CN103860977B - A kind of pharmaceutical composition for the treatment of dermatitis - Google Patents

A kind of pharmaceutical composition for the treatment of dermatitis Download PDF

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CN103860977B
CN103860977B CN201410110569.3A CN201410110569A CN103860977B CN 103860977 B CN103860977 B CN 103860977B CN 201410110569 A CN201410110569 A CN 201410110569A CN 103860977 B CN103860977 B CN 103860977B
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dermatitis
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pharmaceutical composition
treatment
medicine
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黄文超
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Huang Jinling
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Abstract

The invention discloses a kind of pharmaceutical composition for the treatment of dermatitis, made by the raw material of following weight parts respectively: tribulus terrestris 12-28 part, fruit of summer cypress 12-28 part, hairy euphorbia 12-28 part, kuh-seng 6-14 part, smilax 6-14 part, favus skin 6-14 part, seed of cowherb 6-14 part, root bark of tree peony 6-14 part, Damnacamthus indicus 6-14 part. In clinical use, successful.

Description

A kind of pharmaceutical composition for the treatment of dermatitis
Technical field
The present invention relates to technical field of traditional Chinese medicines, be specifically related to be prepared from taking Chinese herbal medicine as raw materialThe pharmaceutical composition for the treatment of dermatitis.
Background technology
Dermatitis is clinical comparatively common disease, organizes the dermatitis of recommendation to divide according to world's allergiaClass mode, dermatitis is divided into eczema, contact dermatitis, other types dermatitis. Dermatitis and eczema Chang ZuoweiSynonym is used to refer to a kind of scytitis, represents that skin is for chemicals, albumen, bacterium and fungiEtc. the allergic reaction of all materials. Eczema one word do not have special implication, and dermatitis has restrictionMeaning. If as diagnosis term, refer to corium, epidermis association response by dermatitis replacement eczema,It can be acute, subacute and chronic, and this three can combine existence. Bad life habits. AsConventional overheated water face-washing, or overfrequency ground uses the skin cleaners such as perfumed soap, mildy wash, do not note at ordinary timesMeaning is to ultraviolet protection etc., and these physicochemical irritations all can change or protective barrier and the blood of injured skinPipe regulatory function.
For dermatitis in treatment medicine, mostly what doctor trained in Western medicine mainly adopted is corticoid medicine at present, for oral administrationAntihistamine and antibiotics. But in recent years, due to the skin lesion of external application hormone preparation initiationSharply increase, bad reaction is remarkable, becomes the social concern that people show great attention to. Long-term external application hormoneCan cause osteoporosis, hypoimmunity, fungal infection, atrophoderma, pigmentation, blood capillaryEnlargement of pipe, burn feeling, vergeture, crinosity, seat sore and brandy nose sample fash. Hormone is to a variety of causesThe scytitis that (as infection, allergy, physical agent etc.) cause has obvious non-specific inhibition to doWith, though can make the state of an illness improve rapidly after external application, it is short-term relief of symptoms, inflammation-inhibiting reaction,Instead of healing inflammation, can not fundamentally treat the cause of disease. The abuse of hormone, also can cause hormone to be complied withDrug withdrawal rely dermatitis to occur, once will recur or worsen. When after external application hormone again, above-mentioned symptomOr sign disappears very soon, drug withdrawal once again, sends out rapidly again, and more violent than last time, general medicineBe difficult to control. The antibiotic application of Western medicine is the primary treatment means of dept. of dermatology, but the mistake of applyingThe phenomenon of abusing in journey grows in intensity, and this has not only caused the serious waste of medicine, also increases bacterium resistance toThe generation of the property of medicine, has caused huge harm to society.
What Chinese traditional treatment dermatitis mainly adopted is oral decoction, and the combination therapy of external-use lotion, although keep awayExempt from the pathology that the Irrational Use of Drugs of various doctors trained in Western medicine causes, pharmacological dependence etc., but curative effect is how, depositsIn larger difference, and formulation is single. Thus, avoid simultaneously Western medicine use in the pathology that may causeAnd pharmacological dependence, can avoid again the unconspicuous medicine of Chinese Herbs to need development badly.
