CN116850099B - Mild and tear-free moisturizing facial cleanser and preparation method thereof - Google Patents
Mild and tear-free moisturizing facial cleanser and preparation method thereof Download PDFInfo
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- CN116850099B CN116850099B CN202310572546.3A CN202310572546A CN116850099B CN 116850099 B CN116850099 B CN 116850099B CN 202310572546 A CN202310572546 A CN 202310572546A CN 116850099 B CN116850099 B CN 116850099B
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- tear
- plant extract
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- 230000001815 facial effect Effects 0.000 title claims abstract description 77
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 46
- 238000002360 preparation method Methods 0.000 title abstract description 8
- 239000000284 extract Substances 0.000 claims abstract description 61
- 239000000419 plant extract Substances 0.000 claims abstract description 61
- 150000001413 amino acids Chemical class 0.000 claims abstract description 32
- 241000717673 Clerodendranthus spicatus Species 0.000 claims abstract description 16
- 241000233855 Orchidaceae Species 0.000 claims abstract description 13
- 229940059958 centella asiatica extract Drugs 0.000 claims abstract description 13
- 238000004140 cleaning Methods 0.000 claims abstract description 12
- 239000004094 surface-active agent Substances 0.000 claims abstract description 10
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 8
- 239000003906 humectant Substances 0.000 claims abstract description 8
- 239000002562 thickening agent Substances 0.000 claims abstract description 8
- 229940106579 hops extract Drugs 0.000 claims abstract description 6
- 239000001906 humulus lupulus l. absolute Substances 0.000 claims abstract description 6
- 239000002888 zwitterionic surfactant Substances 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 24
- 238000002156 mixing Methods 0.000 claims description 21
- 238000003756 stirring Methods 0.000 claims description 20
- 239000007788 liquid Substances 0.000 claims description 16
- 238000001816 cooling Methods 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 11
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 10
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 10
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 10
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical group C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 claims description 8
- ANJTVLIZGCUXLD-BDAKNGLRSA-N (-)-Cytisine Natural products C1NC[C@@H]2CN3C(=O)C=CC=C3[C@H]1C2 ANJTVLIZGCUXLD-BDAKNGLRSA-N 0.000 claims description 8
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- 229920001213 Polysorbate 20 Polymers 0.000 claims description 8
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 8
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 8
- ANJTVLIZGCUXLD-DTWKUNHWSA-N cytisine Chemical compound C1NC[C@H]2CN3C(=O)C=CC=C3[C@@H]1C2 ANJTVLIZGCUXLD-DTWKUNHWSA-N 0.000 claims description 8
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- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 claims description 8
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 4
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- 229930182470 glycoside Natural products 0.000 claims description 4
- WRYLYDPHFGVWKC-SNVBAGLBSA-N 4-Terpineol Natural products CC(C)[C@]1(O)CCC(C)=CC1 WRYLYDPHFGVWKC-SNVBAGLBSA-N 0.000 claims description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
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- FSLPMRQHCOLESF-SFMCKYFRSA-N alpha-amyrin Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C FSLPMRQHCOLESF-SFMCKYFRSA-N 0.000 claims description 3
- SJMCNAVDHDBMLL-UHFFFAOYSA-N alpha-amyrin Natural products CC1CCC2(C)CCC3(C)C(=CCC4C5(C)CCC(O)CC5CCC34C)C2C1C SJMCNAVDHDBMLL-UHFFFAOYSA-N 0.000 claims description 3
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- WYQVAPGDARQUBT-XCWYDTOWSA-N asiaticoside Natural products O=C(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@H](O)[C@H](O)[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](CO)O2)O1)[C@@]12[C@@H]([C@@H](C)[C@H](C)CC1)C=1[C@](C)([C@@]3(C)[C@@H]([C@@]4(C)[C@H]([C@@](CO)(C)[C@@H](O)[C@H](O)C4)CC3)CC=1)CC2 WYQVAPGDARQUBT-XCWYDTOWSA-N 0.000 claims description 3
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- WPVSVIXDXMNGGN-UHFFFAOYSA-N beta-bitter acid Natural products CC(C)CC(=O)C1=C(O)C(CC=C(C)C)(CC=C(C)C)C(=O)C(CC=C(C)C)=C1O WPVSVIXDXMNGGN-UHFFFAOYSA-N 0.000 claims description 3
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- LSDULPZJLTZEFD-UHFFFAOYSA-N lupulone Chemical compound CC(C)CC(=O)C1=C(O)C(CC=C(C)C)=C(O)C(CC=C(C)C)(CC=C(C)C)C1=O LSDULPZJLTZEFD-UHFFFAOYSA-N 0.000 claims description 3
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Abstract
The application particularly discloses a mild tear-free moisturizing facial cleanser and a preparation method thereof. The mild tear-free moisturizing facial cleanser comprises the following raw materials in parts by weight: comprises a plant extract A, a plant extract B, an amino acid surfactant, a zwitterionic surfactant, a humectant, an emulsifying agent, a skin feel regulator, a pH regulator and a thickening agent; wherein the plant extract A is in a weight ratio of (2-3.5): 1, clerodendranthus spicatus extract and hops extract; the plant extract B is prepared from the following components in percentage by weight (3-7): (2-5): 1 centella asiatica extract, broom extract, maastricht Treaty orchid extract. The facial cleanser provided by the application has the advantages of mildness, no stimulation and excellent skin cleaning and nourishing effects.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a mild tear-free moisturizing facial cleanser and a preparation method thereof.
