CN114798581A - Cleaning device and cleaning method for sample analyzer - Google Patents
Cleaning device and cleaning method for sample analyzer Download PDFInfo
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- CN114798581A CN114798581A CN202210742760.4A CN202210742760A CN114798581A CN 114798581 A CN114798581 A CN 114798581A CN 202210742760 A CN202210742760 A CN 202210742760A CN 114798581 A CN114798581 A CN 114798581A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/10—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
- B08B3/102—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration with means for agitating the liquid
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/08—Cleaning involving contact with liquid the liquid having chemical or dissolving effect
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/02—Cleaning pipes or tubes or systems of pipes or tubes
- B08B9/027—Cleaning the internal surfaces; Removal of blockages
- B08B9/032—Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing
- B08B9/0321—Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing using pressurised, pulsating or purging fluid
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Abstract
The application provides a cleaning device and a cleaning method of a sample analyzer. The cleaning device of the application includes: the cleaning device comprises a driving part, a cleaning liquid supplementing part, a first control valve, a second control valve, a three-way piece and a part to be cleaned, wherein the driving part is used for driving cleaning liquid in the cleaning liquid supplementing part into the part to be cleaned, the same driving part is also used for sucking liquid in the part to be cleaned into a pipeline between the part to be cleaned and the driving part, the same driving part is also used for driving the cleaning liquid in the pipeline between the part to be cleaned and the driving part into the part to be cleaned, and therefore the cleaning of the part to be cleaned and the pipeline is realized through the cyclic motion of the cleaning liquid between the part to be cleaned and the pipeline between the part to be cleaned and the driving part. The cleaning device has the advantages of simple structure, low cost and good cleaning effect on the cleaning part and the related pipelines.
Description
Technical Field
The application relates to the technical field of medical instruments, in particular to a cleaning device and a cleaning method of a sample analyzer.
Background
The sample analyzer is a medical precision instrument and can be used for analyzing and measuring blood samples, and the general working process is as follows: sucking a quantitative sample, pumping the sample into a reaction tank according to a preset dilution ratio by using a quantitative reagent, and sampling and parameter measurement after uniform mixing and reaction in the reaction tank are completed. The sample analyzer needs to be filled with cleaning fluid to perform daily/periodic cleaning of the fluid path. So that the next measurement is not affected by the last measurement.
At present, some pipelines and reaction cells of some detection items need to be contacted with blood samples and strongly-adhesive reagents, such as latex reagents, fluorescent reagents and the like, so that the requirement on cleaning is high.
However, in the prior art, the cleaning effect of the sample analyzer is not good, and the problem of carrying pollution may be brought.
Disclosure of Invention
The application provides a cleaning device and a cleaning method of a sample analyzer, and aims to solve the technical problems that in the prior art, the cleaning effect of the sample analyzer is poor, and the carrying pollution problem is possibly caused.
In order to solve the technical problem, the application adopts a technical scheme that: there is provided a cleaning device for a sample analyzer, the cleaning device comprising: the cleaning device comprises a driving part, a cleaning liquid supplementing part, a first control valve, a second control valve, a three-way piece and a part to be cleaned, wherein the cleaning liquid supplementing part is connected with a first end of the first control valve, a second end of the first control valve is connected with a first interface of the three-way piece, a second interface of the three-way piece is connected with the driving part, the first control valve is used for controlling the communication and the closing between the cleaning liquid supplementing part and the first interface of the three-way piece, a third interface of the three-way piece is connected with a first end of the second control valve, a second end of the second control valve is connected with a first end of the part to be cleaned, the second control valve is used for controlling the communication and the closing between the third interface of the three-way piece and the part to be cleaned, the driving part is used for driving the cleaning liquid in the cleaning liquid supplementing part into the part to be cleaned, the same driving part is also used for sucking the liquid in the part to be cleaned into a pipeline between the part to be cleaned and the driving part, the same driving part is also used for driving the cleaning liquid in the pipeline between the part to be cleaned into the part to be cleaned, the cleaning liquid is circulated in the part to be cleaned and the pipeline between the part to be cleaned and the driving part through the driving part, so that the part to be cleaned and the pipeline between the part to be cleaned and the driving part are cleaned.
In order to solve the above technical problem, another technical solution adopted by the present application is: there is provided a method of cleaning a sample analyzer, the method of cleaning being based on the cleaning apparatus of any of the above embodiments, the method of cleaning comprising: injecting the cleaning liquid in the cleaning liquid supplementing part into the part to be cleaned through the driving part; sucking the liquid in the part to be cleaned into a pipeline between the part to be cleaned and the driving part through the same driving part; repeatedly injecting the cleaning liquid in the pipeline between the part to be cleaned and the driving part into the part to be cleaned through the driving part for multiple times and repeatedly sucking the liquid in the part to be cleaned into the pipeline between the part to be cleaned and the driving part through the same driving part for multiple times; and discharging the liquid in the part to be cleaned and the pipeline between the part to be cleaned and the driving part, so that the driving part realizes the circular motion of the cleaning liquid between the part to be cleaned and the pipeline between the part to be cleaned and the driving part, and further realizes the cleaning of the part to be cleaned and the pipeline between the part to be cleaned and the driving part.
