Sprout By thin hair, become afterwards hairless.Flavor efficacy:It is cold in nature, bitter;【Efficacy of Traditional Chinese Medicine】Sophora flavescens ait is bitter for perennial fallen leaves semishrub plant The root of ginseng, kuh-seng has the effect of anti-inflammation, has inhibitory action to Propiobacterium, staphylococcus aureus, Escherichia coli, Can antiallergy, analgesia;Kuh-seng bath can remove damp-heat in lower-JIAO, and desinsection is antipruritic, size occurs by the place's of biting skin to pig body The itching that the papule differed triggers has good mitigation;①《Haigoushen》:Control heat toxin wind, the raw sore of musculus cutaneus agitation, red leprosy eyebrow It is de-, it is main except big heat is drowsiness, crymodynia in abdomen is controlled, middle evil stomachache, except body is vexed, controls trusted subordinate's accumulation;②《The southern regions of the Yunnan Province book on Chinese herbal medicine》:Cool blood, it is antipyretic Poison, scabies leprosy, impetigo poison.Pruitus is treated, blood wind tinea sore, naughty white bits, discharging fresh blood stool is had blood in stool.Disappear wind, detumescence poison.【Function Cure mainly】Heat-clearing and damp-drying drug, desinsection, diuresis.For hematochezia, jaundice renal shutdown, eczema, wet sore, pruitus, wet poison sore mange Leprosy.
The Radix Astragali,【Alias】Cotton stilbene, astragalus, only mulberry, another name for Sichuan Province fat, hundred, hundred absorbent cotton, Huang Can, blood ginseng, people's rank;【English name】 Milkvetch Root 【Latin】Astragalus membranaceus (Fisch.) Bunge.;Perennial herb is high 50-100 centimetres;Flavor efficacy:Sweet, the tepor of property.Modern medicine study shows that the Radix Astragali has enhancing body's immunity, hidroschesis, profit Water is subsided a swelling, except taking poison and growing muscle due liver protection, diuresis, resisting stress, decompression and wide antibacterial action.【Chinese Herbs】1st, acute nephritis water It is swollen:For the void oedema caused by YANG QI deficiency, and often close and uses with tetrandra root, Poria cocos, the bighead atractylodes rhizome etc., side's such as Tetrandra and Astragalus Decoction;2、 Yang-energy is weak:Caved in for sore not diabrosis long, there is promotion diabrosis and limitation effect.Ulcer not penetrator long, often with pangolin, Spina gleditsiae, Radix Angelicae Sinensis, Ligusticum wallichii are with use;3rd, sore diabrosis:Do not close up long, there is the effect of promoting granulation and wound healing, often with honeysuckle flower, spina gleditsiae, Chinese violet Deng.Fester is cleaned, and is equal with Radix Codonopsis, Chinese cassia tree and is used.
Baeckea frutescen,【Latin】Baeckea frutescens L.;Dungarunga or shrub shape, Myrtaceae;Flavor efficacy: Cool in nature, bitter is pungent.Blood-activating analgetic, heat-clearing unit of weight measurement, about six liang poison, desinsection is antipruritic.Treatment heat is rushed down, heat gonorrhea, eczema, pruitus, mange.Ye Han Fenchanol etc., hyoscine controls cystitis, and washout controls dermatitis and eczema;Root, complete stool (baeckea frutescen):It is pungent, bitter, puckery, it is cool.Wind-dispelling is removed It is wet, removing toxic substances, diuresis, analgesic, it is antipruritic;①《Nanning City's medicine will》:Convergence, desinsection stops blooding, analgesic, myogenic.With washing sore, scabies Itch;②《Guangxi Chinese medicinal herbal》:There is diuresis promoting effect.Control bladder heat, skin hot gas.Decoct washing skin it is rotten itch, eczema.
Margosa,【Alias】Chinaberry(Herbal footpath), bitter Siberian cocklebur, FRUCTUS TOOSENDAN, Zhan wingceltises, chinaberry, pale reddish brown tree(Jiangsu), gloomy tree(Guangdong) 【Latin】Melia azedarach Linn.;Meliaceae deciduous tree plant;It is used as medicine with the leaf of plant and flower, bitter is cold in nature, Heat-clearing and damp-drying drug, desinsection is antipruritic, promoting qi circulation and relieving pain;With the fruit medicine of plant, bitter is cold in nature, slightly poisonous, promoting qi circulation and relieving pain, desinsection.
