CN1234300C - 一种营养保健液及其生产方法 - Google Patents
一种营养保健液及其生产方法 Download PDFInfo
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- CN1234300C CN1234300C CNB021394431A CN02139443A CN1234300C CN 1234300 C CN1234300 C CN 1234300C CN B021394431 A CNB021394431 A CN B021394431A CN 02139443 A CN02139443 A CN 02139443A CN 1234300 C CN1234300 C CN 1234300C
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Abstract
本发明公开了一种营养保健液的配方及生产方法，其特点是采用有白藜芦醇、辅酶Q10、VA、VB1、VB2、VC、VD、VE及烟酸和有机酸锌等营养素；是根据人体营养均衡原理把各组份及功能因子按比例混合，再经调配、均质、脱气、灭菌、灌装而成。本发明所制备的保健液营养成分高且均衡，易于人体充分吸收，具有抗疲劳和延缓衰老的作用；本发明具有储存期长、质量稳定、能加热饮用、消费不受季节影响的优点，并能添加各种天然组份成为多口味的营养保健液，适口范围广；还能生产浓缩型使消费面更广，为保健食品行业开创了更为大众化的种类。
Description
技术领域
本发明属于营养保健饮料配方的改进，尤其是功能性营养食品的配置，涉及生物化学技术领域。
背景技术
虽然我国目前有保健食品生产企业3000多家，品种上万，但每年的销售额仍在不断地增长。可见随着人们生活水平的不断提高，保健食品已成为不可逆转的健康消费的支柱产业。从国内外保健食品的发展过程看，保健食品分为三代：第一代为初级保健食品，仅根据食品中的营养素成分或强化的营养素来推知该类食品的功能，未经严格的实验证明或严格的科学论证；第二代保健食品需经动物和/或人体实验，证明其具有某种生理调节功能，其特定的功能有了科学的实验基础；第三代保健食品不仅其特定生理调节功能需经动物和/或人体实验证明其明确可靠，而且还需确知有该项功能的功效成份的化学结构及其含量，即具有功效成份明确、含量可以测定、作用机理清楚、研究资料充实、临床效果肯定的特点。目前国内的保健食品大部分都属于前两代，是以原来中草药保健品发展起来的，化学结构不清楚、作用机理不明确、技术含量低、不仅造成产品大量的重复和积压，而且浪费了财力。而真正属于第三代的保健食品并不多，尤其是保健饮料更是寥寥无几。如红牛饮料，其属果汁类维生素功能饮料，具有抗疲劳的作用；但其成份作用单一，未考虑机体养分平衡的因素，故使所添加的养分不能充分发挥作用。
发明内容
本发明的目的就是根据人体营养平衡的原理，提出一种具有抗疲劳和延缓衰老作用的营养保健液，具有化学结构清楚、作用机理明确的优点。
本发明的目的是按以下技术方案得以实现，本发明所提出的营养保健液是以水为基质，包括有果汁、营养素、甜味剂、乳化稳定剂；其特征在于，按100ml保健液计所述营养素的组成为，白藜芦醇2-8mg，辅酶Q105-20mg，VA40-100μg，VB10.07-0.3mg，VB20.07-0.3mg，Vc5-30mg，VD0.8-4μg，VE0.2-4mg，烟酸0.8-5mg，有机酸锌1-5mg；所述保健液是将以上各组分按比例混合溶解、搅拌均匀再经调配后均质得到；其理化指标为：总固形物≥10％，酒精度含量1-5％；总酸以柠檬酸计0.05-0.4％，甜度以蔗糖计6-14％，总糖3-6％，不允许有明显沉淀和分层。
