CN103720941A - Traditional Chinese medicinal onychomycosis soaking preparation - Google Patents
Traditional Chinese medicinal onychomycosis soaking preparation Download PDFInfo
- Publication number
- CN103720941A CN103720941A CN201310742077.1A CN201310742077A CN103720941A CN 103720941 A CN103720941 A CN 103720941A CN 201310742077 A CN201310742077 A CN 201310742077A CN 103720941 A CN103720941 A CN 103720941A
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- CN
- China
- Prior art keywords
- parts
- cortex
- agent
- tinea unguium
- flos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 208000010195 Onychomycosis Diseases 0.000 title claims abstract description 32
- 201000005882 tinea unguium Diseases 0.000 title claims abstract description 32
- 238000002360 preparation method Methods 0.000 title claims abstract description 5
- 238000002791 soaking Methods 0.000 title abstract 2
- 241000628997 Flos Species 0.000 claims abstract description 36
- 239000003814 drug Substances 0.000 claims description 23
- 239000006260 foam Substances 0.000 claims description 23
- 238000005406 washing Methods 0.000 claims description 23
- 239000003795 chemical substances by application Substances 0.000 claims description 22
- 210000000582 semen Anatomy 0.000 claims description 11
- 235000021419 vinegar Nutrition 0.000 claims description 7
- 239000000052 vinegar Substances 0.000 claims description 7
- 230000003203 everyday effect Effects 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
- 235000016811 Biondella Nutrition 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 241001112007 Eriocaulaceae Species 0.000 abstract 1
- 241000558306 Gynocardia odorata Species 0.000 abstract 1
- 241001180876 Saposhnikovia Species 0.000 abstract 1
- 241000246044 Sophora flavescens Species 0.000 abstract 1
- 241001530209 Swertia Species 0.000 abstract 1
- 229940037003 alum Drugs 0.000 abstract 1
- 210000004905 finger nail Anatomy 0.000 description 7
- 238000011282 treatment Methods 0.000 description 7
- 241000233866 Fungi Species 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 210000002683 foot Anatomy 0.000 description 5
- 206010067197 Tinea manuum Diseases 0.000 description 4
- 238000004362 fungal culture Methods 0.000 description 4
- 230000002538 fungal effect Effects 0.000 description 4
- 230000000144 pharmacologic effect Effects 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 231100001274 therapeutic index Toxicity 0.000 description 4
- 201000004647 tinea pedis Diseases 0.000 description 4
- 208000003251 Pruritus Diseases 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 230000008719 thickening Effects 0.000 description 3
- 229920000832 Cutin Polymers 0.000 description 2
- 206010034016 Paronychia Diseases 0.000 description 2
- 241000029132 Paronychia Species 0.000 description 2
- 208000002474 Tinea Diseases 0.000 description 2
- 230000000843 anti-fungal effect Effects 0.000 description 2
- 229940121375 antifungal agent Drugs 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 238000000386 microscopy Methods 0.000 description 2
- 244000045947 parasite Species 0.000 description 2
- 230000035935 pregnancy Effects 0.000 description 2
- 241001480043 Arthrodermataceae Species 0.000 description 1
- 206010012504 Dermatophytosis Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 241001460074 Microsporum distortum Species 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001716 anti-fugal effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 229940088529 claritin Drugs 0.000 description 1
- 230000037304 dermatophytes Effects 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 238000011866 long-term treatment Methods 0.000 description 1
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 description 1
- 210000000282 nail Anatomy 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000004906 toe nail Anatomy 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicinal onychomycosis soaking preparation. The preparation comprises the following components in parts by weight: 8-13 parts of felwort, 8-13 parts of cortex phellodendri, 8-13 parts of dictamni cortex, 8-13 parts of sophora flavescens, 8-13 parts of fructus cnidii, 8-13 parts of pipewort, 8-13 parts of herba schizonepetae, 8-13 parts of divaricate saposhnikovia root, 8-13 parts of cortex acanthopanacis, 8-13 parts of cortex lycii radicis, 2-7 parts of safflower, 8-13 parts of sculellaria barbata, 8-13 parts of chaulmoogra, 26-31 parts of dried alum, 26-31 parts of spina gleditsiae, and 2-7 parts of flos caryophylli.