Chinese wampee leaf, takes passages《National Chinese herbal medicine compilation》.It is the leaf of clausenae Lansium, Calusena lansium【Latin】Clausena lansium (Lour.)Skeels,【Alias】The outermost layer of skin, oily plum;The blade of rutaceae Calusena lansium;【Nature and flavor】Leaf:It is bitter, pungent, put down; Root, core:It is bitter, pungent, tepor;Really:Sweet, acid, tepor.【Major function】Expelling wind to resolve the exterior, eliminating phlegm promoting the circulation of qi.Warm disease body heat is controlled, cough is roared Breathe heavily, inflatable stomachache, Huang is swollen, malaria, difficult urination, the effects such as heat toxin scabies leprosy.①《Book on Chinese herbal medicine asks former》:Dirty scale removal is solved, removing jaundice swells.② 《Fujian traditional herbal medicine》:Control productive cough asthma.③《Luchuan book on Chinese herbal medicine》:Yu Hangqi is dredged, analgesic is brought down a fever.Control inflatable stomachache, warm disease body heat. 4. Guangzhou army《Conventional Chinese herbal medicine handbook》:Expelling wind to resolve the exterior.Leaf:Inducing diaphoresis is radiated, qi-regulating and phlegm-dissipating.For prevent and treat influenza, Meningococal meningitis, malaria, cure cold heating.
Folium artemisiae argyi,【Alias】Ice platform(《You are young》), argy wormwood(《It is elegant》Guo Pu notes), doctor's grass(《Do not record》), moxibustion grass(《Increase is refined》), Chinese mugwort(《Chinese mugwort is passed》), yellow grass(《Detailed outline》), family Chinese mugwort(《Medical center bun will》), sweet tea Chinese mugwort(《Book on Chinese herbal medicine asks former》), the fluffy, Ai Peng of grass, wolf tail Wormwood artemisia, fragrant Chinese mugwort, Ye Liantou, A Jiai, Chen Ai, big wormwood, ash grass;【Latin】Artemisia argyi Levl. et Van.:Feverfew Chinese mugwort Artemisia argyi Levl. et Vant. dried leaf;Nature and flavor:Toil, temperature.①《Do not record》: Bitter, tepor is nontoxic.②《Tang materia medica》:It is raw cold, ripe heat.③《Detailed outline》:Bitter and pungent, raw temperature, ripe heat.【Major function】It is modern The pharmacological research of medical science shows that folium artemisiae argyi is a kind of medicine of broad-spectrum antibacterial antiviral, it have to a lot of viruses and bacteriums suppression and Lethal effect.Warming channel for arresting bleeding, eliminating cold to stop pain, wet down desinsection treats eczema, mange, carbuncle swells, the disease such as hemorrhoid.Moxibustion treatment all kinds of diseases and ailments.Folium artemisiae argyi In vitro to bacillus anthracis, Alpha-hemolytic streptococcus, B- Streptococcus hemolyticus, corynebacterium diphtheriae, bacillus pseudodiphthericus, lung diplococcoid, gold 10 kinds of gram-positive Aeromonas bacterias such as staphylococcus aureus, Staphylococcus citreus, staphylococcus aureus, hay bacillus all have anti- Bacterium acts on.
External application aqua or alcohol spray can be made in the traditional Chinese medicine for outer use of above-mentioned preventing and treating pork pig dermatitis.
The traditional Chinese medicine for outer use of preventing and treating pork pig dermatitis of the present invention can be used for treatment pork pig allergic dermatitis, bite Property dermatitis, solarized dermatitis, pig necrodermatitis.
The traditional Chinese medicine for outer use of preventing and treating pork pig dermatitis of the present invention is first in clinical treatment pork pig dermatitis project Step is on probation, and reflection is good, no obvious toxic-side effects.
The present invention treatment pork pig dermatitis external application aqua production method be by weight by dry kuh-seng, the Radix Astragali, Baeckea frutescen, margosa, Chinese wampee leaf, folium artemisiae argyi are broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, addition water is medicine 6-19 times of thing gross weight, boiled 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, clear liquid adds appropriate Preservative is bottled, and obtains external application aqua.
The present invention treatment pork pig dermatitis alcohol spray production method be by weight by dry kuh-seng, the Radix Astragali, Baeckea frutescen, margosa, Chinese wampee leaf, folium artemisiae argyi are broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, addition water is medicine 3-5 times of thing gross weight, it is boiled 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, according to weight 1:1 Ratio, clear liquid is added volumetric concentration 50-90% alcohol, and mixing, which is fitted into spray bottle, obtains product.
