CN110434128A - Sampling needle cleaning device and cleaning method - Google Patents

Sampling needle cleaning device and cleaning method Download PDF

Info

Publication number
CN110434128A
CN110434128A CN201810411541.1A CN201810411541A CN110434128A CN 110434128 A CN110434128 A CN 110434128A CN 201810411541 A CN201810411541 A CN 201810411541A CN 110434128 A CN110434128 A CN 110434128A
Authority
CN
China
Prior art keywords
sampling needle
cleaning
service sink
needle
cleaning solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201810411541.1A
Other languages
Chinese (zh)
Other versions
CN110434128B (en
Inventor
喻小磊
白新梅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sonoscape Medical Corp
Original Assignee
Sonoscape Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sonoscape Medical Corp filed Critical Sonoscape Medical Corp
Priority to CN201810411541.1A priority Critical patent/CN110434128B/en
Publication of CN110434128A publication Critical patent/CN110434128A/en
Application granted granted Critical
Publication of CN110434128B publication Critical patent/CN110434128B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/02Cleaning pipes or tubes or systems of pipes or tubes
    • B08B9/023Cleaning the external surface
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/02Cleaning pipes or tubes or systems of pipes or tubes
    • B08B9/027Cleaning the internal surfaces; Removal of blockages
    • B08B9/032Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing
    • B08B9/0321Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing using pressurised, pulsating or purging fluid

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a kind of sampling needle cleaning device and cleaning methods, the device includes service sink, needle point cleaning module and sampling needle inner wall washing module, wherein, the orifice on needle point cleaning module and service sink side wall, for being cleaned to service sink conveying cleaning solution to sampling needle needle point;Sampling needle inner wall washing module is connected to sampling needle, for driving cleaning solution back and forth to clean the inner wall of sampling needle;The method comprising the steps of: sampling needle being protruded into service sink, and its needle point is made to be located at the lower section of interface and service sink connectivity part;The needle point that the first cleaning solution rinses sampling needle is passed through into service sink;The first cleaning solution is extracted, and the first cleaning solution is driven back and forth to clean the inner wall of sampling needle;Above-mentioned apparatus structure is simple, easy to operate, without complicated fluid path timing, matches with swab in the prior art, can avoid carrying and pollute to inside and outside sampling needle and needle point carries out comprehensively thoroughly cleaning.

