AU2016272543B2 - Methods and products for fusion protein synthesis - Google Patents

Methods and products for fusion protein synthesis Download PDF

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Publication number
AU2016272543B2
AU2016272543B2 AU2016272543A AU2016272543A AU2016272543B2 AU 2016272543 B2 AU2016272543 B2 AU 2016272543B2 AU 2016272543 A AU2016272543 A AU 2016272543A AU 2016272543 A AU2016272543 A AU 2016272543A AU 2016272543 B2 AU2016272543 B2 AU 2016272543B2
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amino acid
acid sequence
seq
set forth
protein
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AU2016272543A1 (en
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Mark Howarth
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Oxford University Innovation Ltd
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Oxford University Innovation Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/90—Fusion polypeptide containing a motif for post-translational modification

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Pulmonology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2016272543A 2015-06-05 2016-06-03 Methods and products for fusion protein synthesis Active AU2016272543B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1509782.7A GB201509782D0 (en) 2015-06-05 2015-06-05 Methods and products for fusion protein synthesis
GB1509782.7 2015-06-05
PCT/GB2016/051640 WO2016193746A1 (en) 2015-06-05 2016-06-03 Methods and products for fusion protein synthesis

Publications (2)

Publication Number Publication Date
AU2016272543A1 AU2016272543A1 (en) 2018-01-04
AU2016272543B2 true AU2016272543B2 (en) 2020-08-13

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AU2016272543A Active AU2016272543B2 (en) 2015-06-05 2016-06-03 Methods and products for fusion protein synthesis

Country Status (11)

Country Link
US (1) US10526379B2 (enExample)
EP (1) EP3303374B1 (enExample)
JP (1) JP6883529B2 (enExample)
KR (1) KR102818627B1 (enExample)
CN (2) CN116199733A (enExample)
AU (1) AU2016272543B2 (enExample)
CA (1) CA2987821A1 (enExample)
DK (1) DK3303374T3 (enExample)
ES (1) ES2880336T3 (enExample)
GB (1) GB201509782D0 (enExample)
WO (1) WO2016193746A1 (enExample)

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WO2020188346A1 (en) 2019-03-18 2020-09-24 Bio-Rad Abd Serotec Gmbh Antigen binding proteins
WO2020188356A1 (en) 2019-03-18 2020-09-24 Bio-Rad Abd Serotec Gmbh Antigen binding fragments conjugated to a plurality of fc isotypes and subclasses
WO2020188350A1 (en) 2019-03-18 2020-09-24 Bio-Rad Abd Serotec Gmbh Protection of spytag-containing periplasmic fusion proteins from protease tsp and ompt degradation
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US20240294585A1 (en) * 2020-04-13 2024-09-05 Colin David Gottlieb Modular binding proteins for extracellular vesicles and uses thereof
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CN113621031B (zh) * 2021-04-23 2023-05-05 中山大学 一种利用自发异肽键进行蛋白共价自组装的肽链接头的组合
GB202106361D0 (en) 2021-05-04 2021-06-16 Spybiotech Ltd Viral vectored vaccines
US20240240203A1 (en) 2021-05-04 2024-07-18 SpyBiotech Limited Adenoviral vectors and vaccines thereof
US20250129132A1 (en) * 2021-09-21 2025-04-24 University Of Washington Genetically encoded and exogenously triggered protein-protein ligation
CN113862235B (zh) * 2021-09-24 2024-07-05 苏州近岸蛋白质科技股份有限公司 一种嵌合酶及其在体外一步反应合成Cap0 mRNA的用途和方法
GB202117283D0 (en) 2021-11-30 2022-01-12 Univ Oxford Innovation Ltd Switchable polypeptide and its use for gentle affinity purification
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Also Published As

Publication number Publication date
GB201509782D0 (en) 2015-07-22
AU2016272543A1 (en) 2018-01-04
CA2987821A1 (en) 2016-12-08
US20180244730A1 (en) 2018-08-30
JP2018521640A (ja) 2018-08-09
ES2880336T3 (es) 2021-11-24
CN108026148A (zh) 2018-05-11
JP6883529B2 (ja) 2021-06-09
KR20180050640A (ko) 2018-05-15
EP3303374B1 (en) 2021-03-31
WO2016193746A1 (en) 2016-12-08
KR102818627B1 (ko) 2025-06-10
DK3303374T3 (da) 2021-07-05
CN116199733A (zh) 2023-06-02
BR112017026042A2 (pt) 2018-08-14
US10526379B2 (en) 2020-01-07
EP3303374A1 (en) 2018-04-11
CN108026148B (zh) 2022-12-30

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