The beneficial effects of the invention are as follows:
1st, the present invention play anti-inflammatory anti-itch, discharge fester and eliminate erythema effect, have no toxic side effect, the preventing and treating time is short, Pork pig cortical tissue can be promoted to repair and prevent cortical tissue further by bacterium infection, exanthemv is presented to pork pig and red The tubercle of color papule or the dry scab for being by papule developing deeply, epidermis are rotten to the corn and have faint yellow diffusate, scab hypodermis layer tissue to have ash Yellow or the liquid outflow of taupe brown stench wound, pruitus, whole skin surface be greasy etc., and symptom has significant curative effect.
2nd, suffer from allergic dermatitis, bite dermatitis, solarized dermatitis, the pork pig of pig necrodermatitis to use in the present invention Medicine preparation can fully recover for 3-5 days, cure up to more than 95%, pork pig is had no toxic side effect, easy to use.
3rd, the direct dipping of the medicine in pig skin injury tissue and absorb, pass through local action and absorb after whole body adjust Effect, improves local blood circulation, slows down skin itching symptom, promotes the regeneration of skin tissue cell, accelerates wound healing, has It can effectively prevent infection from suppurating.
4. the Chinese medicine preparation of present invention preventing and treating pork pig dermatitis, uses natural plants for raw material, medicine source is extensive, financial cost It is low, good therapeutic effect is played to pork pig dermatitis, and remained without antimicrobial and antibiotic-free, meet aquaculture natural nuisance-free Development characteristic.
5. pork pig suffers from after dermatitis, papule not of uniform size or punctation, its play triggered typically can all occur Itch, cause pork pig constantly to dawdle, bite, mood is manic, it is not easy to be quiet, ultimately result in coating difficult.The wine of the present invention Smart spray, spray is easy, easy to use, carries more convenient.
Embodiment
Embodiment 1
By dry clean fresh 5 parts of kuh-seng, 5 parts of the Radix Astragali, 20 parts of baeckea frutescen, 15 parts of margosa, 15 parts of Chinese wampee leaf, folium artemisiae argyi 20 parts are broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, it is 6-8 times of medicine gross weight to add water, is burnt Open 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, clear liquid, the sick pig medicine for suffering from allergic dermatitis by 3 Bathe in obtained clear liquid, while dipping the superficial skin that clear liquid acts on this 3 sick pigs with brush, twice daily.After 5 days this 3 The rotten to the corn wound repair of epidermis of head sick pig, pig is not dawdled, without faint yellow diffusate.
Embodiment 2
By dry clean fresh 7 parts of kuh-seng, 7 parts of the Radix Astragali, 25 parts of baeckea frutescen, 17 parts of margosa, 17 parts of Chinese wampee leaf, folium artemisiae argyi 25 parts are broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, it is 7-9 times of medicine gross weight to add water, is burnt Open 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, clear liquid, the sick pig medicine for suffering from bite dermatitis by 4 Bathe in obtained clear liquid, while dipping the superficial skin that clear liquid acts on this 4 sick pigs with brush, twice daily.After 4 days this 4 The red edemous papule at the positions that bear a pretty, delicate skin such as head sick pig auricle, eyelid, belly disappears, and sick pig acts without wiping is rubbed.
Embodiment 3
By dry clean fresh 8 parts of kuh-seng, 8 parts of the Radix Astragali, 27 parts of baeckea frutescen, 18 parts of margosa, 18 parts of Chinese wampee leaf, folium artemisiae argyi 27 Part is broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, addition water is 6-10 times of medicine gross weight, boiled 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, clear liquid, the sick pig dipping for suffering from necrodermatitis by 5 In obtained clear liquid, while dipping the superficial skin that clear liquid acts on this 5 sick pigs with brush, twice daily.This 5 after 5 days Sick pig is disappeared without the big red papules of the grain of rice by the tubercle of the dry scab of papule developing deeply, without hard swelling symptom, scab hypodermal layer group admittedly Knit reparation, no lark or the wound liquid outflow of taupe brown stench.
