CN115089542A - Skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factor - Google Patents
Skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factor Download PDFInfo
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- CN115089542A CN115089542A CN202210640354.7A CN202210640354A CN115089542A CN 115089542 A CN115089542 A CN 115089542A CN 202210640354 A CN202210640354 A CN 202210640354A CN 115089542 A CN115089542 A CN 115089542A
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- skin
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- umbilical cord
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- 230000003712 anti-aging effect Effects 0.000 title claims abstract description 31
- 230000008439 repair process Effects 0.000 title claims abstract description 28
- 210000002901 mesenchymal stem cell Anatomy 0.000 title claims abstract description 27
- 239000000203 mixture Substances 0.000 title claims abstract description 26
- 210000003954 umbilical cord Anatomy 0.000 title claims abstract description 26
- 239000002994 raw material Substances 0.000 claims description 15
- 239000000843 powder Substances 0.000 abstract description 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract description 2
- 229920002674 hyaluronan Polymers 0.000 abstract description 2
- 229960003160 hyaluronic acid Drugs 0.000 abstract description 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 108010024636 Glutathione Proteins 0.000 abstract 1
- 241001122767 Theaceae Species 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 229960003180 glutathione Drugs 0.000 abstract 1
- 229920001432 poly(L-lactide) Polymers 0.000 abstract 1
- 150000008442 polyphenolic compounds Chemical class 0.000 abstract 1
- 235000013824 polyphenols Nutrition 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 description 6
- 230000032683 aging Effects 0.000 description 4
- 239000000284 extract Substances 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 239000002131 composite material Substances 0.000 description 3
- 230000009759 skin aging Effects 0.000 description 3
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000419 plant extract Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 241001474374 Blennius Species 0.000 description 1
- 235000005320 Coleus barbatus Nutrition 0.000 description 1
- 241000209490 Nymphaea Species 0.000 description 1
- 235000016791 Nymphaea odorata subsp odorata Nutrition 0.000 description 1
- 229930195210 Ophiopogon Natural products 0.000 description 1
- 244000248557 Ophiopogon japonicus Species 0.000 description 1
- 241000131459 Plectranthus barbatus Species 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 229920002385 Sodium hyaluronate Polymers 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229960001631 carbomer Drugs 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 239000008169 grapeseed oil Substances 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 229940069445 licorice extract Drugs 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/85—Polyesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/84—Products or compounds obtained by lyophilisation, freeze-drying
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factors, and relates to the technical field of skin care products. The skin anti-aging repair composition containing the umbilical cord mesenchymal stem cell factor comprises 5-15 parts of umbilical cord mesenchymal stem cell factor freeze-dried powder, 20-30 parts of hyaluronic acid, 12-18 parts of collagen, 0.3-0.7 part of poly-L-lactic acid, 1.6-3.5 parts of glutathione, 2-7 parts of tea polyphenol and 5-13 parts of procyanidine. The skin anti-aging repair composition has low cost and high repair efficiency on the skin, and can obviously improve the anti-aging performance of the skin.
Description
Technical Field
The invention belongs to the technical field of skin care products, and particularly relates to a skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factors.
Background
The skin is not only the outermost barrier of the human body against water loss and invasion by various pathogens, but also an important factor affecting personal image and social appeal. With the aging, the aging of the skin is inevitable, and the most visual phenomenon of the degeneration of the aging skin is aging, wrinkling and the like. In order to repair skin and delay skin aging, more and more functional skin care products are produced.
Chinese patent CN202210333249.9 discloses an efficient repairing anti-aging skin care product and a preparation method thereof, wherein the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass: 55-75 parts of anhydrous ions, 6-10 parts of glycerol, 1.5-3.2 parts of double-effect moisturizing factors, 0.82-0.86 part of hyaluronic acid, 2-4 parts of rose syrup, 0.13-0.17 part of hexapeptide, 2-8 parts of grape seed oil, 0.6-0.8 part of vitriol, 0.11-0.13 part of acetylated hexapeptide, 0.1-0.3 part of allantoin, 0.08-0.12 part of carbomer, 0.16-0.20 part of sodium hyaluronate and 0.15-0.17 part of triethanolamine. The patent technology shows that the skin care product can lighten melanin and brighten and whiten skin to a certain extent, but has not very obvious effect on resisting skin aging.
Umbilical cord Mesenchymal Stem Cells (MSCs) have a high differentiation potential and can be differentiated in multiple directions. It has wide clinical application prospect in tissue engineering aspects such as bones, cartilages, muscles, tendons, ligaments and the like. At present, some researchers also make umbilical cord mesenchymal stem cells into skin care products to delay skin aging. For example, chinese patent CN202010745728.2 discloses an anti-aging and repairing compound preparation containing stem cell factor and a preparation method thereof, and the patent technology comprises umbilical cord mesenchymal stem cell factor freeze-dried powder and plant extract. The plant extract comprises: coleus forskohlii root extract, licorice extract, water lily extract, ophiopogon root extract and austenitic seaweed extract. Although the composite preparation can obviously improve the anti-aging performance of skin, the dosage of the umbilical cord mesenchymal stem cell factor freeze-dried powder in the composite preparation is larger, so that the cost of the product is higher, the popularization and the promotion are difficult to realize, and meanwhile, the technical defect of longer period is caused when the composite preparation is used for repairing the skin.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides the skin anti-aging repair composition which is low in cost and short in skin repair period. The umbilical cord mesenchymal stem cell factor in the composition is low in dosage, the cost of the skin care product is reduced, and the composition also has high anti-aging and repairing effects.