The beneficial effect of this application is: in contrast to the state of the art, the cleaning device of the present application comprises: the cleaning device comprises a driving part, a cleaning liquid supplementing part, a first control valve, a second control valve, a three-way piece and a part to be cleaned, wherein the driving part is used for driving cleaning liquid in the cleaning liquid supplementing part into the part to be cleaned, the same driving part is also used for sucking liquid in the part to be cleaned into a pipeline between the part to be cleaned and the driving part, the same driving part is also used for driving the cleaning liquid in the pipeline between the part to be cleaned and the driving part into the part to be cleaned, and therefore the cleaning of the part to be cleaned and the pipeline between the part to be cleaned and the driving part can be realized through the driving part in the way that the cleaning liquid circularly moves in the part to be cleaned and the pipeline between the part to be cleaned and the driving part. The cleaning device can improve the cleaning effect, and has good cleaning effect on some reagents with strong adhesion, such as latex reagents, fluorescent reagents and the like.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:
FIG. 1 is a schematic block diagram of one embodiment of a cleaning device and detection assembly of a sample analyzer provided herein;
FIG. 2 is a schematic flow chart diagram of one embodiment of a method for cleaning a sample analyzer provided herein;
FIG. 3 is a flowchart illustrating an embodiment of step S11 in FIG. 2;
FIG. 4 is a flowchart illustrating an embodiment of step S13 in FIG. 2;
FIG. 5 is a schematic block diagram of another embodiment of a cleaning device and detection assembly of the sample analyzer provided herein;
FIG. 6 is a schematic flow chart diagram illustrating another embodiment of step S11 in FIG. 2;
fig. 7 is a schematic flowchart of another embodiment of step S13 in fig. 2.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
It should be noted that if directional indications (such as up, down, left, right, front, and back … …) are referred to in the embodiments of the present application, the directional indications are only used to explain the relative positional relationship between the components, the movement situation, and the like in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indications are changed accordingly.
In addition, if there is a description of "first", "second", etc. in the embodiments of the present application, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present application.
Referring to fig. 1, a sample analyzer 10 includes a cleaning device 101 and a detection assembly. The cleaning device 101 and the detection assembly will be described in detail below.
As shown in fig. 1, the cleaning apparatus 101 includes: a driving part 11, a cleaning liquid replenishing part 12, a first control valve 13, a second control valve 14, a three-way member 15 and a part to be cleaned 16.
Specifically, the cleaning liquid replenishing portion 12 is connected to a first end of the first control valve 13, a second end of the first control valve 13 is connected to a first port of the three-way member 15, a second port of the three-way member 15 is connected to the driving portion 11, and the first control valve 13 is configured to control communication and closing between the cleaning liquid replenishing portion 12 and the first port of the three-way member 15.
The third port of the three-way element 15 is connected to the first end of the second control valve 14, the second end of the second control valve 14 is connected to the first end of the portion to be cleaned 16, and the second control valve 14 is used for controlling the communication and closing between the third port of the three-way element 15 and the portion to be cleaned 16.
The driving portion 11 is used for driving the cleaning liquid in the cleaning liquid replenishing portion 12 into the portion-to-be-cleaned 16 to clean the portion-to-be-cleaned 16 with the cleaning liquid. Further, the same driving part 11 is also used for sucking the liquid in the part to be cleaned 16 into the pipeline between the part to be cleaned 16 and the driving part 11, and the same driving part 11 is also used for driving the cleaning liquid in the pipeline between the part to be cleaned 16 and the driving part 11 into the part to be cleaned 16, so as to realize the circulating motion of the cleaning liquid in the pipeline between the part to be cleaned 16 and the driving part 11 (such as the pipeline T1 and the pipeline T2 in fig. 1) through the driving part 11, and further realize the reciprocating cleaning of the part to be cleaned 16 and the pipeline between the part to be cleaned 16 and the driving part 11.
The cleaning device 101 is simple in structure, and can perform reciprocating cleaning on the portion to be cleaned 16 and the pipeline between the portion to be cleaned 16 and the driving portion 11, and by means of the mode, the cleaning effect can be improved, so that the reliability of the sample analyzer 10 is improved.
Further, the driving part 11 may include a positive and negative pressure source, wherein the positive and negative pressure source may be a syringe or a fixed displacement pump. Or the positive and negative pressure sources comprise a positive pressure source and a negative pressure source, wherein the positive pressure source and the negative pressure source are switched by the control valve.
Specifically, the second end of the first control valve 13 is connected to a positive and negative pressure source, and when the first end of the first control valve 13 is communicated with the second end of the first control valve 13, the positive and negative pressure source is used for sucking the cleaning liquid in the cleaning liquid replenishing portion 12, and when the first end of the second control valve 14 is communicated with the second end of the second control valve 14, the positive and negative pressure source is used for driving the sucked cleaning liquid into the portion-to-be-cleaned 16, in such a way that the positive and negative pressure source can drive the cleaning liquid in the cleaning liquid replenishing portion 12 into the portion-to-be-cleaned 16.
Further, when the first end of the second control valve 14 is communicated with the second end of the second control valve 14, the positive and negative pressure sources may be used to suck the liquid in the portion to be cleaned 16 into the pipeline between the portion to be cleaned 16 and the positive and negative pressure sources (for example, into the pipeline T1), and the positive and negative pressure sources may also be used to drive the cleaning liquid in the pipeline between the portion to be cleaned 16 and the positive and negative pressure sources into the portion to be cleaned 16, so that the cleaning effect of the portion to be cleaned 16 and the related pipelines can be enhanced through the sucking and discharging operations of the positive and negative pressure sources.
That is, the cleaning liquid can be injected into the portion-to-be-cleaned 16 through the line T2 and the line T1 by the positive and negative pressure sources which are also used to suck the liquid in the portion-to-be-cleaned 16 into the line between the portion-to-be-cleaned 16 and the positive and negative pressure sources, and the positive and negative pressure sources which are also used to drive the cleaning liquid in the line between the portion-to-be-cleaned 16 and the drive portion 11 into the portion-to-be-cleaned 16, so as to achieve the circulating movement of the cleaning liquid in the portions-to-be-cleaned 16 and the line between the portion-to-be-cleaned 16 and the positive and negative pressure sources by the positive and negative pressure sources, and thus to clean the portion-to-be-cleaned 16 and the line between the portion-to-be-cleaned 16 and the positive and negative pressure sources.
Further, as shown in fig. 1, the cleaning device 101 further includes a waste liquid collecting portion 17, the waste liquid collecting portion 17 is connected to the second end of the portion to be cleaned 16, and the waste liquid collecting portion 17 is used for discharging the liquid in the portion to be cleaned 16. The waste liquid collecting portion 17 may be connected to the second end of the portion-to-be-cleaned 16 through the control valve 171. The control valve 171 is used to control communication and closing between the waste liquid collecting portion 17 and the portion-to-be-cleaned 16. The waste liquid collecting portion 17 may include a negative pressure source for sucking out the liquid in the portion-to-be-cleaned 16. For example, after the sample is detected and before the cleaning apparatus 101 cleans the portion-to-be-cleaned 16, the waste liquid in the portion-to-be-cleaned 16 may be sucked out by the waste liquid collecting unit 17.