Background
Skin is one of the important organs of the human body, and skin health is also an important sign of human health; the skin surface of the human body is covered by sebum secreted by sebaceous glands to form a natural protective film, so that the skin surface is soft and smooth. However, the health state of the skin can be negatively affected if the human body is not cleaned in time due to the pollution of sweat, dust and other dirt on the face of the human body every day.
With the improvement of the living standard of people, the attention to facial cleaning is also increasing, and the variety of facial cleaning products is also increasing. The facial cleanser is used as one of facial cleaning products, has the effects of cleaning, nourishing, protecting skin and the like, and can remove oil-soluble fat scale and water-soluble dirt of the face by means of similar compatibility principles in the skin care and face washing process. However, in order to improve the skin cleaning capability, the conventional facial cleanser generally has a higher content of soap base, and the soap base can destroy the normal secretion of sebum, so that the skin is alkaline, the natural metabolic capability of the skin is weakened, the skin is rough and sensitive, the skin is stimulated, and the stable state of the sensitive skin and the infant skin is negatively influenced after long-term use.
Accordingly, there is a need to provide a facial cleansing product which is mild, non-irritating, capable of nourishing the skin and excellent in cleansing effect.
Disclosure of Invention
The application provides a mild and tear-free moisturizing type facial cleanser and a preparation method thereof in order to obtain the facial cleanser which is mild and non-irritating and has the effects of cleaning and nourishing skin.
In a first aspect, the application provides a mild tear-free moisturizing type facial cleanser, which adopts the following technical scheme:
A mild and tear-free moisturizing facial cleanser comprises a plant extract A, a plant extract B, an amino acid surfactant, a zwitterionic surfactant, a humectant, an emulsifying agent, a skin feel regulator, a pH regulator and a thickening agent;
Wherein the plant extract A is in a weight ratio of (2-3.5): 1, clerodendranthus spicatus extract and hops extract;
the plant extract B is prepared from the following components in percentage by weight (3-7): (2-5): 1, a asiatic centella extract, a cytisine extract, a Maastricht Treaty orchid extract;
Wherein the clerodendranthus spicatus extract contains alkyl glycoside substances, amide substances and rosmarinic acid components; the hop extract contains flavonol, lupulone, humulone and polyphenol; the centella asiatica extract contains alpha-amyrin alcohol type triterpene, asiaticoside and centella asiatica polysaccharide components; the flos Caraganae Sinicae extract contains chrysoeriol component; the Maastricht Treaty orchid extract contains 4-terpineol component.
