CN116236528A - 一种护肝养肝的配方及其制备方法 - Google Patents
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Abstract
本发明公开了一种护肝养肝的配方及其制备方法，其制备原料按照重量份数计配比如下：水飞蓟7‑11份、丹参10‑15份、葛根20‑25份、决明子15‑20份、菊花10‑15份、醋五味子15‑20份、绞股蓝5‑10份。本发明护肝养肝的配方及其制备方法，主要由水飞蓟、丹参、葛根、决明子、菊花、醋五味子、绞股蓝7味中药配制而成，以水飞蓟、葛根、丹参为君药，用以粼选保肝、利胆、活血化瘀；以决明子、菊花为臣药，清沥肝胆；以五味子为佐药补肾固本；以绞股蓝为使药，补虚益气，助行诸药，达到养肝护肝的功效。
Description
技术领域
本发明涉及中药配方技术领域，特别是涉及一种护肝养肝的配方及其制备方法。
背景技术
中医认为“养肝就是养命”。养肝需要排毒、清脂、败火、益气等多个方面进行，目前现有配方和产品都只是单一方面或者少数方面有一定功效，不能达到全面护肝、养肝的作用，为此，我们提出一种护肝养肝的配方及其制备方法。
发明内容
本发明的目的在于提供一种护肝养肝的配方及其制备方法，以解决上述背景技术中提出的现有的现有配方和产品都只是单一方面或者少数方面有一定功效，不能达到全面护肝、养肝的作用的问题。
为实现以上目的，本发明通过以下技术方案予以实现：一种护肝养肝的配方及其制备方法，其制备原料按照重量份数计配比如下：水飞蓟7-11份、丹参10-15份、葛根20-25份、决明子15-20份、菊花10-15份、醋五味子15-20份、绞股蓝5-10份。
可选的，其制备原料按照重量份数计配比如下：水飞蓟9份、丹参12份、葛根24份、决明子18份、菊花12份、醋五味子18份、绞股蓝7份。
可选的，所述配方为颗粒剂、片剂或胶囊剂。
本发明的另一目的在于提供上述组合物的制备方法，其包括以下步骤：
S1、按照上述配比选取水飞蓟、丹参、葛根、决明子、菊花、醋五味子、绞股蓝洗净后备用；
S2、将步骤S1准备好的原料加水煎煮2-8次，收集提取液，每次提取完，对提取液进行过滤，得到滤液；
S3、将步骤S2获取的滤液减压浓缩成相对密度1.0-1.5的清膏，放凉冷却成浸膏；
S4、将步骤S3得到的浸膏干燥、粉碎、混合、包装制成颗粒剂或胶囊剂或片剂。
可选的，所述步骤S1中，采用的中药材烘干机，烘干温度为55℃，烘干时间30-50min。
可选的，所述步骤S2中，每次加水提取的时间为0.6～2小时。
可选的，所述步骤S4中的干燥方法为喷雾干燥法或真空干燥法。
本发明护肝养肝的配方及其制备方法具有以下优点：该配方以水飞蓟、葛根、丹参为君药，用以粼选保肝、利胆、活血化瘀；以决明子、菊花为臣药，清沥肝胆；以五味子为佐药补肾固本；以绞股蓝为使药，补虚益气，助行诸药。达到养肝护肝的功效。
具体实施方式
为了使本发明的目的、技术方案及优点更加清楚明白，以下结合实施例，对本发明进行进一步详细说明。应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。若无特别说明，本发明选用的原料和设备均为市售所得。且所有原料符合国家相关卫生标准。
本发明提供一种技术方案：一种护肝养肝的配方及其制备方法，其可以为颗粒剂、片剂或胶囊剂，其制备方法包括以下步骤：
S1、按照配比选取水飞蓟9份、丹参12份、葛根24份、决明子18份、菊花12份、醋五味子18份、绞股蓝7份洗净后备用，采用清水对中药进行清洗，清洗必要时可配合喷头清洗，洗净后采用的中药材烘干机，烘干温度为55℃，烘干时间30-50min；
S2、将步骤S1准备好的原料加水煎煮2-8次，每次加水提取的时间为0.6～2小时，收集提取液，每次提取完，对提取液进行过滤，得到滤液，过滤要确保提取液中无杂质；
S3、将步骤S2获取的滤液减压浓缩成相对密度1.0-1.5的清膏，放凉冷却成浸膏，冷却时可配合风扇吹风加快凉冷效率；
S4、将步骤S3得到的浸膏干燥、粉碎、混合、包装制成颗粒剂或胶囊剂或片剂，干燥方法为喷雾干燥法或真空干燥法，喷雾干燥法经过喷雾干燥短时间内将药液干燥成固体粉末或颗粒，可直接用于制粒、压片，或制成胶囊等，有效降低了中药的服用剂量，喷雾干燥是一种热处理加工工艺，液体物料通过送料泵泵入喷雾干燥塔中，经喷嘴雾化成小液滴，塔内的高温使液滴中水分迅速蒸发，制得干燥颗粒状的产品，物料通过雾化器的雾化作用雾化成直径细小的雾滴，增大料液的传热面积，雾化之后的细小雾滴与高温热空气直接接触过程中迅速蒸发大部分水分，从而把料液干燥成粉体或颗粒状产品的过程，在此过程中物料与环境之间发生热量和质量的交换，干燥之后的物料为粉末状物料和气体状溶剂，生产过程中一般采用旋风分离加布袋除尘器的方法加以分离；
