CN100574778C - Acne treating compound Chinese medicine preparation - Google Patents

Acne treating compound Chinese medicine preparation Download PDF

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CN100574778C
CN100574778C CN 200710054098 CN200710054098A CN100574778C CN 100574778 C CN100574778 C CN 100574778C CN 200710054098 CN200710054098 CN 200710054098 CN 200710054098 A CN200710054098 A CN 200710054098A CN 100574778 C CN100574778 C CN 100574778C
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许炎军
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许炎军
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Abstract

The acne treating compound Chinese medicine preparation is prepared with ginseng, pearl powder, honeysuckle, dahurian angelica root, almond and other eight kinds of Chinese medicinal materials. The preparation process includes washing the medicine materials, crushing, decocting, filtering, centrifuging to obtain supernatant, concentrating, adding pearl powder, menthol, far infrared nanometer ceramic powder, etc, high temperature sterilizing, adding glycerin and ethanol. It has functions of resisting bacteria, relieving itch, reducing oil secretion, etc. and thus obvious acne treating effect and no side effect.

Description

治疗痤疮的中药复方制剂 Traditional Chinese medicine to treat acne

技术领域 FIELD

本发明属于中药制剂技术领域,涉及一种治疗痤疮的中药复方制剂。 The present invention belongs to the technical field of Chinese medicine, it relates to a compound of traditional Chinese medicine of treating acne. 背景技术 Background technique

面部痤疮是青春期最常见的毛囊皮脂腺的慢性炎症皮肤病,又称"粉刺", 对粉刺形成的机理众说纷纭,至今尚不完全清楚,但与人体内分泌失调和外部感染有关。 Facial acne is the most common chronic inflammation of the sebaceous hair follicles adolescent skin disease, also known as "acne", the mechanism of the formation of acne have different opinions, still not entirely clear, but with the human endocrine disorders and external infections. 中医认为,粉刺系内火炽盛、郁滞肌肤所致;西医则认为青春期粉刺因雄性激素所发,皮脂腺发育旺盛,分泌增多,导致皮脂瘀积于内而形成皮脂栓塞一粉刺。 Chinese medicine believes that, within the Department of fire flaming acne, skin caused by stagnation; Western medicine believes that adolescent acne because of the male hormone hair, sebaceous glands strong, secretion, resulting in stasis of sebum to form a plug of sebum acne. 粉刺一般无炎症,但毛囊内有粉刺杆菌(Corynebactoriumacne) 生长时,便可产生溶酯酶,使聚集在粉剌内的皮脂分解出游离脂肪酸,刺激毛囊表皮产生炎症反应,使面部或胸部出现一颗颗红色的炎性丘疹。 Generally no inflammatory acne, but comedones hair follicle coli (Corynebactoriumacne) is grown, can produce soluble esterase, the aggregated powder in the punching exploded sebum free fatty acids, follicle stimulating epidermal inflammatory reaction, the face or the chest Occurrence Brilliant red inflammatory papules. 常见的寻常粉刺(Acne Vulgaris)有黑头粉刺、脓胞粉刺、暗疮和米粒样囊肿,在粉刺初发阶段,若医疗或处置不当,常会引起交互感染而形成炎状侵润,以至逐渐硬化而留下瘢痕或色素沉着,个别严重的还使皮肤易发生癌变。 Common ordinary acne (Acne Vulgaris) have blackheads, pustular acne, acne and rice cyst in acne primary stage, if medical or disposed of improperly, often cause cross contamination and the formation of inflammation-like invasion, as well as the gradual hardening stay under scars or pigmentation, particularly serious also prone to skin cancer. 目前国内外治疗痤疮的方法很多,如西医治疗,常用药有红霉素、氯霉素等,但这些药物易造成毒副作用和过敏反应,中药治疗,常用药物有复古珍珠暗疮片、连翘败毒丸等,但在治愈率、治疗效果方面难以到达满意程度,另外,外用的膏霜虽然可以控制炎症,但会使毛囊、腺管更加堵塞,造成恶性循环,故而疗效欠佳。 Current methods to treat acne at home and abroad a lot, such as western medicine, drugs commonly used erythromycin, chloramphenicol, but these drugs easily lead to side effects and allergic reactions, traditional Chinese medicine, commonly used acne drug vintage pearl piece, forsythia defeat poison balls, but the cure rate, the treatment effect is difficult to reach terms of satisfaction, in addition, topical creams although you can control inflammation, but will make the hair follicles, more duct blockage, resulting in a vicious cycle, and therefore undesirable effect. 发明内容 SUMMARY

