CN1156488C - 小诺霉素新衍生物、制备方法和医药用途 - Google Patents
小诺霉素新衍生物、制备方法和医药用途 Download PDFInfo
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- CN1156488C CN1156488C CNB01133701XA CN01133701A CN1156488C CN 1156488 C CN1156488 C CN 1156488C CN B01133701X A CNB01133701X A CN B01133701XA CN 01133701 A CN01133701 A CN 01133701A CN 1156488 C CN1156488 C CN 1156488C
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- micronomicin
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Abstract
Description
大肠99-3 | >128 | >128 | 64 | >128 | 128 | >128 | >128 | >128 | >128 |
大肠99-4 | >128 | >128 | 64 | >128 | >128 | >128 | >128 | >128 | >128 |
大肠99-5 | >128 | >128 | 64 | >128 | >128 | >128 | >128 | >128 | >128 |
大肠99-6 | >128 | >128 | 64 | >128 | >128 | >128 | >128 | >128 | >128 |
大肠99-7 | >128 | >128 | 64 | >128 | >128 | >128 | >128 | >128 | >128 |
大肠99-142 | 128 | >128 | 128 | >128 | >128 | >128 | >128 | >128 | >128 |
大肠99-147 | 128 | >128 | 8 | 128 | 64 | >128 | >128 | >128 | 32 |
大肠99-152 | >128 | >128 | 16 | >128 | >128 | >128 | >128 | >128 | >128 |
大肠99-160 | <0.06 | 1 | 0.25 | 1 | <0.06 | 128 | 64 | 64 | <0.06 |
大肠ATCC25922 | 0.5 | 16 | 4 | 0.06 | 0.25 | >128 | >128 | >128 | 1 |
克肺99-11 | <0.06 | 0.5 | <0.06 | 1 | <0.06 | 128 | 64 | 8 | <0.06 |
克肺99-17 | 128 | >128 | 128 | >128 | >128 | >128 | >128 | >128 | >128 |
克肺99-23 | 128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 |
克肺99-25 | 0.125 | 2 | 16 | 1 | <0.06 | 128 | >128 | >128 | 0.125 |
绿脓99-46 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 |
绿脓99-47 | 8 | >128 | >128 | 16 | 8 | >128 | >128 | >128 | 4 |
绿脓99-48 | 8 | >128 | >128 | 16 | 4 | >128 | >128 | >128 | 4 |
绿脓99-49 | 8 | >128 | >128 | 16 | 8 | >128 | >128 | >128 | 4 |
绿脓99-50 | 8 | >128 | >128 | 8 | 8 | >128 | >128 | >128 | 4 |
绿脓99-111 | 4 | 128 | >128 | 16 | 1 | >128 | >128 | >128 | 4 |
绿脓99-105 | 2 | 128 | 128 | 8 | 4 | >128 | >128 | >128 | 2 |
绿脓99-106 | 1 | 128 | 128 | 4 | 2 | >128 | >128 | >128 | 2 |
绿脓ATCC27853 | 2 | 64 | 32 | 1 | 1 | >128 | >128 | >128 | 8 |
阴沟99-3 | 128 | 128 | 64 | >128 | >128 | >128 | >128 | >128 | >128 |
阴沟99-4 | <0.06 | 0.5 | 0.125 | 0.5 | <0.06 | 64 | 64 | 4 | <0.06 |
阴沟99-9 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 |
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB01133701XA CN1156488C (zh) | 2001-12-18 | 2001-12-18 | 小诺霉素新衍生物、制备方法和医药用途 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB01133701XA CN1156488C (zh) | 2001-12-18 | 2001-12-18 | 小诺霉素新衍生物、制备方法和医药用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1397562A CN1397562A (zh) | 2003-02-19 |
CN1156488C true CN1156488C (zh) | 2004-07-07 |
Family
ID=4672034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB01133701XA Expired - Fee Related CN1156488C (zh) | 2001-12-18 | 2001-12-18 | 小诺霉素新衍生物、制备方法和医药用途 |
Country Status (1)
Country | Link |
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CN (1) | CN1156488C (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101225093B (zh) * | 2007-01-17 | 2011-04-27 | 山东轩竹医药科技有限公司 | 氨基糖苷类衍生物 |
EP3150617B1 (en) | 2007-11-21 | 2020-04-08 | Cipla USA, Inc. | Antibacterial aminoglycoside analogs |
CN101481397B (zh) * | 2009-01-23 | 2012-10-31 | 北京大学 | 一种新的卡那霉素a衍生物及其制备方法和用途 |
WO2010132757A2 (en) | 2009-05-15 | 2010-11-18 | Achaogen, Inc. | Antibacterial aminoglycoside analogs |
WO2010132759A1 (en) | 2009-05-15 | 2010-11-18 | Achaogen, Inc. | Antibacterial derivatives of dibekacin |
WO2010132768A1 (en) | 2009-05-15 | 2010-11-18 | Achaogen, Inc. | Antibacterial derivatives of sisomicin |
WO2010132760A1 (en) | 2009-05-15 | 2010-11-18 | Achaogen, Inc. | Antibacterial derivatives of tobramycin |
WO2010132765A2 (en) * | 2009-05-15 | 2010-11-18 | Achaogen, Inc. | Antibacterial aminoglycoside analogs |
WO2011044501A2 (en) * | 2009-10-09 | 2011-04-14 | Achaogen, Inc. | Antibacterial aminoglycoside analogs |
CN101928310B (zh) * | 2010-03-26 | 2012-09-05 | 常州方圆制药有限公司 | 3,2’,6’-三-N-乙酰基庆大霉素C1a的制备方法 |
EP2569324B9 (en) * | 2010-05-12 | 2018-03-28 | Rempex Pharmaceuticals, Inc. | Aminoglycoside derivatives |
CN102532215B (zh) * | 2010-12-24 | 2015-07-22 | 无锡济民可信山禾药业股份有限公司 | 一种氨基糖苷类化合物及其提取分离方法 |
CN102321131A (zh) * | 2011-06-03 | 2012-01-18 | 常州方圆制药有限公司 | 半合成氨基糖苷类抗生素、制备方法及其药物组合物 |
CN103665069B (zh) * | 2013-12-17 | 2016-05-11 | 无锡济民可信山禾药业股份有限公司 | 一种氨基糖苷类化合物及其提取分离方法 |
CN110066304B (zh) * | 2019-05-25 | 2022-08-16 | 无锡济煜山禾药业股份有限公司 | 1-n-乙基小诺霉素的合成方法 |
-
2001
- 2001-12-18 CN CNB01133701XA patent/CN1156488C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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CN1397562A (zh) | 2003-02-19 |
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Owner name: SICHUAN INDUSTRIAL INSTITUTE OF ANTIBIOTICS CO., Free format text: FORMER OWNER: SICHUAN INST OF ANTIBIOTIC INDUSTRY NATIONAL MEDICINE SUPERVISION AND MANAGEMENT Effective date: 20070803 |
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Effective date of registration: 20070803 Address after: 610051 No. 18 Banqiao Road, Chengdu, Sichuan, Chenghua District Patentee after: Sichuan Industrial institute of antibiotics Co., Ltd. Address before: 610051 No. 18 Banqiao Road, Chengdu, Sichuan, Chenghua District Patentee before: Sichuan Antobiotic Industry Research Inst., State Medicine Supervison & Administ |
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Granted publication date: 20040707 Termination date: 20111218 |