Further, the to-be-cleaned part 16 is configured to receive a sample and a reagent to form a to-be-detected liquid, and the driving part 11 is further configured to suck the to-be-detected liquid in the to-be-cleaned part 16 into a pipeline between the to-be-cleaned part 16 and the driving part 11 (for example, into a pipeline T1 as shown in fig. 1), and to inject the to-be-detected liquid in the pipeline between the to-be-cleaned part 16 and the driving part 11 into the to-be-cleaned part 16, so as to realize a circulating motion of the to-be-detected liquid in the pipeline between the to-be-cleaned part 16 and the driving part 11 through the driving part 11, and further realize uniform mixing of the to-be-detected liquid formed by the sample and the reagent. That is, the sample can be kneaded by sharing the components in the cleaning device 101, and in this way, it is not necessary to add another kneading component, and therefore, the structure of the sample analyzer 10 can be simplified, and the hardware cost can be saved. The means for adding the sample and the reagent to the portion to be cleaned 16 will be described below.
As shown in fig. 1, the sample analyzer 10 further includes a detection assembly, wherein the detection assembly includes a reagent addition assembly 18 and a sample addition assembly 19.
The sample adding unit 19 is used to add a sample to the portion to be cleaned 16. In particular, the sample addition assembly 19 may include a drive 191 and a sampling needle 192, the drive 191 being connected to the sampling needle 192. When a sample is to be detected, the sample is sucked up by the sampling needle 192, and the sample in the sampling needle 192 is injected into the portion to be cleaned 16 by the driving member 191. For example, the portion to be cleaned 16 includes a reaction cell, and a sample can be added to the reaction cell by the sample adding unit 19 and a reagent can be added to the reaction cell by the reagent adding unit 18, so that the reagent and the sample can be mixed in the reaction cell to form a liquid to be detected.
The reagent adding unit 18 may add different reagents to the portion to be cleaned 16 according to the items to be detected. For example, in the embodiment shown in FIG. 1, the reagent addition assembly 18 includes a hemolytic agent addition component (shown in FIG. 1 but not numbered) and an emulsion reagent addition component (shown in FIG. 1 but not numbered).
The hemolytic agent adding component includes a driving component 181 and a hemolytic agent storage portion 182, the driving component 181 is connected to the hemolytic agent storage portion 182, and the driving component 181 is used for injecting hemolytic agent in the hemolytic agent storage portion 182 into the portion to be cleaned 16. The driving member 181 may be connected to the hemolytic agent storage portion 182 through a three-way control valve 185, specifically, the driving member 181 is connected to a first end of the three-way control valve 185, a second end of the three-way control valve 185 is connected to the hemolytic agent storage portion 182, and a third end of the three-way control valve 185 is connected to the portion-to-be-cleaned 16. When the first end and the second end of the three-way control valve 185 are communicated, the driving member 181 is used to draw a predetermined amount of hemolytic agent from the hemolytic agent storage portion 182, and when the first end and the third end of the three-way control valve 185 are communicated, the driving member 181 injects the drawn hemolytic agent into the portion-to-be-washed 16.
The emulsion reagent adding part comprises a driving part 183 and an emulsion reagent storage part 184, wherein the driving part 183 is connected with the emulsion reagent storage part 184 and is used for injecting the emulsion reagent in the emulsion reagent storage part 184 into the part to be cleaned 16. The driving member 183 may be connected to the emulsion reagent storage unit 184 through a three-way control valve 186, specifically, the driving member 183 is connected to a first end of the three-way control valve 186, a second end of the three-way control valve 186 is connected to the emulsion reagent storage unit 184, and a third end of the three-way control valve 186 is connected to the to-be-cleaned unit 16. When the first end and the second end of the three-way control valve 186 are communicated, the driving unit 183 extracts a predetermined amount of the emulsion reagent from the emulsion reagent storage part 184, and when the first end and the third end of the three-way control valve 186 are communicated, the driving unit 183 injects the extracted emulsion reagent into the part to be cleaned 16.
Because the adhesion of latex reagent is very strong, the cleaning device 101 of the present application also has a better cleaning effect on reagents with very strong adhesion.
The driving units 181 and 183 may be syringes, quantitative pumps, etc. to add quantitative reagents to the portion to be cleaned 16. The quantitative sucking of the hemolytic agent and the latex reagent may be realized by a reagent needle, that is, the reagent needle moves into the portion to be cleaned 16 to add after sucking the reagent from the reagent bottle.
It is understood that the reagent adding assembly 18 can also be used for adding other reagents, such as fluorescent reagents, to the portion to be cleaned 16, and the arrangement can be selected according to the detection items of the sample, and is not limited in detail.
Based on the above-described cleaning apparatus 101, as shown in fig. 2, the method for cleaning a sample analyzer includes:
s11: the cleaning liquid in the cleaning liquid replenishing portion is injected into the portion to be cleaned by the driving portion.
S12: the liquid in the part to be cleaned is sucked into a pipeline between the part to be cleaned and the driving part through the same driving part.
S13: the cleaning liquid in the pipeline between the part to be cleaned and the driving part is injected into the part to be cleaned through the driving part repeatedly for multiple times, and the liquid in the part to be cleaned is sucked into the pipeline between the part to be cleaned and the driving part through the same driving part repeatedly for multiple times.
S14: and discharging the liquid in the part to be cleaned and the pipeline between the part to be cleaned and the driving part, so that the driving part realizes the circular motion of the cleaning liquid between the part to be cleaned and the pipeline between the part to be cleaned and the driving part, and further realizes the cleaning of the part to be cleaned and the pipeline.
