CN1267223A - 抗癌症剂 - Google Patents
抗癌症剂 Download PDFInfo
- Publication number
- CN1267223A CN1267223A CN98808243A CN98808243A CN1267223A CN 1267223 A CN1267223 A CN 1267223A CN 98808243 A CN98808243 A CN 98808243A CN 98808243 A CN98808243 A CN 98808243A CN 1267223 A CN1267223 A CN 1267223A
- Authority
- CN
- China
- Prior art keywords
- gene
- mbp
- sequence
- protein
- carcinostatic agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4707—Muscular dystrophy
- C07K14/4708—Duchenne dystrophy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Marine Sciences & Fisheries (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Description
步骤 | 比活性(单位/蛋白质(μg)) | 产率(%) |
1.血清 | 0.009 | 100 |
2.Sepharose 4B-甘露聚糖1 | 19.7 | 4.5 |
3.Sepharose 4B-甘露聚糖2 | 70.9 | 51.5 |
4.Sepharose 4B-甘露聚糖3 | 79.5 | 43.6 |
5.Sepharose CL-6B | 160.6 | 29.6 |
Claims (11)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP239113/1997 | 1997-08-21 | ||
JP23911397 | 1997-08-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1267223A true CN1267223A (zh) | 2000-09-20 |
CN1106846C CN1106846C (zh) | 2003-04-30 |
Family
ID=17039998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN98808243A Expired - Fee Related CN1106846C (zh) | 1997-08-21 | 1998-08-19 | 抗癌症剂 |
Country Status (9)
Country | Link |
---|---|
US (1) | US7410953B2 (zh) |
EP (1) | EP1008351B1 (zh) |
JP (1) | JP3990736B2 (zh) |
KR (1) | KR100497849B1 (zh) |
CN (1) | CN1106846C (zh) |
AT (1) | ATE345139T1 (zh) |
AU (1) | AU8748198A (zh) |
DE (1) | DE69836428T2 (zh) |
WO (1) | WO1999010001A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1324046C (zh) * | 2004-11-24 | 2007-07-04 | 中国科学院大连化学物理研究所 | 一种具有抗hiv活性的蛋白和糖结合蛋白 |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6148198A (en) * | 1998-08-05 | 2000-11-14 | Ericsson Inc. | Method and apparatus for selecting a service provider |
DE60009896T2 (de) | 1999-05-14 | 2005-04-21 | Steffen Thiel | Neue indikationen für mannan-binding lectin (mbl) zur behandlung von immungeschwächten patienten |
EP1539964B1 (en) * | 2002-09-10 | 2006-12-27 | Natlmmune A/S | Collectin-complement activating protein chimeras |
US20090088364A1 (en) * | 2004-12-23 | 2009-04-02 | Puranam Usha Sarma | Pharmaceutical composition useful for the treatment of invasive pulmonary aspergillosis |
CA2632630C (en) | 2005-12-13 | 2016-12-06 | President And Fellows Of Harvard College | Scaffolds for cell transplantation |
LT2624873T (lt) | 2010-10-06 | 2020-03-10 | President And Fellows Of Harvard College | Įšvirkščiami, poras sudarantys hidrogeliai, skirti medžiagų pagrindo ląstelių terapijai |
ES2773895T3 (es) | 2012-04-16 | 2020-07-15 | Harvard College | Composiciones de sílice mesoporosa para modular las respuestas inmunitarias |
WO2015168379A2 (en) | 2014-04-30 | 2015-11-05 | President And Fellows Of Harvard College | Combination vaccine devices and methods of killing cancer cells |
CA3012602A1 (en) | 2015-01-30 | 2016-08-04 | President And Fellows Of Harvard College | Peritumoral and intratumoral materials for cancer therapy |
JP7094533B2 (ja) | 2015-04-10 | 2022-07-04 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 免疫細胞捕捉デバイスおよびその製造および使用方法 |
WO2017136837A1 (en) | 2016-02-06 | 2017-08-10 | President And Fellows Of Harvard College | Recapitulating the hematopoietic niche to reconstitute immunity |
JP6854530B2 (ja) * | 2016-02-16 | 2021-04-07 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 病原体ワクチンならびにその製造および使用方法 |
MX2018011865A (es) | 2016-03-30 | 2019-03-28 | Ab biosciences inc | Composiciones de inmunoglobulina intravenosa recombinante (rivig) y metodos para su produccion y uso. |
WO2018013797A1 (en) | 2016-07-13 | 2018-01-18 | President And Fellows Of Harvard College | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5833975A (en) | 1989-03-08 | 1998-11-10 | Virogenetics Corporation | Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence |
EP0234122A3 (en) * | 1986-02-21 | 1989-03-22 | Oncogen Limited Partnership | Tumor therapy with biologically active anti-tumor antibodies |
US5091178A (en) * | 1986-02-21 | 1992-02-25 | Oncogen | Tumor therapy with biologically active anti-tumor antibodies |
EP0375736B1 (en) * | 1987-08-20 | 1998-05-13 | Children's Medical Center Corporation | Nucleic acid fragments encoding mannose binding fragments of human mannose binding protein |
US5270199A (en) * | 1987-08-20 | 1993-12-14 | The Children's Medical Center Corporation | Human mannose-binding protein |
EP0568539A4 (en) * | 1990-11-06 | 1994-07-06 | Childrens Medical Center | Soluble mannose receptor peptides |
WO1997035619A1 (en) * | 1996-03-28 | 1997-10-02 | Genitrix, L.L.C. | Opsonin-enhanced cells, and methods of modulating an immune response to an antigen |
DK1084143T3 (da) * | 1998-06-10 | 2006-12-27 | Statens Seruminstitut | Oprensningsproces til fremstilling af mannanbindende lectin og et medicinsk MBL-produkt |
-
1998
- 1998-08-19 KR KR10-2000-7000331A patent/KR100497849B1/ko not_active IP Right Cessation
- 1998-08-19 JP JP51416599A patent/JP3990736B2/ja not_active Expired - Fee Related
- 1998-08-19 WO PCT/JP1998/003697 patent/WO1999010001A1/ja active IP Right Grant
- 1998-08-19 CN CN98808243A patent/CN1106846C/zh not_active Expired - Fee Related
- 1998-08-19 DE DE69836428T patent/DE69836428T2/de not_active Expired - Fee Related
- 1998-08-19 AT AT98938917T patent/ATE345139T1/de not_active IP Right Cessation
- 1998-08-19 EP EP98938917A patent/EP1008351B1/en not_active Expired - Lifetime
- 1998-08-19 AU AU87481/98A patent/AU8748198A/en not_active Abandoned
-
2001
- 2001-10-04 US US09/971,475 patent/US7410953B2/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1324046C (zh) * | 2004-11-24 | 2007-07-04 | 中国科学院大连化学物理研究所 | 一种具有抗hiv活性的蛋白和糖结合蛋白 |
Also Published As
Publication number | Publication date |
---|---|
JP3990736B2 (ja) | 2007-10-17 |
EP1008351A1 (en) | 2000-06-14 |
KR100497849B1 (ko) | 2005-06-29 |
ATE345139T1 (de) | 2006-12-15 |
KR20010021768A (ko) | 2001-03-15 |
US20020086817A1 (en) | 2002-07-04 |
DE69836428T2 (de) | 2007-09-27 |
WO1999010001A1 (fr) | 1999-03-04 |
US7410953B2 (en) | 2008-08-12 |
DE69836428D1 (de) | 2006-12-28 |
CN1106846C (zh) | 2003-04-30 |
EP1008351A4 (en) | 2004-11-10 |
AU8748198A (en) | 1999-03-16 |
EP1008351B1 (en) | 2006-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: TAKARA SHUZO HOLDING CO., LTD. Free format text: FORMER OWNER: TAKARA SHUZO CO., LTD. Effective date: 20040723 Owner name: TAKARA BIO INC. Free format text: FORMER OWNER: TAKARA SHUZO HOLDING CO., LTD. Effective date: 20040723 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20040723 Address after: Shiga Patentee after: TAKARA BIO Inc. Address before: Kyoto Japan Patentee before: Treasure wine HOLDING Corp. Effective date of registration: 20040723 Address after: Kyoto Japan Patentee after: Treasure wine HOLDING Corp. Address before: Kyoto Japan Patentee before: TAKARA SHUZO Co.,Ltd. |
|
ASS | Succession or assignment of patent right |
Owner name: TAKARA BIO INC. Free format text: FORMER OWNER: BOALIZ PRODUCTS CO., LTD. Effective date: 20040903 |
|
C41 | Transfer of patent application or patent right or utility model | ||
C56 | Change in the name or address of the patentee |
Owner name: BOALIZ PRODUCTS CO., LTD. Free format text: FORMER NAME OR ADDRESS: TAKARA SHUZO CO., LTD. |
|
CP03 | Change of name, title or address |
Address after: Kyoto Japan Patentee after: Treasure Wine Products Corp. Address before: Kyoto Japan Patentee before: TAKARA SHUZO Co.,Ltd. |
|
TR01 | Transfer of patent right |
Effective date of registration: 20040903 Address after: Shiga Patentee after: TAKARA BIO Inc. Address before: Kyoto Japan Patentee before: Treasure Wine Products Corp. |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20030430 Termination date: 20090921 |