Description
technical field
The present invention relates to a kind of Chinese medicine formula, specifically a kind of foam washing agent that is used for the treatment of tinea unguium.
technical background
Tinea unguium, is commonly called as tinea unguium, refers to the disease causing under dermatophytes infringement deck or first.Patient's great majority of tinea manus and pedis and tinea unguium infect for merging antibacterial, scytitis is more obvious, in prior art, treat in the Chinese medicine lotion medicine of tinea manus and pedis or tinea unguium, the component of stripping off cutin is more, antifungal component is relatively less, zest to skin is stronger, and long-term treatment meeting makes skin very responsive.
Summary of the invention
The object of this invention is to provide a kind of better safer Traditional medicine bubble lotion of tinea unguium curative effect that is used for the treatment of.
For realizing above object, a kind of Chinese medicine tinea unguium foam washing of the present invention agent, its component and weight portion are: Radix Gentianae 8-13, Cortex Phellodendri 8-13, Cortex Dictamni 8-13, Radix Sophorae Flavescentis 8-13, Fructus Cnidii 8-13, Flos Eriocauli 8-13, Herba Schizonepetae 8-13, Radix Saposhnikoviae 8-13, Cortex Acanthopancis 8-13, Cortex Lycii 8-13, Flos Carthami 2-7, Herba Scutellariae Barbatae 8-13, Semen Hydnocarpi 8-13, dried Alumen 26-31, Spina Gleditsiae 26-31, Flos Caryophylli 2-7.
Further, its component and weight portion are: Radix Gentianae 9-12, Cortex Phellodendri 9-12, Cortex Dictamni 9-12, Radix Sophorae Flavescentis 9-12, Fructus Cnidii 9-12, Flos Eriocauli 9-12, Herba Schizonepetae 9-12, Radix Saposhnikoviae 9-12, Cortex Acanthopancis 9-12, Cortex Lycii 9-12, Flos Carthami 3-6, Herba Scutellariae Barbatae 9-12, Semen Hydnocarpi 9-12, dried Alumen 27-30, Spina Gleditsiae 27-30, Flos Caryophylli 3-6.
Further, its component and weight portion are: Radix Gentianae 12, Cortex Phellodendri 12, Cortex Dictamni 12, Radix Sophorae Flavescentis 12, Fructus Cnidii 12, Flos Eriocauli 12, Herba Schizonepetae 12, Radix Saposhnikoviae 12, Cortex Acanthopancis 12, Cortex Lycii 12, Flos Carthami 6, Herba Scutellariae Barbatae 12, Semen Hydnocarpi 12, dried Alumen 30, Spina Gleditsiae 30, Flos Caryophylli 6.
Further, its preparation method is: by proportioning mix homogeneously, add the vinegar of 1500-2000 weight portion to soak 3 days described each component, make the agent of tinea unguium foam washing.
Further, its using method is: get the agent of tinea unguium foam washing and soak affected part, soak 1-2 hour every day, use continuously after 5 days and change medicament, SM 2-3 month.
The beneficial effect that the present invention produces is; Chinese medicine tinea unguium foam washing of the present invention agent has increased antifungal and has strengthened chemosmotic medicine on the basis of existing formula; antiinflammatory, Claritin have been increased; as Radix Gentianae, Cortex Phellodendri, Cortex Dictamni, Radix Sophorae Flavescentis, Flos Eriocauli, Flos Caryophylli; existing good antifungic action, can protect again skin, avoids skin to come to harm; make skin can tolerate medicine, played good therapeutic effect.