In the present embodiment, step S13 may be understood as repeating step S11 and step S12, which are alternately performed a plurality of times. For example, after repeating the step S11 and the step S12 alternately performed N times, the step S11 is performed N +1 times: the cleaning liquid in the cleaning liquid replenishing portion is injected into the portion to be cleaned by the driving portion, and step S14 is finally performed. For another example, after repeating the steps S11 and S12 alternately executed N times, step S14 is finally executed: and discharging the liquid in the part to be cleaned and the pipeline between the part to be cleaned and the driving part. Wherein N is a natural number of 1 or more.
In the cleaning method, the to-be-cleaned part 16 and the pipeline between the to-be-cleaned part 16 and the driving part 11 can be cleaned in a reciprocating manner through the driving part 11, so that the cleaning effect can be improved, and particularly, the cleaning method has a good cleaning effect on a reagent with strong adhesion.
In a specific embodiment, when the driving portion 11 includes a positive and negative pressure source, and the second end of the first control valve 13 is connected to the positive and negative pressure source, as shown in fig. 3, the step of injecting the cleaning solution in the cleaning solution replenishing portion 12 into the portion to be cleaned 16 through the driving portion 11 includes:
s111: the first end of the first control valve is controlled to communicate with the second end of the first control valve.
S112: and sucking the cleaning liquid in the cleaning liquid replenishing part through positive and negative pressure sources.
The cleaning liquid in the cleaning liquid replenishing portion 12 can be sucked by the positive and negative pressure sources, and the sucked cleaning liquid is injected into the portion to be cleaned 16. In this way, the process of sucking and injecting the cleaning liquid is simple.
Further, as shown in fig. 4, the step of repeating the step of injecting the cleaning liquid in the pipeline between the portion to be cleaned 16 and the driving portion 11 into the portion to be cleaned 16 by the driving portion 11 a plurality of times and the step of sucking the liquid in the portion to be cleaned 16 into the pipeline between the portion to be cleaned 16 and the driving portion 11 by the same driving portion 11 a plurality of times includes:
s131: the first end of the second control valve is controlled to communicate with the second end of the second control valve.
S132: and repeatedly injecting the cleaning liquid sucked into the pipeline between the part to be cleaned and the driving part into the part to be cleaned through the positive and negative pressure sources.
S133: and repeatedly sucking the liquid in the part to be cleaned into a pipeline between the part to be cleaned and the driving part through the positive and negative pressure sources for a plurality of times.
That is, the positive and negative pressure sources can cause the cleaning liquid to flow back and forth in the portion to be cleaned 16 and the line between the portion to be cleaned 16 and the positive and negative pressure sources, and thus the cleaning effect can be enhanced, and the reliability of the sample analyzer 10 can be improved.
By way of example, in one particular embodiment, the detection process and the cleaning process of the sample analyzer 10 of the present application are as follows:
the method comprises the following steps: after the start of counting, the control valve 171 is opened to drain the portion-to-be-cleaned 16 through the waste liquid collecting portion 17;
step two: opening the three-way control valve 185, and controlling the driving member 181 to add the hemolytic agent to the portion-to-be-cleaned 16; the sampling needle 192 moves to the reaction cell, and the driving member 191 is controlled to add the blood sample to the portion to be cleaned 16; the second control valve 14 is opened, and the mixed solution of the hemolytic agent and the blood sample moves back and forth in the pipeline T1 and the part to be cleaned 16 through the driving part 11, so that the uniform mixing effect is achieved;
step three: opening the three-way control valve 186, and controlling the driving member 183 to add the latex reagent into the part to be cleaned 16; the second control valve 14 is opened, the mixed solution of the latex reagent, the hemolytic agent and the blood sample moves back and forth in the pipeline T1 and the part to be cleaned 16 through the driving part 11, the uniform mixing effect is achieved, and counting is started;
step four: after the counting is finished, the control valve 171 is opened to drain the portion to be cleaned 16;
step five: opening the first control valve 13, controlling the driving part 11 to suck the cleaning liquid, opening the second control valve 14, controlling the driving part 11 to add the cleaning liquid to the pipeline T1 and the part to be cleaned 16;
step six: the second control valve 14 is opened to control the driving part 11 so that the cleaning liquid is cleaned in the line T1 and the portion to be cleaned 16 in forward and reverse directions a plurality of times. The forward direction is the direction of the pipeline T1 toward the part 16 to be cleaned, and the reverse direction is the direction of the part 16 to be cleaned toward the pipeline T1.
Step seven: the control valve 171 is opened to drain the portion to be cleaned 16.
In the sample analyzer 10 of the present embodiment, the cleaning device 101 can perform reciprocating cleaning of the portion to be cleaned 16 and the relevant piping, and thus, the cleaning effect can be improved.
The present application further provides a sample analyzer, as shown in fig. 5, different from the cleaning device 101 in the embodiment shown in fig. 1, in the cleaning device 101 of the present embodiment, the driving portion 11 includes a first pressure driving portion 111 and a second pressure driving portion 112, the first pressure driving portion 111 is connected to the second port of the tee 15, and the second pressure driving portion 112 is connected to the cleaning solution supplementing portion 12.
When the first end of the first control valve 13 is communicated with the second end of the first control valve 13, and the first end of the second control valve 14 is communicated with the second end of the second control valve 14, the second pressure driving part 112 may be used to drive the cleaning liquid in the cleaning liquid replenishing part 12 into the part to be cleaned 16 to clean the part to be cleaned 16 by the cleaning liquid.
When the first end of the second control valve 14 is communicated with the second end of the second control valve 14, the first pressure driving part 111 may be configured to suck the liquid in the portion to be cleaned 16 into the pipeline between the portion to be cleaned 16 and the first pressure driving part 111, and the first pressure driving part 111 may be further configured to drive the cleaning liquid in the pipeline between the portion to be cleaned 16 and the first pressure driving part 111 into the portion to be cleaned 16, so that the cleaning liquid is circulated in the portion to be cleaned 16 and the pipeline between the portion to be cleaned 16 and the first pressure driving part 111 by the first pressure driving part 111, and then the portion to be cleaned 16 and the relevant pipeline are cleaned in a forward and backward manner, and by this way, the cleaning effect can be further enhanced.
