CN101869894A - Cleaning device, cleaning system, cleaning method and particle analyzer - Google Patents
Cleaning device, cleaning system, cleaning method and particle analyzer Download PDFInfo
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- CN101869894A CN101869894A CN200910106775A CN200910106775A CN101869894A CN 101869894 A CN101869894 A CN 101869894A CN 200910106775 A CN200910106775 A CN 200910106775A CN 200910106775 A CN200910106775 A CN 200910106775A CN 101869894 A CN101869894 A CN 101869894A
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Abstract
The invention discloses a cleaning device, a cleaning system, a cleaning method and a particle analyzer, comprising a cleanout fluid module, a collection module and a control module, wherein the cleanout fluid module is used for driving cleanout fluid to clean a part to be cleaned, the collection module is used for collecting waste fluid after cleaning, and the control module is used for controlling the cleanout fluid module to clean the part to be cleaned back and forth. The cleanout fluid can carry out reciprocating motion on the part to be cleaned to change the flow rate and direction of the cleanout fluid, flushing force applied on the part to be cleaned is powerful so as to improve cleaning effect. By using the cleaning device, the cleaning system and the cleaning method, cleaning effect on cleaning dead angles caused by non-smooth transition in the part to be cleaned is obvious.
Description
Technical field
The invention relates to a kind of cleaning device, purging system, cleaning method and particle analyzer.
Background technology
Blood cell analyzer is used for analyzing, measuring blood sample, its general course of work is: with the blood sample suction analyzer of negative pressure source (as syringe) with certain volume, the analyzer inner utilization divide blood unit (as a minute blood valve) with blood sample quantitative be divided into many parts, use quantitative reagent then, according to predetermined thinner ratio each increment is originally squeezed into reaction tank, after reaction tank is finished mixing, reaction, minute each channel sample of blood valve is taken a sample and parameter measurement.In each measuring period, the device, the pipeline that all need blood sample is flowed through clean, and feasible measurement result next time is not subjected to the influence of this measurement.
As shown in Figures 1 and 2, in existing liquid road is cleaned, generally be with negative pressure source or positive pressure source, the control cleaning fluid flows to another direction by a direction (direction shown in the arrow among Fig. 1,2), thereby realizes the cleaning to the liquid road.In this kind cleaning method, can think that speed (comprising velocity magnitude and the velocity attitude) variation of cleaning fluid is less, cleaning fluid is also less to the flushing dynamics of cleaning position 1.In addition, structurally have the non-position that seamlessly transits 11 for some, cleaning performance is often not good.
Summary of the invention
Technical problem to be solved by this invention is, overcomes the deficiencies in the prior art, and a kind of cleaning device, purging system, cleaning method and particle analyzer that can improve cleaning performance is provided.
The technical solution adopted for the present invention to solve the technical problems is: a kind of cleaning device comprises: be used to drive cleaning fluid and treat the cleaning fluid module of cleaning the position and cleaning, be used to collect the collection module of the waste liquid after the cleaning and be used to control the cleaning fluid module and treat and clean the control module that the position is back and forth cleaned.
Described cleaning fluid module comprises the cleaning fluid pipeline and is used to utilize the pressure source of pressure-driven cleaning fluid, the cleaning fluid pipeline has first interface and second interface that is used to be connected position to be cleaned that is used to connect pressure source, and control module controlled pressure source drives cleaning fluid and moves back and forth.Described cleaning fluid module also comprises soda liquor container and control valve, first interface of pressure source, soda liquor container and cleaning fluid pipeline all is connected with control valve, control valve has first state and second state, and when first state, pressure source is communicated with soda liquor container; When second state, pressure source is communicated with first interface of cleaning fluid pipeline.Described pressure source is a syringe, and control valve is a three-way magnetic valve, and control device is to be connected with syringe and to control the reciprocating stepper motor of syringe.
Described cleaning fluid module and collection module all have two, be respectively be used for cleaning the first cleaning fluid module and first collection module corresponding at position to be cleaned with it at first direction, the second cleaning fluid module that is used for cleaning in second direction position to be cleaned reaches and its second corresponding collection module, first direction and second direction are reverse.
