CN1216602C - 用于治疗糖尿病的硫辛酸和共轭酸的组合 - Google Patents

用于治疗糖尿病的硫辛酸和共轭酸的组合 Download PDF

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Publication number
CN1216602C
CN1216602C CN018155413A CN01815541A CN1216602C CN 1216602 C CN1216602 C CN 1216602C CN 018155413 A CN018155413 A CN 018155413A CN 01815541 A CN01815541 A CN 01815541A CN 1216602 C CN1216602 C CN 1216602C
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CN
China
Prior art keywords
acid
carbon
dienoic acid
treatment
diabetes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN018155413A
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English (en)
Chinese (zh)
Other versions
CN1455670A (zh
Inventor
O·哈塞尔旺德
K·克劳默尔
K-U·鲍尔代纽斯
M·J·克拉特
L·施魏克特
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BASF SE
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BASF SE
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Publication date
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Publication of CN1455670A publication Critical patent/CN1455670A/zh
Application granted granted Critical
Publication of CN1216602C publication Critical patent/CN1216602C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN018155413A 2000-09-12 2001-09-11 用于治疗糖尿病的硫辛酸和共轭酸的组合 Expired - Fee Related CN1216602C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10045059A DE10045059A1 (de) 2000-09-12 2000-09-12 Therapeutische Kombination von Liponsäure und Konjuensäuren zur Behandlung diabetischer Störungen
DE10045059.8 2000-09-12

Publications (2)

Publication Number Publication Date
CN1455670A CN1455670A (zh) 2003-11-12
CN1216602C true CN1216602C (zh) 2005-08-31

Family

ID=7655916

Family Applications (1)

Application Number Title Priority Date Filing Date
CN018155413A Expired - Fee Related CN1216602C (zh) 2000-09-12 2001-09-11 用于治疗糖尿病的硫辛酸和共轭酸的组合

Country Status (10)

Country Link
US (1) US20030187058A1 (cg-RX-API-DMAC7.html)
EP (1) EP1317264B1 (cg-RX-API-DMAC7.html)
JP (1) JP2004508399A (cg-RX-API-DMAC7.html)
CN (1) CN1216602C (cg-RX-API-DMAC7.html)
AT (1) ATE271866T1 (cg-RX-API-DMAC7.html)
AU (1) AU2001284057A1 (cg-RX-API-DMAC7.html)
DE (2) DE10045059A1 (cg-RX-API-DMAC7.html)
DK (1) DK1317264T3 (cg-RX-API-DMAC7.html)
ES (1) ES2225593T3 (cg-RX-API-DMAC7.html)
WO (1) WO2002022111A2 (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8697109B2 (en) * 2000-08-16 2014-04-15 Encore Health, Llc Caged mercaptan and seleno-mercaptan compounds and methods of using them
US7914815B2 (en) * 2000-08-16 2011-03-29 Encore Health, Llc Method for delivery of pharmaceuticals for treating or preventing presbyopia
US7935332B2 (en) * 2000-08-16 2011-05-03 Encore Health, Llc Presbyopia treatment by lens alteration
US8647612B2 (en) * 2008-03-05 2014-02-11 Encore Health, Llc Dithiol compounds, derivatives, and treatment of presbyopia
US20050112113A1 (en) * 2000-08-16 2005-05-26 Till Jonathan S. Presbyopia treatment by lens alteration
ATE399474T1 (de) * 2004-03-06 2008-07-15 Cognis Ip Man Gmbh Use of unsaturated fatty acids for the reduction of appetite or food intake
GB0426264D0 (en) * 2004-11-30 2004-12-29 Trigen Ltd Compounds
JP4556061B2 (ja) * 2006-07-27 2010-10-06 ビーエイチエヌ株式会社 ヒアルロン酸産生増強剤
WO2008067403A2 (en) * 2006-11-28 2008-06-05 Encore Health Llc Presbyopia treatment by lens alteration
CN101396357B (zh) * 2007-09-29 2010-12-29 中国科学院上海生命科学研究院 硫辛酰胺在防治胰岛素抵抗中的用途
US9044439B2 (en) * 2008-03-05 2015-06-02 Encore Health, Llc Low dose lipoic and pharmaceutical compositions and methods
WO2009111635A2 (en) * 2008-03-05 2009-09-11 Encore Health, Llc Dithiol compounds, derivatives, and uses therefor
PL2442647T3 (pl) * 2009-06-15 2016-09-30 Związki ditiolowe, pochodne i ich zastosowania
US8410162B2 (en) 2009-06-15 2013-04-02 Encore Health Llc Choline esters
CN101671331B (zh) * 2009-09-29 2011-06-01 寿光富康制药有限公司 硫辛酰维格列汀及其制备方法与应用
JP5245061B2 (ja) * 2010-05-12 2013-07-24 ビーエイチエヌ株式会社 経口用老化防止剤及び美容方法
CA2924597A1 (en) 2013-09-19 2015-03-26 The Research Foundation For The State University Of New York Methods and materials for treating diabetes or liver steatosis
WO2015050809A1 (en) * 2013-10-01 2015-04-09 Novozymes A/S Processes of producing fermentation products
CN112641720A (zh) 2014-03-03 2021-04-13 诺华股份有限公司 硫辛酸胆碱酯组合物及使用方法
US10639322B2 (en) 2015-03-27 2020-05-05 The Research Foundation For The State University Of New York Methods and materials for reducing amyloid beta levels within a mammal

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4343593C2 (de) * 1993-12-21 1998-05-20 Asta Medica Ag Verwendung von R-(+)-alpha-Liponsäure, R-(-)-Dihydroliponsäure oder der Metabolite sowie deren Salze, Ester, Amide zur Behandlung kompensierter und dekompensierter Insulinresistenz
US5962030A (en) * 1997-03-07 1999-10-05 Akesis Pharmaceuticals, Inc. Dietary supplement and method of treatment for diabetic control
ATE310511T1 (de) * 1997-12-12 2005-12-15 Purdue Research Foundation Verwendung von konjugierten linoleinsäure zur behandlung von type ii diabetes
US6440931B1 (en) * 1999-02-23 2002-08-27 Natural Corporation Conjugated linoleic acid in treatment and prophylaxis of diabetes
US6288106B1 (en) * 1999-05-25 2001-09-11 Chronorx, Llc Processes for the synthesis and use of various α-lipoic acid complexes
US20020025310A1 (en) * 2000-02-02 2002-02-28 Bland Jeffrey S. Compositions and methods for promoting healthy joints

Also Published As

Publication number Publication date
DE10045059A1 (de) 2002-03-21
ES2225593T3 (es) 2005-03-16
AU2001284057A1 (en) 2002-03-26
EP1317264A2 (de) 2003-06-11
US20030187058A1 (en) 2003-10-02
EP1317264B1 (de) 2004-07-28
ATE271866T1 (de) 2004-08-15
DK1317264T3 (da) 2004-11-29
WO2002022111A2 (de) 2002-03-21
CN1455670A (zh) 2003-11-12
DE50103029D1 (de) 2004-09-02
JP2004508399A (ja) 2004-03-18
WO2002022111A3 (de) 2003-02-27

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050831

Termination date: 20200911