Summary of the invention
The technical problem to be solved in the present invention is to pay no attention to for treating dermatitis effect of drugs in prior artThink or the deficiency such as slow that takes effect, a kind of pharmaceutical composition of effective treatment dermatitis is provided.
In pharmaceutical composition of the present invention, the consumption of each component is that inventor draws through a large amount of practice summaries, this pharmaceutical composition is made up of the raw material of following weight parts:
Tribulus terrestris 12-28 part, fruit of summer cypress 12-28 part, hairy euphorbia 12-28 part, kuh-seng 6-14 part,Smilax 6-14 part, favus skin 6-14 part, seed of cowherb 6-14 part, root bark of tree peony 6-14 part, Damnacamthus indicus6-14 part.
Be preferably:
Tribulus terrestris 16-24 part, fruit of summer cypress 16-24 part, hairy euphorbia 16-24 part, kuh-seng 8-12 part,Smilax 8-12 part, favus skin 8-12 part, seed of cowherb 8-12 part, root bark of tree peony 8-12 part, Damnacamthus indicus8-12 part.
Optimum is:
20 parts of tribulus terrestris, 20 parts of the fruit of summer cypress, 20 parts of hairy euphorbias, 10 parts of kuh-sengs, smilax 10Part, 10 parts of favus skins, 10 parts of the seeds of cowherb, 10 parts of the root barks of tree peony, 10 parts of Damnacamthus indicus.
The formulation of medicine of the present invention can be the doctors such as granule, tablet, powder, paste, vinaAcceptable formulation on, their preparation method, supplementary product consumption are undertaken by existing common process.
The present invention also comprises the application of aforementioned pharmaceutical compositions in the medicine of preparation treatment dermatitis.
In pharmaceutical composition prescription of the present invention:
Tribulus terrestris, another name thatch, puncture vine, Fructus Tribuli, bypass, bend people, only row, jackal plumage, liter push away,Be lamb's-quarters, tribulus terrestris, society puncture vine, native puncture vine, tribulus terrestris, drought grass, triangle puncture vine, triangle sting,Anistree thorn, puncture frame, wild water caltrop, water chestnut, firmly puncture multitude, puncture multitude Follicle radish, puncture vine dog, Qi Lidan,Tuo Luoci, water caltrop thorn, English name PuncturevineCaltropFruit Latin plant animal ore depositName 1.TribulusterrestrisL.2.TuibuluscistoidesL. Gui Jing: liver;Lung; Kidney; The heart channel of Hang-Shaoyin. Chemical composition of Chinese materia medica: fruit is silver-colored linden containing tribulus terrestris glucoside (tribuloside)Glucoside (tiliroside), Kaempferol (kaempferol), Kaempferol-glycoside(kaemopferol-3-glucoside), Kaempferol-rutinoside(kaempferol-3-rutinoside), Quercetin (quercetin), vitamin C, also containsDiosgenin (diosgenin). Seed contains trace harman arabine (harman), in seed oilMain fatty acid has palmitic acid (palmiticacid), stearic acid (stearicacid), oilAcid (oleicacid), linoleic acid (linoleicacid) and leukotrienes (linolenicacid)Deng. Pharmacological action: the 1. effect of pair cardiovascular system: the thick saponin preparation Tribusponin of puncture vine cauline leafCan strengthen the cardiac contractile force of cat and rabbit, reducing heart rate, coronary artery dilator and peripheral vascular, and aobviousShow the hypotensive effect of mitigation. Tribuloside still has obvious anti-heart ischemia effect. 2. pair smooth muscleEffect: the effect that water Extraction parts has pair anti-acetylcholine to shrink to rat degree body intestinal tube, alkaloid portionPoint also can resist isolated rat intestinal tube and frog rectus aabdominis because of the caused contraction of acetylcholine. 3. profitUrine effect: alkaloid part has the diuresis of mitigation. 