Embodiment 4
By dry clean fresh 10 parts of kuh-seng, 10 parts of the Radix Astragali, 30 parts of baeckea frutescen, 20 parts of margosa, 20 parts of Chinese wampee leaf, folium artemisiae argyi 30 parts are broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, it is 7-8 times of medicine gross weight to add water, is burnt Open 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, clear liquid, the sick pig medicine for suffering from exudative dermatitis by 6 Bathe in obtained clear liquid, while dipping the superficial skin that clear liquid acts on this 6 sick pigs with brush, twice daily.After 5 days this 6 Head sick pig encloses near the eyes, nose, lip, skin redfree spot after gum and ear, and whole skin surface is without oil sample material.
Embodiment 5
By dry clean fresh 6 parts of kuh-seng, 6 parts of the Radix Astragali, 23 parts of baeckea frutescen, 16 parts of margosa, 16 parts of Chinese wampee leaf, folium artemisiae argyi 23 parts are broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, it is 3-4 times of medicine gross weight to add water, is burnt Open 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, according to weight 1:1 ratio, volume is added by clear liquid Concentration 50-90% alcohol, mixing, which is fitted into spray bottle, obtains alcohol spray, is sprayed at 7 diseases with allergic dermatitis With pig, three times a day.The rotten to the corn wound repair of the epidermis of this 7 sick pigs after 4 days, without faint yellow diffusate, pig is not dawdled.
Embodiment 6
By dry clean fresh 9 parts of kuh-seng, 9 parts of the Radix Astragali, 29 parts of baeckea frutescen, 19 parts of margosa, 19 parts of Chinese wampee leaf, folium artemisiae argyi 28 Part is broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, addition water is 4-5 times of medicine gross weight, boiled 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, according to weight 1:1 ratio, adds volume dense by clear liquid 50-90% alcohol is spent, mixing, which is fitted into spray bottle, obtains alcohol spray, is sprayed at 8 sick pigs with bite dermatitis With, three times a day.The red edemous papule at the position that bears a pretty, delicate skin such as this 8 sick pig auricles, eyelid, bellies disappears after 3 days Lose, sick pig acts without wiping is rubbed.
Comparative example 1
Take the sick pig of 3 symptoms similarly to Example 1 applied after its affected part is cleaned up put on the skin by 500 milliliters of kerosene, 10 grams The embrocation medicine that camphor ball, 20 grams of carbolic acids and 20 grams of creosotes are made, three times a day.Still there be the epidermis of this 3 sick pigs after 7 days A small amount of erosion surface of a wound, pig is still dawdled action, still there is a small amount of faint yellow diffusate.
Comparative example 2
The sick pig of 4 symptoms similarly to Example 2 is taken to coat zinc ointment in its superficial skin and embrocate 3% crystal violet alcohol Liquid, three times a day;The position that bears a pretty, delicate skin such as the auricle of this 4 sick pigs, eyelid, belly still has a small amount of red edemous after 7 days Papule, sick pig often occurs rubbing wiping action.
Comparative example 3
The sick pig intramuscular injection occrycetin parenteral solution of 5 symptoms similarly to Example 3 is taken, once a day;This 5 after 4 days Sick pig is disappeared without the big red papules of the grain of rice by the tubercle of the dry scab of papule developing deeply, without hard swelling symptom, scab hypodermal layer group admittedly Knit reparation, no lark or the wound liquid outflow of taupe brown stench.
Comparative example 4
The sick pig Amoxicillin of 6 symptoms similarly to Example 4 is taken, terramycin or TMP synergistic sulfonamides spice give its food With three times a day;This 6 sick pigs enclose near the eyes after 4 days, nose, lip, skin redfree spot after gum and ear, but whole skin Surface still suffers from a small amount of oil sample material.
Comparative example 5
Take fortimicin, reinforcing that the sick pig of 7 symptoms similarly to Example 5 produces with the animal husbandry of the Shandong sky(Pest poison health Or qingwen baidu powder)Whole body is sprayed after drinking-water, compound aldehyde sterilization dilution agent, three times a day.The epidermis base of this 7 sick pigs after 4 days This is without the rotten to the corn surface of a wound, and pig is without action of dawdling, without faint yellow diffusate.
Comparative example 6
The sick pig of 8 symptoms similarly to Example 6 is taken to imitate ointment in its superficial skin coating celo and embrocate 3% crystal violet Alcohol liquid, three times a day;Still there is a small amount of red water at the position that bears a pretty, delicate skin such as the auricle of this 8 sick pigs, eyelid, belly after 7 days Swollen property papule, sick pig often occurs rubbing wiping action.