The first pressure driving part 111 may be a syringe or a fixed displacement pump, and the second pressure driving part 112 may be a positive pressure source. The positive pressure source can drive the cleaning liquid in the cleaning liquid replenishing portion 12 into the portion to be cleaned 16 through the pipe T2 and the pipe T1, and the syringe or the fixed displacement pump can be used for sucking the liquid in the portion to be cleaned 16 into the pipe T1 and can also be used for driving the liquid in the pipe T1 into the portion to be cleaned 16, so as to positively and negatively clean the portion to be cleaned 16 and the pipe T1, thereby enhancing the cleaning effect.
It can be understood that, in the process of driving the liquid in the pipeline to the portion to be cleaned 16 by the first pressure driving portion 111, positive pressure can be added by the positive pressure source so that the liquid can enter the portion to be cleaned 16 more quickly, and in this way, the cleaning speed can be increased, thereby improving the working efficiency of the sample analyzer 10.
Further, as shown in fig. 2, in the present embodiment, the cleaning liquid replenishing portion 12 includes a cleaning liquid storage portion 121 and a cleaning liquid reservoir 122, the cleaning liquid storage portion 121 is connected to a first end of the cleaning liquid reservoir 122 and is configured to supply a predetermined amount of cleaning liquid to the cleaning liquid reservoir 122, the second pressure driving portion 112 is connected to a second end of the cleaning liquid reservoir 122, and a third end of the cleaning liquid reservoir 122 is connected to a first end of the first control valve 13. In this way, when the cleaning device 101 cleans the portion to be cleaned 16, the cleaning liquid can be injected into the cleaning liquid reservoir 122 through the cleaning liquid storage unit 121.
Specifically, when the first end of the first control valve 13 and the second end of the first control valve 13 are communicated, the second pressure driving part 112 may be used to drive the cleaning liquid in the cleaning liquid reservoir 122 to be input into the first pressure driving part 111. When the first end of the first control valve 13 and the second end of the first control valve 13 are communicated and the first end of the second control valve 14 and the second end of the second control valve 14 are communicated, the second pressure driving part 112 is used for driving the cleaning liquid in the cleaning liquid pool 122 into the portion to be cleaned 16 and a pipeline between the cleaning liquid pool 122 and the portion to be cleaned 16.
Further, as shown in fig. 5, the cleaning device 101 further includes a third control valve 123 and a fourth control valve 124, the cleaning liquid storage portion 121 is connected to a first end of the third control valve 123, a second end of the third control valve 123 is connected to a first end of the cleaning liquid reservoir 122, a first end of the fourth control valve 124 is connected to the second pressure driving portion 112, and a second end of the fourth control valve 124 is connected to a second end of the cleaning liquid reservoir 122. The third control valve 123 is used to control the communication and closing of the cleaning liquid storage portion 121 and the cleaning liquid reservoir 122. The fourth control valve 124 is used for controlling the communication and closing of the second pressure driving part 112 and the cleaning liquid pool 122.
Further, the first pressure driving portion 111 may be further configured to suck the liquid to be detected in the portion to be cleaned 16 into a pipeline between the portion to be cleaned 16 and the first pressure driving portion 111, and inject the liquid to be detected in the pipeline between the portion to be cleaned 16 and the first pressure driving portion 111 into the portion to be cleaned 16, so that the liquid to be detected circulates in the portion to be cleaned 16 and the pipeline between the portion to be cleaned 16 and the first pressure driving portion 111 through the first pressure driving portion 111, and the liquid to be detected is uniformly mixed.
In this embodiment, other structures in the sample analyzer 10, such as the structures of the waste liquid collecting portion 17, the reagent adding assembly 18, and the sample adding assembly 19, are the same as the corresponding structures in the embodiment shown in fig. 1, and are not described again here.
As shown in fig. 6, in a specific embodiment, the step of injecting the cleaning liquid in the cleaning liquid replenishing portion 12 into the portion to be cleaned 16 by the driving portion 11 includes:
s211: the first end of the first control valve is controlled to communicate with the second end of the first control valve, and the first end of the second control valve is controlled to communicate with the second end of the second control valve.
S212: the cleaning liquid in the cleaning liquid replenishing portion is driven into the portion to be cleaned by the second pressure driving portion.
That is, the cleaning liquid in the cleaning liquid replenishing portion 12 may be driven into the portion-to-be-cleaned 16 by the second pressure driving portion 112 to clean the portion-to-be-cleaned 16 by the cleaning liquid.
As shown in fig. 7, in a specific embodiment, the step of repeating the step of injecting the cleaning liquid in the pipeline between the portion to be cleaned 16 and the driving portion 11 into the portion to be cleaned 16 by the driving portion 11 for a plurality of times and the step of sucking the liquid in the portion to be cleaned 16 into the pipeline between the portion to be cleaned 16 and the driving portion 11 by the same driving portion 11 for a plurality of times comprises:
s221: the first end of the second control valve is controlled to communicate with the second end of the second control valve.
S222: the cleaning liquid sucked into the pipeline between the part to be cleaned and the first pressure driving part is repeatedly injected into the part to be cleaned through the first pressure driving part for a plurality of times.
S223: and the liquid in the part to be cleaned is sucked to the pipeline between the part to be cleaned and the first pressure driving part through the first pressure driving part for a plurality of times.
In this embodiment, the first pressure driving unit 111 may be used to positively and negatively flow the cleaning solution in the to-be-cleaned unit 16 and the pipeline between the to-be-cleaned unit 16 and the first pressure driving unit 111, so as to perform the reciprocating cleaning on the to-be-cleaned unit 16 and the related pipeline, thereby improving the cleaning effect and improving the reliability of the sample analyzer 10.
For example, in one particular embodiment, the testing process and the cleaning method of the sample analyzer 10 are as follows:
the method comprises the following steps: after the start of counting, the control valve 171 is opened to drain the portion to be cleaned 16.
