KR100638053B1 - Cosmetic composition for abirritating skin containing extract of rumex crispus as active ingredient - Google Patents

Abstract

A cosmetic composition comprising an extract of Rumex crispus is provided to inhibit skin irritation caused by skin irritable materials contained in general cosmetic products and be useful for preventing or treating pathological symptom induced by the skin irritation. The cosmetic composition for alleviating skin irritation comprises 0.0001-10 wt.% of an extract of Rumex crispus as an effective ingredient, which is prepared by using a solvent selected from the group consisting of water, C1-4 alcohol, acetone, ethyl acetate, butyl acetate, and 1,3-butylene glycol. The composition further comprises at least one skin irritation inducing material selected from the group consisting of lactic acid, glycolic acid, salicylic acid, and retinoic acid.

Description

Cosmetic composition for relieving skin irritation containing active extract as an active ingredient {Cosmetic Composition for Abirritating Skin Containing Extract of Rumex crispus as Active Ingredient}

The present invention relates to a cosmetic composition for alleviating skin irritation, and more particularly, to provide a cosmetic composition for alleviating skin irritation, which contains an extract of Sorugyun as an active ingredient.

Recently, the number of consumers who feel sensitive skin is increasing. In the survey of general consumers, 30-40% of respondents said they were sensitive skin, and this rate is increasing. The increasing rate of sensitive skin is due to the increase in ultraviolet radiation due to the destruction of the ozone layer, the drying of the living space, the constitution of allergies, stress, and the increase of chemical harmful substances. On the other hand, the recent shift toward consumer-friendly and hypoallergenic consumerism has also been suggested to be a factor in improving awareness of sensitive skin. Accordingly, interest in substances that alleviate skin irritation caused by cosmetic products Is rising.

In general, various raw materials are used to make cosmetics, and typically 20 to 50 kinds of raw materials are used. These ingredients have been proved to be safe through skin irritation tests, but when applied to the product can cause irritation, itching and allergies to the skin. However, these stimulus reactions do not happen to everyone, and may only happen to certain people.

Skin irritation that may occur with the use of cosmetics includes irritation such as itching, stinging and burning, and erythema and edema. Contact dermatitis includes irritant contact dermatitis, allergic contact dermatitis, sensory irritation, and phototoxic dermatitis, but it is difficult to clearly distinguish them, and most of them are mixed with each other.

Above all, in order for skin irritation to occur, first, skin penetration by cosmetics must occur, and they interact with the epidermis or dermis cells to activate the immune system and cause irritation. In order to alleviate such skin irritation, various methods, such as a method of removing skin irritation-inducing substances, have been mobilized, but functional cosmetics have recently been increasing.

Therefore, cosmetics manufacturers are making efforts to minimize the irritation of the cosmetic raw material by applying a commonly used irritant substance to the product. However, this study is limited because the functional material itself often acts as an irritant. Therefore, it is necessary to select a substance that can reduce side effects caused by cosmetics and alleviate skin irritation while maintaining the effects of the functional raw materials.

The present inventors have diligently tried to solve the above-described needs of the art, and as a result, it was confirmed that the extract of Soru-Jiung has an excellent effect of alleviating cellular stimulation and suppressing inflammation from the irritant, and when used in cosmetics, the effect of alleviating skin irritation It was confirmed that the excellent to complete the present invention.

Accordingly, it is an object of the present invention to provide a cosmetic composition for skin irritation relief comprising the extract of Soru-Jin as an active ingredient.

Other objects and advantages of the present invention will become apparent from the following detailed description and claims.

According to an aspect of the present invention, the present invention provides a cosmetic composition for alleviating skin irritation containing Rumex crispus extract as an active ingredient.

The inventors of the present invention have prepared extracts using a large number of natural products as a raw material, and as a result of performing the work of selecting substances excellent in stimulating cell stimulation and inhibiting inflammation from stimulants, the extracts of Soru-Jiung are most suitable for the purpose of the present invention described above. I found that it was a match.

Rumex crispus is called perennial herb, canopy, or muzzle, and is a perennial herb that grows dry in midsummer and grows again when cool. Young leaves are eaten as herbs and are effective for ringworm, athlete's foot and eczema. Since ancient times, it has been used for skin diseases such as amelioration, scabies and skin cancer, and it has been used for cystitis and colitis. In the fall, the roots were dug up and rolled up and dried in the sun called Yangje-geun, which was substituted for the Chinese medicine called rhubarb.

