CN1230164C - (S)－2－(苄基氨基甲基)－2,3,8,9－四氢－7H－1,4－二英并[2,3－e]吲哚－8－酮和精神抑制药的用于治疗或预防精神病的新的治疗剂组合物 - Google Patents
(S)－2－(苄基氨基甲基)－2,3,8,9－四氢－7H－1,4－二英并[2,3－e]吲哚－8－酮和精神抑制药的用于治疗或预防精神病的新的治疗剂组合物 Download PDFInfo
- Publication number
- CN1230164C CN1230164C CNB008169527A CN00816952A CN1230164C CN 1230164 C CN1230164 C CN 1230164C CN B008169527 A CNB008169527 A CN B008169527A CN 00816952 A CN00816952 A CN 00816952A CN 1230164 C CN1230164 C CN 1230164C
- Authority
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- China
- Prior art keywords
- antipsychotic drug
- methyl
- benzylamino
- indol
- application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
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- Medicinal Chemistry (AREA)
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- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45860799A | 1999-12-10 | 1999-12-10 | |
| US09/458,607 | 1999-12-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1409633A CN1409633A (zh) | 2003-04-09 |
| CN1230164C true CN1230164C (zh) | 2005-12-07 |
Family
ID=23821437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB008169527A Expired - Lifetime CN1230164C (zh) | 1999-12-10 | 2000-12-07 | (S)－2－(苄基氨基甲基)－2,3,8,9－四氢－7H－1,4－二英并[2,3－e]吲哚－8－酮和精神抑制药的用于治疗或预防精神病的新的治疗剂组合物 |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1235570A2 (fr) |
| JP (1) | JP5557409B2 (fr) |
| KR (1) | KR100772854B1 (fr) |
| CN (1) | CN1230164C (fr) |
| AR (1) | AR026756A1 (fr) |
| AU (1) | AU784211B2 (fr) |
| BR (1) | BR0016168A (fr) |
| CA (1) | CA2396351C (fr) |
| CZ (1) | CZ20021880A3 (fr) |
| EA (1) | EA005002B1 (fr) |
| HK (1) | HK1045942A1 (fr) |
| HU (1) | HUP0203309A3 (fr) |
| IL (2) | IL149669A0 (fr) |
| MX (1) | MXPA02005649A (fr) |
| NO (1) | NO20022739D0 (fr) |
| NZ (1) | NZ519381A (fr) |
| PL (1) | PL355292A1 (fr) |
| TW (1) | TWI222864B (fr) |
| WO (1) | WO2001041750A2 (fr) |
| ZA (1) | ZA200205484B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101409724B1 (ko) | 2003-10-29 | 2014-06-19 | 와이어쓰 엘엘씨 | 아플린도어 및 이의 유도체를 포함하는 서방성 약제학적조성물 |
| JP2008530229A (ja) | 2005-02-17 | 2008-08-07 | ワイス | シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体 |
| ES2430622T3 (es) * | 2008-02-13 | 2013-11-21 | Targacept, Inc. | Combinación de agonistas nicotínicos alfa 7 y antipsicóticos |
Family Cites Families (3)
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|---|---|---|---|---|
| JP2987484B2 (ja) * | 1995-03-16 | 1999-12-06 | 大塚製薬 株式会社 | カルボスチリル誘導体の製造方法 |
| US5756532A (en) * | 1995-11-06 | 1998-05-26 | American Home Products Corporation | Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives |
| GB9627005D0 (en) * | 1996-12-27 | 1997-02-12 | Knoll Ag | Therapeutic agents |
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2000
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- 2000-12-07 CZ CZ20021880A patent/CZ20021880A3/cs unknown
- 2000-12-07 EP EP00982461A patent/EP1235570A2/fr not_active Withdrawn
- 2000-12-07 AU AU19490/01A patent/AU784211B2/en not_active Ceased
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- 2000-12-07 MX MXPA02005649A patent/MXPA02005649A/es active IP Right Grant
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- 2000-12-07 JP JP2001543095A patent/JP5557409B2/ja not_active Expired - Lifetime
- 2000-12-07 KR KR1020027007286A patent/KR100772854B1/ko not_active IP Right Cessation
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Also Published As
| Publication number | Publication date |
|---|---|
| AU1949001A (en) | 2001-06-18 |
| PL355292A1 (en) | 2004-04-05 |
| MXPA02005649A (es) | 2004-09-10 |
| WO2001041750A3 (fr) | 2002-02-14 |
| KR100772854B1 (ko) | 2007-11-02 |
| IL149669A0 (en) | 2002-11-10 |
| IL149669A (en) | 2006-06-11 |
| ZA200205484B (en) | 2003-12-31 |
| JP5557409B2 (ja) | 2014-07-23 |
| HK1045942A1 (zh) | 2002-12-20 |
| EA200200656A1 (ru) | 2002-12-26 |
| CZ20021880A3 (cs) | 2002-08-14 |
| BR0016168A (pt) | 2002-08-20 |
| EP1235570A2 (fr) | 2002-09-04 |
| WO2001041750A2 (fr) | 2001-06-14 |
| AR026756A1 (es) | 2003-02-26 |
| KR20030016207A (ko) | 2003-02-26 |
| JP2003516350A (ja) | 2003-05-13 |
| NO20022739L (no) | 2002-06-07 |
| CA2396351A1 (fr) | 2001-06-14 |
| HUP0203309A3 (en) | 2004-12-28 |
| NZ519381A (en) | 2004-04-30 |
| NO20022739D0 (no) | 2002-06-07 |
| CA2396351C (fr) | 2009-11-10 |
| TWI222864B (en) | 2004-11-01 |
| HUP0203309A2 (hu) | 2003-01-28 |
| EA005002B1 (ru) | 2004-10-28 |
| AU784211B2 (en) | 2006-02-23 |
| CN1409633A (zh) | 2003-04-09 |
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