TWI908788B - α-１抗胰蛋白酶之調節劑 - Google Patents

α-１抗胰蛋白酶之調節劑

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Publication number
TWI908788B
TWI908788B TW110112401A TW110112401A TWI908788B TW I908788 B TWI908788 B TW I908788B TW 110112401 A TW110112401 A TW 110112401A TW 110112401 A TW110112401 A TW 110112401A TW I908788 B TWI908788 B TW I908788B
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Taiwan
Prior art keywords
alkyl
halogen
substituted
cyano
alkoxy
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TW110112401A
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English (en)
Chinese (zh)
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TW202208332A (zh
Inventor
賽門 吉羅克斯
麥可 菲利浦 克拉克
麥可 艾倫 布魯德尼
飛利 馬歇爾 努漢特
艾蜜莉 伊莉莎白 艾倫
羅伯特 法蘭西斯 二世 費摩格納里
馬里安 薩奇
麥可 約翰 波伊德
大衛 Ｄ 丹尼葛
張虎
鄧紅波
菲利浦 諾爾 柯立爾
布雷德 麥克斯威爾
納桑 Ｄ 沃爾
史堤芬 Ｍ 羅金
江 王
青 唐
葛伯里爾 席夢 弗雷明
彼得 瓊斯
黛安 瑪莉 保查爾
李維 Ｔ Ｄ 芬寧
艾美 Ｂ 荷爾
丹尼斯 詹姆士 赫里
麥克 阿瑟 二世 強森
約翰 派翠克 麥可斯威爾
莉貝卡 珍 史維特
提摩西 路易斯 塔普立
史蒂芬 Ａ 湯姆森
維洛尼克 德瑪格尼茲
凱文 麥克 柯特瑞爾
烏珀爾 基爾斯 班達瑞格
Original Assignee
美商維泰克斯製藥公司
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Publication of TW202208332A publication Critical patent/TW202208332A/zh
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
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TW110112401A 2020-04-03 2021-04-06 α-１抗胰蛋白酶之調節劑 TWI908788B (zh)

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TWI908788B true TWI908788B (zh) 2025-12-21

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