Soru-Ji extract, an active ingredient of the cosmetic composition of the present invention, has an anti-inflammatory and anti-inflammatory effect from a novel stimulating source.

In the present invention, the extract is derived from various organs or parts (eg, leaves, flowers, roots, stems, branches, shells, fruits, etc.) of the sarcasm, preferably all organs of the sarcasm. Means an extract obtained from the whole of the grass.

The extracts of the present invention can be prepared according to conventional methods known in the art, i.e., under conventional conditions of temperature and pressure, using conventional solvents.

Soruja extract, which is an active ingredient of the composition of the present invention, is prepared using a solvent selected from the group consisting of water, anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms, acetone, ethyl acetate, butyl acetate, and 1,3-butylene glycol. Preference is given to extracting, more preferably ethyl alcohol, even more preferably 50-90% ethyl alcohol, most preferably 70% ethyl alcohol. A suitable amount of the extraction solvent is 1-10 times the dry weight of the boric acid, more preferably 1-5 times.

An extract of the present invention is prepared by a process comprising the following steps: (a) 1 to 5 times water, 1-4 anhydrous or hydrous lower alcohols, acetone, ethyl acetate, butyl acetate And adding a solvent selected from the group consisting of 1,3-butylene glycol; (b) filtering the solvent added boricum of step (a) and concentrating at 40-100 ° C .; And (c) filtering and drying the components concentrated in step (b) to dissolve in 1,3-butylene glycol.

According to one specific embodiment of the present invention, the above-described extraction process is carried out as follows: first, the raw sorbet is washed, dried and broken into small pieces, and then 70% ethyl alcohol is dried at 5% of dry weight. Precipitate for 5 days by addition in fold volume ratio. The sorbus extract is then prepared by filtration at 300 mesh and then concentrating at 80 ° C. using a vacuum decompression concentrator to obtain sorbus extract powder and then dissolving it in 1,3-butylene glycol for application to the product.

On the other hand, the rubbing extract of the present invention includes not only the extract by the above-described extraction method, but also the extract that has undergone a conventional purification process. Obtained by various additional purification methods, such as, for example, separation using ultrafiltration membranes having a constant molecular weight cut-off value, separation by various chromatography (manufactured for separation according to size, charge, hydrophobicity or affinity). Fractions are also construed as being included in the extract of the present invention.

Soruja extract of the present invention may be prepared in a powder state by an additional process such as vacuum distillation and freeze drying or spray drying.

According to a preferred embodiment of the present invention, the content of Soru-Ji extract is 0.0001-10.0% by weight relative to the total weight of the skin composition for alleviating the skin irritation of the present invention. When the content of the extract is less than 0.0001%, the effect is less likely to appear, and when more than 10% is more likely to cause irritation on the skin, it may also have a significant effect on the stabilization of the formulation. More preferably, the content of the sorujeuk extract contained in the cosmetic composition for alleviating the skin irritation of the present invention is 0.5-5%, most preferably 1.0-3.0%.

The cosmetic composition of the present invention may be prepared as a composition comprising the extract of Soru-Jin as an active ingredient, and may be applied before or after applying the cosmetic composition having high skin irritation to the skin. In addition, the extract may be applied to the skin by additionally added to the cosmetic composition having a large skin irritation.

The cosmetic composition with high skin irritation is selected from the group consisting of lactic acid, glycolic acid, salicylic acid and retinoic acid, preferably lactic acid. Therefore, according to another aspect of the present invention, the present invention provides a cosmetic composition further comprising lactic acid, a skin stimulant, together with the extract of Soru-Jung as a skin stimulant.

The ingredients included in the cosmetic composition of the present invention include ingredients commonly used in the composition in addition to the extracts as the active ingredient, and include, for example, conventional auxiliaries such as antioxidants, stabilizers, solubilizers, vitamins, pigments and flavorings, And carriers.

The compositions of the present invention may be prepared in any formulation conventionally prepared in the art, for example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, surfactant-containing cleansing, It may be formulated as an oil, powder foundation, emulsion foundation, wax foundation, spray, and the like, but is not limited thereto. More specifically, when the composition of the present invention is used as a cosmetic composition, it is prepared in the form of a flexible lotion, nutrition lotion, nutrition cream, massage cream, essence, eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray or powder Can be.