Step two: opening the three-way control valve 185, and controlling the driving member 181 to add the hemolytic agent to the portion-to-be-cleaned 16; the sampling needle 192 moves to the part to be cleaned 16, and controls the driving member 191 to add the blood sample to the part to be cleaned 16; the second control valve 14 is opened, and the mixed solution of the hemolytic agent and the blood sample is moved back and forth in the pipeline T1 and the portion to be cleaned 16 by the first pressure driving portion 111, so as to achieve the uniform mixing effect;
step three: opening the three-way control valve 186, and controlling the driving member 183 to add the latex reagent into the part to be cleaned 16; the second control valve 14 is opened, and the mixed solution of the latex reagent, the hemolytic agent and the blood sample moves back and forth between the pipeline T1 and the part to be cleaned 16 through the driving part 11, so as to achieve the uniform mixing effect and start counting;
step four: after the counting is finished, the control valve 171 is opened to drain the portion to be cleaned 16;
step five: opening the first control valve 13, the second control valve 14 and the fourth control valve 124, and driving the cleaning liquid in the cleaning liquid reservoir 122 to the pipe T1 and the portion to be cleaned 16 by the second pressure driving portion 112;
step six: the second control valve 14 is opened to control the first pressure driving portion 111 so that the cleaning liquid is cleaned in the line T1 and the portion to be cleaned 16 in the forward and reverse directions a plurality of times. The forward direction is the direction of the pipeline T1 toward the part 16 to be cleaned, and the reverse direction is the direction of the part 16 to be cleaned toward the pipeline T1. Step seven: the control valve 171 is opened to drain the portion to be cleaned 16.
In the cleaning device 101 of this embodiment, the driving portion 11 includes two sub-driving portions, treats the cleaning portion 16 and treats the pipeline between the cleaning portion 16 and the driving portion 11 to carry out reciprocating cleaning through two sub-driving portions, and the cleaning effect is better, and can treat the sample in the cleaning portion 16 to mix through the first pressure driving portion 111, need not to add other mixing parts again to can practice thrift the hardware cost.
The above embodiments are merely examples and are not intended to limit the scope of the present disclosure, and all modifications, equivalents, and flow charts using the contents of the specification and drawings of the present disclosure, which are directly or indirectly applied to other related technical fields, are included in the scope of the present disclosure.
Claims (13)
1. A cleaning device for a sample analyzer, the cleaning device comprising:
a driving part, a cleaning liquid supplementing part, a first control valve, a second control valve, a three-way piece and a part to be cleaned,
wherein the cleaning liquid supplementing part is connected with a first end of the first control valve, a second end of the first control valve is connected with a first interface of the three-way piece, a second interface of the three-way piece is connected with the driving part, the first control valve is used for controlling the communication and the closing between the cleaning liquid supplementing part and the first interface of the three-way piece,
the third interface of the three-way part is connected with the first end of the second control valve, the second end of the second control valve is connected with the first end of the part to be cleaned, the second control valve is used for controlling the communication and the closing between the third interface of the three-way part and the part to be cleaned,
the driving part is used for driving the cleaning liquid in the cleaning liquid supplementing part into the part to be cleaned, the same driving part is also used for sucking the liquid in the part to be cleaned into a pipeline between the part to be cleaned and the driving part, and the same driving part is also used for driving the cleaning liquid in the pipeline between the part to be cleaned and the driving part into the part to be cleaned, so that the cleaning liquid circularly moves in the part to be cleaned and the pipeline between the part to be cleaned and the driving part through the same driving part, and further the cleaning of the part to be cleaned and the pipeline between the part to be cleaned and the driving part is realized.
2. The cleaning device according to claim 1, wherein the driving portion includes a positive and negative pressure source, the second end of the first control valve is connected to the positive and negative pressure source, the positive and negative pressure source is used for sucking the cleaning liquid in the cleaning liquid replenishing portion when the first end of the first control valve is communicated with the second end of the first control valve, and the positive and negative pressure source is used for driving the sucked cleaning liquid into the portion to be cleaned when the first end of the second control valve is communicated with the second end of the second control valve; when the first end of the second control valve is communicated with the second end of the second control valve, the positive and negative pressure sources are also used for driving the cleaning liquid in the pipeline between the part to be cleaned and the driving part into the part to be cleaned.
3. The cleaning device of claim 2, wherein the positive and negative pressure sources are syringes or metered pumps.
4. The cleaning device according to claim 1, wherein the driving portion includes a first pressure driving portion and a second pressure driving portion, the first pressure driving portion is connected to the second port of the three-way member, the second pressure driving portion is connected to the cleaning liquid replenishing portion,
the second pressure driving part is used for driving the cleaning liquid in the cleaning liquid supplementing part to the part to be cleaned when the first end of the first control valve is communicated with the second end of the first control valve and the first end of the second control valve is communicated with the second end of the second control valve,
when the first end of the second control valve is communicated with the second end of the second control valve, the first pressure driving part is used for sucking liquid in the part to be cleaned to a pipeline between the part to be cleaned and the first pressure driving part, and the first pressure driving part is also used for driving cleaning liquid in the pipeline between the part to be cleaned and the first pressure driving part to the part to be cleaned so as to realize the circulating motion of the cleaning liquid in the part to be cleaned and the pipeline between the part to be cleaned and the first pressure driving part through the first pressure driving part, thereby realizing the cleaning of the part to be cleaned and the pipeline between the part to be cleaned and the driving part.
5. The cleaning device according to claim 4, wherein the cleaning liquid replenishing portion includes a cleaning liquid storage portion and a cleaning liquid reservoir, the cleaning liquid storage portion is connected to a first end of the cleaning liquid reservoir and is configured to supply the cleaning liquid to the cleaning liquid reservoir, the second pressure driving portion is connected to a second end of the cleaning liquid reservoir, and a third end of the cleaning liquid reservoir is connected to a first end of the first control valve;
the first end of the first control valve is communicated with the second end of the first control valve, and the second pressure driving part is used for driving the cleaning liquid in the cleaning liquid pool to be input into the first pressure driving part;
the first end of the first control valve is communicated with the second end of the first control valve, and when the first end of the second control valve is communicated with the second end of the second control valve, the second pressure driving part is used for conveying the cleaning liquid in the cleaning liquid pool to the part to be cleaned and a pipeline between the cleaning liquid pool and the part to be cleaned.
6. The cleaning device of claim 5, further comprising a third control valve and a fourth control valve,
the cleaning liquid storage part is connected with the first end of the third control valve, the second end of the third control valve is connected with the first end of the cleaning liquid pool, the first end of the fourth control valve is connected with the second pressure driving part, and the second end of the fourth control valve is connected with the second end of the cleaning liquid pool.
7. The cleaning device of claim 4, wherein the first pressure drive is a syringe or a fixed displacement pump and the second pressure drive is a positive pressure source.
8. The cleaning device of claim 1, further comprising a waste liquid collecting portion connected to the second end of the portion to be cleaned and configured to discharge liquid in the portion to be cleaned.
9. The cleaning device according to claim 1, wherein the portion to be cleaned is configured to receive a sample and a reagent to form a liquid to be detected, and the driving portion is further configured to suck the liquid to be detected in the portion to be cleaned into a pipeline between the portion to be cleaned and the driving portion, and to inject the liquid to be detected in the pipeline between the portion to be cleaned and the driving portion into the portion to be cleaned, so as to implement, by the driving portion, a cyclic motion of the liquid to be detected between the portion to be cleaned and the pipeline between the portion to be cleaned and the driving portion, thereby implementing uniform mixing of the liquid to be detected formed by the sample and the reagent.
10. A method for cleaning a sample analyzer, based on the cleaning apparatus according to any one of claims 1 to 9, comprising:
injecting the cleaning liquid in the cleaning liquid supplementing part into the part to be cleaned through the driving part;
sucking the liquid in the part to be cleaned into a pipeline between the part to be cleaned and the driving part through the same driving part;
repeatedly injecting the cleaning liquid in the pipeline between the part to be cleaned and the driving part into the part to be cleaned through the driving part for multiple times and repeatedly sucking the liquid in the part to be cleaned into the pipeline between the part to be cleaned and the driving part through the same driving part for multiple times;
and discharging the liquid in the part to be cleaned and the pipeline between the part to be cleaned and the driving part, so that the cleaning liquid can circularly move between the part to be cleaned and the pipeline between the part to be cleaned and the driving part through the same driving part, and further the cleaning of the part to be cleaned and the pipeline between the part to be cleaned and the driving part can be realized.
11. The cleaning method of claim 10, wherein the drive portion includes a positive and negative pressure source, the second end of the first control valve is connected to the positive and negative pressure source,
the step of injecting the cleaning liquid in the cleaning liquid replenishing portion into the portion to be cleaned by the driving portion includes:
controlling a first end of the first control valve to communicate with a second end of the first control valve;
sucking the cleaning liquid in the cleaning liquid replenishing part through the positive and negative pressure sources;
the step of repeatedly injecting the cleaning liquid in the pipeline between the part to be cleaned and the driving part into the part to be cleaned through the driving part for multiple times and repeatedly sucking the liquid in the part to be cleaned into the pipeline between the part to be cleaned and the driving part through the same driving part for multiple times comprises the following steps:
controlling a first end of the second control valve to communicate with a second end of the second control valve;
repeatedly injecting the cleaning liquid sucked into the pipeline between the part to be cleaned and the driving part into the part to be cleaned through the positive and negative pressure sources for multiple times; and repeatedly sucking the liquid in the part to be cleaned into a pipeline between the part to be cleaned and the driving part through the positive and negative pressure sources for a plurality of times.
12. The cleaning method according to claim 10, wherein the driving portion includes a first pressure driving portion and a second pressure driving portion, the first pressure driving portion is connected to the second port of the three-way member, the second pressure driving portion is connected to the cleaning liquid replenishing portion,
the step of injecting the cleaning liquid in the cleaning liquid replenishing portion into the portion to be cleaned by the driving portion includes:
controlling a first end of the first control valve to communicate with a second end of the first control valve, and controlling a first end of the second control valve to communicate with a second end of the second control valve;
driving the cleaning liquid in the cleaning liquid replenishing portion into the portion to be cleaned by the second pressure driving portion;
the step of repeatedly injecting the cleaning liquid in the pipeline between the part to be cleaned and the driving part into the part to be cleaned through the driving part for multiple times and repeatedly sucking the liquid in the part to be cleaned into the pipeline between the part to be cleaned and the driving part through the same driving part for multiple times comprises the following steps:
controlling a first end of the second control valve to communicate with a second end of the second control valve;
repeatedly injecting the cleaning liquid sucked into the pipeline between the part to be cleaned and the first pressure driving part into the part to be cleaned through the first pressure driving part for a plurality of times;
and repeatedly sucking the liquid in the part to be cleaned to a pipeline between the part to be cleaned and the first pressure driving part through the first pressure driving part for a plurality of times.
13. The cleaning method according to claim 12, wherein the cleaning liquid replenishing portion includes a cleaning liquid storage portion and a cleaning liquid reservoir, the cleaning liquid storage portion being connected to a first end of the cleaning liquid reservoir and being adapted to supply the cleaning liquid to the cleaning liquid reservoir, the second pressure driving portion being connected to a second end of the cleaning liquid reservoir, a third end of the cleaning liquid reservoir being connected to a first end of the first control valve,
before the step of driving the cleaning liquid in the cleaning liquid replenishing portion to the portion to be cleaned by the second pressure driving portion, the cleaning method further includes:
and injecting a cleaning liquid into the cleaning liquid pool through the cleaning liquid storage part.
