KR100829722B1 - Cosmetic Composition for Protecting Skin Aging Comprising the Extract of Root from Rhododendron mucronulatum as Active Ingredient - Google Patents

Abstract

The invention Rhododendron Mucronulatum ) relates to a cosmetic composition for preventing skin aging and a cosmetic composition for alleviating skin inflammation comprising a root extract as an active ingredient. The cosmetic composition of the present invention has an excellent anti-oxidant effect and wrinkle improvement effect, and has an excellent anti-inflammatory effect and does not cause skin irritation, thereby showing an excellent effect on preventing skin aging.

Rhododendron, aging, anti-inflammatory, cosmetics

Description

Cosmetic composition for preventing skin aging including rhododendron root extract as an active ingredient {Cosmetic Composition for Protecting Skin Aging Comprising the Extract of Root from Rhododendron mucronulatum as Active Ingredient}

The present invention relates to a cosmetic composition for preventing skin aging.

Oxygen, along with water, is an indispensable material for our living, but once the oxygen enters our bodies, it causes oxygen to oxidize blood vessel cells, which is very active by many causes.

Today, about 90% of the causes of the disease are identified by this free radical. The human body is composed of about 60 trillion cells, and the cell membrane is formed of the cortex so that free radicals are easy to connect. When oxidation occurs, unsaturated fatty acids turn into peroxide. This lipid peroxide damages genes DNA, RNA, proteins, cell membranes, and cellular structures, which can lead to cancer and other adult diseases, and ultimately to aging. The substance that removes or neutralizes free radicals and prevents the cells from oxidizing is called an antioxidant.

In general, when peroxidation occurs due to the free radicals of lipids, which are components of skin cells, the structure of the cell membrane is altered, resulting in cell permeability, fluidity, inactivation of membrane enzymes and transport proteins, cleavage of protein chains, DNA and RNA damage, etc. It is known that skin cells age. For this reason, efforts to remove free radicals have continued, and as a result, many sulfates have been developed.

The substances known to have antioxidant activity so far include ascorbic acid, beta-carotene, dibutylhydroxytoluene (BHT), DL-alpha-tocopherol, and the like. . However, since these substances are used as synthetic materials, they cause problems of skin safety when used for long-term use or in large amounts, or are limited in their use because of problems in stability when contained in cosmetic formulations. . Many researchers have been trying to solve these problems.

Inflammation of the skin is caused by misused drugs or ultraviolet rays from the sun. It is known that inflammation is caused by the signaling system of the immune response system. In addition, ingredients used in cosmetics may cause an allergic reaction or skin skin irritation in some cases.

Cosmetics are defined as a slight effect of applying to the skin for the protection, beautification and cleansing of the skin. Among the ingredients used in these cosmetics, preservatives, surfactants, pigments, UV absorbers and other ingredients are rather It can cause skin irritation by irritating skin cells or causing allergic reactions.

This stimulus leads consumers to disbelief in cosmetics and have a sense of rejection. Therefore, cosmetics researchers are conducting a lot of research to eliminate such inflammation and skin irritation, and are using pure substances derived from nature.

In order to prevent skin inflammation, allantoin, bisabolol, etc. are used in cosmetics. However, allantoin has a poor solubility in water and oils, and thus is limited to use in the product. In the case of bisabolol, allantoin has excellent anti-inflammatory effect but is known to cause side effects.

Throughout this specification, numerous patent documents are referenced and their citations are indicated. The disclosures of the cited patents are incorporated herein by reference in their entirety, so that the level of the technical field to which the present invention belongs and the contents of the present invention are more clearly explained.

The present inventors have conducted a lot of research in order to invent a substance effective for skin aging and dermatitis and found that the rhododendron root extract is excellent in this effect and completed the present invention.

Therefore, it is an object of the present invention to provide a cosmetic composition for preventing skin aging comprising azalea root extract as an active ingredient.

It is also an object of the present invention to provide a cosmetic composition for skin inflammation alleviation comprising azalea root extract as an active ingredient.

Other objects and advantages of the invention will be apparent from the following examples and claims.

According to one aspect of the invention, the present invention provides a cosmetic composition for preventing skin aging comprising azalea root extract as an active ingredient.