Firstly, alkyl glycoside components contained in the clerodendranthus spicatus extract have no irritation to skin, have a surface Zhang Lidi, good solubility, strong detergency, high-concentration electrolyte resistance and high alkali resistance, have good thickening effect and compatibility, and can be compounded with amino acid surfactants and zwitterionic surfactants to generate synergistic effect, so that the mildness and the detergency of a formula are obviously improved; moreover, the hop extract can act together with alkyl glycoside components, so that the cleaning capability of the facial cleanser is further improved, and the sensitive damage to human skin caused by the over-strong cleaning capability is reduced. Secondly, amide substances in the clerodendranthus spicatus extract can inhibit the generation of TNF-alpha, reduce the inhibition of TNF-alpha on proliferation and migration of fibroblasts, enable the fibroblasts to secrete a large amount of matrix proteins forming a skin matrix, and keep the elasticity and structure of the skin; finally, rosmarinic acid in the clerodendranthus spicatus extract can act together with flavonol in the hop extract, so that the metabolism capability of human skin is remarkably improved, the skin is nourished, and the clerodendranthus spicatus extract has excellent moisturizing performance on the human skin, so that a barrier protection function can be established, and the stability of the health state of the clerodendranthus spicatus extract is improved.
In addition, on the one hand, the alpha-amyrin alcohol type triterpene component in the centella asiatica extract can act together with the cytisine extract to calm the skin and improve the expression of elastin genes and lAMA genes, so that the attachment of cells to a matrix is promoted, the skin elasticity is improved, and the skin surface layer, the basal membrane layer and the dermis layer can smoothly circulate, so that the healthy integrity of the skin is maintained; on the other hand, asiaticoside in herba Centellae extract can co-act with 4-terpineol in Maastricht Treaty orchid extract, promote cytokine expression and inhibit protein expression in fibroblast, and promote facial skin blood circulation and skin metabolism while stimulating nutrition epidermis or dermis stem cell, thereby increasing skin elasticity and glossiness; the three components cooperate to realize the repairing function of the skin, stabilize the skin structure, strengthen and maintain the skin elasticity, improve the epidermis barrier capability of the skin, increase the skin moisture and nourish the skin.
And secondly, the synergistic interaction between the plant extracts A and B can be fully exerted to obtain the facial cleanser with no irritation to skin, good cleaning effect and excellent nutrition effect, and the facial cleanser helps the skin to establish a good protective barrier.
Finally, lupulone, humulone and polyphenol in the hop extract and centella polysaccharide in the centella extract have excellent inhibitory activity on fungi and bacteria, and have high safety on sensitive skin and infant skin, and the two extracts act together as a plant source preservative, so that the antibacterial performance and the safety performance of the facial cleanser can be further improved.
Optionally, the facial cleanser comprises, by weight, 0.5-4 parts of a plant extract A, 0.3-1.5 parts of a plant extract B, 20-35 parts of an amino acid surfactant, 10-25 parts of a zwitterionic surfactant, 8-15 parts of a humectant, 0.1-0.3 part of an emulsifying agent, 0.5-3 parts of a skin feel regulator, 0.2-0.5 part of a pH regulator and 0.5-2 parts of a thickening agent.
Optionally, the facial cleanser further comprises a mycosporine-like amino acid.
The mycosporine-like amino acid has an annular structure skeleton containing aminocyclohexenone or aminocyclohexylamine, has excellent oxidation resistance and moisturizing effect, can be matched with a plant extract B in a synergistic way, remarkably improves the moisturizing effect of the facial cleanser on skin, enables the skin to establish an excellent protective barrier, and maintains the health stability of sensitive skin and infant skin.
Optionally, the mycosporine-like amino acid is extracted from any one of raw materials selected from agar or red Mao Tai.
Optionally, the mycosporine-like amino acid is extracted from the agar or the red moss by using methanol as a solvent.
Optionally, the concentration of the methanol solvent is 20wt% to 25wt%.
By extracting the mycosporine-like amino acid from the two raw materials, the mycosporine-like Bao Su amino acid with the most excellent compatibility with the plant extract B is obtained, and the nutrition effect of the facial cleanser on the skin is improved to the greatest extent.
Optionally, the mass ratio of the mycosporine-like amino acid to the plant extract B is (1-2.5): 1.
Optionally, the mass ratio of the mycosporine-like amino acid to the plant extract B is (1.5-2): 1.
The dosage of the mycosporine-like amino acid and the plant extract B is controlled, so that the synergistic effect of the mycosporine-like amino acid, the centella asiatica extract, the cytisine extract and the Maastricht Treaty orchid extract can be exerted to the greatest extent, and the health state of the skin is obviously improved.
Optionally, the amino acid surfactant is at least one selected from sodium lauroyl sarcosinate, sodium cocoyl aminopropionate and sodium lauroyl glutamate.