本发明的目的是提供一种制备简单、治疗效果好的治疗痤疮的中药复方制剂。 Object of the present invention is to provide a simple, good therapeutic effect in the treatment of acne traditional Chinese medicine preparation.

本发明采用以下技术方案来实现上述目的: 一种治疗痤疮的屮药复方制剂,主要由以下重量份数的原料制成: The present invention employs the following technical solution to achieve the above object: one kind of compound preparation Che acne treatment drug, a material mainly made of the following parts by weight:

人参3~15 珍珠粉0.1〜5 金银花5~20 白芷3〜15 Ginseng pearl powder 3 to 15 5 to 20 Angelica honeysuckle 0.1~5 3~15

苦杏仁4.5〜25 蛇床子3〜15 金沸草4.5~15 大黄3〜3() Bitter almonds 4.5~25 Osthol 3~15 4.5 to 15 gold boiling grass rhubarb 3~3 ()

黄苳3~20 丹参9〜50 鸦胆子0.5〜25 苦参4.5〜20野菊花9〜15。 Yellow paper cutters 3-20 Salvia javanica 0.5~25 9~50 9~15 flavescens 4.5~20 chrysanthemum.

治疗痤疮的中药复方制剂优选主要由以下重量份数的原料制成: Traditional Chinese medicine treatment of acne is preferably made of a material mainly the following parts by weight:

人参5〜10 珍珠粉0.2〜2 金银花5〜15 白芷3〜10 Ginseng pearl powder 5 to 10 0.2~2 Angelica honeysuckle 5~15 3~10

苦杏仁5〜20 蛇床子3~10 金沸草5~10 大黄5〜20 Bitter almonds 5~20 Osthol 3-10 5-10 gold boiling grass rhubarb 5~20

黄荟5〜15 丹参10〜30 鸦胆子5〜25 苦参5~15 Hui Huang javanica 5~25 10~30 5~15 Salvia Sophora 5-15

野菊花10〜15。 Chrysanthemum 10 ~ 15.

治疗痤疮的中药复方制剂还包括以下重量份数的原料:新氮酮0.25〜2 玫瑰花香精0.5〜2青豆多肽1〜3远红外纳米陶瓷粉0.01〜2薄荷脑0.02〜5。 Traditional Chinese medicine to treat acne further comprising by weight parts of the starting material: New Azone 0.25~2 rose flavor beans polypeptide 0.5~2 1~3 far infrared nano ceramic powder 0.01~2 menthol 0.02~5. 治疗痤疮的中药复方制剂的制备方法,包括以下步骤-. Preparation of compound preparation for treating acne medicine, comprising the following steps -.

(1) 、取人参、金银花、白芷、苦杏仁、蛇床子、金沸草、大黄、黄芩、 丹参、鸦胆子、苦参、野菊花清洗、粉碎,加入6〜8倍重量的水煮沸,煎煮1〜3小时,取滤液; (1), ginseng, honeysuckle, angelica, bitter almond, Cnidium, gold boiling grass, rhubarb, scutellaria, Salvia miltiorrhiza, javanica, Sophora, wild chrysanthemum washing, crushing, addition of 6 ~ 8 times the weight of boiling water, frying ~ 3 hour boil, the filtrate;

(2) 、滤渣再加4〜6倍重量的水煎煮40min〜1小时,取滤液; (2), residues plus 4 ~ 6 times its weight of boiling water 40min~1 hours, the filtrate;

