HUP0203309A2 - (S)-2-(benzilamino-metil)-2,3,8,9-tetrahidro-7H-1,4-dioxino[2,3-e]indol-8-on és neuroleptikumok terápiás kombinációi pszichotikus rendellenességek kezelésére vagy megelőzésére és ezeket tartalmazó gyógyszerkészítmények - Google Patents

(S)-2-(benzilamino-metil)-2,3,8,9-tetrahidro-7H-1,4-dioxino[2,3-e]indol-8-on és neuroleptikumok terápiás kombinációi pszichotikus rendellenességek kezelésére vagy megelőzésére és ezeket tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0203309A2
HUP0203309A2 HU0203309A HUP0203309A HUP0203309A2 HU P0203309 A2 HUP0203309 A2 HU P0203309A2 HU 0203309 A HU0203309 A HU 0203309A HU P0203309 A HUP0203309 A HU P0203309A HU P0203309 A2 HUP0203309 A2 HU P0203309A2
Authority
HU
Hungary
Prior art keywords
disorders
dioxino
indol
phychotic
neuroleptics
Prior art date
Application number
HU0203309A
Other languages
English (en)
Inventor
Karen Lovell Marquis
Original Assignee
Wyeth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth filed Critical Wyeth
Publication of HUP0203309A2 publication Critical patent/HUP0203309A2/hu
Publication of HUP0203309A3 publication Critical patent/HUP0203309A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány (S)-2-(benzilamino-metil)-2,3,8,9-tetra<- >hidro-7H-1,4-dioxino[2,3-e]indol-8-on és egy antipszichotikus szer kombinációjára,ezt tartalmazó gyógyszerkészítményekre és termékekre, valamint ezekalkalmazására vonatkozik. A találmány szerinti kombinációfelhasználható pszichotikus rendellenességek, így skizofrénia,skizoaf<- >fektív rendellenességek és depresszió kezelésére. Ó
HU0203309A 1999-12-10 2000-12-07 Therapeutic combinations of (s)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro-7h-1,4-dioxino(2,3)-e indol-8-one and neuroleptics for treatment or prevention of phychotic disorders and pharmaceutical compositions containing them HUP0203309A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45860799A 1999-12-10 1999-12-10
PCT/US2000/033060 WO2001041750A2 (en) 1999-12-10 2000-12-07 Combinations of (s)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro-7h-1,4-dioxino(2,3)-e indol-8-one and neuroleptics

Publications (2)

Publication Number Publication Date
HUP0203309A2 true HUP0203309A2 (hu) 2003-01-28
HUP0203309A3 HUP0203309A3 (en) 2004-12-28

Family

ID=23821437

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203309A HUP0203309A3 (en) 1999-12-10 2000-12-07 Therapeutic combinations of (s)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro-7h-1,4-dioxino(2,3)-e indol-8-one and neuroleptics for treatment or prevention of phychotic disorders and pharmaceutical compositions containing them

Country Status (20)

Country Link
EP (1) EP1235570A2 (hu)
JP (1) JP5557409B2 (hu)
KR (1) KR100772854B1 (hu)
CN (1) CN1230164C (hu)
AR (1) AR026756A1 (hu)
AU (1) AU784211B2 (hu)
BR (1) BR0016168A (hu)
CA (1) CA2396351C (hu)
CZ (1) CZ20021880A3 (hu)
EA (1) EA005002B1 (hu)
HK (1) HK1045942A1 (hu)
HU (1) HUP0203309A3 (hu)
IL (2) IL149669A0 (hu)
MX (1) MXPA02005649A (hu)
NO (1) NO20022739D0 (hu)
NZ (1) NZ519381A (hu)
PL (1) PL355292A1 (hu)
TW (1) TWI222864B (hu)
WO (1) WO2001041750A2 (hu)
ZA (1) ZA200205484B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101409724B1 (ko) 2003-10-29 2014-06-19 와이어쓰 엘엘씨 아플린도어 및 이의 유도체를 포함하는 서방성 약제학적조성물
JP2008530229A (ja) 2005-02-17 2008-08-07 ワイス シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
ES2430622T3 (es) * 2008-02-13 2013-11-21 Targacept, Inc. Combinación de agonistas nicotínicos alfa 7 y antipsicóticos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2987484B2 (ja) * 1995-03-16 1999-12-06 大塚製薬 株式会社 カルボスチリル誘導体の製造方法
US5756532A (en) * 1995-11-06 1998-05-26 American Home Products Corporation Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
GB9627005D0 (en) * 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents

Also Published As

Publication number Publication date
AU1949001A (en) 2001-06-18
PL355292A1 (en) 2004-04-05
MXPA02005649A (es) 2004-09-10
WO2001041750A3 (en) 2002-02-14
KR100772854B1 (ko) 2007-11-02
IL149669A0 (en) 2002-11-10
IL149669A (en) 2006-06-11
ZA200205484B (en) 2003-12-31
CN1230164C (zh) 2005-12-07
JP5557409B2 (ja) 2014-07-23
HK1045942A1 (zh) 2002-12-20
EA200200656A1 (ru) 2002-12-26
CZ20021880A3 (cs) 2002-08-14
BR0016168A (pt) 2002-08-20
EP1235570A2 (en) 2002-09-04
WO2001041750A2 (en) 2001-06-14
AR026756A1 (es) 2003-02-26
KR20030016207A (ko) 2003-02-26
JP2003516350A (ja) 2003-05-13
NO20022739L (no) 2002-06-07
CA2396351A1 (en) 2001-06-14
HUP0203309A3 (en) 2004-12-28
NZ519381A (en) 2004-04-30
NO20022739D0 (no) 2002-06-07
CA2396351C (en) 2009-11-10
TWI222864B (en) 2004-11-01
EA005002B1 (ru) 2004-10-28
AU784211B2 (en) 2006-02-23
CN1409633A (zh) 2003-04-09

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees