CN116251042A

CN116251042A - Plant composition with anti-aging effect

Info

Publication number: CN116251042A
Application number: CN202111453755.3A
Authority: CN
Inventors: 请求不公布姓名
Original assignee: Guangzhou Yuan Henry Zhen Cosmetics Co ltd
Current assignee: Guangzhou Yuan Henry Zhen Cosmetics Co ltd
Priority date: 2021-12-01
Filing date: 2021-12-01
Publication date: 2023-06-13

Abstract

The invention relates to the technical field of cosmetics, and discloses a plant composition with an anti-aging effect, which comprises the following components in percentage by weight: 1-20% of snow lotus herb extract, 1-20% of grape seed extract, 1-20% of evening primrose extract, 1-20% of chamomile extract, 40-60% of polyalcohol and the balance of water; the composition is rich in active substances such as flavonoids, phenols and the like, and can remove peroxidation free radicals, improve the self-repairing capability of damaged DNA cells, improve the activity of oxidized lipid enzyme, promote microcirculation, inhibit inflammatory factors and the like, thereby achieving the anti-aging purpose. The composition of the invention is natural, safe and non-irritating, can be used for preparing anti-aging cosmetics, and has the effects of tightening skin and reducing fine wrinkles.

Description

Plant composition with anti-aging effect

Technical Field

The invention relates to the technical field of cosmetics, in particular to a plant composition with an anti-aging effect.

Background

Aging refers to progressive functional and organic degenerative changes of an organism over time. Skin also ages gradually with age, and there are a series of biological changes during natural aging of skin, such as reduction of cellular components of skin and subcutaneous tissue and changes in immune system, which are mainly manifested by wrinkles, dark complexion, thinning of skin barrier, etc. In particular, it can be divided into natural aging and photoaging. Modern medicine mainly has free radical theory on the cause of aging mechanisms.

Free radicals are strong oxidants that attack unsaturated fatty acids in biological, mitochondrial and microsomal membranes, causing destruction of cell membranes or intracellular microstructures. At the same time, the DNA molecule may be damaged, resulting in bond cleavage, cell death or mutation. The reduced numbers of epidermal and dermal cells, slow down cell proliferation and turnover, and reduce the ability of cellular DNA, proteins, collagen and elastic fibers to synthesize, resulting in skin damage. Therefore, scavenging peroxidized radicals in the body is one of the main methods of anti-aging.

With the continuous improvement of skin care consciousness of people, the anti-aging and anti-aging functions are paid more attention to. The main anti-aging functional components in the market at present are mainly used for promoting collagen and elastin synthesis, mainly used for sod, vitamin e and vitamin c, mainly used for resisting oxidization, mainly used for skin moisturizing and repairing barrier, mainly used for ceramide, hyaluronic acid and lactic acid, mainly used for promoting collagen and elastin synthesis, mainly used for absorbing and shielding ultraviolet rays, and added with sun-screening raw materials. In addition, the common anti-aging products on the market at present mainly comprise synthetic chemical components, and have anti-aging effects, but have great skin irritation and can damage skin barriers to different degrees after long-term use.

Disclosure of Invention

(one) solving the technical problems

Aiming at the defects of the prior art, the invention provides a plant composition with anti-aging effect, and solves the problems in the prior art.

(II) technical scheme

In order to achieve the above purpose, the present invention provides the following technical solutions: a plant composition with anti-aging effect comprises the following components in percentage by weight: 1-20% of snow lotus herb extract, 1-20% of grape seed extract, 1-20% of evening primrose extract, 1-20% of chamomile extract, 40-60% of polyalcohol and the balance of water.

Preferably, the composition comprises the following components in percentage by weight: 1-20% of snow lotus herb extract, 1-10% of grape seed extract, 1-5% of evening primrose extract, 1-5% of chamomile extract, 50-60% of polyalcohol and the balance of water.

Preferably, the polyol is butanediol.

The saussurea involucrata extract contains rich flavonoid substances, and the saussurea involucrata grows in mountain areas with low-temperature hypoxia and strong ultraviolet rays, has good stress resistance, has more flavonoid components than flavonoid in common plants, has stronger efficacy, and can block the chain reaction of peroxidation free radicals. Grape seed extract contains abundant anthocyanin, has oxidation resistance in plant, can remove free radical in large amount, and has good synergistic effect with herba Saussureae Involueratae extract. The evening primrose contains abundant unsaturated fatty acid, and can improve skin microcirculation and relieve skin inflammation caused by free radical attack. The chamomile extract contains bisabolol, has good effect of relieving sensitive skin, and has inhibiting effect on skin inflammatory factor caused by free radicals.

Preferably, the composition is prepared as follows: mixing 1-20 parts of herba Saussureae Involueratae extract, 1-20 parts of grape seed extract, 1-20 parts of evening primrose extract and 1-20 parts of flos Matricariae Chamomillae extract, adding 40-60 parts of polyalcohol, and balancing water to obtain the composition with antiaging effect.

Preferably, the main functional components of the saussurea involucrata extract are flavonoids, and the purity ratio is 1-10%.

Preferably, the main functional component of the grape seed extract is anthocyanin opc, and the purity ratio is 95-99%.

Preferably, the main effective component of the evening primrose extract is linoleic acid, and the purity ratio is 1-17%.

Preferably, the main effective component of the chamomile extract is alpha-bisabolol, and the purity ratio is 1-10%.

Preferably, the composition with anti-aging function is added into cosmetics as an anti-aging component, wherein the addition amount of the composition with anti-aging function accounts for 1% -20% of the quality of the cosmetics.

The specific application method of the composition in cosmetic workers comprises the following steps:

(1) Adding the emulsifying agent, 16/18 alcohol and vegetable oil into an oil phase pot, heating to 70-85 ℃, and preserving heat for later use after all components are melted;

(2) Adding glycerol, 1, 3-propylene glycol, xanthan gum, sodium hyaluronate and water into an emulsifying pot, heating to 70-85 ℃, and preserving heat for 15-30 minutes;

(3) Pumping the oil phase in the step (1) into the emulsifying pot in the step (2), homogenizing (homogenizing stirring speed is 3000 rpm) for 3-15 minutes, and then preserving heat and stirring (stirring speed is 30 rpm) for 15-45 minutes;

(4) Circularly homogenizing for 8-9 times by a high-pressure homogenizer under the pressure of 102-108 MPa and the temperature of 81-82 ℃, and controlling the outlet temperature of the homogenizer to be lower than 85 ℃ to obtain microemulsion with the particle size of less than 100 nm;

(5) Cooling the emulsion in the step (4) to 40-45 ℃, adding the anti-aging plant extract and the preservative component, and uniformly stirring.

The formulation of the composition applied to cosmetics is in the form of solution, gel, emulsion or cream, and common skin care products comprise facial masks, essence, emulsion, face cream, body milk, hand cream and the like.

(III) beneficial effects

The invention provides a plant composition with anti-aging effect, which has the following beneficial effects:

the composition is rich in active substances such as flavonoids, phenols and the like, and can remove peroxidation free radicals, improve the self-repairing capability of damaged DNA cells, improve the activity of oxidized lipid enzyme, promote microcirculation, inhibit inflammatory factors and the like, thereby achieving the anti-aging purpose. The composition of the invention is natural, safe and non-irritating, can be used for preparing anti-aging cosmetics, and has the effects of tightening skin and reducing fine wrinkles.

Drawings

FIG. 1 is a graph showing the dpph clearance of water-soluble vitamin e, example 1, control 2 and control 3.

Detailed Description

The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

The invention provides a plant composition with anti-aging effect, which comprises active substances such as flavonoids, phenols and the like, wherein the anti-aging effect consists of a snow lotus herb extract, a grape seed extract, a evening primrose extract and a chamomile extract.

Further, the mass ratio of the snow lotus herb extract, the grape seed extract, the evening primrose extract and the chamomile extract is 1-20:1-20:1-20:1-20.

Example 1

A composition (a) with anti-aging function is prepared from the following components in percentage by weight: 10% of saussurea involucrata extract, 6% of grape seed extract, 2% of evening primrose extract, 2% of chamomile extract, 50% of butanediol and 30% of water.

Example 2

A composition (b) with anti-aging function is prepared from the following components in percentage by weight: 10% of saussurea involucrata extract, 5% of grape seed extract, 3% of evening primrose extract, 2% of chamomile extract, 50% of butanediol and 30% of water.

Example 3

A composition (c) with anti-aging function is prepared from the following components in percentage by weight: 15% of saussurea involucrata extract, 3% of grape seed extract, 1% of evening primrose extract, 1% of chamomile extract, 50% of butanediol and 30% of water.

Example 4

A composition (d) with anti-aging function is prepared from the following components in percentage by weight: 5% of saussurea involucrata extract, 5% of grape seed extract, 2% of evening primrose extract, 2% of chamomile extract, 50% of butanediol and 41% of water.

Comparative example 1

A composition (e) with antiaging effect, as in example 1, contains no herba Saussureae Involueratae extract.

Comparative example 2

A composition (f) with anti-aging function, as in example 1, does not contain grape seed extract.

Comparative example 3

A composition (g) with anti-aging function, such as example 1, does not contain evening primrose extract.

Comparative example 4

A composition (h) with anti-aging function, as in example 1, is free of chamomile extract.

Experimental example 1 evaluation of radical scavenging Effect

In the cosmetic field, the anti-aging performance is generally characterized by a dpph free radical scavenging capability test, which is based on the following principle:

dpph (1, 1-dipheny1-2-picrylhydrazyl radical) is a 1, 1-diphenyl-2-picrylhydrazyl radical. In the molecule, nitrogen radicals can exist stably because of the presence of a plurality of electron-withdrawing-NO 2 and a large pi bond of the benzene ring.

As DPPH radicals are scavenged, the absorbance A at 519nm of their absorption maxima decreases. The capacity is expressed by the clearance rate, and the larger the clearance rate is, the stronger the anti-aging capacity is.

The calculation formula of the clearance (inhibition) is as follows:

1. preparation of DPPH test solution

1.0mg of DPPH powder is taken and dissolved in 20mL of 95% ethanol solvent, and the solution is subjected to ultrasonic treatment for 5min and fully and uniformly shaken. Taking 1mL of the DPPH solution, measuring an A value at 519nm, and preserving the solution in a dark place, wherein A=1.2;

2. measurement of

Measurement of A0 value: adding 2mL of DPPH solution into a small test tube, adding 1mL of 95% ethanol, fully mixing, and measuring the A value (519 nm) to obtain the A0 value; measurement of a value: adding 2mL of DPPH solution into a small test tube, adding x mu L of sample solution (x is the maximum use amount of a predicted sample, and 8 use amounts are set forward), adding (1000-x) mu L of 95% ethanol, mixing, standing for 30 minutes, and measuring an A value (519 nm);

3. the positive control (water-soluble vitamin E), example 1, comparative example 2 and comparative example 3 were each tested for antioxidant capacity, and the average clearance was measured three times in parallel, and as shown in fig. 1, the test results of fig. 1 revealed that example 1 had excellent antioxidant capacity and the antioxidant capacity was superior to that of comparative example.

Experimental example 2 plant extracts were added to the following emulsions, respectively

1. Adding the phase a raw material into an oil pot, stirring and heating to 80-85 ℃, and preserving heat for later use.

Adding deionized water into a water pot, stirring, slowly adding carbomer 940, heating after adding carbomer 940, dispersing uniformly, adding b phase of other raw materials, heating to 80-85 deg.C, and maintaining for 30 min.

Filtering the raw material of the phase b by a 200-mesh screen, pumping the raw material into an emulsifying pot, starting stirring, filtering the phase a by the 200-mesh screen, adding the filtered raw material into the phase b, and homogenizing and emulsifying for 8-10 minutes after pumping.

Slowly cooling after homogenizing and emulsifying, adding naoh below 45 deg. and neutralizing.

And (5) adding the rest materials of the phase c below 40 ℃ respectively, and stirring uniformly.

Sampling and detecting, and discharging after the detection is qualified.

Sampling, checking and aging for 24 hours.

And (5) sub-packaging after the inspection is qualified.

2. Volunteers between 25 and 60 years of age were selected for facial skin efficacy testing experiments including skin moisture content experiments, wrinkle mitigation experiments, and skin elasticity experiments. 90 volunteers were selected and randomly grouped into a A, B, C, D, E, f, g, h, i, blank, 9 groups of 10, each tested on emulsions with phytochemicals a, b, d, e, f, g and h, respectively. No cosmetic or topical medicine can be used 2-3 days before the tested part. Prior to the experiment, volunteers were required to clean the face.