Optionally, the zwitterionic surfactant is at least one of lecithin and cocamidopropyl betaine.
By selecting a proper surfactant, the irritation of the cleanser to sensitive skin and infant skin can be reduced when the cleanser is used for a long time while the cleansing ability of the cleanser is improved.
Optionally, the humectant is at least one of glycerin, sodium hyaluronate and propylene glycol; the emulsifier is polysorbate-20; the skin feel modifier is polyquaternium-7; the pH regulator is citric acid; the thickener is 1, 3-propanediol.
In a second aspect, the application provides a method for preparing mild tear-free moisturizing facial cleanser, which adopts the following technical scheme:
a preparation method of mild tear-free moisturizing facial cleanser comprises the following steps:
Step one, mixing the surfactant, the humectant and the emulsifier, heating at 60-70 ℃ for heat preservation, and stirring to obtain mixed liquid;
Step two, cooling the mixed liquid to 40-50 ℃, and then mixing and stirring the mixed liquid with the skin feel regulator, the pH regulator and the thickener to obtain a mixed system;
step three, continuously heating the mixed system to 60-70 ℃, and mixing and stirring the mixed system with the plant extract A to obtain a premix;
And fourthly, cooling the premix to 45-55 ℃, mixing and stirring the premix and the plant extract B, and continuing cooling to obtain the mild tear-free moisturizing facial cleanser.
Detailed Description
For a better understanding and implementation, the technical solutions of the present invention will be clearly and completely described below in connection with examples.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.
Unless otherwise indicated, all numbers expressing quantities of ingredients, reaction conditions, and so forth used in the specification and claims are to be understood as being modified in all instances by the term "about". Accordingly, unless indicated to the contrary, the numerical parameters set forth herein are approximations that may vary depending upon the desired properties to be obtained.
As used herein, "and/or" means one or all of the elements mentioned.
The use of "including" and "comprising" herein encompasses both the situation in which only the elements are mentioned and the situation in which other elements not mentioned are present in addition to the elements mentioned.
All percentages in the present invention are by weight unless otherwise indicated.
As used in this specification, the terms "a," "an," "the," and "the" are intended to include "at least one" or "one or more," unless otherwise specified. For example, "a component" refers to one or more components, and thus more than one component may be considered and possibly employed or used in the practice of the embodiments.
Examples
Example 1
A mild tear-free moisturizing facial cleanser comprises the following components in parts by weight:
2g of plant extract A: wherein the weight ratio of clerodendranthus spicatus extract to hop extract is 3:1,0.9g of plant extract B: wherein the weight ratio of centella asiatica extract to cytisine extract to Maastricht Treaty orchid extract is 3:5:1, 30g of sodium lauroyl sarcosinate, 15g of cocamidopropyl betaine, 12g of sodium hyaluronate, 0.2g of polysorbate-20, 2g of polyquaternium-7, 0.3g of citric acid and 1g of 1, 3-propanediol.
A mild and tear-free moisturizing facial cleanser is prepared by the following steps:
step one, mixing sodium lauroyl sarcosinate, cocamidopropyl betaine, sodium hyaluronate and polysorbate-20, heating at 65 ℃ for preserving heat and stirring for 25min to obtain mixed liquid;
step two, cooling the mixed liquid to 45 ℃, and then mixing the mixed liquid with polyquaternium-7, citric acid and 1, 3-propanediol and stirring for 10min to obtain a mixed system;
step three, continuously heating the mixed system to 65 ℃, and mixing and stirring the mixed system with the plant extract A to obtain a premix;
And fourthly, cooling the premix to 50 ℃, mixing with the plant extract B, stirring for 7min, and continuously cooling to 35 ℃ to obtain the mild and tear-free moisturizing facial cleanser.
Example 2
A mild tear-free moisturizing facial cleanser comprises the following components in parts by weight:
0.5g of plant extract A: wherein the weight ratio of clerodendranthus spicatus extract to hop extract is 3.5:1,1.5g of plant extract B: wherein the weight ratio of centella asiatica extract to cytisine extract to Maastricht Treaty orchid extract is 5:3:1, 20g of sodium lauroyl sarcosinate, 25g of cocamidopropyl betaine, 8g of sodium hyaluronate, 0.1g of polysorbate-20, 3g of polyquaternium-7, 0.5g of citric acid and 0.5g of 1, 3-propanediol.