According to another aspect of the present invention, the present invention provides a cosmetic composition for alleviating skin inflammation comprising azalea root extract as an active ingredient.

The present inventors prepared extracts by various extraction methods using a plurality of natural products as a raw material, and the result of performing the task of selecting a substance excellent in antioxidant effect and skin inflammation relieving effect ( Rhododendron mucronulatum ) root extract was found to be the most suitable for the purposes of the present invention described above.

The cosmetic composition of the present invention includes azalea root extract as an active ingredient.

Rhododendron flowers bloom before the leaves in April, one at the end of the branch, but two to five are collected. Corollas are open funnels, 4-5cm in diameter, reddish purple or light red, with hairs on the outside, split into 5 ends. There are 10 stamens, white hairs at the base of the operating table, 1 pistil and much longer than the stamens. It is also called true flower bonsai. It grows in sunny places in the mountains. Its height is 2 ~ 3m and many branches are split at the upper part of stem. The twig is light brown and has scales. Leaves are alternate, long oval-shaped or inverted lanceolate, 4-7cm long, narrow at both ends, and flat. The leaf surface has some scale pieces, the back side has dense scale pieces, hairless, and petioles are 6-10mm long. In oriental medicine, flowers are used as a medicine called Yeongsanhong (迎 山 紅), which is effective for headaches caused by seawater, bronchitis and cold, and has a diuretic effect. It is distributed in Korea, Japan, China, Mongolia, etc. White azaleas for white flowers albiflorum ), hairy twigs and leaves with hairy rhododendrons (var. ciliatum ), commonly grown on the seashore and in high mountains. Among the hairy rhododendron blooming with white flowers that azaleas huinteol (for. Alba), and can sometimes see near the coast. A round or broad oval shaped leaf is called azalea (var. Latifolium ). Among the ones growing near the beach, the leaves are glossy and the mantis-like projections on both sides are called Rhododendron ( var . Maritimum ) and the fruit is thinner and longer. taquetii ). It is short in length , has small flowers, and has five stamens. It is called R. saisiuense and grows near the summit of Halla Mountain.

To date, rhododendron roots have been used in folk asthma and bronchitis. In addition, patents related to arthritis treatments are disclosed in Korean Patent No. 2003-31272. However, it is not disclosed whether azalea roots are anti-oxidant, anti-aging, or anti-inflammatory.

Cosmetic composition comprising the azalea root of the present invention exhibits an excellent anti-oxidant effect to improve the skin wrinkles and exhibits excellent skin aging prevention effect, and is effective in improving the skin inflammation caused by external substances, such as preventing skin aging Effective for alleviating skin inflammation

Azalea root extract, which is an active ingredient of the cosmetic composition of the present invention, may be prepared according to a conventional method known in the art, that is, using a conventional solvent, under the conditions of conventional temperature and pressure.

Azalea root extract, which is an active ingredient of the composition of the present invention, is prepared using a solvent selected from the group consisting of water, anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms, acetone, ethyl acetate, butyl acetate and 1,3-butylene glycol. It is preferred to be extracted, more preferably alcohol, even more preferably ethanol. The ethanol is preferably 70% ethanol. A suitable amount of the extraction solvent is 1-15 times the dry weight of azalea roots, more preferably 5-12 times, most preferably 12 times.

Rhododendron root extract of the present invention is prepared by a process comprising the following steps:

(a) adding to the dried rhododendron root a solvent selected from the group consisting of 1-10 times water, 1-4 anhydrous or hydrous lower alcohols, acetone, ethyl acetate, butyl acetate and 1,3-butylene glycol step;

(b) extracting the solvent-added rhododendron root of step (a) at 4-40 ° C. for 1-15 days;

(c) filtering the extract of step (b) followed by aging for 7-10 days at 3-5 ° C., followed by filtration; And

(d) drying the filtrate of step (c) with a rotary evaporator.

In this case, when 1,3-butylene glycol is used as the extraction solvent, it is difficult to dry using a rotary depressurization evaporator, and thus, after performing the extraction step (b), the drying loss is adjusted to 1% (w / v).