本发明所述营养素组分还可以采用以下组合：白藜芦醇5-8mg，辅酶Q1010-20mg，VA40-80μg，VB10.1-0.2mg，VB20.1-0.2mg，Vc16-30mg，VD1-4μg，VE1-4mg，烟酸2-5mg，有机酸锌2-5mg。其中有机酸锌可以采用葡萄糖酸锌或是乳酸锌；甜味剂可以采用木糖醇或是甜菊糖；果汁可以采用橙汁、桔汁、猕猴桃汁、沙棘汁、野刺梨汁、苹果汁、菠萝汁、枣汁、葡萄汁、桃汁的任一种或是二种、甚至三种。乳化稳定剂可以选用黄原胶或卡拉胶、或琼脂等。
本发明所述营养保健液的生产方法为，将水和果汁及添加物按比例混合溶解，搅拌均匀再经调配后均质，再于真空条件下脱气后，采用超高温瞬间灭菌，灌装后即为成品；其中脂溶性维生素(VD、VA、VE)采用微胶囊原料，这样有利于溶解；而白藜芦醇采用醇溶方式前期处理；其中调配可以是对产品口味的调配和理化指标的调整，但需加乳化稳定剂。
本发明所提供营养保健液的配方是根据人体营养均衡原理，把各种营养成分及功能因子按科学配比组合，所生产的营养保健液营养成分高且均衡，易于被人体充分吸收；申请人试制的利君牌升态营养保健液经陕西省疾病预防控制中心鉴定，检验结果为：该保健液具有抗疲劳和延缓衰老的作用。本发明具有储存期长、质量稳定、能加热饮用、消费不受季节影响的优点，并能添加各种天然组份成为多口味的营养保健液，适口范围广；还能生产浓缩型使消费面更广，为保健食品行业开创了更为大众化的种类。
本发明营养保健液中所添加白藜芦醇(Resveratrol)具有抗菌、抗脂质过氧化、预防心脏病、抗癌、抗血小板凝集、血管松弛、降血脂和抗诱变的作用。白藜芦醇的抗衰老作用主要是通过抗氧化和清除自由基体现的，在浓度为1.3μg/ml时，能明显抑制大鼠红细胞的自氧化溶血和由H2O2引起的氧化溶血，对小鼠肝、脑、肾的体内外过氧脂质的产生有明显的抑制作用；在浓度为5×10-4mol/L时，儿乎完全抑制ADP和NADPH引起的线粒体的脂质过氧化；对Fenton反应产生的OH-和黄嘌呤-黄嘌呤氧化酶自由基发生系统产生的·O2有明显的抑制作用。白藜芦醇能抑制环氧合酶的活性，还能抑制脂氧合酶的作用产物5-羟色胺的生成。研究发现白藜芦醇具有提高细胞抗氧化的作用，若结合维生素C和维生素E则细胞的抗氧化能力将更强；白藜芦醇还有抗自由基，抑制H+-K+-ATP酶和降低excβ-D-葡萄糖苷酶活性的作用。在考虑到其他成分的共同作用，本发明拟定每天的服用量在4-10mg范围内更合适。
本发明营养保健液中所添加辅酶Q10别名泛醌10，是一种维生素或维生素类物质，广泛存在于动物细胞中，是人体内唯一能自身合成的脂溶性维生素，人体也可以从食品中获得。但人体中辅酶Q10的含量随年龄的变化而改变。人在20岁时组织中辅酶Q10含量达到最大，20岁以后随着年龄的增加人体内的含量逐步下降；77到81岁的老人与19-21岁的年轻人比较，心肌中辅酶Q10含量下降72％、心脏中下降58％、肾上腺中下降50％、肝脏中下降17％。目前研究认为辅酶Q10有着非常广泛的功能，例如抗衰老、抗肿瘤、促进精子形成、降低血压、防治口腔疾病等。研究证明辅酶Q10具有促进ATP合成，抗氧化和还原自由基的作用。并认为改善辅酶Q10缺乏则需要进行高于高于饮食中含量水平的大剂量补充；外源性补充可以有效地促进线粒体ATP合成，同时辅酶Q10还有广泛的抗氧化作用，有利于运动后机体机能的恢复。辅酶Q10具有清除自由基(OH·)的能力，可使氢氧自由基氧化成水。辅酶Q10可能会保护线粒体防止呼吸链的氧化，保持合成能量的细胞器的基因组织和结构的完整性并伴随功能寿命的增加；可能是亚硝酸钠诱导的脂质过氧化的抗氧化因子；使质膜恢复后，自由基还原反应也得到恢复；通过增加ATP合成而增强了慢速离子通道能力；可防止缺氧引起的心肌功能退化；有氧训练中氧化刺激对细胞辅酶Q10浓度的调节可增强抗自由基损伤的能力；浆膜辅酶Q10可能作为控制细胞生长的氧化还原系统中电子跨膜传递的载体等。