A mild and tear-free moisturizing facial cleanser is prepared by the following steps:
Step one, mixing sodium lauroyl sarcosinate, cocamidopropyl betaine, sodium hyaluronate and polysorbate-20, heating at 60 ℃ for heat preservation, and stirring for 30min to obtain mixed liquid;
Step two, cooling the mixed liquid to 50 ℃, and then mixing the mixed liquid with polyquaternium-7, citric acid and 1, 3-propanediol and stirring for 5min to obtain a mixed system;
Step three, continuously heating the mixed system to 60 ℃, and mixing and stirring the mixed system with the plant extract A to obtain a premix;
and fourthly, cooling the premix to 45 ℃, mixing with the plant extract B, stirring for 10min, and continuously cooling to 30 ℃ to obtain the mild and tear-free moisturizing facial cleanser.
Example 3
A mild tear-free moisturizing facial cleanser comprises the following components in parts by weight:
4g of plant extract A: the weight ratio of clerodendranthus spicatus extract to hop extract is 2:1,0.3g of plant extract B: the weight ratio of centella asiatica extract to cytisine extract to Maastricht Treaty orchid extract is 7:2:1, 35g of sodium lauroyl sarcosinate, 10g of cocamidopropyl betaine, 15g of sodium hyaluronate, 0.3g of polysorbate-20, 3g of polyquaternium-7, 0.2g of citric acid and 2g of 1, 3-propanediol.
A mild and tear-free moisturizing facial cleanser is prepared by the following steps:
step one, mixing sodium lauroyl sarcosinate, cocamidopropyl betaine, sodium hyaluronate and polysorbate-20, heating at 70 ℃, preserving heat and stirring for 20min to obtain a mixed liquid;
step two, cooling the mixed liquid to 40 ℃, and then mixing the mixed liquid with polyquaternium-7, citric acid and 1, 3-propanediol and stirring for 15min to obtain a mixed system;
step three, continuously heating the mixed system to 70 ℃, and mixing and stirring the mixed system with the plant extract A to obtain a premix;
And fourthly, cooling the premix to 55 ℃, mixing with the plant extract B, stirring for 5min, and continuously cooling to 40 ℃ to obtain the mild and tear-free moisturizing facial cleanser.
Example 4
The mild tear-free moisturizing type facial cleanser is different from the embodiment 1 in that the facial cleanser also comprises a mycosporine-like amino acid extracted from the agar by taking 20wt% of methanol as a solvent, and the mass ratio of the mycosporine-like amino acid to the plant extract B is 1:1.
Example 5
The mild tear-free moisturizing type facial cleanser is different from the embodiment 1 in that the facial cleanser also comprises a mycosporine-like amino acid extracted from the red moss by taking 25 weight percent of methanol as a solvent, and the mass ratio of the mycosporine-like amino acid to the plant extract B is 2.5:1.
Example 6
The mild tear-free moisturizing type facial cleanser is different from the embodiment 1 in that the facial cleanser also comprises a mycosporine-like amino acid extracted from the agar by taking 22 weight percent of methanol as a solvent, and the mass ratio of the mycosporine-like amino acid to the plant extract B is 1.5:1.
Example 7
The mild tear-free moisturizing type facial cleanser is different from the embodiment 1 in that the facial cleanser also comprises a mycosporine-like amino acid extracted from the red moss by taking 22 weight percent of methanol as a solvent, and the mass ratio of the mycosporine-like amino acid to the plant extract B is 2:1.
Example 8
The mild tear-free moisturizing type facial cleanser is different from the embodiment 1 in that the facial cleanser also comprises the mycosporine-like amino acid extracted from the gloiopeltis alga by taking 22 weight percent of methanol as a solvent, and the mass ratio of the mycosporine-like amino acid to the plant extract B is 1.5:1.
Comparative example 9
A mild tear-free moisturizing facial cleanser, which is different from example 1 in that the facial cleanser also comprises sodium hyaluronate, and the mass ratio of the sodium hyaluronate to the plant extract B is 1.5:1.
Comparative example
Comparative example 1
A mild, tear-free moisturizing facial cleanser, which differs from example 1 in that no plant extract a is used in the preparation of the facial cleanser.
