CN1183097C - 本芴醇衍生物,其中间体及其抗寄生的原生动物门和吸虫的用途 - Google Patents
本芴醇衍生物,其中间体及其抗寄生的原生动物门和吸虫的用途 Download PDFInfo
- Publication number
- CN1183097C CN1183097C CNB998096180A CN99809618A CN1183097C CN 1183097 C CN1183097 C CN 1183097C CN B998096180 A CNB998096180 A CN B998096180A CN 99809618 A CN99809618 A CN 99809618A CN 1183097 C CN1183097 C CN 1183097C
- Authority
- CN
- China
- Prior art keywords
- formula
- compound
- salt
- acid
- substituents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/38—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH135198 | 1998-06-25 | ||
| CH1351/1998 | 1998-06-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1312794A CN1312794A (zh) | 2001-09-12 |
| CN1183097C true CN1183097C (zh) | 2005-01-05 |
Family
ID=4208448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB998096180A Expired - Lifetime CN1183097C (zh) | 1998-06-25 | 1999-06-23 | 本芴醇衍生物,其中间体及其抗寄生的原生动物门和吸虫的用途 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6329552B2 (https=) |
| EP (1) | EP1089961B1 (https=) |
| JP (1) | JP4355450B2 (https=) |
| CN (1) | CN1183097C (https=) |
| AT (1) | ATE259346T1 (https=) |
| AU (1) | AU4776399A (https=) |
| BR (1) | BRPI9912208B8 (https=) |
| CA (1) | CA2335685C (https=) |
| CO (1) | CO5040050A1 (https=) |
| ES (1) | ES2216528T3 (https=) |
| ID (1) | ID27500A (https=) |
| MY (1) | MY117662A (https=) |
| PE (1) | PE20000703A1 (https=) |
| PT (1) | PT1089961E (https=) |
| TW (2) | TW200528419A (https=) |
| WO (1) | WO1999067197A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104093689A (zh) * | 2012-01-31 | 2014-10-08 | 剑桥显示技术有限公司 | 聚合物 |
| CN111320547B (zh) * | 2020-04-03 | 2022-05-20 | 南京昊绿生物科技有限公司 | 一种苯芴醇-d9的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1029680C (zh) * | 1988-11-10 | 1995-09-06 | 军事医学科学院微生物流行病研究所 | 抗疟新药苯芴醇的合成新工艺 |
| CN1058717A (zh) * | 1990-08-08 | 1992-02-19 | 中国人民解放军军事医学科学院微生物流行病研究所 | 抗疟新药—复方蒿甲醚及其制备方法 |
-
1999
- 1999-06-11 CO CO99036913A patent/CO5040050A1/es unknown
- 1999-06-23 ES ES99931151T patent/ES2216528T3/es not_active Expired - Lifetime
- 1999-06-23 CA CA002335685A patent/CA2335685C/en not_active Expired - Lifetime
- 1999-06-23 MY MYPI99002590A patent/MY117662A/en unknown
- 1999-06-23 AU AU47763/99A patent/AU4776399A/en not_active Abandoned
- 1999-06-23 PE PE1999000560A patent/PE20000703A1/es not_active IP Right Cessation
- 1999-06-23 PT PT99931151T patent/PT1089961E/pt unknown
- 1999-06-23 EP EP99931151A patent/EP1089961B1/en not_active Expired - Lifetime
- 1999-06-23 BR BRPI9912208A patent/BRPI9912208B8/pt not_active IP Right Cessation
- 1999-06-23 ID IDW20002736A patent/ID27500A/id unknown
- 1999-06-23 AT AT99931151T patent/ATE259346T1/de active
- 1999-06-23 JP JP2000555853A patent/JP4355450B2/ja not_active Expired - Lifetime
- 1999-06-23 CN CNB998096180A patent/CN1183097C/zh not_active Expired - Lifetime
- 1999-06-23 WO PCT/EP1999/004355 patent/WO1999067197A1/en not_active Ceased
- 1999-07-13 TW TW094115936A patent/TW200528419A/zh unknown
- 1999-07-13 TW TW088110752A patent/TWI250141B/zh not_active IP Right Cessation
-
2000
- 2000-12-22 US US09/746,041 patent/US6329552B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HK1035712A1 (en) | 2001-12-07 |
| ID27500A (id) | 2001-04-12 |
| MY117662A (en) | 2004-07-31 |
| BRPI9912208B8 (pt) | 2021-05-25 |
| EP1089961A1 (en) | 2001-04-11 |
| CN1312794A (zh) | 2001-09-12 |
| PE20000703A1 (es) | 2000-08-23 |
| PT1089961E (pt) | 2004-06-30 |
| EP1089961B1 (en) | 2004-02-11 |
| WO1999067197A1 (en) | 1999-12-29 |
| JP2002518467A (ja) | 2002-06-25 |
| TW200528419A (en) | 2005-09-01 |
| CA2335685A1 (en) | 1999-12-29 |
| AU4776399A (en) | 2000-01-10 |
| CO5040050A1 (es) | 2001-05-29 |
| BR9912208A (pt) | 2001-04-10 |
| CA2335685C (en) | 2009-08-11 |
| JP4355450B2 (ja) | 2009-11-04 |
| ATE259346T1 (de) | 2004-02-15 |
| TWI250141B (en) | 2006-03-01 |
| US6329552B2 (en) | 2001-12-11 |
| ES2216528T3 (es) | 2004-10-16 |
| BRPI9912208B1 (pt) | 2016-04-19 |
| US20010014699A1 (en) | 2001-08-16 |
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| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: NOVARTIS CO., LTD. Free format text: FORMER NAME: NOVARTIS AG |
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| CP01 | Change in the name or title of a patent holder |
Address after: Basel Patentee after: Novartis Ag Address before: Basel Patentee before: Novartis AG |
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| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20050105 |