4. anti arteriosclerosis and anti-platelet aggregation are doneWith: the Tribusponin of the oral l0ml/kg dosage of rabbit, continuous 60 days, can significantly reduce experimentThe cholesterol levels of property blood high-cholesterol disease, rising lecithin cholesterol ratio. Prevention experiment can be remarkableHinder cholesterolemia processed and increase, and can suppress the decline of lecithin cholesterol ratio, in addition, also there is preventionArtery, the lipid deposition of cardiac muscle and liver. 5. strong and delaying senility function: puncture vine cauline leaf is thickSaponin is stimulated by high temperature, low temperature, anoxic and Suppressor cells to mouse all have obvious protective effect: alsoCan significantly reduce vitamin C (Vc) content in adult rat adrenal tissue, also can suppress heavy dose of hydrogenation canThe exhaustion phenomenon that pine causes occurs, and the Vc content that ACTH is caused declines and shields. Excise littleAfter mouse bilateral adrenal glands, its resisting oxygen lack no longer reappears. These effects may have with adrenal cortexClose, regulating its function to exempt from exhaustion may be to realize one of strong approach. 6. the strong effect of property:The preparation that Tribesta(puncture vine aerial part is made) giving that male rat is oral can obvious stimulation spermForm, excited Sai Tuoli cell (Sertolicell) activity, increases sexual desire; Give female ratsCan promote to oestrus, improve fecundity.
The fruit of summer cypress, another name: ground certain herbaceous plants with big flowers (" herbal classic "), ground wheat (" not record "), beneficial bright (" property of medicine opinion "),Broom (" Japan hanako materia medica ") that falls, bamboo broom (" the southern regions of the Yunnan Province book on Chinese herbal medicine "), thousand chieftains (" Wanbing Huichun, Curative Measures for All Diseases "),Broom vegetable seeds (" Xinjiang medicinal material "), iron sweep bundle (" Traditional Chinese Medicine in Sichuan will "), for chenopod summer cypressFruit. Composition: seed is containing triterpenoid saponin, oil 15%. Green portion is containing alkaloid. Function cures mainly:Diuresis, clearing away damp-heat. Control difficult urination, gonorrhoea, under band, hernia, rubella, sore, mange,Private parts is wet itches. 1. " herbal classic ": " main bladder heat, diuresis. Bowl spares, beneficial vital essence. " 2. " not Lu ":" hot gas in peeling skin, the loose sore of disliking, hernia lump in the abdomen, reinforcing yin essence, makes people moist. " 3. " property of medicine opinion ": " withActinolite is with clothes, and main husband's impotence does not rise, tonifying Qi benefit power; Control cloudy ovum Huang disease, the wind that reduces phlegm and internal heat, can make soupTake a shower. " 4. " Japan hanako materia medica ": " control visitor's heat red swollen. " 5. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " sharp bladder urineAccumulated heat, washes the wind of skin, treats married woman all through visitor's heat, and clear sharp tire heat, under humid tropics. " 6. " book on Chinese herbal medicineOriginal ": " accumulated heat in peeling skin, except skin exogenous damp is itched. " 7. essentials of Matea Medica: " beneficial smart reinforcing yin essence,Except abnormal heat, diuresis and treating stranguria. "
8. " beautiful Chinese catalpa medicine solution ": " treat the head and swell and ache, fox hernia the moon is ruined, Low Back Pain hypochondriac pain, and bloody flux, dislikes sore. "
Hairy euphorbia, another name: fly upward greatly, large milk grass, sessile alternanthera herb, newborn seed grass, fly grass mutually, for greatlyThe whole herb with root of halberd section plant hairy euphorbia. Nature and flavor: pungent; Sour and astringent, cool; Mild toxicity. Effect: heat-clearing solutionMalicious, inducing diuresis and reducing edema. Effect classification: heat-clearing and detoxifying drug. Cure mainly: puerperal lactation deficiency, lung carbuncle, acute mastitis,Dysentery, have loose bowels, hot pouring, blood urine, eczema, the ringworm of the foot, pruitus, furuncle swelling toxin, noma.