Comparative example 2
A mild, tear-free moisturizing facial cleanser, which differs from example 1 in that no plant extract B was used in the preparation of the facial cleanser.
Comparative example 3
The mild tear-free moisturizing facial cleanser is different from example 1 in that in the process of preparing the facial cleanser, the weight ratio of clerodendranthus spicatus extract to hop extract in plant extract A is 0.5:1, and the weight ratio of centella asiatica extract, broom extract and Maastricht Treaty orchid extract in plant extract B is 1:8:1.
Comparative example 4
The mild tear-free moisturizing facial cleanser is different from example 1 in that in the process of preparing the facial cleanser, the weight ratio of clerodendranthus spicatus extract to hop extract in plant extract A is 5:1, and the weight ratio of centella asiatica extract, broom extract and Maastricht Treaty orchid extract in plant extract B is 10:0.5:1.
Comparative example 5
A mild, tear-free moisturizing facial cleanser, which differs from example 1 in that in the process of preparing the facial cleanser, the hops extract in plant extract a is replaced with an equivalent weight of clove extract.
Comparative example 6
A mild tear-free moisturizing facial cleanser, which is different from example 1 in that centella asiatica extract in plant extract B is replaced with an equal weight of saussurea involucrata extract in the process of preparing the facial cleanser.
Comparative example 7
A mild, tear-free moisturizing facial cleanser, which is different from example 1 in that a commercially available tear-free facial cleanser was used.
Detection method
1. Irritation test
1. PH value test
The pH value of the cleansing emulsions prepared in examples 1 to 9 and comparative examples 1 to 7 was measured according to the general test method for cosmetics of GB/T13531.1-2008, and the measured pH values were recorded in table 2.
2. Skin irritation test
The prepared face washes of examples 1 to 9 and comparative examples 1 to 7 were tested according to SNT2329-2009 cosmetic eye irritation/corrosiveness chick embryo appearance allantoic membrane test standard issued by the industry standard of entry and exit inspection and quarantine of the people's republic of China, and the irritation ability of the samples was examined. The test method comprises the following steps: checking 9-day-old chick embryos by egg irradiation, and marking the positions of air chambers on the surfaces of shells; a small hole was drilled in the air chamber Fang Xiaoxin with a punch and the dental curved forceps peeled off the marked eggshell portion exposing the white film. After the egg membrane is wetted by sucking a proper amount of NaCl solution with the mass fraction of 0.9% by using a suction tube, the solution is poured out. The intima was carefully removed with forceps, ensuring that the vessel was not damaged. If the test object is transparent liquid, the time reaction experiment method is adopted. Respectively sucking 0.3mL of the tested agent, dripping the tested agent on the surface of chorioallantoic membrane, recording the change condition of blood vessels within 5min, observing the time of bleeding, thawing and coagulation of the blood vessels, and taking photos and recording images. Calculating the stimulation score IS value according to the formula, carrying out parallel experiments on each sample, calculating the average time of bleeding, blood melting and blood coagulation, and calculating the average IS value according to the formula:
IS=(301-secH)×5/300+(301-secL)×7/300+(301-secC)×9/300
Wherein secH (time to bleed) -the average time in s at which bleeding starts to occur is observed on the CAM film; secL (vascular thawing time) -average time in s at which onset of vascular thawing is observed on the CAM membrane; secC (clotting time) -the average time in s at which clotting begins to occur is observed on the CAM membrane.
Bleeding: blood flows from the blood vessels and/or capillaries of the CAM in a variety of manifestations such as cauliflower, smooth dispersion, or bleeding-on-demand.
Coagulation: denaturation of in-and out-tube proteins is usually seen only in large and moderately large blood vessels, excluding changes in capillary angiogenesis.
Vascular thawing: the disappearance of the blood vessels on the CAM membrane may be due to multiple factors such as bleeding, wall tension, etc.
Test article: the products in each example of the present invention were diluted to 1% by mass and evaluated by the reaction time method (stimulus evaluation method). Two control groups were additionally provided, one group being physiological saline with a mass fraction of 0.9% and the other group being K12 (sodium dodecyl sulfate) with a mass fraction of 1%. The number of the test chick embryos in the control group and the number of the test chick embryos in each example group are 6 respectively.