(3) 、合并两次滤液,精滤后离心,静置30min〜l小时,抽取上清液, 浓縮至相对密度为1.10〜1.25 (80°C); (3), two filtrates were combined, centrifuged after fine filtration, allowed to stand 30min~l hours, the supernatant was extracted, concentrated to the relative density of 1.10~1.25 (80 ° C);

(4) 、加入珍珠粉、薄荷脑、远红外纳米陶瓷粉、青豆多肽、新氮酮,调配加入玫瑰花香精,加蒸馏水制成相对密度为1.05〜1.15 (8(TC)的药液,瞬间高温灭菌; (4) adding pearl powder, menthol, far infrared nano ceramic powder, green beans polypeptide, new Azone formulation was added rose flavor, made from distilled water relative density of 1.05~1.15 (8 (TC) of liquid, instantaneous high-temperature sterilization;

(5) 、加入占药液重量40〜60%的甘油和占药液重量40〜60%的乙醇即制成中药复方制剂。 (5), 40~60 wt% drug solution was added accounting glycerol and 40~60% by weight of the chemical liquid accounts for ethanol that is made by traditional Chinese medicine.

上述中药复方制剂,根据病情或病患者的接受不同,可以是涂膜剂、凝胶剂、膜剂、搽剂、洗剂等各种临床适用剂型。 Above by traditional Chinese medicine, according to the disease or patients receiving different, it may be a balm, gels, films, liniments, lotions and the like suitable for a variety of clinical forms.

本发明的复方制剂对各种皮肤痤疮具有抗菌止痒、减少油脂分泌,抑制毛囊角化等作用,治疗效显著,治愈率高,无副作用,药物用量小,疗程短、经济节约。 Compound formulations of the invention having various antibacterial acne skin itching, reduced oil secretion, inhibition of Darier other effects, significant therapeutic effect, high cure rate, no side effects, small drug dosage, short course, economical. 复方制剂的原料中人参,适于补气,加强新陈代谢、免疫功能,增强体质;珍珠粉具有清热解毒、养颜美容、收敛生肌等多种功效;金银花味甘, 性寒,具有清热解毒、疏散风热的作用,临床上常用于治疗各种痈肿疮毒等; 白芷具有祛风热瘙痒、消肿排脓作用;苦杏仁药性苦、微温,润肠通便;蛇床子辛温散寒,苦温燥湿,性温助阳,独入肾经;金沸草苦、辛、咸,温, 归肺、大肠经,外治疔疮肿毒;生大黄泻毒热、破积滞、行瘀血,中医常用大 Ginseng feedstock compound preparation adapted qi, enhance metabolism, immune function, enhance physical fitness; pearl powder with detoxification, skincare, myogenic and other effects converges; honeysuckle sweet, cold, with detoxification, evacuation wind action of heat, commonly used in the clinical treatment of various carbuncle swollen sore like; Angelica having chills heat itching, swelling and pus effect; potency bitter almond bitter, slightly warm, laxative; Cnidium oct-cold temperature, bitter warm dampness, warm yang, alone into the kidney; gold boiling grass bitter, spicy, salty, warm, lung, large intestine, outside the rule boils swollen drugs; rhubarb diarrhea toxic heat, break stagnation, OK bleeding, Chinese medicine commonly used in large

黄治疗肺痈、鼻疮、痈肿,现代药理学研究证明,大黄对多数革兰氏阳性细菌有抗菌作用,其抗菌活性成分芦荟大黄素、大黄素及大黄酸对菌类在培养基中 Huang treatment of lung abscess, nasal sores, carbuncles, modern pharmacology studies have shown that rhubarb has antibacterial effect for most Gram-positive bacteria, the antimicrobial active ingredients of aloe emodin and Rhein of fungi in the medium