Kuh-seng, another name matrine (" detailed outline "), chuanshentong (" Guizhou side's medicine among the people collection "), phoenix claw is (" wideWestern Chinese veterinarian's medicine is planted "), ox ginseng (" Hunan medicine will "). For the root of beans Plants kuh-seng. Composition:Root contains multiple alkaloid: d-Matrine, d-Oxymatrine, sophoranl l-Anagyrine, l-methyl goldSparrow flower alkali, l-baptifoline and sophocarpine. Also containing flavonoids: Xanthohumol, isoxanthohumol, 3,4 ',5-tri-hydroxyls-7-methoxy-8-isoamylene radical chromocor, 8-prenylkaempferol etc. Stem, leaf are containing resedaElement-7-glycoside. Function cures mainly: heat-clearing, eliminating dampness, desinsection. Control toxic-heat and blood stasis, discharging fresh blood stool,Jaundice, leukorrhea with reddish discharge, infantile pneumonia, infantile malnutrition due to digestive disturbances or intestinalparasites, acute tonsillitis, anal fistula, prolapse of the anus, skin scabiesItch, scabies leprosy is disliked sore, and the erosion of vulva is wet itches, and scrofula, scalds. Control trichomonas vaginitis outward.
Smilax, another name: aetite, white surplus grain, careless aetite, thorn umbellate pore furgus, siphon, hard meal,RHIZOMA SMILACIS GLABRAE, kadsurae coccineae, mountain pig manure, mountain region chestnut, cross that ridge is outstanding, mountain ox, cold meal head, mountain are come back, for a long timeOld potato, hair tail potato, Hu Ling, the old potato of dog, scarlet kadsura root, hard meal head potato, native Siberian cocklebur, mountain lose grain, dogBright head, point shaven head, mountain firmly, very good, white chinaroot greenbrier, connect meal, RHIZOMA SMILACIS GLABRAE, be liliaceous plant light leafThe dry rhizome of chinaroot greenbrier SmilaxglabraRoxb.. Composition: rhizome is containing saponin, tannin, resin etc.The root of congener Smilaxpseudo-china contains alkaloid, volatile oil, hexose, tannin, plantsThing sterol and linoleic acid, oleic acid etc. Rhizome is containing smilax saponin class (smilaxsaponins), Qi ZhongyiPlant and be known as diosgenin (diosgenin) and 1 molecule glucose, 2 molecule rhamnoses compositions; SoapStill there is tigogenin in glucoside unit. Another containing Astilbin, Isoengelitin, butanedioic acid, Daucosterol, palm fibrePalmitic acid acid, cupreol, and alkaloid, volatile oil, sugar, tannin, resin, sterol, starchDeng. Function cures mainly: dehumidifying, and removing toxic substances, easing joint movement. For damp and hot stranguria with turbid discharge, under band, carbuncle is swollen, scrofulaScrofula, mange, the limbs contraction due to syphilis and mercury poisoning, arthralgia and myalgia.