When the formulation of the present invention is a paste, cream or gel, animal oils, vegetable oils, waxes, paraffins, starches, trachants, cellulose derivatives, polyethylene glycols, silicones, bentonites, silicas, talc or zinc oxide may be used as carrier components. Can be.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used, in particular in the case of a spray, additionally chlorofluorohydrocarbon, propane Propellant such as butane or dimethyl ether.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizing agent or emulsifying agent is used as the carrier component, such as water, ethyl alcohol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, Fatty acid esters of 1,3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan.

When the formulation of the present invention is a suspension, water, diluents such as water, ethyl alcohol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Crystalline cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

When the formulation of the present invention is a surfactant-containing cleansing, the carrier component is aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide. Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters and the like can be used.

The cosmetic composition containing the extract of Soru-Jin of the present invention does not cause skin irritation by itself, greatly reduces skin irritation caused by cosmetic raw materials, especially lactic acid, and suppresses inflammation developed by skin irritation, thereby developing by skin irritation. It has the effect of preventing and treating inflammation.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention in more detail, and it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples according to the gist of the present invention. .

Preparation Example 1 Preparation of Soru-Zip Extract

1 kg of washed, dried and finely cut Rumex crispus was precipitated in 5 L of an aqueous solution of ethyl alcohol and water at 7: 3 (v / v) for 5 days, filtered through 300 mesh, and then vacuum reduced. Concentrated at 80 ° C. using a concentrator. The soruja concentrated powder thus obtained was dissolved in 1,3-butylene glycol for easy application to the product again.

Experimental Example 1: Stimulation of Sorbus extracts against skin cell stimulation by lactic acid

In order to confirm that the extract of the present invention, Soru-Ji, has a skin irritation-releasing effect, a cell stimulation relaxation experiment was performed by lactic acid. Human skin cells, fibroblasts, were cultured in T-75 flasks containing DMEM (sigma) (Falcon, USA) until about 80% growth, and then in 96-well plates (Falcon, USA) containing DMEM. Incubate for 12 hours until 1 × 10 ⁵ cells / well. After culturing the cells, the microscope confirmed whether the cells are completely attached and well formed, and experimented as follows using 0.2% lactic acid as a skin cell stimulator. Normal skin cells generally die at the concentration of lactic acid. 200 μl of DMEM containing 0.2% lactic acid was added to each 96 wells of the plate on which the fibroblasts were cultured, and then 50, 100, 200, 500 and 1,000 μg / ml of the extracts prepared in Preparation Example 1, respectively. Added. As a control group, neither lactic acid nor sorbus extract was added, and in the comparative group, only lactic acid and only sorbus extract were added separately.

After 12 h of addition of the test substance, 10 μg of MTT ([3- (4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazolium bromide) reagent was added to each well to compare the viability of the cells. After the addition, and left for 4 hours, the absorbance of each well was measured using an ELISA reader (Molecular Dervices), and cell viability was measured by the following equation, and the results are shown in Table 1 below.

Cell viability (%) = [(control absorbance-test substance absorbance) / control absorbance] x 100

Cell survival rate (%) Concentration of extract (µg / ml) Cell survival rate (%) Sorousum Extract Soruch Extract + Lactic Acid Lactic acid 50 99.1 32.8 0 100 98.7 48.7 0 200 98.0 58.4 0 500 97.5 77.2 0 1000 96.4 90.4 0

As shown in Table 1, the extract of Soru-Ji had almost no cell stimulation and did not affect cell survival. In addition, the cell death by lactic acid increased the survival rate of the cells as the treatment concentration of the extract was increased. Therefore, it can be seen that the extract of Soru-Jin has an effect of inhibiting skin cell death by alleviating skin cell stimulation caused by lactic acid.