According to a specific embodiment of the present invention, the above-described extraction process is carried out as follows: First, the raw rhododendron root is washed, dried and powdered, and then 70% ethanol is used at a volume ratio of 12 times the dry weight of the rhododendron root. After the extraction for 4 days at 4-40 ℃ and left for 5 days at 3-5 ℃ aging and filtered. Subsequently, the filtrate was dried on a rotary decompression evaporator at 65 ° C. to prepare an azalea root extract.

On the other hand, the rhododendron root extract of the present invention includes not only the extract by the above-described extraction method, but also an extract that has undergone a conventional purification process. Obtained by various additional purification methods, such as, for example, separation using an ultrafiltration membrane having a constant molecular weight cut-off value, separation by various chromatography (manufactured for separation according to size, charge, hydrophobicity or affinity). The fraction is also construed to be included in the extract of Baekchulchae of the present invention.

Azalea root extract of the present invention can be prepared in a powder state by an additional process such as distillation under reduced pressure and freeze drying or spray drying.

According to a preferred embodiment of the present invention, the content of rhododendron root extract is 0.001-30.0% by weight, preferably 0.01-15.0% by weight, most preferably 0.1-5.0% by weight, based on the total weight of the cosmetic composition. When the content of the Rhododendron root extract is less than 0.001% by weight, there is a problem in showing an antioxidant effect and an anti-inflammatory effect, and when it exceeds 30.0% by weight, synergistic effects are not expected, and there is a problem in the stability of the formulation of the composition and skin irritation. There is a risk of causing.

In addition, the cosmetic composition of the present invention contains ingredients commonly used in cosmetic compositions, in addition to the azalea root extract as an active ingredient, such as conventional auxiliaries such as antioxidants, stabilizers, solubilizers, vitamins, pigments and flavorings, and Carrier.

The cosmetic composition of the present invention may be prepared in any formulation commonly prepared in the art, for example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, surfactant-containing cleansing , Oils, powder foundations, emulsion foundations, wax foundations and sprays, and the like, but are not limited thereto. More specifically, it may be prepared in the form of a flexible lotion, astringent lotion, nutrition lotion, nutrition cream, massage cream, essence, eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray or powder.

When the formulation of the cosmetic composition of the present invention is a paste, cream or gel, the carrier component is animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide. This can be used.

When the formulation of the cosmetic composition of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as the carrier component, and in particular, in the case of a spray, additionally chlorofluorohydro Propellant such as carbon, propane / butane or dimethyl ether.

When the formulation of the cosmetic composition of the present invention is a solution or emulsion, a solvent, solubilizing agent or emulsifying agent is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene. Fatty acid esters of glycol, 1,3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan.

When the formulation of the cosmetic composition of the present invention is a suspension, a liquid diluent such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester as carrier components , Microcrystalline cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

When the formulation of the cosmetic composition of the present invention is a surfactant-containing cleansing agent, the carrier component is an aliphatic alcohol sulfate, an aliphatic alcohol ether sulfate, a sulfosuccinic acid monoester, an isethionate, an imidazolinium derivative, a methyltaurate, or a sarcosinate. Fatty acid amide ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters, and the like.

Rhododendron root extract of the present invention shows an excellent antioxidant effect (see Experimental Example 1). In addition, the cosmetic composition prepared by containing the rhododendron root extract having this effect as an active ingredient is excellent in inhibiting inflammation when applied directly to the skin (Reference: Experimental Example 2), excellent skin wrinkle improvement effect (Reference: Experimental Example 3 ), Does not cause skin irritation (see Experimental Example 4).

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention in more detail, and the scope of the present invention is not limited by these examples in accordance with the gist of the present invention to those skilled in the art. Will be self-evident.

Example  1: Preparation of Rhododendron Root Extract

After washing with purified water and crushing 100 g of dried Rhododendron roots, it was put in 1.2 L of water, extracted for 5 days at 4-40 ° C., filtered with 300 mesh filter cloth, left to mature at low temperature 3-5 ° C. for 5 days, and then filtered. Filtered. The filtrate was dried at 65 ° C. on a rotary immersion evaporator to obtain an azalea root extract with a dry weight of 12.83 g.