In the experiment, each group of volunteers is smeared with the corresponding sample for 2 times in the morning and evening, and each time is smeared with 1.0mg/cm respectively ² The amount of the composition was uniformly applied, and after 0 week (i.e., before application) and after 1 week, 2 weeks and 3 weeks of continuous use, the application site of the subject was washed at the same time every week to conduct the skin moisture content test, the wrinkle alleviation test and the skin elasticity test, respectively. Degree of wrinkle alleviation experiments, the total amount of reduced depth of wrinkles (mm) was measured by measuring the skin around the eyes and the average of the total amount of reduced depth of wrinkles was determined for the group of volunteers.

Skin elasticity test, which uses a skin elasticity tester Revisclometer RV600 to measure the part to be measured; the better the skin elasticity is indicated by the ratio of the elastic parameter, i.e., the skin elasticity value, to the maximum stretch amount at negative pressure, and the closer the ratio is to 1. The skin measurements were taken from 5 different parts of the face, 5 times each for the same test site, and the average of the skin elasticity parameters of the group of volunteers was determined.

	First week of	Second week	Third week	Fourth periphery
					a	31％	34％	36％	36％
b	29％	31％	33％	34％
					C	34％	33％	33％	31％
d	35％	36％	38％	38％
					e	31％	32％	32％	32％
f	30％	31％	31％	32％
					g	30％	31％	31％	31％
h	32％	31％	33％	34％
					Blank group
	0％	0％	0％	0％

In conclusion, the plant composition provided by the invention has good anti-aging and free radical removing capabilities, and can be used as a cosmetic additive to be added into cosmetics.

Cases of adding a vegetable composition to a facial cleanser

/>

Case of adding a phytocomposition to a face cream

Case of adding a phytocomposition to an essence

It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A plant composition with anti-aging effect, characterized in that: comprises the following components in percentage by weight: 1-20% of snow lotus herb extract, 1-20% of grape seed extract, 1-20% of evening primrose extract, 1-20% of chamomile extract, 40-60% of polyalcohol and the balance of water.

2. A plant composition with anti-aging effect according to claim 1, characterized in that: comprises the following components in percentage by weight: 1-20% of snow lotus herb extract, 1-10% of grape seed extract, 1-5% of evening primrose extract, 1-5% of chamomile extract, 50-60% of polyalcohol and the balance of water.

3. A plant composition with anti-aging effect according to claim 1, characterized in that: the polyalcohol is one or more of butanediol, propylene glycol and pentanediol.

4. A plant composition with anti-aging effect according to claim 1, characterized in that: the preparation process of the composition comprises the following steps: mixing 1-20 parts of herba Saussureae Involueratae extract, 1-20 parts of grape seed extract, 1-20 parts of evening primrose extract and 1-20 parts of flos Matricariae Chamomillae extract, adding 40-60 parts of polyalcohol, and balancing water to obtain composition with antiaging effect;

mixing 1-20 parts of herba Saussureae Involueratae extract, 1-10 parts of grape seed extract, 1-5 parts of evening primrose extract and 1-5 parts of flos Matricariae Chamomillae extract, adding 50-60 parts of polyalcohol, and balancing water to obtain the composition with antiaging effect.

5. A plant composition with anti-aging effect according to claim 1, characterized in that: the herba Saussureae Involueratae extract has flavonoids as main effective components, and purity of 1-10%.

6. A plant composition with anti-aging effect according to claim 1, characterized in that: the main functional component of the grape seed extract is anthocyanin opc, and the purity ratio is 95-99%.

7. A plant composition with anti-aging effect according to claim 1, characterized in that: the main effective component of the evening primrose extract is linoleic acid, and the purity ratio is 1-17%.

8. A plant composition with anti-aging effect according to claim 1, characterized in that: the main effective component of the chamomile extract is alpha-bisabolol with the purity ratio of 1-10%.

9. A plant composition with anti-aging effect according to claim 1, characterized in that: the composition with the anti-aging function is used as an anti-aging component to be added into cosmetics, wherein the addition amount of the composition with the anti-aging function accounts for 1% -20% of the quality of the cosmetics.

10. A plant composition with anti-aging effect according to claim 9, characterized in that: the cosmetic is in the form of solution, gel, emulsion or cream.