In 6 described " embodiments ", Chinese medicine preparation produced by the present invention has good treatment to preventing and treating pork pig dermatitis Effect, can effectively treat pork pig allergic dermatitis, bite dermatitis, exudative dermatitis, necrodermatitis.Preceding 4 uses External application aqua, i.e., daily give with above-mentioned illness pig dipping in the present invention external application aqua twice, while being dipped with brush The superficial skin that above-mentioned external application aqua acts on above-mentioned sick pig twice, is used in conjunction 3~5 days;Two use alcohol preparation afterwards, The alcohol preparation with allergic dermatitis, the sick pig sprinkling present invention of bite dermatitis is given, three times a day, is used in conjunction 3~4 days. Both preparations can allow the pork pig with allergic dermatitis, bite dermatitis, exudative dermatitis, necrodermatitis to be fully recovered, and And have no toxic side effect.And in 6 described " comparative examples ", " comparative example 1 ", " comparative example 2 " and " contrast implementation Example 6 " uses ointments preparation, and such drug matrices are difficult to be absorbed by tissue, and healing time is long, DeGrain.It is " right Than embodiment 3 ", " comparative example 4 " and " comparative example 5 " uses antibiotic agents and antimicrobial class, and medicine is shown in Effect is fast, but the side effect produced is very big.Although the drug matrices of antibioticses are easily absorbed by sick pig, effect is notable, super agent Amount, prolonged abuse of antibiotics, not only cause the waste of medicine, increase cost payout;Can also trigger when serious toxic reaction, Allergic reaction and suprainfection even cause pig dead.Long-term taking antimicrobial class, pig has reformed into a bacterium selection training Foster carrier, those germs for having escaped antibiotic can become the strength pathogenic bacteria with medicine resistance ability, even usually very general Logical bacterium can also make a variation as super pathogenic bacteria.Once there is the chance for traveling to people, human body can not be low-grade.Another is asked Topic, antimicrobial can be also remained in pork, after people has eaten, just into indirect victim.
By above-mentioned contrast, the pork pig for suffering from dermatitis is entered compared to using ointments preparation, antibioticses and antimicrobial class Row treatment, the Chinese medicine preparation of present invention preventing and treating pork pig dermatitis, uses natural plants for raw material, and extensively, financial cost is low, energy for medicine source Enough effectively preventing effect, enhancing are played for pork pig allergic dermatitis, bite dermatitis, exudative dermatitis, necrodermatitis The immunity of pig;Chinese medicine preparation prepared by the present invention both played good therapeutic effect to pigskin inflammation, there is noresidue, nontoxic pair again The characteristics of effect, meet the development characteristic of aquaculture natural nuisance-free.

Claims (2)

1. a kind of traditional Chinese medicine for outer use for preventing and treating pork pig dermatitis, is made up of the raw material of following parts by weight:5-10 parts of kuh-seng, the Radix Astragali 5-10 parts, 20-30 parts of baeckea frutescen, 15-20 parts of margosa, 15-20 parts of Chinese wampee leaf, 20-30 parts of folium artemisiae argyi;
The traditional Chinese medicine for outer use of described preventing and treating pork pig dermatitis is external application aqua or alcohol spray;
The production method of the external application aqua is by weight by dry kuh-seng, the Radix Astragali, baeckea frutescen, margosa, Chinese wampee leaf, Chinese mugwort Leaf is broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, addition water is 6-10 times of medicine gross weight, boiled 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, clear liquid added appropriate preservative bottling, obtains product;
The production method of the alcohol spray is by weight by dry kuh-seng, the Radix Astragali, baeckea frutescen, margosa, Chinese wampee leaf, Chinese mugwort Leaf is broken into 100 targeted fine powders;Medicinal powder is poured into pot and soaked 30 minutes, addition water is 3-5 times of medicine gross weight, boiled 5-30 minutes, when fluid temperature is down to 30 DEG C -60 DEG C, filtering, according to weight 1:1 ratio, adds volume dense by clear liquid 50-90% alcohol is spent, mixing, which is fitted into spray bottle, obtains product.
2. application of the traditional Chinese medicine for outer use in treatment pork pig dermatitis medicine is prepared described in claim 1, including preventing and treating pork pig Allergic dermatitis, bite dermatitis, the application of exudative dermatitis and necrodermatitis.
CN201410769528.5A 2014-12-15 2014-12-15 Prevent and treat the Chinese medicine preparation of pork pig dermatitis Expired - Fee Related CN104510815B (en)

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