CN114981273A - 杂环酰胺类化合物、其可药用的盐及其制备方法和用途 - Google Patents

杂环酰胺类化合物、其可药用的盐及其制备方法和用途 Download PDF

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CN114981273A
CN114981273A CN202080066382.1A CN202080066382A CN114981273A CN 114981273 A CN114981273 A CN 114981273A CN 202080066382 A CN202080066382 A CN 202080066382A CN 114981273 A CN114981273 A CN 114981273A
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hydrogen
halogen
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CN114981273B (zh
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段文虎
耿美玉
张惠斌
谢作权
周金培
杨一飞
王玺渊
杨晓骏
张燕
胡兆雪
丁健
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China Pharmaceutical University
Shanghai Institute of Materia Medica of CAS
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Shanghai Institute of Materia Medica of CAS
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Abstract

一种通式(I)的杂环酰胺类化合物、其可药用的盐及其制备方法，以及所述化合物在制备治疗与STING活性相关的疾病的药物中的用途、在制备免疫佐剂中的用途、在制备激活STING药物中的用途。

Description

PCT国内申请，说明书已公开。

Claims (16)

  1. PCT国内申请，权利要求书已公开。
CN202080066382.1A 2019-09-19 2020-09-21 杂环酰胺类化合物、其可药用的盐及其制备方法和用途 Active CN114981273B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2019108910027 2019-09-19
CN201910891002.7A CN112521394A (zh) 2019-09-19 2019-09-19 杂环酰胺类化合物、其可药用的盐及其制备方法和用途
PCT/CN2020/116614 WO2021052501A1 (zh) 2019-09-19 2020-09-21 杂环酰胺类化合物、其可药用的盐及其制备方法和用途

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CN114981273B CN114981273B (zh) 2024-03-01

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CN202080066382.1A Active CN114981273B (zh) 2019-09-19 2020-09-21 杂环酰胺类化合物、其可药用的盐及其制备方法和用途

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US (1) US20220389025A1 (zh)
EP (1) EP4032890A1 (zh)
JP (1) JP2022549030A (zh)
KR (1) KR20220097388A (zh)
CN (2) CN112521394A (zh)
AU (1) AU2020348825B2 (zh)
BR (1) BR112022005182A2 (zh)
CA (1) CA3151776C (zh)
MX (1) MX2022003270A (zh)
WO (1) WO2021052501A1 (zh)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112521394A (zh) * 2019-09-19 2021-03-19 中国药科大学 杂环酰胺类化合物、其可药用的盐及其制备方法和用途
US20220388986A1 (en) * 2021-04-29 2022-12-08 Boehringer Ingelheim International Gmbh Heterocyclic compounds capable of activating sting
CN116332885A (zh) * 2023-02-13 2023-06-27 中国海洋大学 一种硝基杂环类sting激动剂及其制备方法和用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109071514A (zh) * 2016-04-07 2018-12-21 葛兰素史密斯克莱知识产权发展有限公司 用作蛋白质调节剂的杂环酰胺
WO2019069275A1 (en) * 2017-10-05 2019-04-11 Glaxosmithkline Intellectual Property Development Limited STING AGONIST ADMINISTRATION METHODS
WO2020028566A1 (en) * 2018-07-31 2020-02-06 Incyte Corporation Heteroaryl amide compounds as sting activators
CN112521394A (zh) * 2019-09-19 2021-03-19 中国药科大学 杂环酰胺类化合物、其可药用的盐及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110016025B (zh) * 2018-01-08 2021-08-06 成都先导药物开发股份有限公司 一种免疫调节剂

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109071514A (zh) * 2016-04-07 2018-12-21 葛兰素史密斯克莱知识产权发展有限公司 用作蛋白质调节剂的杂环酰胺
WO2019069275A1 (en) * 2017-10-05 2019-04-11 Glaxosmithkline Intellectual Property Development Limited STING AGONIST ADMINISTRATION METHODS
WO2020028566A1 (en) * 2018-07-31 2020-02-06 Incyte Corporation Heteroaryl amide compounds as sting activators
CN112521394A (zh) * 2019-09-19 2021-03-19 中国药科大学 杂环酰胺类化合物、其可药用的盐及其制备方法和用途

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AU2020348825B2 (en) 2023-12-21
US20220389025A1 (en) 2022-12-08
AU2020348825A1 (en) 2022-04-28
MX2022003270A (es) 2022-07-04
CA3151776C (en) 2024-04-09
BR112022005182A2 (pt) 2022-06-14
EP4032890A1 (en) 2022-07-27
CA3151776A1 (en) 2021-03-25
KR20220097388A (ko) 2022-07-07
CN114981273B (zh) 2024-03-01
JP2022549030A (ja) 2022-11-22
WO2021052501A1 (zh) 2021-03-25
CN112521394A (zh) 2021-03-19

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