Example  2-19: Preparation of Rhododendron Root Extract

The rhododendron root extract of Example 2-19 was obtained by extracting in the same manner as in Example 1 except for using the extraction solvent of Table 1 below.

extract Extraction solvent Dry weight of the final extract (unit: g) Example 2 10% ethanol 12.8 Example 3 20% ethanol 13.9 Example 4 30% ethanol 13.2 Example 5 40% ethanol 14.3 Example 6 50% ethanol 15.1 Example 7 60% ethanol 15.3 Example 8 70% ethanol 14.2 Example 9 80% ethanol 13.3 Example 10 90% ethanol 125 Example 11 100% ethanol 13.4 Example 12 Methanol 13.3 Example 13 n-propanol 11.5 Example 14 Isopropanol 10.6 Example 15 2-butanol 4.2 Example 16 Acetone 3.5 Example 17 chloroform 2.5 Example 18 Ethyl acetate 3.3 Example 19 Butyl acetate 2.6

Example  20: Supercritical  Preparation of Rhododendron Root Extract Using Fluid Extraction Method

Rhododendron roots were washed with purified water, dried and crushed, and then 100 grams of sample was placed in a supercritical fluid extractor (Jasco, Japan) and purified using a liquid chromatography pump (Supercritical fluid chromatograph, Jasco, Japan). Extracts up to 40 minutes every 4 minutes using carbon dioxide and a cosolvent (a mixture of alcoholic alcohol, polar solvent and squalene, a non-polar solvent, in 1: 1) at a temperature of 80 ° C and a pressure of 300 atm. Rhododendron root extract was prepared in a 10 ml glass test tube.

Experimental Example  1: Antioxidant Effect of Azalea Root Extract

Experimental Example  1-1: TBA  Antioxidant experiment

To investigate the antioxidant effect of Rhododendron root extract, TBA was performed. Fenton's reagent (2% SDS, 0.79 mM Potassium chloride, 0.25 mM Trizma base (pH 7.4), 1 μ M FeCl2, 0.025 mM H2O2) 4.8 mL, linoleic acid (Linoleic acid) 100 ㎕ And 100 μl of the sample (Examples 1-20, 1%) were mixed, light was blocked, and the reaction was performed at 55 ° C. for 16 hours , followed by addition of 100 μl of 4% BHT. 2 ml of the reaction solution, 1 ml of trichloroacetic acid, and 2 ml of 0.75% TBA were mixed, and the mixture was immersed in a water bath for 10 minutes, and then cooled after blocking light. 500 µl of the reaction solution, 100 µl of acetic acid and 200 µl of chloroform were mixed and centrifuged at 12,000 rpm for 10 minutes. 200 μl of the supernatant centrifuged was measured and absorbed at 530 nm three times, averaged, and then substituted into the following equation (2) to calculate the inhibition rate of oxidation (antioxidant effect). The results are shown in Table 2.

% Inhibition of oxidation = (control absorbance-example absorbance) / (control absorbance) × 100

sample Absorbance Oxidation inhibition rate (%) Control 1.302 - Example 1 0.542 58.37 Example 2 0.443 65.98 Example 3 0.422 67.59 Example 4 0.375 71.20 Example 5 0.310 76.19 Example 6 0.221 83.03 Example 7 0.113 91.32 Example 8 0.103 92.09 Example 9 0.334 74.35 Example 10 0.237 81.79 Example 11 0.335 74.27 Example 12 0.256 80.34 Example 13 0.445 65.82 Example 14 0.533 59.06 Example 15 0.258 80.18 Example 16 0.456 64.98 Example 17 0.587 54.92 Example 18 0.442 66.05 Example 19 0.456 64.98 Example 20 0.778 40.25

Experimental Example  1-2: DPPH  Antioxidant experiment

DPPH antioxidant experiment was conducted to investigate the antioxidant effect of Rhododendron root extract. A DPPH (1,1-diphenyl-2-picrylhydrazyl radical) solution (60M) was prepared. Then the concentration of rhododendron root extract (Examples 1-20) was adjusted to 1% and the DPPH solution was mixed in a 1: 1 ratio and then vortexed. After reacting at room temperature for 30 minutes, absorbance was measured at 520 nm to obtain free radical scavenging activity (SC) according to the following formula (2). Controls were measured using ethanol instead of samples.