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| CN202210742760.4A CN114798581B (en) | 2022-06-28 | 2022-06-28 | Cleaning device and cleaning method for sample analyzer |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116037588A (en) * | 2023-01-17 | 2023-05-02 | 中元汇吉生物技术股份有限公司 | Classification pool cleaning system, method and analyzer |
| CN116106488A (en) * | 2023-04-13 | 2023-05-12 | 深圳市帝迈生物技术有限公司 | Sample analyzer |
Citations (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5147610A (en) * | 1990-06-15 | 1992-09-15 | Hitachi, Ltd. | Automatic analyzing apparatus |
| US20090052033A1 (en) * | 2005-04-20 | 2009-02-26 | Toshinori Fujiwara | Analyzer, method for cleaning photometry mechanism in such analyzer, and cleaning tool |
| JP2009285571A (en) * | 2008-05-29 | 2009-12-10 | Mitsubishi Electric Corp | Cleaning apparatus |
| EP2136210A1 (en) * | 2008-06-18 | 2009-12-23 | Horiba, Ltd. | Body fluid sample analyzer |
| US20100051060A1 (en) * | 2007-05-11 | 2010-03-04 | Beckman Coulter, Inc. | Nozzle cleaning method, nozzle cleaning device, and automatic analyzer |
| CN101869894A (en) * | 2009-04-24 | 2010-10-27 | 深圳迈瑞生物医疗电子股份有限公司 | Cleaning device, cleaning system, cleaning method and particle analyzer |
| CN209156557U (en) * | 2018-08-31 | 2019-07-26 | 深圳市帝迈生物技术有限公司 | A kind of detergent line, cleaning device and sample testing apparatus |
| CN210982226U (en) * | 2019-11-06 | 2020-07-10 | 湖南远璟生物技术有限公司 | Magnetic bead separation and cleaning device with mixed structure |
| US20200355676A1 (en) * | 2018-02-08 | 2020-11-12 | Chengdu Shen Mindray Medical Electronics Technology Research Institute Co., Ltd. | Fully automated chemiluminescence immunoassay analyzer |
| CN212410610U (en) * | 2019-11-30 | 2021-01-26 | 深圳市帝迈生物技术有限公司 | Specific protein detection module and blood detection instrument |
| CN112798345A (en) * | 2020-12-29 | 2021-05-14 | 深圳市科曼医疗设备有限公司 | Pre-dilution mode sample collection and distribution system, method and blood cell analyzer |
| CN112881712A (en) * | 2019-11-30 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Specific protein detection module, blood detection instrument and detection method |
| CN112881723A (en) * | 2019-11-30 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Blood detection device and blood detection method |
| CN114062661A (en) * | 2020-07-30 | 2022-02-18 | 深圳市帝迈生物技术有限公司 | Sample analyzer, sampling needle cleaning liquid path and cleaning method thereof |
| CN114062226A (en) * | 2020-07-31 | 2022-02-18 | 深圳市帝迈生物技术有限公司 | Liquid path device and sample analyzer |
| WO2022121495A1 (en) * | 2020-12-11 | 2022-06-16 | 深圳市帝迈生物技术有限公司 | Sample filling method, sample filling assembly, and sample analyzer |
| CN114632758A (en) * | 2020-12-16 | 2022-06-17 | 深圳市帝迈生物技术有限公司 | Cleaning device, liquid path cleaning method and sample analyzer |
-
2022
- 2022-06-28 CN CN202210742760.4A patent/CN114798581B/en active Active
Patent Citations (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5147610A (en) * | 1990-06-15 | 1992-09-15 | Hitachi, Ltd. | Automatic analyzing apparatus |
| US20090052033A1 (en) * | 2005-04-20 | 2009-02-26 | Toshinori Fujiwara | Analyzer, method for cleaning photometry mechanism in such analyzer, and cleaning tool |
| US20100051060A1 (en) * | 2007-05-11 | 2010-03-04 | Beckman Coulter, Inc. | Nozzle cleaning method, nozzle cleaning device, and automatic analyzer |
| JP2009285571A (en) * | 2008-05-29 | 2009-12-10 | Mitsubishi Electric Corp | Cleaning apparatus |
| EP2136210A1 (en) * | 2008-06-18 | 2009-12-23 | Horiba, Ltd. | Body fluid sample analyzer |
| CN101869894A (en) * | 2009-04-24 | 2010-10-27 | 深圳迈瑞生物医疗电子股份有限公司 | Cleaning device, cleaning system, cleaning method and particle analyzer |
| US20200355676A1 (en) * | 2018-02-08 | 2020-11-12 | Chengdu Shen Mindray Medical Electronics Technology Research Institute Co., Ltd. | Fully automated chemiluminescence immunoassay analyzer |
| CN209156557U (en) * | 2018-08-31 | 2019-07-26 | 深圳市帝迈生物技术有限公司 | A kind of detergent line, cleaning device and sample testing apparatus |
| CN210982226U (en) * | 2019-11-06 | 2020-07-10 | 湖南远璟生物技术有限公司 | Magnetic bead separation and cleaning device with mixed structure |
| CN212410610U (en) * | 2019-11-30 | 2021-01-26 | 深圳市帝迈生物技术有限公司 | Specific protein detection module and blood detection instrument |
| CN112881712A (en) * | 2019-11-30 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Specific protein detection module, blood detection instrument and detection method |
| CN112881723A (en) * | 2019-11-30 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Blood detection device and blood detection method |
| CN114062661A (en) * | 2020-07-30 | 2022-02-18 | 深圳市帝迈生物技术有限公司 | Sample analyzer, sampling needle cleaning liquid path and cleaning method thereof |
| CN114062226A (en) * | 2020-07-31 | 2022-02-18 | 深圳市帝迈生物技术有限公司 | Liquid path device and sample analyzer |
| WO2022121495A1 (en) * | 2020-12-11 | 2022-06-16 | 深圳市帝迈生物技术有限公司 | Sample filling method, sample filling assembly, and sample analyzer |
| CN114632758A (en) * | 2020-12-16 | 2022-06-17 | 深圳市帝迈生物技术有限公司 | Cleaning device, liquid path cleaning method and sample analyzer |
| CN112798345A (en) * | 2020-12-29 | 2021-05-14 | 深圳市科曼医疗设备有限公司 | Pre-dilution mode sample collection and distribution system, method and blood cell analyzer |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116037588A (en) * | 2023-01-17 | 2023-05-02 | 中元汇吉生物技术股份有限公司 | Classification pool cleaning system, method and analyzer |
| CN116106488A (en) * | 2023-04-13 | 2023-05-12 | 深圳市帝迈生物技术有限公司 | Sample analyzer |
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