A kind of purging system comprises position to be cleaned and cleaning device, and the cleaning fluid module all is connected with this position to be cleaned with collection module.A kind of particle analyzer comprises purging system.Particle analyzer is a blood cell analyzer, and position to be cleaned is device or the pipeline that blood sample is flowed through.
A kind of cleaning method comprises the steps: to be used for treating the first step that the cleaning position is cleaned on first direction; Be used for the reverse second direction of first direction on treat and clean second step that the position is cleaned.
A kind of cleaning device comprises that being used to drive cleaning fluid treats to clean the cleaning fluid module of cleaning at the position and be used to control the cleaning fluid module and treat and clean the control module that the position is back and forth cleaned.
The invention has the beneficial effects as follows that cleaning fluid can move back and forth at position to be cleaned, makes the direction of cleaning fluid that variation take place, the flushing ability that position to be cleaned is subjected to will be bigger, improved cleaning performance; There is non-seamlessly transitting and when causing cleaning the dead angle, cleaning performance is particularly remarkable for position to be cleaned.
Description of drawings
Fig. 1 is the schematic diagram that has now when first direction cleans cleaning the position;
Fig. 2 is the schematic diagram that has now when second direction is cleaned cleaning the position;
Fig. 3 is the structural representation of the first embodiment purging system;
Fig. 4 is the schematic diagram of movement locus of the syringe of reflection first embodiment;
Fig. 5 is the structural representation of the second embodiment purging system.
The specific embodiment
Purging system comprises position to be cleaned and cleaning device, and cleaning device comprises the cleaning fluid module that is used to drive cleaning fluid and cleans position to be cleaned, be used to collect the collection module of the waste liquid after the cleaning and be used to control the control module that the cleaning fluid module is back and forth cleaned.The cleaning fluid pipeline that the cleaning fluid module comprises the soda liquor container that is used to deposit cleaning fluid, be used to utilize the pressure source that the pressure-driven cleaning fluid flows and be used for flowing for cleaning fluid, the two ends of cleaning fluid pipeline connect pressure source and position to be cleaned respectively.The cleaning fluid module can also be provided with control valve, control device and the control valve control connection of the mobile state of control cleaning fluid.The collection pipeline that collection module comprises waste fluid container and is used for flowing for waste liquid, the two ends of collecting pipeline connect position to be cleaned and waste fluid container respectively, and the waste liquid after the cleaning flows into waste fluid container by collecting pipeline.Collection module can also be provided with control valve, control device and this control valve control connection of control waste liquid flow regime.Control device realizes treating the reciprocal cleaning of cleaning the position by the controlled pressure source.
Be example explanation purging system now, as shown in Figures 3 and 4 with the branch blood valve in the blood cell analyzer.Position to be cleaned 34 is for dividing a blood valve, and pressure source 30 be a syringe, and control valve 31 is a three-way magnetic valve, and control device is a stepper motor, and stepper motor is connected with syringe and controls the syringe reciprocating motion.First interface of soda liquor container 32, syringe and cleaning fluid pipeline 33 all is connected with three-way magnetic valve, and second interface of cleaning fluid pipeline 33 is communicated with the inlet that divides the blood valve.Collection module comprises to be collected pipeline 37, waste fluid container 39 and is located at sampling needle 35 and shut-off valve 38 on this collections pipeline 37, divides the liquid outlet of blood valve to be communicated with collection pipeline 37.This collection module also can be provided with the swab 36 that the outer wall to sampling needle 35 cleans.When a minute blood valve is cleaned, at first control three-way magnetic valve and syringe, suck cleaning fluid to syringe inside from soda liquor container 32, then, cooperate, cleaning fluid is pushed the associated pipe of branch blood valve by three-way magnetic valve and syringe, and in minute associated pipe of blood valve, move back and forth by the reciprocating motion of syringe control cleaning fluid, in this reciprocating process, shut-off valve 38 cuts out, and whole collection pipeline 37 is disconnected.After back and forth cleaning is finished, open shut-off valve 38, the waste liquid after the cleaning enters waste fluid container 39 through sampling needle 35, shut-off valve 38 in turn.In entire work process, the movement locus of syringe as shown in Figure 4.Under identical condition, after process is back and forth cleaned, the number of residue blood cell is about 20 in the pipeline of branch blood valve, and after the existing unidirectional cleaning, the number that remains blood cell is about 220.During waste collection, can extract, also can directly utilize the pressure source of cleaning fluid module by the malleation or the negative pressure extracting device of collection module self.In the present embodiment, pressure source can be syringe, also can be constant displacement pump, liquid storage tank or the waste drains pump etc. of other negative pressure or positive pressure-controlled.Cleaning fluid can be a cleaning fluid special-purpose in the blood cell analyzer, also can be other reagent that can flow through and be cleaned the position and can play the cleaning action of liquid road.