Experimental Example 2: Evaluation using anti-inflammatory effect evaluation method-methyl nicotinate

Twenty subjects with healthy skin were selected to determine the location for the experiment on the upper arm, and the skin color was measured using a chromameter (Minolta CR 300, Minolta) for each location. Skin color was evaluated by the a * value which shows the redness of skin among L *, a *, and b * values which show skin color. To the cream having the composition of Formulation Example 4, the cream prepared so as to contain the extracts prepared in Preparation Example 1 in concentrations of 0.1, 0.2, 0.5, and 1% was applied to the skin upper arm six times at 1 hour intervals. Finally, after 1 hour after the product was applied, the applied sample was wiped clean with lukewarm water and dried. After 30 minutes of drying, 0.04% methyl nicotinate (Aldrich Chemical Company), an inflammation-inducing agent, was soaked with 80 μg of paper disc and placed on the upper arm for 1 minute and 30 seconds. After 1 minute and 30 seconds, the paper disc was removed and the remaining methyl nicotinate was wiped clean with running water. When inflammation is induced after 20-30 minutes, erythema develops. The a * value of the erythema was measured using a chromameter (Minolta CR 300, Minolta). Substituting the measured a * value into the following equation calculates the inhibitory effect of the inflammation, and the results are shown in Table 2. The experimental group that was not coated with the cream containing the extract was used as a control. Inflammatory inhibitory effect of the control group was set to 0%, and the inflammatory inhibitory effect of the extract of the present invention was compared.

Inflammatory inhibitory effect = [(control a * value-test substance a * value) / control a * value] × 100

Concentration of Sorujax Extract in Cream Formulation (%) Inflammatory inhibitory effect (%) 0.1 27 0.2 33 0.5 48 One 57

As shown in Table 2, the cream containing the extract of Soru-Jin increased the inhibitory effect on inflammation that may be developed by skin irritation in a concentration-dependent manner of the extract. Therefore, it can be seen that the cosmetic composition comprising the extract of the rubbing extract of the present invention has an anti-inflammatory effect.

Experimental Example 3: Skin irritation relaxing effect of Soru-Ji extract I- Human skin patch test

When the extract of the present invention was directly applied to the human skin, human skin patch test was carried out to check whether it has a skin irritation-releasing effect. The subjects of this study were 15 subjects who had no history of hypersensitivity to skin irritation and have no skin disease or skin allergy. The age distribution of the subjects was 25-34 years old and the mean age was 29 years old. To the test material of Example 1, Comparative Example 1 and Comparative Example 2 was prepared in the composition of Table 3.

Furtherance Content (% by weight) Example 1 Comparative Example 1 Comparative Example 2 A Sorousum Extract 0.1 - - Lactic acid 5.0 5.0 - Wagrinol 4.0 4.0 4.0 Liquid paraffin 3.0 3.0 3.0 B Arlacel 165 1.0 1.0 1.0 Emulsion 1618 3.0 3.0 3.0 Sepigel 305 0.8 0.8 0.8 Na-lactate (60%) 2.0 2.0 2.0 Distilled water Remaining amount Remaining amount Remaining amount Sum 100 100 100

The test site was first wiped off with 70% ethyl alcohol and dried. 15 μg of the prepared test substance was added dropwise into a Fin chamber (Finn chamber, 100 × 10, EPITEST, Finland), and then sealed in the forearm inner part of the test subject. The patch was applied for 24 hours, the patch was removed, and the test site was marked with a marker pen. After patching, the extent of stimulation after 24 hours and 48 hours, respectively, was examined by using a magnifying glass (8MC-150, DAZOR, United States of America) for erythema and edema.

Skin response was determined according to the rules of the International Contact Dermatitis Research Group (ICDRG) (Table 4), the average skin reactivity was calculated by the following equation 3 and the results are shown in Table 5.

Evaluation criteria and score of skin reaction score Evaluation standard 0 No response 0.5 Faint or light erythema One Boundary but weak erythema, edema and papules 2 Pronounced erythema, papules and vesicles 3 Severe erythema and alveolar, scleroderma

Mean skin responsiveness (mean score) = {(score × number of respondents) / (maximum score × total number of subjects)} × 100

Skin irritation degree Example 1 Comparative Example 1 Comparative Example 2 Average skin reactivity (n = 15) 1.94 3.06 0.83 Judgment Light stimulation Heavy stimulation Unstimulated

Through Table 5, it was confirmed through the patch test that the cosmetic composition of the present invention comprising the extract of Soru-Ju significantly reduces skin irritation caused by lactic acid acting as a stimulating agent in cosmetics.