Favus skin, formal name used at school cotexdictamni, is rutaceae shaggy-fruited dittany DictamnusDasycarpusTurcz. dry root skin. Chemical composition: root is containing tinea alba alkali, dictamnolactone, paddySterol, obacunonic acid, trigonelline, choline, Ash skin ketone. Still containing campesterol, skimmianine, γ-Fagarine, dasycarpamin. Aerial part contains psoralen and xanthotoxin. Nature and flavor: bitter salty,Cold. 1. " herbal classic ": bitter, cold. 2. not " not Lu ": salty, nontoxic. 3. " book on Chinese herbal medicine is stated ": bitter micro-Salty micro-pungent. Gui Jing: enter spleen, stomach warp. 1. " detailed outline ": enter lunar, the Yangming Channel of foot, double staff tooYin, yang is bright. 2. " book on Chinese herbal medicine is original ": enter lung, small intestinl channel. 3. " new compilation of materia medica ": enter spleen, stomach,Double enter bladder, small intestine. Function cures mainly: heat-clearing and damp-drying drug, the removing toxic substances of dispeling the wind, for damp and hot sore, yellow waterDripping, eczema, rubella, mange sore La, rheumatic fever numbness, jaundice urine is red. 1. " herbal classic ": main headWind, jaundice, coughs contraryly, drenches drop, in woman's the moon, swells and ache, and the dead flesh of arthritis with fixed pain caused by dampness, is unable to flex and stretch the extremities, start-stop, OKStep. 2. " not Lu ": treat four limbs uneasiness, time too hot in row abdomen, drink water, want to walk, call out children'sFrightened epilepsy, married woman is bitterly remaining postpartum. 3. " property of medicine opinion ": control all hot malicious wind, dislike wind, wind sore, mangeRed rotten, eyebrow is sent out de-crisp, and musculus cutaneus is anxious, high fever aversion to cold; Principal solution heat is yellow, wine is yellow, acute febrile, paddy Huang, laborYellow etc. 4. " hand collection side, the Ministry of War in feudal China ": treat lung and cough. 5. " Japan hanako materia medica ": get round by bribery, sharp nine orifices andBlood vessels, and all wandering arthritis muscles and bones are weak weary, logical small intestine aqueous vapor, disease when sky row, headache eye pain. Root skin is good,Flower function is the same. 6. " book on Chinese herbal medicine is original ": control all scabies leprosys, dislike wind, mange, red bayberry, all sore heatPoison.
The seed of cowherb, calls milk rice, Wang Buliu, Mai Lanzi, cuts gold, SEMEN VACCARIAE. Medicinal part:For the seed of pinkwort cow-fat. Composition: seed, containing triterpenoid saponin, is called vacsedoside(vac-segoside) have A, B, C, a D4 kind, all for being spread out by gypsogenin (gypsogenin)Raw polysaccharid glucoside. The structure of vacsedoside B and C is definite, and the sugar moieties of glucoside A has D-Glucuronic acid (D-glucuronicacid), D-galactolipin (D-galactose), Arabinose(L-arabinose), D-wood sugar (D-xylose), D-fucose (D-fucose), L-rhamnose(L-rhamnose), the sugar moieties of glucoside D has D-Glucose aldehydic acid, D-galactolipin, D-wood sugar, D-Fucose, L-rhamnose and D-Glucose (D-glucose). Four kinds of saponins are hydrolyzed all to obtain same kingNot staying places saponin (vaccraoside), is gypsogenin-3-β-D-Glucose aldehydic acid glucoside(gypsogenin-3-β-D-giucuronoside. Again containing glycosides displayed: seed of cowherb glycosides displayed(vaccarin), isosaponaretin (isosaponarin). Also contain phytin (phytin), phosphatide(phospholipid), stigmasterol (stigmasterol) etc. Function cures mainly: promoting circulation of blood is stimulated the menstrual flow, and expedites the emergence ofLactogenesis, detumescence sore. Control women through closing, alactation, difficult labour, blood drenches, and carbuncle is swollen, and metal-inflicted wound is hemorrhage.The lactogenesis of stimulating the menstrual flow: for through closing and agalactia. It is many and obstructed that the seed of cowherb is controlled milk; As milk lacks itAsthenic symptoms, need the medicine of adapted tonifying Qi and blood. Activating blood circulation and reducing swelling: for hemostasis lump and sore and toxic. 1." herbal classic ": " main metal-inflicted wound, hemostasis, by pain, goes out thorn, except cold in wandering arthritis. " 2. " not Lu ": " the only heartTired nosebleed epistaxis. "