As shown in Figure 5, it is another kind of embodiment.The cleaning fluid module has two, is respectively to clean the first cleaning fluid module 4 at position 34 to be cleaned and the second cleaning fluid module 6 of cleaning position to be cleaned in second direction at first direction.Collection module also has two, is respectively first collection module 5 corresponding with the first cleaning fluid module 4 and second collection module 7 corresponding with the second cleaning fluid module 6.First and second cleaning fluid module includes soda liquor container 41, shut-off valve 42 and cleaning fluid pipeline 43, and first and second collection module includes waste fluid container 61, shut-off valve 62 and waste liquid pipeline 63.The first cleaning fluid module 4 and second collection module 7 are connected the inlet at position 34 to be cleaned simultaneously by control valve, and the second cleaning fluid module 6 and first collection module 5 are connected the liquid outlet at position 34 to be cleaned simultaneously by control valve.During cleaning, at first treat cleaning position 34 by the first cleaning fluid module 4 at first direction and clean, the waste liquid after the cleaning is collected by first collection module 5; Then, open the second cleaning fluid module 6 again, treat the cleaning position in second direction and clean, the waste liquid after the cleaning is collected by second collection module 7, and first direction and second direction are reverse.Certainly, position to be cleaned also can have two pairs of openings that pass through for liquid, and each module connects an opening respectively, controls first and second cleaning fluid module by control device and treats on first and second direction and clean the position and clean.
Purging system can be applied on the particle analyzer, as is used in the device that realization is flowed through to blood sample on the blood cell analyzer, the cleaning that the position is cleaned in the pipeline wait.Certainly, purging system also can be applicable to other and need utilize on the instrument and equipment that liquid cleans.
A kind of cleaning method comprises the steps: to be used for treating the first step that the cleaning position is cleaned at first direction; Be used for the reverse second direction of first direction on treat and clean second step that the position is cleaned.First step is carried out second step after can carrying out repeatedly continuously again; Also can be that the first step and second step hocket.First step can carry out simultaneously with second step, promptly treats the cleaning position from opposite both direction simultaneously and cleans; First step also can carry out with the second step timesharing, promptly cleans in a direction earlier again and oppositely cleans.First step can be different with cleaning fluid kind or cleaning fluid source in second step, and for the first step or second step repeatedly carried out, each cleaning fluid kind or cleaning fluid source also can be different.This cleaning method can be applied on the particle analyzer, also can be applied in other and need utilize on the instrument and equipment that cleaning fluid cleans.
Above content be in conjunction with concrete preferred implementation to further describing that the present invention did, can not assert that concrete enforcement of the present invention is confined to these explanations.For the general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace, all should be considered as belonging to protection scope of the present invention.
Claims (10)
1. cleaning device is characterized in that: comprising: be used to drive cleaning fluid and treat the cleaning fluid module of cleaning the position and cleaning, be used to collect the collection module of the waste liquid after the cleaning and be used to control the control module that described cleaning fluid module is back and forth cleaned described position to be cleaned.
2. cleaning device according to claim 1, it is characterized in that: described cleaning fluid module comprises the cleaning fluid pipeline and is used to utilize the pressure source of the described cleaning fluid of pressure-driven, described cleaning fluid pipeline has first interface and second interface that is used to be connected described position to be cleaned that is used to connect described pressure source, and described control module is controlled described pressure source and driven described cleaning fluid reciprocating motion.