Results of the stimulation scoring are shown in table 1, and results of the test object of the present invention are shown in table 2:
TABLE 1
TABLE 2
2. Cleaning ability test
The cleansing ability test was conducted on the cleansing emulsions prepared in examples 1 to 9 and comparative examples 1 to 7, and the test method was specifically as follows: selecting 50 experienced skin-sensitive volunteers for testing, continuously using the facial cleanser for one week during testing, scoring according to sensory experience of a user, and taking an average value for settlement, wherein the time is 2 times per day; the scoring was performed using a10 point scale, and the scores were recorded in table 3, with respect to five aspects of skin irritation, greasy feel, smoothness, comfort, and tightness.
TABLE 3 Table 3
3. Transdermal water loss rate test
The skin of the above 50 skin-sensitive volunteers using a cleanser was subjected to a transdermal water loss rate test as follows: using mountingThe percutaneous water loss value was measured by a noninvasive skin detector (Courage & Khazak, germany) of the TM300 probe; the open cavity method is used, the shorter side of the probe is lightly and vertically attached to the skin surface of the test point, a handle red button is pressed, measurement is started, a display screen displays each s of numerical value, a 30s system is automatically stopped, and the screen displays the measurement result; and the test results are recorded in table 4.
4. Skin stratum corneum moisture content test
The skin of the above 50 skin-sensitive volunteers using a cleanser was subjected to a horny layer moisture content test as follows: using mountingThe non-invasive skin detector (Courage & Khazak, germany) of the CM825 probe measures the moisture content of the skin stratum corneum, the test probe is vertically placed on the skin surface of the test point, the probe is lightly pressed by force, and the screen displays the measurement result after the probe is loosened to rebound. Repeating the test for three times at each part, and taking an average value; and the test results are recorded in table 4.
TABLE 4 Table 4
Transdermal water loss rate/(g.hm -2) | Moisture content of skin stratum corneum/(au) | |
Example 1 | 7.8 | 55.8 |
Example 2 | 7.7 | 55.1 |
Example 3 | 7.9 | 55.5 |
Example 4 | 7.3 | 56.8 |
Example 5 | 7.1 | 56.9 |
Example 6 | 7.0 | 57.1 |
Example 7 | 7.0 | 57.2 |
Example 8 | 7.8 | 55.3 |
Example 9 | 8.2 | 54.3 |
Comparative example 1 | 9.5 | 50.3 |
Comparative example 2 | 9.3 | 50.5 |
Comparative example 3 | 8.6 | 52.3 |
Comparative example 4 | 8.8 | 52.5 |
Comparative example 5 | 9.2 | 51.4 |
Comparative example 6 | 9.1 | 51.6 |
Comparative example 7 | 10.5 | 47.6 |
In combination with examples 1 to 3, comparative examples 1 to 4 and tables 1 to 4, it can be seen that, first, by using the plant extract a and the plant extract B in the facial cleanser in combination, the cleansing ability of the facial cleanser can be remarkably improved, the pH value of the facial cleanser can be reduced, the irritation to the skin can be reduced, and a natural protective barrier can be formed on the skin surface, so that the skin can be subjected to lower percutaneous moisture loss and higher stratum corneum moisture content, and the healthy and stable state of the skin can be improved. Secondly, only the mass ratio of clerodendranthus spicatus extract to hops extract in the plant extract A is controlled to be (2-3.5), 1 and the mass ratio of centella asiatica extract, cytisine extract and Maastricht Treaty orchid extract in the plant extract B is controlled to be (3-7): (2-5): 1, the blending effect of the plant extract A and the plant extract B can be most remarkably exerted.
In combination with example 1, comparative examples 5 to 6 and tables 1 to 4, it can be seen that when using an equal weight of clove extract instead of hops extract or an equal weight of saussurea involucrata extract instead of centella asiatica extract, although both of the alternative substances and the substituted substances have the effect of overlapping in functional use with the substituted substances, they do not exert excellent synergistic effects together with other ingredients in the plant extracts, and thus, the cleansing milk exhibits enhanced irritation, lowered cleansing ability and reduced nutrition barrier function to the skin, negatively affecting the stable state of the human skin.
In combination with example 1, comparative example 7 and tables 1 to 4, it can be seen that the facial cleanser in this embodiment has excellent mildness, strong cleansing power and is capable of nourishing the skin, and the human skin is brought into a stable and healthy state, compared with the commercial facial cleanser.