The root bark of tree peony, i.e. moutan bark, is the dry root skin of ranunculaceae peony. Originate in the ground such as Anhui, Shandong.Excavate root autumn, remove radicula, strip root skin, dry. Raw using or stir-fry use. Compendium of Material Medica:" nourishing Yin and falling fire, separate spot poison, throat, diuresis stasis. Descendant specially controls fire mutually with yellow tiller, noThe merit of knowing the root bark of tree peony more wins also. Red colored person's profit, the person of spending in vain mends, and people also seldom realizes, and should distinguish it. " modern timesResearch, contained paeonol and glucosides constituents in addition thereof all have antiinflammatory action; The methyl alcohol of moutan bark is carriedGet thing and have inhibition Platelet; Paeonol has the maincenters such as calmness, cooling, antipyretic, analgesia, spasmolysisThe effects such as inhibitory action and antiatherosclerosis, diuresis, antiulcer. Meridian distribution of property and flavor: cold in nature, tasteBitter; Cool; Be slightly cold. The thoughts of returning home; Liver; Kidney; Lung channel. Bitter, pungent, is slightly cold. The thoughts of returning home, liver, kidney channel.Effect: clearing heat and cooling blood; Promoting blood circulation to remove blood stasis. Warm heat disease heat invading xuefen; Send out spot; Tell nosebleed; After pyreticosisPhase, hot Fu Yin divided heating; Deficiency of Yin osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhoea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury;Rheumatic fever numbness.
Damnacamthus indicus, another name: thorn tiger (" Bencao Tujing "), elderly person for whom a birthday celebration is being held's grass (" longevity territory god side "), Shou Tingmu(" presbyopic glasses "), sparrow does not step on, embroidery needle (" Illustrated Book on Plants "), perny false fairybells rhizome, day pin, mouseThorn (" Jiangxi traditional herbal medicine "), protruding canine teeth thorn, a thousand pieces of gold thorn, goose mouth flower root, yellow chicken orchid, thousand lancets,Leaf on pin, along tea wind, pin do not step on, the native shank coptis, Ilex pernyi, the little coptis (" Hunan medicine will "),Radix zanthoxyli, thin floricome (" Guangxi medicine is planted register "), bird does not step on (" Jiangxi herbal medicine "), snake only,Towards sky thorn, draw point wood, brave leaf, mouse rifle, tiger thorn, leaflet thorn wind, processus styloideus radii tiger thorn, red oldMouse thorn, red polygala root, Bai Fengzhu (" Zhejiang conventional herbal medicine among the people "), complete for madder wort Damnacamthus indicusGrass or root. Composition: the root of large shape Damnacamthus indicus is containing multiple anthraquinone component damnacanthal, damnacanthol, Damnacamthus indicus Buddhist nunJuzunal, demethyl damnacanthal, Norjuzunal, benzylxanthopurpurin, madder calmly,Element-1-methyl ether, 5-hydroxyl alizarin-1-methyl ether. Function cures mainly: expelling wind and removing dampness, activating blood circulation and reducing swelling. Control painWind, arthralgia due to wind-dampness. Phlegmatic cough, lung carbuncle, oedema, lump in the abdomen, jaundice, women is through closing, children's's infantile malnutrition due to digestive disturbances or intestinalparasitesLong-pending, nettle rash, traumatic injury. 1. " Bencao Tujing ": " manage all wind diseases that swell and ache. " 2. " plantThe real figure of name examines ": " fill blood. " 3. " Zhejiang traditional herbal medicine ": " and root and flower: invigorate blood circulation, sharp joint.Control general mood. " 4. " Hangzhou medicine is planted will ": " control rheumatalgia. " 5. " Guangxi medicine is planted register ": " root: onlyCough the gas of enriching blood. Control tuberculosis, internal injury. " 6. Guangzhou army " conventional Chinese herbal medicine handbook ": " diuresis disappearsSwollen, promoting blood circulation to remove blood stasis. Treating acute and chronic hepatitis, spleen enlargement. "
From the angle of the traditional Chinese medical science, tribulus terrestris is controlled health pruritus; The fruit of summer cypress, hairy euphorbia clearing heat and promoting diuresis, dispel the windAntipruritic; Kuh-seng energy removing dampness and destroying parasites; Smilax, favus skin heat-clearing and damp-drying drug, the removing pattogenic heat from the blood and toxic material from the body of dispeling the wind; King is notStay row to control wind poison, promoting blood circulation; Damnacamthus indicus expelling wind and removing dampness, activating blood circulation and reducing swelling; Root bark of tree peony clearing heat and cooling blood; Huoxue San "The stasis of blood. All medicines share, and have clearing heat and detoxicating, the loose soft heavily fortified point of wind, Anti-Puritic and insecticidal, clearing heat and expelling damp, anti-inflammatory press downThe effect of bacterium, desensitization convergence. For chronic eczema, thickening property of cutin eczema, beriberi, athlete's foot, handAll kinds of dermatosis chronic diseases such as tinea pedis, tinea pedis and manus, psoriasis, psoriasis, tinea circinata, allergic urticaria,And various dermatitis, the red swelling of the skin traces that cause because of the allergy symptom such as itch has good effect.
