BRPI9912208B8 - compostos orgânicos, seu uso e seu método de preparação, bem como composição farmacêutica - Google Patents

compostos orgânicos, seu uso e seu método de preparação, bem como composição farmacêutica

Info

Publication number
BRPI9912208B8
BRPI9912208B8 BRPI9912208A BR9912208A BRPI9912208B8 BR PI9912208 B8 BRPI9912208 B8 BR PI9912208B8 BR PI9912208 A BRPI9912208 A BR PI9912208A BR 9912208 A BR9912208 A BR 9912208A BR PI9912208 B8 BRPI9912208 B8 BR PI9912208B8
Authority
BR
Brazil
Prior art keywords
preparation
well
pharmaceutical composition
organic compounds
polar substituents
Prior art date
Application number
BRPI9912208A
Other languages
English (en)
Portuguese (pt)
Other versions
BR9912208A (pt
BRPI9912208B1 (pt
Inventor
Allmendinger Thomas
Helmut Wernsdorfer Walther
Original Assignee
Novartis Ag Novartis Sa Novartis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag Novartis Sa Novartis Inc filed Critical Novartis Ag Novartis Sa Novartis Inc
Publication of BR9912208A publication Critical patent/BR9912208A/pt
Publication of BRPI9912208B1 publication Critical patent/BRPI9912208B1/pt
Publication of BRPI9912208B8 publication Critical patent/BRPI9912208B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/38Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings with rings other than six-membered aromatic rings being part of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BRPI9912208A 1998-06-25 1999-06-23 compostos orgânicos, seu uso e seu método de preparação, bem como composição farmacêutica BRPI9912208B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH135198 1998-06-25
PCT/EP1999/004355 WO1999067197A1 (en) 1998-06-25 1999-06-23 Benflumetol derivatives, intermediates thereof and their use against parasitical protozoa and trematodes

Publications (3)

Publication Number Publication Date
BR9912208A BR9912208A (pt) 2001-04-10
BRPI9912208B1 BRPI9912208B1 (pt) 2016-04-19
BRPI9912208B8 true BRPI9912208B8 (pt) 2021-05-25

Family

ID=4208448

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9912208A BRPI9912208B8 (pt) 1998-06-25 1999-06-23 compostos orgânicos, seu uso e seu método de preparação, bem como composição farmacêutica

Country Status (16)

Country Link
US (1) US6329552B2 (https=)
EP (1) EP1089961B1 (https=)
JP (1) JP4355450B2 (https=)
CN (1) CN1183097C (https=)
AT (1) ATE259346T1 (https=)
AU (1) AU4776399A (https=)
BR (1) BRPI9912208B8 (https=)
CA (1) CA2335685C (https=)
CO (1) CO5040050A1 (https=)
ES (1) ES2216528T3 (https=)
ID (1) ID27500A (https=)
MY (1) MY117662A (https=)
PE (1) PE20000703A1 (https=)
PT (1) PT1089961E (https=)
TW (2) TW200528419A (https=)
WO (1) WO1999067197A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104093689A (zh) * 2012-01-31 2014-10-08 剑桥显示技术有限公司 聚合物
CN111320547B (zh) * 2020-04-03 2022-05-20 南京昊绿生物科技有限公司 一种苯芴醇-d9的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1029680C (zh) * 1988-11-10 1995-09-06 军事医学科学院微生物流行病研究所 抗疟新药苯芴醇的合成新工艺
CN1058717A (zh) * 1990-08-08 1992-02-19 中国人民解放军军事医学科学院微生物流行病研究所 抗疟新药—复方蒿甲醚及其制备方法

Also Published As

Publication number Publication date
HK1035712A1 (en) 2001-12-07
ID27500A (id) 2001-04-12
MY117662A (en) 2004-07-31
EP1089961A1 (en) 2001-04-11
CN1312794A (zh) 2001-09-12
PE20000703A1 (es) 2000-08-23
PT1089961E (pt) 2004-06-30
EP1089961B1 (en) 2004-02-11
WO1999067197A1 (en) 1999-12-29
JP2002518467A (ja) 2002-06-25
TW200528419A (en) 2005-09-01
CA2335685A1 (en) 1999-12-29
AU4776399A (en) 2000-01-10
CO5040050A1 (es) 2001-05-29
BR9912208A (pt) 2001-04-10
CN1183097C (zh) 2005-01-05
CA2335685C (en) 2009-08-11
JP4355450B2 (ja) 2009-11-04
ATE259346T1 (de) 2004-02-15
TWI250141B (en) 2006-03-01
US6329552B2 (en) 2001-12-11
ES2216528T3 (es) 2004-10-16
BRPI9912208B1 (pt) 2016-04-19
US20010014699A1 (en) 2001-08-16

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B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10 ( VIII ), 13 E 25 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

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B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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B16C Correction of notification of the grant [chapter 16.3 patent gazette]

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