的呼吸、核酸及蛋白质的合成具有明显的抑制作用;黄芩性味苦寒,清热燥湿, 泻火解毒,可清肺胃之热,经药理学试验证实,黄芩有较广的抗菌谱,对金黄色葡萄球菌、绿脓杆菌、链球菌等均有抑制作用,对皮肤致病性真菌也冇抑制效力;丹参有活血化瘀,理气止痛之功效;鸦胆子苦寒,善治热毒血痢,外用蚀疮去疣;苦参具有清热泻火、解毒燥湿作用;野菊花清热解毒,消肿,对金黄色葡萄球菌、链球菌、绿脓杆菌、流感病毒等均有抑制作用。 Respiration, synthesis of nucleic acids and proteins significantly inhibited; skullcap taste bitter cold, dampness heat, purging fire detoxification, heat may be clear lung and stomach, demonstrated by pharmacological tests, Scutellaria have a wider antibacterial spectrum against Staphylococcus aureus, Pseudomonas aeruginosa, and Streptococcus are inhibited, skin pathogenic fungi Nuisance inhibitory potency; Salvia blood circulation, qi analgesic effect; javanica bitter cold, good governance Noxious heat dysentery, external corrosion acne to warts; Sophora clearing and purging fire, detoxification dampness effect; wild chrysanthemum detoxification, swelling, inhibited Staphylococcus aureus, Streptococcus, Pseudomonas aeruginosa, influenza virus. 上述原料经有机组合和辩证配伍,具有清热、解毒、活血、止痒的功效,从而达到治愈鄉:疮的目的。 The organic composition of the raw material and the dialectic compatibility, with heat, detoxification, blood, antipruritic effect, so as to achieve cure Township: sores purposes. 辅助原料新氮酮为高效皮渗剂,在低浓度下就有极强的透皮作用,可帮助皮肤吸收药液,对皮肤无剌激,无过敏反应,无毒;青豆多肽可除印痕, 使皮肤增白光洁,恢复弹性;远红外纳米陶瓷粉选用细度为300纳米左右,发射功率为90%的远红外纳米陶瓷粉,远红外纳米陶瓷粉可发射出对人体有益的4〜14微米长的远红外线,改善组织细胞的微循环和新陈代谢,促进皮肤健康;另外,制剂当中加有甘油、薄荷脑,甘油不易挥发,与水、乙醇任意相溶, 对皮肤有保湿、滋润和延长局部药效的作用,薄荷油具有清凉解毒、护肤的作用,它们有利于皮肤的生理功能的发挥;既有治疗作用,又有保护皮肤的作用, 比单纯应用乙醇,减少了皮肤的干燥、紧张感,刺激性小,患者易于接受,应用前景广阔。 Azone new auxiliary materials for the efficient transdermal permeation agent, at low concentrations there is a strong skin penetration enhancing effect, helps the skin to absorb the drug solution, no stimulation to skin, non-allergic, non-toxic; peas polypeptide can inter prints, Bai Guangjie increasing skin elasticity restored; nano ceramic powder chosen far infrared having a fineness of about 300 nm, 90% transmission power of the far-infrared nano ceramic powder, ceramic powder nano far-infrared emitting a 4~14 micrometer beneficial to humans long far infrared, improve microcirculation and metabolism of the tissue cells, promoting skin health; Further, the preparation of which add glycerol, menthol, glycerine less volatile, water, ethanol arbitrary compatibility, moisturizing the skin, moisturize and partially extended the role of efficacy, peppermint oil has the effect of cool detoxification, skin care, which is conducive to play a physiological function of the skin; both the therapeutic effect, but also the protection of the skin, than the simple application of ethanol, to reduce skin dryness, tension , irritation, easily accepted by patients, a bright future. 具体实施方式 Detailed ways

实施例,治疗痤疮的中药复方制剂主要分别选用下表内重量份数的原料制 Example traditional Chinese medicine, the treatment of acne were selected primarily under the table parts by weight of the starting materials

成: to make:

<table>table see original document page 5</column></row> <table><table>table see original document page 6</column></row> <table> <Table> table see original document page 5 </ column> </ row> <table> <table> table see original document page 6 </ column> </ row> <table>