Experimental Example 4: Skin irritation relaxing effect II-stinging test

The subjects were tested for 15 subjects. The age distribution was 25-33 years old and the mean age was 30 years old. Sweating for 15 minutes using a steam generator, then a sufficient amount of Sample Example 1 and Comparative Example 1 (compositions in Table 3) are applied to the hands and centered around the nose and cheeks on the left and right sides, respectively. Rubbed strongly. Sting grade is classified into Intensive stinging, which occurs within 30 seconds according to the time of stimulus response after sample application, Mild stinging for 2.5 minutes, Moderate stinging for 5 minutes, and Delayed stinging for 8 minutes. After the evaluation, the results are shown in Table 6.

Skin irritation degree Example 1 Comparative Example 1 Response score 44 70 % Reaction (n = 15) 1.39 2.22 Judgment Unstimulated Light stimulation

As can be seen from the test results of Table 6, it can be seen that the test substance containing Soru-Ji extract greatly reduces skin irritation caused by lactic acid acting as a stimulating agent in cosmetics.

Experimental Example 5 Usability Evaluation

Thirty female subjects in their twenties and thirties were evaluated for the usability of the cosmetic composition of the present invention comprising the extract. A cream having the composition of Formulation Example 4, containing 3.0% of the Soruja extract prepared in Preparation Example 1, was applied to the subject for 10 days. Subsequently, lactic acid at a concentration of 2% was applied for 5 days, at which time the cream containing Soru-Jin extract was used together. Then, after one week, the presence of erythema was confirmed by the subject, and the results are shown in Table 7.

Skin reaction degree Number of subjects Cream containing extracts Cream without extract No erythema 26 16 Very slight erythema 3 9 Clear erythema One 3 Severe erythema - 2

Through the results of Table 7, it can be seen that the cosmetic composition of the present invention containing the extract of Soru-Ji significantly reduces side effects (eg, erythema) by alleviating skin irritation caused by lactic acid acting as a stimulating agent of cosmetics. .

In the following formulation example, the composition of the cosmetic composition of the present invention containing the soruja extract prepared in Preparation Example 1 will be described in detail, but the composition of the present invention is not limited only to the following examples.

Formulation Example 1: Softening Longevity

A flexible longevity containing Soru-Ji extract as shown in Table 8 below was prepared according to a conventional method.

ingredient Content (% by weight) Sorousum Extract 1.0 glycerin 6.0 1,3-butylene glycol 3.0 PEG 1500 1.0 Allantoin 0.1 DL-panthenol 0.3 EDTA-2Na 0.02 Benzophenone-9 0.04 Sodium hyaluronate 5.0 ethanol 10.0 Octicdodeceth-16 0.2 Polysorbate 20 0.2 Preservative, fragrance, coloring a very small amount Distilled water Remaining amount Sum 100

Formulation Example 2: Converging Cosmetic Water

As shown in Table 9 below, astringent cosmetic water containing the extract of Soru-Ji was prepared according to a conventional method.

ingredient Content (% by weight) Sorousum Extract 1.0 glycerin 2.0 1,3-butylene glycol 2.0 Allantoin 0.2 DL-panthenol 0.2 EDTA-2Na 0.02 Benzophenone-9 0.04 Sodium hyaluronate 3.0 ethanol 15.0 Polysorbate 20 0.3 Witch Hagel Extract 2.0 Citric acid a very small amount Preservative, fragrance, coloring a very small amount Distilled water Remaining amount Sum 100

Formulation Example 3: Nutrients

As shown in Table 10 below, the nutritious longevity containing Soru-Ji extract was prepared according to a conventional method.

ingredient Content (% by weight) Sorousum Extract 3.0 Glyceryl Stearate SE 1.5 Stearyl alcohol 1.5 lanolin 1.5 Polysorbate 1.3 Sorbitan stearate 0.5 Cured Vegetable Oil 1.0 Mineral oil 5.0 Squalane 3.0 Trioctanoine 2.0 Dimethicone 0.8 Tocopherol Acetate 0.5 Carboxyvinyl Polymer 0.12 glycerin 5.0 1,3-butylene glycol 3.0 Sodium hyaluronate 5.0 Triethanolamine 0.12 Preservative, fragrance, coloring a very small amount Distilled water Remaining amount Sum 100

Formulation Example 4: Nutrition Cream

As shown in Table 11, a nutritive cream containing Soru-Ji extract was prepared according to a conventional method.

