CN1185230C - N－取代的氨基甲酰氧基烷基－吡咯鎓衍生物 - Google Patents
N－取代的氨基甲酰氧基烷基－吡咯鎓衍生物 Download PDFInfo
- Publication number
- CN1185230C CN1185230C CNB008153299A CN00815329A CN1185230C CN 1185230 C CN1185230 C CN 1185230C CN B008153299 A CNB008153299 A CN B008153299A CN 00815329 A CN00815329 A CN 00815329A CN 1185230 C CN1185230 C CN 1185230C
- Authority
- CN
- China
- Prior art keywords
- methyl
- phenyl
- ethyl
- cyano
- triazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cephalosporin Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99121694 | 1999-11-02 | ||
| EP99121694.6 | 1999-11-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1387529A CN1387529A (zh) | 2002-12-25 |
| CN1185230C true CN1185230C (zh) | 2005-01-19 |
Family
ID=8239312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB008153299A Expired - Lifetime CN1185230C (zh) | 1999-11-02 | 2000-10-25 | N－取代的氨基甲酰氧基烷基－吡咯鎓衍生物 |
Country Status (22)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110128420A (zh) * | 2019-05-08 | 2019-08-16 | 阴启明 | 硫酸氢根/硫酸根型阴离子交换技术制备艾沙康唑鎓单硫酸盐的方法 |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY148805A (en) | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
| MX2010001730A (es) | 2007-08-21 | 2010-03-10 | Basilea Pharmaceutica Ag | Composicion antimicotica. |
| US9907812B2 (en) | 2011-06-22 | 2018-03-06 | Vyome Biosciences Pvt. Ltd. | Conjugate-based antifungal and antibacterial prodrugs |
| NZ714817A (en) | 2013-06-04 | 2017-07-28 | Vyome Biosciences Pvt Ltd | Coated particles and compositions comprising same |
| CN104230894B (zh) * | 2013-06-06 | 2016-08-24 | 南京华威医药科技开发有限公司 | 三唑类化合物 |
| JP6684810B2 (ja) * | 2014-12-30 | 2020-04-22 | ダウ アグロサイエンシィズ エルエルシー | 殺真菌剤としてのピコリンアミド化合物の使用 |
| CN106032356B (zh) * | 2015-03-13 | 2018-09-14 | 江苏正大丰海制药有限公司 | 一种[n-甲基-吡啶-2-基]氨基甲酸-1-氯乙酯的制备方法 |
| CN104974143A (zh) * | 2015-05-12 | 2015-10-14 | 深圳致君制药有限公司 | 一种季铵盐类化合物、其制备方法以及用途 |
| CN106467534B (zh) * | 2015-08-17 | 2019-10-11 | 江苏奥赛康药业有限公司 | 一种硫酸艾沙康唑鎓化合物及其药物组合物 |
| CN106467519B (zh) * | 2015-08-17 | 2019-08-13 | 南京华威医药科技集团有限公司 | 一种水溶性三唑化合物 |
| CN106565699B (zh) * | 2015-10-10 | 2019-07-26 | 江苏正大丰海制药有限公司 | 一种艾沙康唑硫酸盐晶体及其制备方法 |
| WO2018067702A1 (en) | 2016-10-04 | 2018-04-12 | Massachusetts Institute Of Technology | Bottlebrush copolymers and uses thereof |
| WO2018149359A1 (zh) * | 2017-02-17 | 2018-08-23 | 武汉朗来科技发展有限公司 | 三氮唑抗菌衍生物、其药物组合物和用途 |
| CN106916152B (zh) * | 2017-04-27 | 2019-09-17 | 扬子江药业集团有限公司 | 氧化还原反应制备艾沙康唑鎓单硫酸盐的方法 |
| WO2019006425A1 (en) | 2017-06-30 | 2019-01-03 | Massachusetts Institute Of Technology | IMAGING AGENTS OF BRUSH ARRAY STAR POLYMERS AND USES THEREOF |
| EP3645530A2 (en) | 2017-06-30 | 2020-05-06 | Massachusetts Institute of Technology | Branched multi-functional macromonomers and related polymers and uses thereof |
| US10368502B2 (en) | 2017-09-25 | 2019-08-06 | Multiple Energy Technologies Llc | Bioceramic and carbon-based hydroponic systems, methods and devices |
| CN110317165A (zh) * | 2018-03-28 | 2019-10-11 | 上海医药工业研究院 | 一种药物中间体2-甲胺基-3-吡啶甲醇的制备方法 |
| CN110551064B (zh) * | 2018-06-01 | 2021-01-01 | 重庆世森医药科技有限公司 | 艾沙康唑硫酸酯及其中间体的制备方法 |
| WO2020025553A1 (en) | 2018-08-01 | 2020-02-06 | Basilea Pharmaceutica International AG | Methods for purifying isavuconazonium sulfate |