治疗痤疮的中药复方制剂的制备:取人参、金银花、白正、苦杏仁、蛇床子、金沸草、大黄、黄芩、丹参、鸦胆子、苦参、野菊花清洗、粉碎,加入6 倍重量的水煮沸,煎煮1小时,取滤液,滤渣再加6倍重量的水煎煮40min 小时,取滤液,合并两次滤液,精滤后离心,静置30min,抽取上清液,浓縮至相对密度为1.20 (80°C),再加入珍珠粉、薄荷脑、远红外纳米陶瓷粉、青豆多肽、新氮酮,调配加入香精,加蒸馏水制成相对密度为1.10 (80。C)的药液,瞬间高温灭菌,再加入占药液重量20%的甘油、占药液重量30%的乙醇, 制成中药擦剂。 Preparation of compound preparation for treating acne medicine: ginseng, honeysuckle, n-white, bitter almond, Cnidium, gold boiling grass, rhubarb, scutellaria, Salvia miltiorrhiza, javanica, Sophora, wild chrysanthemum washing, crushing, addition of 6 times the weight of boiling water, boiling for 1 hour and the filtrate, together with 6 times its weight of residues of boiling water hr 40min, the filtrate, two filtrates were combined and centrifuged after fine filtration, allowed to stand for 30min, the supernatant was extracted and concentrated to a relatively a density of 1.20 (80 ° C), then add pearl powder, menthol, far infrared nano ceramic powder, green beans polypeptide, new azone, add perfume formulations, distilled water is made relative density of 1.10 (80.C) of liquid , instantaneous high temperature sterilization, the drug solution was added 20% by weight of glycerol, 30% ethanol by weight of the liquid, liniment made medicine.

痤疮临床轻重分级标准: Clinical acne severity grading criteria:

I级(轻度)主要皮损为粉刺,发于面部。 Class I (mild) mainly as acne lesions, occur in the face.

II级(中度)主要皮损为粉刺,并有一定量的丘疹和浅在性脓疱,主要发生在面部,少量发生在颈部、胸背部。 Grade II (moderate) lesions primarily as acne, pimples and a certain amount of a shallow and pustules, mainly in the face, a small amount occurs in the neck, chest and back.

in级(重度)主要皮损为深在性炎性丘疹和脓疱,发生于颜面、颈部、胸背部。 in stage (severe) deep primary lesions in inflammatory papules and pustules, it occurs in the face, neck, chest and back. 本发明实验患者共35例,其中男14例,女21例;年龄15〜36岁,病程最短1个月,最长4年,皮损程度达到III级的8例,II级的17例,I级的10例。 Experiment 35 cases of patients present invention, including 14 males, 21 females; age of 15~36 years, shortest duration of 1 month, up to 4 years, 8 cases lesions extent that stage III, 17 of the cases of grade II, 10 cases of grade I.

入选标准:具有典型的临床表现,符合上述寻常性痤疮的诊断标准, 一月 Inclusion criteria: a typical clinical presentation, diagnostic criteria in line with the aforementioned acne vulgaris in January

内未做任何药物治疗,无合并其他疾病。 Inside without making any medication, no other diseases.

剔除标准:对本品过敏者;长期应用皮质类固醇激素者。 Exclusion criteria: for this allergy; long-term use of corticosteroids person. 用药及观察方法:用棉签蘸取配好的复方擦剂,均匀涂于患处,面积略大 Treatment and observation methods: with a cotton swab dipped with a good compound liniments, uniformly applied to the lesion area slightly larger

于皮损,早、中、晚各一次,重症可每天四次,临睡前增加一次,疗程一个月。 In skin lesions, early, middle and late each time, can be severe or four times, once before going to sleep increased, one month course of treatment every day.

评分的方法:将临床表现炎症丘疹、脓庖按无一0分,轻一l分,中一2 Scoring method: clinical manifestations of inflammatory papules, pus kitchen press without a 0, a l light points, in a 2

分,重_3分,评分后累加起来既为临床得分,治疗后疗效指数=(治疗前得 Minutes, re-_3 minutes, add up the scores of both the clinical score, the Therapeutic Index = (obtained before treatment

分一治疗后得分)/治疗前得分xioox。 Score points after a treatment) / xioox scores before treatment.