The invention relates to a skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factors, which comprises the following raw materials in parts by weight:
in one embodiment, the skin anti-aging repair composition containing the umbilical cord mesenchymal stem cell factor comprises the following raw materials in parts by weight:
in one embodiment, the skin anti-aging repair composition containing the umbilical cord mesenchymal stem cell factor comprises the following raw materials in parts by weight:
in one embodiment, the skin anti-aging repair composition containing the umbilical cord mesenchymal stem cell factor comprises the following raw materials in parts by weight:
in one embodiment, the skin anti-aging repair composition containing the umbilical cord mesenchymal stem cell factor comprises the following raw materials in parts by weight:
compared with the prior art, the invention has the following beneficial effects:
the invention provides a skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factors, which has the advantages of low cost, high repair efficiency on skin and capability of obviously improving the anti-aging performance of skin.
Detailed Description
The present invention will be further described with reference to the following specific examples.
Example 1
A skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factors comprises the following raw materials in parts by weight:
example 2
A skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factors comprises the following raw materials in parts by weight:
example 3
A skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factors comprises the following raw materials in parts by weight:
example 4
A skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factors comprises the following raw materials in parts by weight:
a female of 35-50 years old is screened for testing, and the specific test method is that the skin anti-aging repair composition prepared in the embodiments 1-4 of the invention is mixed and then added with a proper amount of water to prepare mask slurry which is coated on the face for 20min and is coated for 3 times a week, and after the skin anti-aging repair composition is continuously used for two weeks, the facial stains of the tested female are obviously lightened, the wrinkles are lightened, and the skin is ruddy and glossy.
It should be noted that the above-mentioned embodiments are merely examples of the present invention, and it is obvious that the present invention is not limited to the above-mentioned embodiments, and other modifications are possible. All modifications directly or indirectly derivable by a person skilled in the art from the present disclosure are to be considered within the scope of the present invention.
Claims (5)
1. The skin anti-aging repair composition containing the umbilical cord mesenchymal stem cell factor is characterized by comprising the following raw materials in parts by weight:
2. the umbilical cord mesenchymal stem cell factor-containing skin anti-aging repair composition as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight:
3. the umbilical cord mesenchymal stem cell factor-containing skin anti-aging repair composition according to claim 1, which comprises the following raw materials in parts by weight:
4. the umbilical cord mesenchymal stem cell factor-containing skin anti-aging repair composition according to claim 1, which comprises the following raw materials in parts by weight:
5. the umbilical cord mesenchymal stem cell factor-containing skin anti-aging repair composition as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210640354.7A CN115089542A (en) | 2022-06-07 | 2022-06-07 | Skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210640354.7A CN115089542A (en) | 2022-06-07 | 2022-06-07 | Skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115089542A true CN115089542A (en) | 2022-09-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210640354.7A Pending CN115089542A (en) | 2022-06-07 | 2022-06-07 | Skin anti-aging repair composition containing umbilical cord mesenchymal stem cell factor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115089542A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116158990A (en) * | 2023-04-20 | 2023-05-26 | 包头市中心医院 | Composition for relieving sunken scars and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000060482A (en) * | 1998-06-11 | 2000-02-29 | Fancl Corp | Food composition |
| CN108186548A (en) * | 2018-03-19 | 2018-06-22 | 上海莱馥生命科学技术有限公司 | A kind of preparation method of the stem cell factor Essence with anti-aging effects |
| CN109125246A (en) * | 2017-06-26 | 2019-01-04 | 灏灵赛奥（天津）生物科技有限公司 | skin anti-aging composition |
| CN111840201A (en) * | 2020-07-29 | 2020-10-30 | 暨南大学 | Anti-aging and repairing composite preparation containing stem cell factor and preparation method thereof |
| CN113663059A (en) * | 2021-08-31 | 2021-11-19 | 苏州姑苏欣颜魅丽医疗美容诊所有限公司 | Anti-aging beauty injection and preparation method thereof |
| CN114159374A (en) * | 2021-12-10 | 2022-03-11 | 上海纳米技术及应用国家工程研究中心有限公司 | Preparation method, product and application of skin anti-aging mesenchymal stem cell exosome composition |
-
2022
- 2022-06-07 CN CN202210640354.7A patent/CN115089542A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000060482A (en) * | 1998-06-11 | 2000-02-29 | Fancl Corp | Food composition |
| CN109125246A (en) * | 2017-06-26 | 2019-01-04 | 灏灵赛奥（天津）生物科技有限公司 | skin anti-aging composition |
| CN108186548A (en) * | 2018-03-19 | 2018-06-22 | 上海莱馥生命科学技术有限公司 | A kind of preparation method of the stem cell factor Essence with anti-aging effects |
| CN111840201A (en) * | 2020-07-29 | 2020-10-30 | 暨南大学 | Anti-aging and repairing composite preparation containing stem cell factor and preparation method thereof |
| CN113663059A (en) * | 2021-08-31 | 2021-11-19 | 苏州姑苏欣颜魅丽医疗美容诊所有限公司 | Anti-aging beauty injection and preparation method thereof |
| CN114159374A (en) * | 2021-12-10 | 2022-03-11 | 上海纳米技术及应用国家工程研究中心有限公司 | Preparation method, product and application of skin anti-aging mesenchymal stem cell exosome composition |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116158990A (en) * | 2023-04-20 | 2023-05-26 | 包头市中心医院 | Composition for relieving sunken scars and preparation method thereof |
| CN116158990B (en) * | 2023-04-20 | 2023-06-30 | 包头市中心医院 | Composition for relieving sunken scars and preparation method thereof |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20220923 |
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