CN115916748A - 作为用于治疗α-1抗胰蛋白酶缺乏症(AATD)的α-1抗胰蛋白酶调节剂的吲哚衍生物 - Google Patents

作为用于治疗α-1抗胰蛋白酶缺乏症(AATD)的α-1抗胰蛋白酶调节剂的吲哚衍生物 Download PDF

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CN115916748A
CN115916748A CN202180039837.5A CN202180039837A CN115916748A CN 115916748 A CN115916748 A CN 115916748A CN 202180039837 A CN202180039837 A CN 202180039837A CN 115916748 A CN115916748 A CN 115916748A
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alkyl
compound
pharmaceutically acceptable
compounds
cyano
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CN202180039837.5A
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Chinese (zh)
Inventor
S·吉鲁
M·P·克拉克
M·A·布罗德尼
P·M·努汉特
E·E·艾伦
R·F·小菲莫尼亚里
M·扎基
M·J·博伊德
D·D·戴宁格
H·张
H·邓
P·N·科利尔
B·麦克斯韦
N·D·华尔
S·M·荣金
J·王
Q·唐
G·S·弗莱明
P·琼斯
D·M·鲍彻
L·T·D·范宁
A·B·霍尔
D·J·赫利
M·A·小约翰逊
J·P·麦克斯韦
R·J·斯威特
T·L·塔普利
S·A·汤姆森
V·达马涅兹
K·M·科特雷尔
U·K·班达拉格
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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Publication of CN115916748A publication Critical patent/CN115916748A/zh
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CN202180039837.5A 2020-04-03 2021-04-02 作为用于治疗α-1抗胰蛋白酶缺乏症(AATD)的α-1抗胰蛋白酶调节剂的吲哚衍生物 Pending CN115916748A (zh)

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Application Number Priority Date Filing Date Title
US202063004717P 2020-04-03 2020-04-03
US63/004717 2020-04-03
PCT/US2021/025614 WO2021203023A1 (en) 2020-04-03 2021-04-02 Indole derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (aatd)

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CN115916748A true CN115916748A (zh) 2023-04-04

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