% Free radical scavenging activity = (control absorbance-example absorbance) / (control absorbance) x 100

sample Free radical scavenging activity (%) Control - Example 1 52.33 Example 2 55.77 Example 3 87.98 Example 4 81.23 Example 5 78.21 Example 6 84.33 Example 7 89.33 Example 8 87.29 Example 9 79.45 Example 10 83.55 Example 11 84.33 Example 12 75.11 Example 13 76.77 Example 14 62.55 Example 15 77.33 Example 16 56.77 Example 17 50.55 Example 18 63.44 Example 19 61.23 Example 20 23.57

As can be seen from the antioxidant effect measurement results of Table 2 and Table 3, it can be seen that the rhododendron root extract exhibits an excellent antioxidant inhibition rate and free radical scavenging activity.

Production Example : Contains rhododendron root extract Cosmetic  Produce

A flexible cosmetic composition containing 1.0% by weight of the rhododendron root extract of Example 8 was prepared in the composition shown in Table 4, which is referred to as Formulation Example 1, and a flexible cosmetic composition containing no azalea root extract was prepared as Comparative Formulation Example 1. It was.

ingredient Formulation Example 1 Content (% by weight) Comparative Example 1 Content (% by weight) Rhododendron Root Extract (Example 8) 1.0 - glycerin 5.1 5.1 Propylene glycol 4.2 4.2 Tocopheryl Acetate 3.0 3.0 Liquid paraffin 4.6 4.6 Triethanolamine 1.0 1.0 Squalane 3.1 3.1 Macadamia Nut Oil 2.5 2.5 Polysorbate 60 1.6 1.6 Sorbitan sesquirrolate 1.6 1.6 Propylparaben 0.6 0.6 Carboxyl Vinyl Polymer 1.5 1.5 incense a very small amount a very small amount antiseptic a very small amount a very small amount Purified water Remaining amount Remaining amount system 100 100

Experimental Example 2 : anti-inflammatory effect of the cosmetic composition containing azalea root extract (ear edema experiment)

The anti-inflammatory effect was measured using a cosmetic composition containing the rhododendron root extract prepared in Preparation Example.

Fourteen healthy rats were divided into three groups per sample, and two rats were tested (prescription examples 1-1, 1-2, 1-3, comparative prescription examples 1-1, 1-2, 1-3). First, both ears of rats were wiped well with alcohol (ethanol), and 4 μl of each sample was applied. After 1 hour, 20 μl of acetone was applied to the left ear, and arachidonic acid, an inflammation-positive control agent, was applied to the right ear. After 1 hour again, the thickness of both ears was repeatedly measured using a micrometer to obtain an average value, and the anti-inflammatory effect was calculated according to Equation 3 below.

The results are shown in Table 5.

Anti-inflammatory effect (%) = (A-B) / B × 100

A = thickness difference from control, B = bulge thickness in control

product Swelling Anti-inflammatory effect Increased thickness Difference from control Control (purified water) 2.83 - - Prescription Example 1-1 2.43 0.40 14.1% Average 11.87% Prescription Example 1-2 2.51 0.32 11.3% Prescription Example 1-3 2.54 0.29 10.2% Prescription Example 2-1 2.80 0.03 1.1% 2.73% average Prescription Example 2-2 2.74 0.09 3.2% Prescription Example 2-3 2.72 0.11 3.9%

Through the results of measuring the anti-inflammatory effect of Table 5, the cosmetic composition of Formulation Example 1 containing the azalea root extract of the present invention, compared to the cosmetic composition of Comparative Formula 1, containing no azalea root extract, excellent anti-inflammatory It can be seen that the effect.