疗效判定采用以下标准: 痊愈症状基本消失,疗效指数>95%; Determine the efficacy of the following criteria: cure symptoms disappeared, efficacy index> 95%;

显效症状明显好转,疗效指数60〜95%; 有效症状好转,疗效指数20〜60%; 无效疗效指数<20% Symptoms markedly improved efficacy index 60~95%; effective symptoms improved efficacy index 20~60%; valid efficacy index <20%

临床结果见下表: Clinical results in the table below:

<table>table see original document page 7</column></row> <table>从上表可知,本发明的药物总有效率为94.3%,治愈率为60%,治疗效显著,治愈率高,无副作用,药物用量小,疗程短、经济节约。 <Table> table see original document page 7 </ column> </ row> <table> be seen from the table, the drug of the present invention, the total effective rate was 94.3%, the cure rate was 60%, a significant therapeutic effect, high cure rate, no side effects, a small amount of the drug, short course, economical.

Claims (4)

1、一种治疗痤疮的中药复方制剂,其特征在于,主要由以下重量份数的原料制成: 人参3~15 珍珠粉0.1~5 金银花5~20 白芷3~15 苦杏仁4.5~25 蛇床子3~15 金沸草4.5~15 大黄3~30 黄芩3~20 丹参9~50 鸦胆子0.5~25 苦参4.5~20 野菊花9~15。 A traditional Chinese medicine in the treatment of acne, characterized in that the material mainly made of the following parts by weight: 3-15 ginseng pearl powder 0.1 ~ 5 5 ~ 20 Angelica honeysuckle 3 ~ 15 25 ~ 4.5 amygdalin Cnidium 3 ~ 15 ~ 15 4.5 gold boiling grass rhubarb Scutellaria 3 to 30 3 to 20 9 Salvia ~ ~ ~ 0.5 50 javanica 20 25 Sophora 4.5 chrysanthemum 9-15.
2、 如权利要求1所述的治疗痤疮的中药复方制剂,其特征在于,主要由以下重量份数的原料制成-人参5~10 珍珠粉0.2〜2 金银花5~15 白芷3~10苦杏仁5~20 蛇床子3~10 金沸草5〜10 大黄5~20黄苳5〜15 丹参10〜30 鸦胆子5〜25 苦参5〜15野菊花10〜15。 2, as claimed in traditional Chinese medicine to treat acne according to claim 1, characterized in that the material mainly made of the following parts by weight - 5 to 10 ginseng pearl powder 0.2~2 Angelica honeysuckle 5-15 3-10 amygdalin 5 ~ 20 ~ 3 Osthol gold boiling grass 10 5 ~ 10 5 ~ 20 rhubarb yellow paper cutters javanica 5~25 10~30 5~15 Salvia flavescens 5~15 chrysanthemum 10 ~ 15.
3、 如权利要求1或2所述治疗痤疮的中药复方制剂,其特征在于,还包括以下重量份数的原料:新氮酮0.25〜2 玫瑰花香精0.5~2 青豆多肽1〜3远红外纳米陶瓷粉0.01-2 薄荷脑0.02-5。 3, by traditional Chinese medicine as claimed in claim 1 or claim 2 in the treatment of acne, characterized by further comprising by weight parts of the starting material: New Azone 0.25~2 rose essence 0.5 ~ 2 ~ 3 polypeptide beans far infrared nano ceramic powder 0.01-2 0.02-5 menthol.
4、治疗痤疮的中药复方制剂的制备方法,其特征在于,包括以下步骤:(1) 、取人参3〜15重量份、金银花5〜20重量份、白芷3〜15重量份、苦杏仁4.5〜25重量份、蛇床子3〜15重量份、金沸草4.5-15重量份、大黄3~30 重量份、黄苳3~20重量份、丹参9~50重量份、鸦胆子0.5〜25重量份、苦参4.5〜20 重量份、野菊花9〜15重量份清洗、粉碎,加入6〜8倍重量的水煮沸,煎煮1〜3 小时,取滤液;(2) 、滤渣再加4〜6倍重量的水煎煮40min〜1小时,取滤液;(3) 、合并两次滤液,精滤后离心,静置30min〜l小时,抽取上清液, 浓縮至80'C下的相对密度为U0〜l,25;(4) 、加入珍珠粉0.1〜5重量份、薄荷脑0.02-5重量份、远红外纳米陶瓷粉0.01〜2重量份、青豆多肽1〜3重量份、新氮酮0.25-2重量份,调配加入玫瑰花香精0.5~2重量份,加蒸馏水制成8(TC下相对密度为1.05〜1.15的药液, 瞬间高温灭菌; 4, preparation of compound preparation for treating acne medicine, characterized by comprising the steps of: (1), 3~15 