ingredient Content (% by weight) Sorousum Extract 3.0 Lipophilic monostearate 2.0 Stearyl alcohol 2.2 Stearic acid 1.5 Beeswax 1.0 Polysorbate 60 1.5 Sorbitan stearate 0.6 Cured Vegetable Oil 1.0 Squalane 3.0 Mineral oil 5.0 Trioctanoine 5.0 Dimethicone 1.0 glycerin 5.0 Betaine 3.0 Triethanolamine 1.0 Sodium hyaluronate 4.0 Preservative, fragrance, coloring a very small amount Distilled water Remaining amount Sum 100

Formulation Example 5: Massage Cream

A massage cream containing an extract of Soru-ja extract as shown in Table 12 below was prepared according to a conventional method.

ingredient Content (% by weight) Sorousum Extract 2.0 Lipophilic Monostearic Acid Glycerin 1.5 Cetearyl Alcohol 1.5 Stearic acid 1.0 Polysorbate 60 1.5 Sorbitan stearate 0.6 Isostearyl Isosterate 5.0 Squalane 5.0 Mineral oil 35.0 Dimethicone 0.5 Hydroxyethyl cellulose 0.12 glycerin 6.0 Triethanolamine 0.7 Preservative, fragrance, coloring a very small amount Distilled water Remaining amount Sum 100

Formulation Example 6: Essence

As shown in Table 13 below, the essence containing Soru-Ji extract was prepared according to a conventional method.

ingredient Content (% by weight) Sorousum Extract 3.0 glycerin 10.0 Betaine 5.0 PEG 1500 2.0 Allantoin 0.1 DL-panthenol 0.3 EDTA-2Na 0.02 Benzophenone-9 0.04 Hydroxyethyl cellulose 0.1 Sodium hyaluronate 8.0 Carboxy Vinyl Polymer 0.2 Triethanolamine 0.18 Octyldodecanol 0.3 Octyldodeceth-16 0.4 ethanol 6.0 Preservative, fragrance, coloring a very small amount Distilled water Remaining amount Sum 100

Formulation Example 7: Pack

As shown in Table 14 below, the pack containing the extract was prepared according to a conventional method.

ingredient Content (% by weight) Sorousum Extract 3.0 Polyvinyl alcohol 15.0 Cellulose gum 0.15 glycerin 3.0 PEG 1500 2.0 Chicdestrin 0.15 DL-panthenol 0.4 Allantoin 0.1 Glycyrisin Monoammonium 0.3 Nicotinamide 0.5 ethanol 6.0 PEG 40 Cured Castor Oil 0.3 Preservative, fragrance, coloring a very small amount Distilled water Remaining amount Sum 100

As described above, the present invention provides a cosmetic composition for alleviating the skin irritation, which contains the extract of Sorugung as an active ingredient. The extract of the present invention is useful not only to suppress skin irritation caused by skin irritant raw materials contained in general cosmetics, but also to prevent or treat pathological symptoms (eg, skin inflammation) caused by skin irritation.

Having described the specific part of the present invention in detail, it is apparent to those skilled in the art that the specific technology is merely a preferred embodiment, and the scope of the present invention is not limited thereto. Thus, the substantial scope of the present invention will be defined by the appended claims and equivalents thereof.

Claims (8)

A cosmetic composition for alleviating skin irritation containing Rumex crispus extract as an active ingredient. The extract of claim 1, wherein the extract is extracted using a solvent selected from the group consisting of water, anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms, acetone, ethyl acetate, butyl acetate, and 1,3 butylene glycol. Cosmetic composition for skin irritation relief, characterized in that. The cosmetic composition for alleviating skin irritation according to claim 2, wherein the extract is extracted using ethyl alcohol as a solvent. The cosmetic composition for alleviating skin irritation according to claim 3, wherein the ethyl alcohol is 70% ethyl alcohol. The cosmetic composition for alleviating skin irritation according to claim 1, wherein the content of the extract is 0.0001-10% by weight based on the total weight of the composition. The cosmetic composition for alleviating skin irritation according to claim 1, wherein the composition further comprises a skin irritation causing substance selected from the group consisting of lactic acid, glycolic acid, salicylic acid and retinoic acid. The cosmetic composition for alleviating skin irritation according to claim 6, wherein the composition further comprises lactic acid. 8. The composition of claim 1, wherein the composition is a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation Cosmetic composition for alleviating skin irritation, characterized in that it has a formulation selected from the group consisting of wax foundation and spray.