3. cleaning device according to claim 2, it is characterized in that: described cleaning fluid module also comprises soda liquor container and control valve, first interface of described pressure source, soda liquor container and cleaning fluid pipeline all is connected with described control valve, described control valve has first state and second state, when first state, described pressure source is communicated with described soda liquor container; When second state, described pressure source is communicated with first interface of described cleaning fluid pipeline.
4. cleaning device according to claim 3 is characterized in that: described pressure source is a syringe, and described control valve is a three-way magnetic valve, and described control device is for being connected with described syringe and controlling the reciprocating stepper motor of described syringe.
5. cleaning device according to claim 1, it is characterized in that: described cleaning fluid module and collection module all have two, be respectively be used for cleaning the first cleaning fluid module and first collection module corresponding at described position to be cleaned with it at first direction, the second cleaning fluid module that is used for cleaning in second direction described position to be cleaned reaches and its second corresponding collection module, first direction and second direction are reverse.
6. a purging system comprises position to be cleaned, it is characterized in that: comprise that also as any described cleaning device in the claim 1 to 5, described cleaning fluid module all is connected with described position to be cleaned with described collection module.
7. a particle analyzer is characterized in that: comprise purging system as claimed in claim 6.
8. particle analyzer according to claim 7 is characterized in that: described particle analyzer is a blood cell analyzer, and described position to be cleaned is device or the pipeline that blood sample is flowed through.
9. a cleaning method is characterized in that: comprise the steps:
Be used on first direction, treating the first step that the cleaning position is cleaned; Be used for the reverse second direction of first direction on second step that described position to be cleaned is cleaned.
10. a cleaning device is characterized in that: comprise that being used to drive cleaning fluid treats the cleaning fluid module of cleaning at the cleaning position and be used to control the control module that described cleaning fluid module is back and forth cleaned described position to be cleaned.
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| CN200910106775.6A CN101869894B (en) | 2009-04-24 | 2009-04-24 | Clean device, purging system, cleaning method and particle analyzer |
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| CN200910106775.6A CN101869894B (en) | 2009-04-24 | 2009-04-24 | Clean device, purging system, cleaning method and particle analyzer |
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| CN101869894A true CN101869894A (en) | 2010-10-27 |
| CN101869894B CN101869894B (en) | 2016-11-09 |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105562389A (en) * | 2014-10-16 | 2016-05-11 | 北京普利生仪器有限公司 | Sampling needle cleaning system and sampling needle cleaning method |
| CN105880204A (en) * | 2016-05-06 | 2016-08-24 | 南京医科大学 | Fast cleaning method for gold-bearing matrix detection plate for cell analyzer |
| CN106483316A (en) * | 2016-08-31 | 2017-03-08 | 武汉明德生物科技股份有限公司 | Full-automatic immune quantitative analyser fluid path control system and its purging method |
| CN109716142A (en) * | 2016-09-21 | 2019-05-03 | 株式会社日立高新技术 | Automatic analysing apparatus |
| CN110434128A (en) * | 2018-05-02 | 2019-11-12 | 深圳开立生物医疗科技股份有限公司 | Sampling needle cleaning device and cleaning method |
| CN113042116A (en) * | 2017-12-30 | 2021-06-29 | 深圳迈瑞生物医疗电子股份有限公司 | Waste liquid pool, waste liquid treatment device and sample analyzer |
| CN113311163A (en) * | 2020-02-26 | 2021-08-27 | 深圳迈瑞生物医疗电子股份有限公司 | Cleaning method of detection pool |
