CN116199733A - 融合蛋白合成的方法和产品 - Google Patents

融合蛋白合成的方法和产品 Download PDF

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Publication number
CN116199733A
CN116199733A CN202211548024.1A CN202211548024A CN116199733A CN 116199733 A CN116199733 A CN 116199733A CN 202211548024 A CN202211548024 A CN 202211548024A CN 116199733 A CN116199733 A CN 116199733A
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China
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peptide linker
protein
peptide
amino acid
seq
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CN202211548024.1A
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English (en)
Chinese (zh)
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M·豪沃思
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Oxford University Innovation Ltd
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Oxford University Innovation Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/90—Fusion polypeptide containing a motif for post-translational modification

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Pulmonology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN202211548024.1A 2015-06-05 2016-06-03 融合蛋白合成的方法和产品 Pending CN116199733A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB1509782.7A GB201509782D0 (en) 2015-06-05 2015-06-05 Methods and products for fusion protein synthesis
GB1509782.7 2015-06-05
PCT/GB2016/051640 WO2016193746A1 (en) 2015-06-05 2016-06-03 Methods and products for fusion protein synthesis
CN201680037511.8A CN108026148B (zh) 2015-06-05 2016-06-03 融合蛋白合成的方法和产品

Related Parent Applications (1)

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CN201680037511.8A Division CN108026148B (zh) 2015-06-05 2016-06-03 融合蛋白合成的方法和产品

Publications (1)

Publication Number Publication Date
CN116199733A true CN116199733A (zh) 2023-06-02

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Family Applications (2)

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CN202211548024.1A Pending CN116199733A (zh) 2015-06-05 2016-06-03 融合蛋白合成的方法和产品
CN201680037511.8A Active CN108026148B (zh) 2015-06-05 2016-06-03 融合蛋白合成的方法和产品

Family Applications After (1)

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CN201680037511.8A Active CN108026148B (zh) 2015-06-05 2016-06-03 融合蛋白合成的方法和产品

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US (1) US10526379B2 (enExample)
EP (1) EP3303374B1 (enExample)
JP (1) JP6883529B2 (enExample)
KR (1) KR102818627B1 (enExample)
CN (2) CN116199733A (enExample)
AU (1) AU2016272543B2 (enExample)
CA (1) CA2987821A1 (enExample)
DK (1) DK3303374T3 (enExample)
ES (1) ES2880336T3 (enExample)
GB (1) GB201509782D0 (enExample)
WO (1) WO2016193746A1 (enExample)

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GB202019817D0 (en) 2020-12-15 2021-01-27 Univ Oxford Innovation Ltd Ligand-binding polypeptides and uses thereof
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GB202104999D0 (en) 2021-04-08 2021-05-26 Univ Oxford Innovation Ltd Polypeptides that interact with peptide tags at loops or termini and uses thereof
CN113621031B (zh) * 2021-04-23 2023-05-05 中山大学 一种利用自发异肽键进行蛋白共价自组装的肽链接头的组合
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US20250129132A1 (en) * 2021-09-21 2025-04-24 University Of Washington Genetically encoded and exogenously triggered protein-protein ligation
CN113862235B (zh) * 2021-09-24 2024-07-05 苏州近岸蛋白质科技股份有限公司 一种嵌合酶及其在体外一步反应合成Cap0 mRNA的用途和方法
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CN116165377A (zh) * 2023-04-21 2023-05-26 常州伯仪生物科技有限公司 一种通过竞争elisa法进行标签蛋白定量的方法
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Also Published As

Publication number Publication date
GB201509782D0 (en) 2015-07-22
AU2016272543A1 (en) 2018-01-04
CA2987821A1 (en) 2016-12-08
US20180244730A1 (en) 2018-08-30
JP2018521640A (ja) 2018-08-09
ES2880336T3 (es) 2021-11-24
CN108026148A (zh) 2018-05-11
AU2016272543B2 (en) 2020-08-13
JP6883529B2 (ja) 2021-06-09
KR20180050640A (ko) 2018-05-15
EP3303374B1 (en) 2021-03-31
WO2016193746A1 (en) 2016-12-08
KR102818627B1 (ko) 2025-06-10
DK3303374T3 (da) 2021-07-05
BR112017026042A2 (pt) 2018-08-14
US10526379B2 (en) 2020-01-07
EP3303374A1 (en) 2018-04-11
CN108026148B (zh) 2022-12-30

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