In the formula of Chinese medicine tinea unguium foam washing of the present invention agent, Radix Gentianae, Cortex Phellodendri, Cortex Dictamni, Radix Sophorae Flavescentis, Fructus Cnidii, Semen Hydnocarpi, Flos Eriocauli, Flos Caryophylli have heat clearing and damp drying, killing parasites for relieving itching effect, modern pharmacological research medicine-feeding all has inhibitory action to various skin fungus, and said medicine also has good antiinflammatory, anti-allergic effects.The modern pharmacological research of Herba Schizonepetae, Radix Saposhnikoviae can make sweat gland secretion vigorous, and vigorous skin blood impels skin ulcer tinea to become disorganization and Absorption.Cortex Acanthopancis, Cortex Lycii, Flos Carthami, Herba Scutellariae Barbatae modern pharmacological research have horny layer softening, and vigorous blood increases the osmosis of fingernail and skin.Spina Gleditsiae is controlled wind parasite killing, and property is extremely sharp keen, can attack away blood vessels, through sick institute.Dried Alumen can removing dampness sore, and modern pharmacological research has antiinflammatory, convergence, antiseptical effect.Vinegar has sterilization, strips off cutin, promotes the effect of drug osmotic.
The specific embodiment
Embodiment 1: get Radix Gentianae 8g, Cortex Phellodendri 8g, Cortex Dictamni 8g, Radix Sophorae Flavescentis 8g, Fructus Cnidii 8g, Flos Eriocauli 8g, Herba Schizonepetae 8g, Radix Saposhnikoviae 8g, Cortex Acanthopancis 8g, Cortex Lycii 8g, Flos Carthami 2g, Herba Scutellariae Barbatae 8g, Semen Hydnocarpi 8g, dried Alumen 26g, Spina Gleditsiae 26g, Flos Caryophylli 2g mix homogeneously, add 1500g vinegar to soak 3 days, make the agent of tinea unguium foam washing.During treatment, get above-mentioned tinea unguium foam washing agent and soak affected part, soak 1-2 hour every day, use continuously after 5 days and change medicament, SM 3 months.
Embodiment 2: get Radix Gentianae 9g, Cortex Phellodendri 9g, Cortex Dictamni 9g, Radix Sophorae Flavescentis 9g, Fructus Cnidii 9g, Flos Eriocauli 9g, Herba Schizonepetae 9g, Radix Saposhnikoviae 9g, Cortex Acanthopancis 9g, Cortex Lycii 9g, Flos Carthami 3g, Herba Scutellariae Barbatae 9g, Semen Hydnocarpi 9g, dried Alumen 27g, Spina Gleditsiae 27g, Flos Caryophylli 3g mix homogeneously, add 1500g vinegar to soak 3 days, make the agent of tinea unguium foam washing.During treatment, get above-mentioned tinea unguium foam washing agent and soak affected part, soak 1-2 hour every day, use continuously after 5 days and change medicament, SM 3 months.
Embodiment 3: get Radix Gentianae 12g, Cortex Phellodendri 12g, Cortex Dictamni 12g, Radix Sophorae Flavescentis 12g, Fructus Cnidii 12g, Flos Eriocauli 12g, Herba Schizonepetae 12g, Radix Saposhnikoviae 12g, Cortex Acanthopancis 12g, Cortex Lycii 12g, Flos Carthami 6g, Herba Scutellariae Barbatae 12g, Semen Hydnocarpi 12g, dried Alumen 30g, Spina Gleditsiae 30g, Flos Caryophylli 6g mix homogeneously, add 1500g vinegar to soak 3 days, make the agent of tinea unguium foam washing.During treatment, get above-mentioned tinea unguium foam washing agent and soak affected part, soak 1-2 hour every day, use continuously after 5 days and change medicament, SM 3 months.
Embodiment 4: get Radix Gentianae 13g, Cortex Phellodendri 13g, Cortex Dictamni 13g, Radix Sophorae Flavescentis 13g, Fructus Cnidii 13g, Flos Eriocauli 13g, Herba Schizonepetae 13g, Radix Saposhnikoviae 13g, Cortex Acanthopancis 13g, Cortex Lycii 13g, Flos Carthami 7g, Herba Scutellariae Barbatae 13g, Semen Hydnocarpi 13g, dried Alumen 31g, Spina Gleditsiae 31g, Flos Caryophylli 7g mix homogeneously, add 1500g vinegar to soak 3 days, make the agent of tinea unguium foam washing.During treatment, get above-mentioned tinea unguium foam washing agent and soak affected part, soak 1-2 hour every day, use continuously after 5 days and change medicament, SM 3 months.
efficacy assessment standard:
Recovery from illness: symptom, sign disappear substantially, therapeutic index >=90%, negative fungal examination, fungal culture feminine gender.