Compared to existing technology, tool of the present invention has the following advantages:
1, pharmaceutical composition of the present invention, the natural crude drugs that have drawn from, because it is not containing hormone or antibiotic,Therefore can reach the effect for the treatment of both principal and secondary aspect of disease to various obstinate dermatitis, without the caused look of various sebum hormone class ointmentElement precipitation, hormone rely on, the side effect such as continuous repeatedly, started the pure natural draft of all kinds of dermatitis and treatedSide.
2, pharmaceutical composition of the present invention, applied range, for all kinds of dermatosis chronic diseases, as chronicEczema, thickening property of cutin eczema, beriberi, athlete's foot, tinea of feet and hands, tinea pedis and manus, psoriasis, copper coinTinea, rubella, allergic urticaria etc., and various dermatitis, the red swelling of the skin trace causing because of allergy itchedAll there is good effect etc. symptom, even for global problem---cutin incrassation type eczema, alsoThere is outstanding effect.
Detailed description of the invention
With embodiment, the invention will be further described below, but the present invention is not limited to these enforcementExample.
Embodiment 1:
Tribulus terrestris 120g, fruit of summer cypress 280g, hairy euphorbia 120g, kuh-seng 140g, smilax 60g,Favus skin 140g, seed of cowherb 60g, root bark of tree peony 140g, Damnacamthus indicus 60g.
Take above each raw material by proportional quantity, boiling twice, adds 7 times of water gagings for the first time, decocts1.5 hours, add for the second time 8 times of water gagings, decoct 1.5 hours, collecting decoction, filters, and filtrate is concentratedWhile being 1.30(70 DEG C to relative density, survey) medicinal extract, add the dolomol auxiliary material of conventional amount used,Technique is made tablet routinely, specification 0.5g/ sheet.
Embodiment 2:
Tribulus terrestris 280g, fruit of summer cypress 120g, hairy euphorbia 280g, kuh-seng 60g, smilax 140g,Favus skin 60g, seed of cowherb 140g, root bark of tree peony 60g, Damnacamthus indicus 140g.
Take above each raw material by proportional quantity, boiling twice, adds 7 times of water gagings for the first time, decocts1.5 hours, add for the second time 8 times of water gagings, decoct 1.5 hours, collecting decoction, filters, and filtrate is concentratedWhile being 1.30(70 DEG C to relative density survey) medicinal extract, add appropriate cane sugar powder, routinely techniqueGranulation agent.
Embodiment 3:
Tribulus terrestris 160g, fruit of summer cypress 240g, hairy euphorbia 160g, kuh-seng 120g, smilax 80g,Favus skin 120g, seed of cowherb 80g, root bark of tree peony 120g, Damnacamthus indicus 80g.
Take above each raw material, clean and dry, co-grinding is crossed 80 mesh sieves, obtains powder after sterilizing.
