CN1216640C - 人免疫缺陷病毒的活疫苗 - Google Patents

人免疫缺陷病毒的活疫苗 Download PDF

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Publication number
CN1216640C
CN1216640C CN998027014A CN99802701A CN1216640C CN 1216640 C CN1216640 C CN 1216640C CN 998027014 A CN998027014 A CN 998027014A CN 99802701 A CN99802701 A CN 99802701A CN 1216640 C CN1216640 C CN 1216640C
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CN
China
Prior art keywords
hiv
mice
reverse transcriptase
tat
plasmid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN998027014A
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English (en)
Chinese (zh)
Other versions
CN1290175A (zh
Inventor
M·S·伯内特
G·B·基托
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RESEARCH DEVELOPMENT FOUDATION
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RESEARCH DEVELOPMENT FOUDATION
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Application filed by RESEARCH DEVELOPMENT FOUDATION filed Critical RESEARCH DEVELOPMENT FOUDATION
Publication of CN1290175A publication Critical patent/CN1290175A/zh
Application granted granted Critical
Publication of CN1216640C publication Critical patent/CN1216640C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • External Artificial Organs (AREA)
CN998027014A 1998-02-06 1999-02-04 人免疫缺陷病毒的活疫苗 Expired - Fee Related CN1216640C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7394398P 1998-02-06 1998-02-06
US60/073,943 1998-02-06

Publications (2)

Publication Number Publication Date
CN1290175A CN1290175A (zh) 2001-04-04
CN1216640C true CN1216640C (zh) 2005-08-31

Family

ID=22116747

Family Applications (1)

Application Number Title Priority Date Filing Date
CN998027014A Expired - Fee Related CN1216640C (zh) 1998-02-06 1999-02-04 人免疫缺陷病毒的活疫苗

Country Status (13)

Country Link
EP (1) EP1061950B1 (enExample)
JP (1) JP2002502827A (enExample)
KR (1) KR20010040618A (enExample)
CN (1) CN1216640C (enExample)
AT (1) ATE287727T1 (enExample)
AU (1) AU744730B2 (enExample)
CA (1) CA2320489A1 (enExample)
DE (1) DE69923439D1 (enExample)
IL (1) IL137680A0 (enExample)
NZ (1) NZ506093A (enExample)
RU (1) RU2223784C2 (enExample)
WO (1) WO1999039735A1 (enExample)
ZA (1) ZA99912B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2802426B1 (fr) * 1999-12-15 2004-04-02 Neovacs Utilisation de proteines immunogenes immunosuppressives et/ou angiogeniques rendues inactives, pour la production d'iga secretoires
CN1549726A (zh) * 2000-07-31 2004-11-24 耶鲁大学 先天性免疫系统指导的疫苗
KR100447530B1 (ko) * 2001-08-14 2004-09-08 한국과학기술원 ＯｍｐＦ를 이용하여 목적 단백질을 대장균 세포외로분비생산하는 방법
EP1670505B1 (en) * 2003-09-18 2012-11-14 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Dna promoters and anthrax vaccines
EP1991264B1 (en) 2006-03-07 2015-01-07 Vaxinnate Corporation Compositions that include hemagglutinin, methods of making and methods of use thereof
CN101195823B (zh) * 2007-11-20 2010-06-02 华东理工大学 细菌表面展示系统、方法及应用
CN109207417A (zh) * 2018-09-19 2019-01-15 湖北省农业科学院畜牧兽医研究所 鸡白痢-j亚群禽白血病双重平板凝集抗原及其制备方法
WO2021178888A1 (en) * 2020-03-05 2021-09-10 University Of Maryland, Baltimore Live salmonella typhi vectors engineered to express cancer protein antigens and methods of use thereof
WO2025063261A1 (ja) * 2023-09-22 2025-03-27 塩野義製薬株式会社 ウイルス由来タンパク質をコードするポリヌクレオチド

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757013A (en) * 1983-07-25 1988-07-12 The Research Foundation Of State University Of New York Cloning vehicles for polypeptide expression in microbial hosts
EP0563323A4 (en) * 1990-12-19 1996-02-28 Epitope Inc Hiv reverse transcriptase vaccine
JP3100005B2 (ja) * 1992-07-28 2000-10-16 雪印乳業株式会社 ヒト免疫不全ウィルス感染・増殖抑制剤
WO1996011708A1 (en) * 1994-10-18 1996-04-25 Board Of Regents, The University Of Texas System Membrane expression of heterologous genes

Also Published As

Publication number Publication date
EP1061950B1 (en) 2005-01-26
AU3180199A (en) 1999-08-23
NZ506093A (en) 2003-08-29
DE69923439D1 (de) 2005-03-03
RU2223784C2 (ru) 2004-02-20
KR20010040618A (ko) 2001-05-15
AU744730B2 (en) 2002-02-28
ATE287727T1 (de) 2005-02-15
CN1290175A (zh) 2001-04-04
ZA99912B (en) 2000-08-07
WO1999039735A1 (en) 1999-08-12
CA2320489A1 (en) 1999-08-12
WO1999039735A9 (en) 2000-01-27
JP2002502827A (ja) 2002-01-29
IL137680A0 (en) 2001-10-31
EP1061950A4 (en) 2001-12-05
EP1061950A1 (en) 2000-12-27

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050831