辅酶Q10还有增加有氧运动能力、维持神经和大脑功能作用。ATP是脑活动的直接能源，补充辅酶Q10可以增加脑细胞线粒体辅酶Q10含量，加强脑细胞线粒体功能。外源性补充辅酶Q10可以促进线粒体ATP合成和有助于线粒体功能损害后的ATP再合成。因此，在一个能量需求增加或能量供给不足的状态或二者同时存在的状态都将增加线粒体对辅酶Q10的需求。这是外源性补充辅酶Q10改善组织功能和抗损伤的理论基础之一，同样也是补充辅酶Q10增加运动能力的依据。实验证实辅酶Q10与人体的运动能力有关，通过对自行车运动员的试验发现，口服补充辅酶Q10提高了运动员对较重负荷的耐受力；补充辅酶Q10可以有效抑制运动引起的氧化损伤。综上所述，大量的实验说明辅酶Q10具有良好的抗疲劳、延缓衰老的功效，没有发现有毒副作用。本发明将辅酶Q10的用量拟定在10-20mg/d范围，相当于药用量的1/3。
维生素是维持人体正常生理功能所必需的物质，但一般不在体内合成。维生素或做为辅酶参与机体的基本代谢过程，或用于维持高度发育器官的功能。VB1与三羧酸循环有关；VB2与能量物质的氧化分解有关；烟酸与葡萄糖代谢有关；VA能维持正常的视觉功能和促进机体生长发育；VD能促进钙、磷的吸收及钙化，促进骨骼发育；VE具有很强的抗氧化作用是常用的抗衰老物质，还能促进辅酶Q10的吸收。Karl Folkers认为人体中的辅酶Q10的主要来源是生物合成，在17个步骤的合成过程中至少有7种维生素和多种微量元素参与；除了果汁中的矿物质外，配方中还添加了有机酸锌。本发明采用木糖醇作为甜味剂，既能提供能量，又能赋予产品愉快的口味，并且在体内代谢不受胰岛素调节，适合糖尿病患者以及不愿摄入过多能量的人士食用，是国际上广泛使用的营养甜味剂。除此之外，新的研究表明木糖醇具有双岐因子的功效和防止病人肺部细菌感染的药理作用。本发明采用食用酒精是用于助溶各种脂溶性物质和作为调味剂。添加量以溶解白藜芦醇最少需要量为依据。
本发明从配方总体来看，以沙棘为基料，配以功能因子白藜芦醇、辅酶Q10，可以促进ATP生成并通过抗氧化消除机体在代谢过程中产生的自由基，达到抗疲劳、延缓衰老的功效，添加多种维生素既有补充营养的作用，又有与两种功能因子相互促进和互相保护的作用，如VC和VE可相对解除白藜芦醇和辅酶Q10的被氧化，辅酶Q10也具有保护维生素E的作用，从而延长该产品的功效时间。同时，添加VA和VE可以相对解除现代人由于长期操作电脑所造成的不同程度的视疲劳。
具体实施方式
实例1.配制10公升沙棘汁营养保健液，先用8公升水将所有添加物溶解混合搅拌均匀；其中VA和VD采用进口的微胶囊原料，VE采用陕西天维公司生产的微胶囊原料；而白藜芦醇先用食用酒精溶解后再混合。所有添加物的加入量为：白藜芦醇0.3g、辅酶Q100.5g、VA5mg、VB120mg、VB220mg、VC2.4g、VD0.1mg、VE0.1g、烟酸0.32g、葡萄糖酸锌0.2g、沙棘汁1L、木糖醇800g、食用乙醇(50％)200ml、黄原胶160g。混合均匀后进行口味和理化指标的调配，然后用水将总量加至10公升，用均质机在20mpa条件下均质，再于真空条件下脱气，采用μHT121℃条件下瞬时灭菌4秒，通过灌装机灌装，即为成品。