Embodiment 4:
Tribulus terrestris 240g, fruit of summer cypress 160g, hairy euphorbia 240g, kuh-seng 80g, smilax 120g,Favus skin 80g, seed of cowherb 120g, root bark of tree peony 80g, Damnacamthus indicus 120g.
Take above each raw material by proportional quantity, boiling twice, adds 7 times of water gagings for the first time, decocts1.5 hours, add for the second time 8 times of water gagings, decoct 1.5 hours, collecting decoction, filters, and filtrate is concentratedWhile being 1.30(70 DEG C to relative density, survey) medicinal extract, add the beeswax of conventional amount used, be mixed into cream.
Embodiment 5:
Tribulus terrestris 200g, fruit of summer cypress 200g, hairy euphorbia 200g, kuh-seng 100g, smilax 100g,Favus skin 100g, seed of cowherb 100g, root bark of tree peony 100g, Damnacamthus indicus 100g.
Take above each raw material by proportional quantity, drying rear chopping, pours the raw material of chopping in cylinder into, uses45-50 degree pure mellow wine soaks, and steeps powder, and sealing, soaks 60, crosses after the elimination dregs of a decoction, fills withFill to obtain vina.
Clinical effectiveness
In order to verify its effect, 2008-2014, the product that embodiment 5 is obtained is at local hospital220 routine patients have been carried out to clinical verification, and result is as follows:
1, physical data
220 routine patients are all outpatient. Wherein male 102 examples, female's 118 examples; The oldest 72Year, minimum 12 years old; Comprise chronic eczema, thickening property of cutin eczema, beriberi, athlete's foot, brothersTinea, tinea pedis and manus, psoriasis, tinea circinata, rubella, allergic urticaria, cutin incrassation type eczema,And various dermatitis, the red swelling of the skin traces that cause because of the allergy patient with sympotoms such as itch.
2, methods for the treatment of
The product that uses the embodiment of the present invention 5, every day 3 times, is used in conjunction 15 days, if less than 15 daysRecovery from illness is stopped using.
3, criterion of therapeutical effect
Recovery from illness: dermatitis disappears completely, without scar, pigment deposition.
Effective: dermatitis disappears substantially, there are part scar, pigment deposition.
Invalid: with use before compare, basic do not change.
4, treatment results
Conclusion: the vina of the embodiment of the present invention 5 is for the skin at all ages and classes stage and different human body positionScorching treatment, recovery from illness in general 2-4 days, scar disappears, non-pigment deposition, situation severe patient, 7 daysSuccessful afterwards.

Claims (4)

1. treat a pharmaceutical composition for dermatitis, it is characterized in that it is respectively by following weight partsRaw material is made:
Tribulus terrestris 12-28 part, fruit of summer cypress 12-28 part, hairy euphorbia 12-28 part, kuh-seng 6-14 part,Smilax 6-14 part, favus skin 6-14 part, seed of cowherb 6-14 part, root bark of tree peony 6-14 part, Damnacamthus indicus6-14 part.
2. a kind of pharmaceutical composition for the treatment of dermatitis according to claim 1, is characterized in that:The weight portion of each raw material is:
Tribulus terrestris 16-24 part, fruit of summer cypress 16-24 part, hairy euphorbia 16-24 part, kuh-seng 8-12 part,Smilax 8-12 part, favus skin 8-12 part, seed of cowherb 8-12 part, root bark of tree peony 8-12 part, Damnacamthus indicus8-12 part.
3. a kind of pharmaceutical composition for the treatment of dermatitis according to claim 2, is characterized in that:The weight portion of each raw material is:
20 parts of tribulus terrestris, 20 parts of the fruit of summer cypress, 20 parts of hairy euphorbias, 10 parts of kuh-sengs, smilax 10Part, 10 parts of favus skins, 10 parts of the seeds of cowherb, 10 parts of the root barks of tree peony, 10 parts of Damnacamthus indicus.
4. in claim 1-3, the pharmaceutical composition described in any one is being prepared the medicine for the treatment of dermatitisIn application.
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