Effective: symptom, sign obviously alleviate, therapeutic index is 60%-89%, negative fungal examination, fungal culture feminine gender.
Effective: symptom, sign are improved, and therapeutic index is 20%-59%, negative fungal examination or the positive, fungal culture is negative or positive.
Invalid: symptom, sign are not improved, therapeutic index≤19%, negative fungal examination or the positive, positive for fungi culture.
disease wholistic therapy effect:
Treatment tinea unguium patient 60 examples, recovery from illness 50 examples, effective 6 examples, effective 4 examples, total effective rate 100%.
medical record is given an example:
Example 1: patient goes into business certain, man, 32 years old, is engaged in cook and works more than 10 years, first visit on March 28 in 2010.Both hands toe first thickening, muddiness, deck becomes fragile, and merges paronychia, and full hand-foot skin plumpness is coarse, the desquamation of chapping.Hand-foot skin and fingernail microscopy feminine gender, foot skin skin and toenail are cultivated as yeast infection, are diagnosed as tinea unguium and merge tinea manus and pedis and paronychia.Give said method and soak 3 months, toe, fingernail recover normal, and hand-foot skin is as usual, fungus microscope examination and cultivation total negative, and disease recovery from illness, follows up a case by regular visits to not recurrence in 2 years.
Example 2: patient Zhang, female, 30 years old, evening was pregnant, first visit on October 22 in 2008.Both hands toe seam vesicle, pruritus 5 months, fingernail thickening, flavescence, first separates 3 months.After pregnancy, feel brothers' webs pruritus, play papulovesicle, because the pregnancy period does not treat, after gradually development increase the weight of, and the flavescence of brothers' fingernail thickening examines, and gives brothers' webs and nail fungi microscopy and checks positive, fingernail fungal culture is dermatophytosis growth, is diagnosed as tinea manus and pedis and tinea unguium.Said method foam washing 3 months, it is normal that skin and fingernail recover, fungus microscope examination and cultivation total negative.
Claims (5)
1. a Chinese medicine tinea unguium foam washing agent, is characterized in that: its component and weight portion are: Radix Gentianae 8-13, Cortex Phellodendri 8-13, Cortex Dictamni 8-13, Radix Sophorae Flavescentis 8-13, Fructus Cnidii 8-13, Flos Eriocauli 8-13, Herba Schizonepetae 8-13, Radix Saposhnikoviae 8-13, Cortex Acanthopancis 8-13, Cortex Lycii 8-13, Flos Carthami 2-7, Herba Scutellariae Barbatae 8-13, Semen Hydnocarpi 8-13, dried Alumen 26-31, Spina Gleditsiae 26-31, Flos Caryophylli 2-7.
2. a kind of Chinese medicine tinea unguium foam washing according to claim 1 agent, is characterized in that: its component and weight portion are: Radix Gentianae 9-12, Cortex Phellodendri 9-12, Cortex Dictamni 9-12, Radix Sophorae Flavescentis 9-12, Fructus Cnidii 9-12, Flos Eriocauli 9-12, Herba Schizonepetae 9-12, Radix Saposhnikoviae 9-12, Cortex Acanthopancis 9-12, Cortex Lycii 9-12, Flos Carthami 3-6, Herba Scutellariae Barbatae 9-12, Semen Hydnocarpi 9-12, dried Alumen 27-30, Spina Gleditsiae 27-30, Flos Caryophylli 3-6.
3. a kind of Chinese medicine tinea unguium foam washing according to claim 2 agent, is characterized in that: its component and weight portion are: Radix Gentianae 12, Cortex Phellodendri 12, Cortex Dictamni 12, Radix Sophorae Flavescentis 12, Fructus Cnidii 12, Flos Eriocauli 12, Herba Schizonepetae 12, Radix Saposhnikoviae 12, Cortex Acanthopancis 12, Cortex Lycii 12, Flos Carthami 6, Herba Scutellariae Barbatae 12, Semen Hydnocarpi 12, dried Alumen 30, Spina Gleditsiae 30, Flos Caryophylli 6.