| US10988491B2 (en) | 2018-08-17 | 2021-04-27 | Massachusetts Institute Of Technology | Degradable polymers of a cyclic silyl ether and uses thereof |
| EP4021576A1 (en) | 2019-08-26 | 2022-07-06 | Synthon B.V. | Isavuconazonium salts and process for preparing thereof |
| AU2020368453A1 (en) * | 2019-10-16 | 2022-04-21 | Massachusetts Institute Of Technology | Brush prodrugs and uses thereof |
| JP7454905B2 (ja) * | 2021-09-28 | 2024-03-25 | 旭化成ファーマ株式会社 | 有効成分であるイサブコナゾール又はそのプロドラッグを含有する真菌症治療及び／又は予防剤 |
| JP2023049010A (ja) | 2021-09-28 | 2023-04-07 | 旭化成ファーマ株式会社 | エアベント付き輸液フィルタを備える点滴静脈投与用輸液セット |
| EP4289840A1 (en) | 2022-06-07 | 2023-12-13 | Zaklady Farmaceutyczne Polpharma S.A. | A process for preparing isavuconazonium sulfate |
| WO2024094329A1 (en) | 2022-11-01 | 2024-05-10 | Basilea Pharmaceutica International Ag, Allschwil | Blister-packaged capsule preparation containing isavuconazonium sulfate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407129B1 (en) * | 1997-03-31 | 2002-06-18 | Takeda Chemical Industries, Ltd. | Azole compounds, their production and their use |
| JP3108997B2 (ja) * | 1997-03-31 | 2000-11-13 | 武田薬品工業株式会社 | アゾール化合物、その製造法および用途 |
| AU2931399A (en) * | 1998-03-06 | 1999-09-20 | F. Hoffmann-La Roche Ag | 3-(4-(4-cyanophenyl)thiazol-2-y))-1-(1h-1,2,4-triazol-1-yl) -butan-2-ol derivatives having antifungal activity |
-
2000
- 2000-10-25 CN CNB008153299A patent/CN1185230C/zh not_active Expired - Lifetime
- 2000-10-25 KR KR10-2002-7005574A patent/KR100449797B1/ko active Protection Beyond IP Right Term
- 2000-10-25 PT PT00992946T patent/PT1280795E/pt unknown
- 2000-10-25 WO PCT/EP2000/010524 patent/WO2001032652A2/en active Search and Examination
- 2000-10-25 DE DE60018989T patent/DE60018989T2/de not_active Expired - Lifetime
- 2000-10-25 CA CA2680292A patent/CA2680292C/en not_active Expired - Lifetime
- 2000-10-25 AU AU28352/01A patent/AU777859B2/en active Active
- 2000-10-25 DK DK00992946T patent/DK1280795T3/da active
- 2000-10-25 AT AT00992946T patent/ATE291575T1/de active
- 2000-10-25 ES ES00992946T patent/ES2238341T3/es not_active Expired - Lifetime
- 2000-10-25 CA CA002388320A patent/CA2388320C/en not_active Expired - Lifetime
- 2000-10-25 MX MXPA02004145A patent/MXPA02004145A/es active IP Right Grant
- 2000-10-25 BR BRPI0015254A patent/BRPI0015254C1/pt not_active IP Right Cessation
- 2000-10-25 EP EP00992946A patent/EP1280795B1/en not_active Expired - Lifetime
- 2000-10-25 TR TR2002/01205T patent/TR200201205T2/xx unknown
- 2000-10-25 JP JP2001534803A patent/JP3787307B2/ja not_active Expired - Lifetime
- 2000-10-31 AR ARP000105739A patent/AR029403A1/es active IP Right Grant
-
2002
- 2002-04-16 ZA ZA200203003A patent/ZA200203003B/xx unknown
-
2015
- 2015-12-29 FR FR15C0096C patent/FR15C0096I2/fr active Active
-
2016
- 2016-01-06 LU LU92939C patent/LU92939I2/xx unknown
- 2016-01-26 NL NL300791C patent/NL300791I1/nl unknown
- 2016-02-03 CY CY2016002C patent/CY2016002I2/el unknown
- 2016-02-26 BE BE2016C007C patent/BE2016C007I2/fr unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110128420A (zh) * | 2019-05-08 | 2019-08-16 | 阴启明 | 硫酸氢根/硫酸根型阴离子交换技术制备艾沙康唑鎓单硫酸盐的方法 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20050119 |