parts by weight of ginseng, honeysuckle, 5~20 parts by weight, 3~15 parts by weight angelica, bitter almond 4.5~ 25 parts by weight, Cnidium 3~15 parts by weight, 4.5-15 parts by weight gold boiling grass, 3 to 30 parts by weight of rhubarb, yellow paper cutters 3 to 20 parts by weight, 9 to 50 parts by weight of Salvia miltiorrhiza, 0.5~25 parts by weight javanica , 4.5~20 parts by weight flavescens, chrysanthemum 9~15 parts by weight of cleaning, crushing, addition of 6 ~ 8 times the weight of boiling water, boiling 1~3 hours, the filtrate; (2), residues plus 4 ~ 6 times its weight of boiling water 40min~1 hours, the filtrate; (3), two filtrates were combined, centrifuged after fine filtration, allowed to stand 30min~l hours, the supernatant was extracted, concentrated to the relative density at 80'C is U0~l, 25; (4), 0.1~5 parts by weight was added pearl powder, menthol, 0.02 to 5 parts by weight, far infrared nano 0.01~2 parts by weight of ceramic powder, green beans polypeptide 1~3 parts by weight azone new 0.25 to 2 parts by weight, the formulation was added 0.5 parts by weight to 2 rose flavor, made from distilled water 8 (TC lower relative density of the liquid 1.05~1.15, instantaneous high temperature sterilization; (5) 、加入占药液重量40〜60%的甘油和占药液重量40〜60%的乙醇即制成中药复方制剂。 (5), 40~60 wt% drug solution was added accounting glycerol and 40~60% by weight of the chemical liquid accounts for ethanol that is made by traditional Chinese medicine.
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CN101890117B (en) * 2010-07-19 2012-02-01 伍平 Traditional Chinese medicinal composition for treating acnes
CN103463202B (en) * 2013-09-18 2015-07-08 吴秋业 Oral traditional Chinese medicine preparation for treating acne and production process of oral traditional Chinese medicine preparation for treating acne
CN103989890A (en) * 2014-05-18 2014-08-20 洛阳市安普生物科技有限公司 Anti-fungus cream externally applied to skin
CN105362480A (en) * 2014-08-12 2016-03-02 柯宏 External application traditional Chinese medicine composition for acne prevention and treatment
CN104771461A (en) * 2015-03-16 2015-07-15 曾玉莹 Traditional Chinese medicine spraying agent for treating acne and preparation method thereof
CN105012688A (en) * 2015-06-30 2015-11-04 青岛海之星生物科技有限公司 Traditional Chinese medicine ointment used for treating keratosis pilaris, and preparation method thereof
CN105232589A (en) * 2015-08-12 2016-01-13 万太保 Compound acne treatment mixture and preparation method thereof
CN105168360A (en) * 2015-08-28 2015-12-23 吉林大学 Compound plant extract liniment for treating acne and preparation method of compound plant extract liniment
CN106110064A (en) * 2016-07-21 2016-11-16 魏晓兵 Externally applied traditional Chinese medicine for removing acne

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