Experimental Example  3: containing azalea root extract Cosmetic  Wrinkle improvement effect evaluation

Wrinkle improvement effect of the cosmetic of the present invention was evaluated through a practical use test. Prepare a cream containing 1.0% by weight of the rhododendron root extract of Example 7 to the composition shown in Table 6, which is referred to as Formulation Example 2, and prepared a cream replacing the rhododendron root extract with purified water and referred to as Comparative Prescription Example 2 Wrinkle improvement effect was evaluated.

ingredient Formulation Example 2 Content (% by weight) Comparative Example 2 Content (% by weight) Rhododendron Root Extract (Example 7) 1.0 - Lipophilic monostearate 2.0 2.0 Cetearyl Alcohol 2.2 2.2 Stearic acid 1.5 1.5 Beeswax 1.0 1.0 Polysorbate 60 1.5 1.5 Sorbitan stearate 0.6 0.6 Cured Vegetable Oil 1.0 1.0 Squalane 3.0 3.0 Mineral oil 5.0 5.0 Trioctanoine 5.0 5.0 Dimethicone 1.0 1.0 Sodium magnesium silicate 0.1 0.1 glycerin 5.0 5.0 Betaine 3.0 3.0 Triethanolamine 1.0 1.0 Sodium hyaluronate 4.0 4.0 incense a very small amount a very small amount antiseptic a very small amount a very small amount Purified water Remaining amount Remaining amount system 100 100

Wrinkle improvement effect evaluation was performed as follows. Twenty 30-40 year old women were randomly divided into two groups, and the creams of Formulation Example 2 and Comparative Example 2 were washed twice every morning, and then the appropriate amount of cream was applied continuously for 2 months around the eyes. Wrinkle improvement effect of each subject was evaluated through visual observation. The experimental results are shown in Table 7 below.

Wrinkle improvement effect (visual evaluation) sample Excellent wrinkle improvement Wrinkle improvement No wrinkle improvement Effectiveness% Prescription Example 2 8 8 4 70.0 Comparative Prescription 2 One 3 16 45.0

According to the results of Table 7, the cream of the present invention containing azalea root extract (prescription example 2) showed a higher wrinkle improvement effect than the cream (comparative prescription example 2) containing no azalea root extract.

Experimental Example  4: skin irritation test

In order to examine the skin irritation of the cosmetic composition containing the rhododendron root extract of the present invention, a predetermined amount (about 0.1 g) of each sample at 5 × 20 cm in the lower arm of the arm for 30 healthy adults male and female After patching for a time, 1 hour and 24 hours after removal, the skin condition change was read visually by the following criteria, and the stimulation rate was calculated according to the following equation (4). The experimental results are shown in Table 8 below.

Criteria

-: No erythema or unusual phenomenon

+-: Slightly redder than the surroundings

+: Significantly redder than the surroundings

++: reddens and swells more heavily

Stimulus rate = {(+-) number × 1 + (+) number × 2 + (++) number × 3} / {(total) × 3} × 100

sample Judgment result Stimulation rate (%) ++ + +- - Prescription Example 2 - - One 29 1.1 Comparative Prescription 2 - - 2 28 2.2

As can be seen from the skin irritation test results of Table 8, the cosmetic composition containing the rhododendron root extract of the present invention was found to have little skin irritation.

As described in detail above, the present invention provides a cosmetic composition for preventing skin aging and a cosmetic composition for alleviating skin inflammation, comprising azalea root extract as an active ingredient. The cosmetic composition of the present invention improves skin wrinkles and prevents skin aging through an excellent antioxidant effect, and is a very safe composition in terms of skin irritation that is a problem in cosmetics through an anti-inflammatory effect.

Having described the specific part of the present invention in detail, it is apparent to those skilled in the art that the specific technology is merely a preferred embodiment, and the scope of the present invention is not limited thereto. Thus, the substantial scope of the present invention will be defined by the appended claims and equivalents thereof.

Claims (5)

Rhododendron mucronulatum ) Skin anti-aging cosmetic composition comprising a root extract as an active ingredient. Rhododendron mucronulatum ) cosmetic composition for skin inflammation relief comprising root extract as an active ingredient. The extract of claim 1 or 2, wherein the azalea root extract is selected from the group consisting of water, anhydrous or hydrous lower alcohol having 1-4 carbon atoms, acetone, ethyl acetate, butyl acetate and 1,3-butylene glycol. Cosmetic composition, characterized in that extracted with a solvent. The cosmetic composition according to claim 1 or 2, wherein the content of the rhododendron root extract is 0.0001-30.0 wt% based on the total weight of the cosmetic composition. 3. The cosmetic composition according to claim 1 or 2, wherein the cosmetic composition is a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation And a formulation selected from the group consisting of sprays.