| CN114160529A (en) * | 2021-10-29 | 2022-03-11 | 常州必达科生物科技有限公司 | Flow-type pool cleaning system and method |
| CN114632758A (en) * | 2020-12-16 | 2022-06-17 | 深圳市帝迈生物技术有限公司 | Cleaning device, liquid path cleaning method and sample analyzer |
| CN114798581A (en) * | 2022-06-28 | 2022-07-29 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for sample analyzer |
| CN114798614A (en) * | 2022-06-28 | 2022-07-29 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for sample analyzer and sample analyzer |
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| CN2032512U (en) * | 1988-05-03 | 1989-02-15 | 北京师范大学 | Test tube washing device |
| DE3902366C2 (en) * | 1989-01-27 | 1999-05-12 | Jens Pannenborg | Process for operating consumer pipe systems or circulation systems and device for carrying out this process |
| CN2075112U (en) * | 1990-10-04 | 1991-04-17 | 山东省立医院 | Moveable auto-acid-oscillating bottle washing machine |
| JP3176583B2 (en) * | 1998-08-31 | 2001-06-18 | 株式会社プレテック | Reciprocating pump for transferring liquid, control method therefor, and cleaning device |
| CN2373198Y (en) * | 1999-04-28 | 2000-04-12 | 吴元华 | On-line preventing and descaling device |
| CN101246180B (en) * | 2007-02-16 | 2012-11-21 | 深圳迈瑞生物医疗电子股份有限公司 | Blood cell analyzer cleaning agent automatic filling method and device |
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| CN105562389A (en) * | 2014-10-16 | 2016-05-11 | 北京普利生仪器有限公司 | Sampling needle cleaning system and sampling needle cleaning method |
| CN105880204A (en) * | 2016-05-06 | 2016-08-24 | 南京医科大学 | Fast cleaning method for gold-bearing matrix detection plate for cell analyzer |
| CN105880204B (en) * | 2016-05-06 | 2017-12-01 | 南京医科大学 | Rapid Cleaning method for cytoanalyze with the drafting board of quality inspection containing auri |
| CN106483316A (en) * | 2016-08-31 | 2017-03-08 | 武汉明德生物科技股份有限公司 | Full-automatic immune quantitative analyser fluid path control system and its purging method |
| CN109716142B (en) * | 2016-09-21 | 2023-06-27 | 株式会社日立高新技术 | Automatic analysis device |
| CN109716142A (en) * | 2016-09-21 | 2019-05-03 | 株式会社日立高新技术 | Automatic analysing apparatus |
| CN113042116A (en) * | 2017-12-30 | 2021-06-29 | 深圳迈瑞生物医疗电子股份有限公司 | Waste liquid pool, waste liquid treatment device and sample analyzer |
| CN110434128A (en) * | 2018-05-02 | 2019-11-12 | 深圳开立生物医疗科技股份有限公司 | Sampling needle cleaning device and cleaning method |
| CN113311163A (en) * | 2020-02-26 | 2021-08-27 | 深圳迈瑞生物医疗电子股份有限公司 | Cleaning method of detection pool |
| CN113311163B (en) * | 2020-02-26 | 2024-04-12 | 深圳迈瑞生物医疗电子股份有限公司 | Cleaning method of detection pool |
| CN114632758A (en) * | 2020-12-16 | 2022-06-17 | 深圳市帝迈生物技术有限公司 | Cleaning device, liquid path cleaning method and sample analyzer |
| CN114632758B (en) * | 2020-12-16 | 2024-04-09 | 深圳市帝迈生物技术有限公司 | Cleaning device, liquid path cleaning method and sample analyzer |
| CN114160529A (en) * | 2021-10-29 | 2022-03-11 | 常州必达科生物科技有限公司 | Flow-type pool cleaning system and method |
| CN114798581B (en) * | 2022-06-28 | 2022-10-28 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for sample analyzer |
| CN114798614A (en) * | 2022-06-28 | 2022-07-29 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for sample analyzer and sample analyzer |
| CN114798581A (en) * | 2022-06-28 | 2022-07-29 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for sample analyzer |
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| CN101869894B (en) | 2016-11-09 |
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Application publication date: 20101027 Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd. Assignor: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS Co.,Ltd. Contract record no.: X2022440020009 Denomination of invention: Cleaning device, cleaning system, cleaning method and particle analyzer Granted publication date: 20161109 License type: Common License Record date: 20220804 |
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