4. according to a kind of Chinese medicine tinea unguium foam washing agent described in claim 1-3 any one, it is characterized in that: its preparation method is: by proportioning mix homogeneously, add the vinegar of 1500-2000 weight portion to soak 3 days described each component, make the agent of tinea unguium foam washing.
5. a kind of Chinese medicine tinea unguium foam washing according to claim 4 agent, is characterized in that: its using method is: get the agent of tinea unguium foam washing and soak affected part, soak 1-2 hour every day, use continuously after 5 days and change medicament, SM 2-3 month.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310742077.1A CN103720941B (en) | 2013-12-30 | 2013-12-30 | The agent of a kind of Chinese medicine onychomycosis foam washing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310742077.1A CN103720941B (en) | 2013-12-30 | 2013-12-30 | The agent of a kind of Chinese medicine onychomycosis foam washing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103720941A true CN103720941A (en) | 2014-04-16 |
| CN103720941B CN103720941B (en) | 2016-06-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310742077.1A Expired - Fee Related CN103720941B (en) | 2013-12-30 | 2013-12-30 | The agent of a kind of Chinese medicine onychomycosis foam washing |
Country Status (1)
| Country | Link |
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| CN (1) | CN103720941B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989743A (en) * | 2014-05-07 | 2014-08-20 | 张红 | Drug for treating onychomycosis |
| CN105521285A (en) * | 2014-09-29 | 2016-04-27 | 陆永达 | External-application traditional Chinese medicine liquid for treating leuconychia |
| CN107184849A (en) * | 2017-06-20 | 2017-09-22 | 苏州市李良济健康产业有限公司 | It is a kind of to be used to treat ointment of onychomycosis and preparation method thereof |
| CN110721236A (en) * | 2019-10-15 | 2020-01-24 | 南方医科大学 | Traditional Chinese medicine composition for treating tinea manus and pedis and preparation thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1292268A (en) * | 2000-04-24 | 2001-04-25 | 缪振兴 | Medicine for curing tinea unguium |
| CN102274382A (en) * | 2011-07-05 | 2011-12-14 | 太仓宝甲堂健康咨询有限公司 | External Chinese medicinal material mixture for treating onychomycosis and whitlow |
| CN102755574A (en) * | 2012-06-13 | 2012-10-31 | 王建中 | Chinese medicine composition for treating onychomycosis |
-
2013
- 2013-12-30 CN CN201310742077.1A patent/CN103720941B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1292268A (en) * | 2000-04-24 | 2001-04-25 | 缪振兴 | Medicine for curing tinea unguium |
| CN102274382A (en) * | 2011-07-05 | 2011-12-14 | 太仓宝甲堂健康咨询有限公司 | External Chinese medicinal material mixture for treating onychomycosis and whitlow |
| CN102755574A (en) * | 2012-06-13 | 2012-10-31 | 王建中 | Chinese medicine composition for treating onychomycosis |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989743A (en) * | 2014-05-07 | 2014-08-20 | 张红 | Drug for treating onychomycosis |
| CN105521285A (en) * | 2014-09-29 | 2016-04-27 | 陆永达 | External-application traditional Chinese medicine liquid for treating leuconychia |
| CN107184849A (en) * | 2017-06-20 | 2017-09-22 | 苏州市李良济健康产业有限公司 | It is a kind of to be used to treat ointment of onychomycosis and preparation method thereof |
| CN110721236A (en) * | 2019-10-15 | 2020-01-24 | 南方医科大学 | Traditional Chinese medicine composition for treating tinea manus and pedis and preparation thereof |
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| Publication number | Publication date |
|---|---|
| CN103720941B (en) | 2016-06-08 |
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Inventor after: Liu Daihong Inventor after: Wang Yuchun Inventor before: Liu Daihong |
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Effective date of registration: 20181115 Address after: 408400 Chongqing, Nanchuan District Dongcheng Street East loop 179 flower and fruit District 1 building 27 shop Patentee after: Chongqing Bai Wei Zhen Pharmaceutical Co., Ltd. Address before: 266033 Department of Dermatology, Haici Medical Group, No. 4 Renmin Road, Qingdao City, Shandong Province Patentee before: Liu Daihong |
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Granted publication date: 20160608 Termination date: 20191230 |