实例2.配制20公升苹果汁营养保健液，其操作及工艺与例1相同，所不同的是添加物的组份：白藜芦醇1.2g、辅酶Q103g、VA16mg、VB120mg、VB220mg、VC2g、VD0.6mg、VE0.8g、烟酸0.24g、乳酸锌0.8g、苹果汁1.6L、甜菊糖3g、食用乙醇(60％)600ml、琼脂198g。
Claims (4)
1、一种营养保健液是以水为基质，包括有果汁、营养素、甜味剂、乳化稳定剂，其特征在于，所述保健液按100ml计其营养素的组成有：白藜芦醇2-8mg，辅酶Q105-20mg，VA40100μg，VB10.07-0.3mg，VB20.07-0.3mg，Vc5-30mg，VD0.8-4μg，VE0.2-4mg，烟酸0.8-5mg，有机酸锌1-5mg；所述保健液将以上各组分按比例混合溶解、搅拌均匀再经调配后均质得到；其保健液的理化指标为：总固形物≥10％，酒精度含量1-5％，总酸以柠檬酸计0.05-0.4％，甜度以蔗糖计6-14％，总糖3-6％，不允许有明显沉淀和分层；其中脂溶性维生素采用微胶囊原料，而白藜芦醇采用醇溶方式前期处理。
2、根据权利要求1所述的营养保健液，其特征在于，所述营养素的含量范围为：白藜芦醇5-8mg，辅酶Q1010-20mg，VA40-80μg，VB10.1-0.2mg，VB20.1-0.2mg，Vc16-30mg，VD14μg，VE1-4mg，烟酸2-5mg，有机酸锌2-5mg。
3、根据权利要求2所述的营养保健液，其特征在于，所述的果汁可以是橙汁、桔汁、猕猴桃汁、沙棘汁、野刺梨汁、苹果汁、菠萝汁、枣汁、葡萄汁、桃汁的任一种或是二种、或三种。
4、根据权利要求1所述营养保健液的生产方法，其特征在于，将水和果汁及添加物按比例混合溶解，搅拌均匀再经调配后均质，再于真空条件下脱气，经超高温瞬时灭菌后装罐，即为成品。
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| CN103126036A (zh) * | 2011-12-01 | 2013-06-05 | 冯武文 | 添加有白藜芦醇的饮品 |
| CN102640955B (zh) * | 2012-05-28 | 2013-09-25 | 西北农林科技大学 | 一种鲜枣果汁加工方法 |
| CN103504445A (zh) * | 2012-06-25 | 2014-01-15 | 蔡洪亮 | 一种添加白藜芦醇、原花青素的饮品 |
| CN102894249B (zh) * | 2012-09-06 | 2014-01-08 | 广东省农业科学院农业生物技术研究所 | 一种缓解体力疲劳的营养液及其制备方法 |
| CN102885360A (zh) * | 2012-11-07 | 2013-01-23 | 广州国宇医药科技有限公司 | 一种改善记忆的果蔬饮品 |
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| CN106261265B (zh) * | 2016-08-16 | 2020-01-10 | 中州大学 | 一种淫羊藿抗疲劳运动饮料及其制备方法 |
| CN111387393B (zh) * | 2020-05-07 | 2022-09-20 | 北京维泰力特生物医药有限公司 | 一种含有小分子肽、白藜芦醇和花青素的饮料及其制备方法 |
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