By combining example 1, examples 4-8 and tables 1-4, it can be seen that by adding a proper amount of the mycosporine-like amino acid extracted from agar or red moss to the cleanser, the moisturizing effect of the cleanser on the skin can be remarkably improved by being cooperated with the plant extract B, so that the skin can establish an excellent protective barrier.
In combination with examples 1, 9 and tables 1 to 4, it can be seen that the retinoid itself has moisturizing effect, but not any one of the ingredients having moisturizing effect can cooperate with the components of the plant extract B after application to the cleanser of the present application to enhance the nutritional effect on sensitive skin.
The present embodiment is only for explanation of the present application and is not to be construed as limiting the present application, and modifications to the present embodiment, which may not creatively contribute to the present application as required by those skilled in the art after reading the present specification, are all protected by patent laws within the scope of claims of the present application.
Claims (6)
1. A mild and tear-free moisturizing facial cleanser, which is characterized in that: the face cleaning emulsion comprises, by weight, 0.5-4 parts of a plant extract A, 0.3-1.5 parts of a plant extract B, 20-35 parts of an amino acid surfactant, 10-25 parts of a zwitterionic surfactant, 8-15 parts of a humectant, 0.1-0.3 part of an emulsifying agent, 0.5-3 parts of a skin feel regulator, 0.2-0.5 part of a pH regulator and 0.5-2 parts of a thickening agent;
Wherein the plant extract A is in a weight ratio of (2-3.5): 1, clerodendranthus spicatus extract and hops extract;
the plant extract B is prepared from the following components in percentage by weight (3-7): (2-5): 1, a asiatic centella extract, a cytisine extract, a Maastricht Treaty orchid extract;
Wherein the clerodendranthus spicatus extract contains alkyl glycoside substances, amide substances and rosmarinic acid components; the hop extract contains flavonol, lupulone, humulone and polyphenol; the centella asiatica extract contains alpha-amyrin alcohol type triterpene, asiaticoside and centella asiatica polysaccharide components; the flos Caraganae Sinicae extract contains chrysoeriol component; the Maastricht Treaty orchid extract contains 4-terpineol component;
Wherein the amino acid surfactant is at least one selected from sodium lauroyl sarcosinate, sodium cocoyl aminopropionate and sodium lauroyl glutamate; the amphoteric surfactant is at least one of lecithin and cocamidopropyl betaine; the emulsifier is polysorbate-20; the skin feel modifier is polyquaternium-7; the humectant is at least one of glycerin, sodium hyaluronate and propylene glycol;
Wherein the facial cleanser also comprises mycosporine-like amino acid.
2. The mild tear-free moisturizing facial cleanser of claim 1, wherein: the mycosporine-like amino acid is extracted from any one of raw materials selected from agar or red Mao Tai.
3. The mild tear-free moisturizing facial cleanser of claim 1, wherein: the mass ratio of the mycosporine-like amino acid to the plant extract B is (1-2.5): 1.
4. A mild tear-free moisturizing facial cleanser according to claim 3, wherein: the mass ratio of the mycosporine-like amino acid to the plant extract B is (1.5-2): 1.
5. The mild tear-free moisturizing facial cleanser of claim 1, wherein: the pH regulator is citric acid; the thickener is 1, 3-propanediol.
6. The method for preparing mild tear-free moisturizing facial cleanser according to any one of claims 1 to 5, which is characterized in that: the method comprises the following steps:
Step one, mixing the surfactant, the humectant and the emulsifier, heating at 60-70 ℃ for heat preservation, and stirring to obtain mixed liquid;
Step two, cooling the mixed liquid to 40-50 ℃, and then mixing and stirring the mixed liquid with the skin feel regulator, the pH regulator and the thickener to obtain a mixed system;
step three, continuously heating the mixed system to 60-70 ℃, and mixing and stirring the mixed system with the plant extract A to obtain a premix;
And fourthly, cooling the premix to 45-55 ℃, mixing and stirring the premix and the plant extract B, and continuing cooling to obtain the mild tear-free moisturizing facial cleanser.
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CN107362078A (en) * | 2017-06-28 | 2017-11-21 | 权启康 | A kind of Chinese herbal medicine toner |
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