KR102818627B1 - 융합 단백질 합성용 방법 및 생성물 - Google Patents

융합 단백질 합성용 방법 및 생성물 Download PDF

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KR102818627B1
KR102818627B1 KR1020187000488A KR20187000488A KR102818627B1 KR 102818627 B1 KR102818627 B1 KR 102818627B1 KR 1020187000488 A KR1020187000488 A KR 1020187000488A KR 20187000488 A KR20187000488 A KR 20187000488A KR 102818627 B1 KR102818627 B1 KR 102818627B1
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protein
peptide linker
amino acid
seq
lys
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KR20180050640A (ko
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마크 호왈쓰
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옥스포드 유니버시티 이노베이션 리미티드
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/90Fusion polypeptide containing a motif for post-translational modification

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Pulmonology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020187000488A 2015-06-05 2016-06-03 융합 단백질 합성용 방법 및 생성물 Active KR102818627B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1509782.7 2015-06-05
GBGB1509782.7A GB201509782D0 (en) 2015-06-05 2015-06-05 Methods and products for fusion protein synthesis
PCT/GB2016/051640 WO2016193746A1 (en) 2015-06-05 2016-06-03 Methods and products for fusion protein synthesis

Publications (2)

Publication Number Publication Date
KR20180050640A KR20180050640A (ko) 2018-05-15
KR102818627B1 true KR102818627B1 (ko) 2025-06-10

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Country Status (10)

Country Link
US (1) US10526379B2 (enExample)
EP (1) EP3303374B1 (enExample)
JP (1) JP6883529B2 (enExample)
KR (1) KR102818627B1 (enExample)
CN (2) CN116199733A (enExample)
AU (1) AU2016272543B2 (enExample)
DK (1) DK3303374T3 (enExample)
ES (1) ES2880336T3 (enExample)
GB (1) GB201509782D0 (enExample)
WO (1) WO2016193746A1 (enExample)

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GB202104104D0 (en) * 2021-03-24 2021-05-05 Liliumx Ltd Platform and method
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CN113621031B (zh) * 2021-04-23 2023-05-05 中山大学 一种利用自发异肽键进行蛋白共价自组装的肽链接头的组合
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CN113862235B (zh) * 2021-09-24 2024-07-05 苏州近岸蛋白质科技股份有限公司 一种嵌合酶及其在体外一步反应合成Cap0 mRNA的用途和方法
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WO2012127060A1 (fr) 2011-03-24 2012-09-27 Commissariat à l'énergie atomique et aux énergies alternatives Peptides aptes à former un complexe covalent et leurs utilisations
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Also Published As

Publication number Publication date
CN108026148B (zh) 2022-12-30
DK3303374T3 (da) 2021-07-05
ES2880336T3 (es) 2021-11-24
AU2016272543A1 (en) 2018-01-04
US10526379B2 (en) 2020-01-07
AU2016272543B2 (en) 2020-08-13
GB201509782D0 (en) 2015-07-22
JP6883529B2 (ja) 2021-06-09
EP3303374B1 (en) 2021-03-31
EP3303374A1 (en) 2018-04-11
JP2018521640A (ja) 2018-08-09
WO2016193746A1 (en) 2016-12-08
CA2987821A1 (en) 2016-12-08
BR112017026042A2 (pt) 2018-08-14
CN116199733A (zh) 2023-06-02
KR20180050640A (ko) 2018-05-15
US20180244730A1 (en) 2018-08-30
CN108026148A (zh) 2018-05-11

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