真空干燥法是利用低温条件下水的升华性能，使物料低温脱水而达到干燥目的一种方法。先将湿物料在其冰点温度下冻结，得到稳定的固体骨架，然后在适合的真空度下进行升温，使冰直接升华为水蒸气，再利用真空系统的冷凝器将水蒸气凝结，从而获得干燥产物。
本发明提供的组合物组方中无毒性药物，且所有原料均为药食同源中药，安全性好；本发明原料中未包含贵重的中药材，种类简单，市场上量多价廉，且本发明制备方法流程简洁，制备方便，无需特种设备，节省人力物力，具有广阔的市场前景。
将经过上述制备方法制备出来的配方进行服用实施效果如下：
河南信阳的陈先生，长期肝硬化，人异常消瘦，身上伴随蜘蛛痣，持续3年时间，服用本发明制出的配方半年后，不再出现腹胀、皮肤发黄和乏力的现象，蜘蛛痣的症状消失。
河南郑州的李先生，乙肝患者，人身体消瘦，谷丙转氨酶数值异常，服用本发明制出的配方3个月后，谷丙转氨酶数值恢复正常，人精神好转。
安徽阜阳的郑女士，一年前查出肝硬化，人异常消瘦，服用本发明制出的配方3个月后，人精神好转，不再出现腹胀、皮肤发黄和乏力的现象。
结合上述实施案例可以得出该配方以水飞蓟、葛根、丹参为君药，用以粼选保肝、利胆、活血化瘀；以决明子、菊花为臣药，清沥肝胆；以五味子为佐药补肾固本；以绞股蓝为使药，补虚益气，助行诸药。达到养肝护肝的功效。
虽然本发明披露如上，但本发明并非限定于此。任何本领域技术人员，在不脱离本发明的精神和范围内，均可作各种更动与修改，因此本发明的保护范围应当以权利要求所限定的范围为准。
Claims (7)
1.一种护肝养肝的配方，其特征在于，其制备原料按照重量份数计配比如下：水飞蓟7-11份、丹参10-15份、葛根20-25份、决明子15-20份、菊花10-15份、醋五味子15-20份、绞股蓝5-10份。
2.根据权利要求1所述的一种护肝养肝的配方，其特征在于，其制备原料按照重量份数计配比如下：水飞蓟9份、丹参12份、葛根24份、决明子18份、菊花12份、醋五味子18份、绞股蓝7份。
3.根据权利要求1所述的一种护肝养肝的配方，其特征在于，所述配方为颗粒剂、片剂或胶囊剂。
4.根据权利要求1-3任一项所述的一种护肝养肝的配方的制备方法，其特征在于，包括以下步骤：
S1、按照上述配比选取水飞蓟、丹参、葛根、决明子、菊花、醋五味子、绞股蓝洗净后备用；
S2、将步骤S1准备好的原料加水煎煮2-8次，收集提取液，每次提取完，对提取液进行过滤，得到滤液；
S3、将步骤S2获取的滤液减压浓缩成相对密度1.0-1.5的清膏，放凉冷却成浸膏；
S4、将步骤S3得到的浸膏干燥、粉碎、混合、包装制成颗粒剂或胶囊剂或片剂。
5.根据权利要求4所述的一种护肝养肝的配方的其制备方法，其特征在于，所述步骤S1中，采用的中药材烘干机，烘干温度为55℃，烘干时间30-50min。
6.根据权利要求4所述的一种护肝养肝的配方及其制备方法，其特征在于，所述步骤S2中，每次加水提取的时间为0.6～2小时。
7.根据权利要求4所述的一种护肝养肝的配方及其制备方法，其特征在于，所述步骤S4中的干燥方法为喷雾干燥法或真空干燥法。
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| CN104432023A (zh) * | 2014-11-03 | 2015-03-25 | 深圳市麦金利实业有限公司 | 具有保护肝损伤的制品 |
| CN104474459A (zh) * | 2014-11-25 | 2015-04-01 | 梧州市人民医院 | 具有保肝作用的中药制剂及其制备方法 |
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| CN104432023A (zh) * | 2014-11-03 | 2015-03-25 | 深圳市麦金利实业有限公司 | 具有保护肝损伤的制品 |
| CN104474459A (zh) * | 2014-11-25 | 2015-04-01 | 梧州市人民医院 | 具有保肝作用的中药制剂及其制备方法 |
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