Description

Sampling needle cleaning device and cleaning method
Technical field
The present invention relates to sample analysis technical field, in particular to a kind of sampling needle cleaning device and cleaning method.
Background technique
The sampling needle of sample analyser is needed to clean sampling needle, otherwise be sampled after drawing blood sample in heparin tube Sample can be remained on needle inner wall, outer wall and needle point, to next time sampling and detection cause carry pollute.It is thin compared to blood Born of the same parents, protein, such as C reactive protein (CRP) are more difficult cleaned dry in the residual that sampling needle inner wall, outer wall and needle point are formed Only, this is because protein volume ratio haemocyte is smaller, while surface will form caused by non-specific adsorption with charge. That is, reducing the carrying pollution of protein, the especially carrying pollution of high level sample, is current haemocyte-egg on the market The problem that white matter joint-detection instrument is faced.
Its principle of sampling needle cleaning device used by haemocyte-protein joint-detection analyzer on the market at present It is essentially identical, it is exactly the entrance and exit that dilution is set on a kind of sampling needle flusher (swab), entrance is into swab It is passed through dilution, then negative pressure is introduced in outlet and siphons away dilution, dilution completes pair during swab internal motion The cleaning of sampling needle.
Although above-mentioned sampling needle flusher can play certain effect in terms of reducing carrying pollution, still remain Following Railway Project, first, the inner wall of sampling needle is unable to get and cleans well, because cleaning in sampling needle inside swab The dilution flow velocity of wall must be mutually matched with the dilution flow velocity of cleaning outer wall, if the diluent stream of cleaning sampling needle inner wall Speed is excessive to form leakage in swab bottom, if but flow velocity is too small and can not thoroughly clean up sampling needle inner wall;Its Two, carrying out inner wall washing with swab is typically all that dilution unidirectionally washes away sampling needle inner wall, when analyzing high level sample, Jin Jindan It can not thoroughly be rinsed by small volume, and with the stronger protein of sampling needle inner wall adhesive force to rinsing, this is because liquid Approximate laminar flow is flowed in needle, is more proximate to the region of sampling needle inner wall, and the flow velocity of fluid is also just smaller, and impact force is insufficient, clearly It is poor to wash effect;Third, the needle point of sampling needle is particularly easy to form sample residual, it is difficult to rinse well at needle point with swab merely, When especially sampling process is punctured, also has part debris of rubber stopper and be adhered to sampling needle point, it is difficult to clear up.
Therefore, how to improve sampling needle cleaning device and method, to improve the cleaning effect to sampling needle inner wall and needle point, The residual sample of the above-mentioned position of sampling needle is reduced, and then avoids carrying and pollute, becomes those skilled in the art's weight urgently to be resolved Want technical problem.
Summary of the invention
In view of this, the first purpose of this invention is to provide a kind of sampling needle cleaning device, to improve to sampling needle The cleaning effect of inner wall and needle point, reduces the residual sample of the above-mentioned position of sampling needle, and then avoids carrying and pollute, and of the invention the Two purposes are to provide a kind of sampling needle cleaning method based on above-mentioned sampling needle cleaning device.
To achieve the above object, the invention provides the following technical scheme:
A kind of sampling needle cleaning device, comprising:
Service sink;
Orifice on needle point cleaning module, with service sink side wall, for service sink conveying cleaning solution to adopting Sample needle needle point is cleaned;
Sampling needle inner wall washing module, is connected to sampling needle, for driving cleaning solution to carry out the inner wall of the sampling needle Reciprocal cleaning.
Preferably, the cross section of the service sink is circle, and the interface on the service sink side wall is along the service sink Tangential direction is connected to the service sink.
Preferably, the interface on the service sink side wall is diagonally downward.
Preferably, the needle point cleaning module includes first pressure source and the first container for holding cleaning solution, institute First pressure source is stated to extract cleaning solution from the first container and be sent to the service sink.
Preferably, the first pressure source is syringe pump, and the needle point cleaning module further includes the first control valve, described the Interface on one container, the first pressure source and the service sink side wall is connected to first control valve, and described The first container can be connected to by one control valve with the first pressure source in the first state, and first control valve is It can be by the orifice on the first pressure source and the service sink side wall under two-state.
Preferably, the sampling needle inner wall washing module includes second pressure source, the one end of the sampling needle far from needle point It is connected to the second pressure source, the second pressure source is capable of providing positive pressure and negative pressure to drive cleaning solution to move back and forth.
Preferably, the sampling needle inner wall washing module further includes the second control valve and second container, the sampling needle One end far from needle point is connected to by second control valve with the second pressure source, the second container and second control The second container can be connected to by valve connection processed, second control valve with the second pressure source in the first state, institute State the second control valve in the second condition can be connected in the second pressure source with the sampling needle far from one end of needle point.
It preferably, further include sampling needle outer wall washing module, the sampling needle outer wall washing module includes swab and clear Washing lotion conveying device, the sampling needle from the inner cavity of the swab stretch out, and be provided on the swab be connected to inner cavity into Mouthful, the inlet communication of the cleaning solution conveying device and the swab.
Preferably, the cleaning bottom of pond portion is provided with outlet, and the outlet of the service sink is connected to waste liquid conveying device.
A kind of sampling needle cleaning method, comprising steps of
1) interface and service sink connectivity part for sampling needle being protruded into service sink, and being located at its needle point on service sink side wall Lower section;
2) needle point that the first cleaning solution rinses sampling needle is passed through into service sink;
3) the first cleaning solution is extracted, and it is reciprocal clear with the inner wall progress to sampling needle to drive the first cleaning solution to move back and forth It washes.
Preferably, the first cleaning solution extracted in the step 3) is that the step 2) lodges in service sink after the completion First cleaning solution, the step 3) are specially and to extract in the first cleaning solution for being immersed in the needle point of sampling needle in service sink The first cleaning solution in service sink back and forth cleans the inner wall of sampling needle.
Preferably, it further comprises the steps of:
4) the second cleaning solution is extracted to clean the inner wall of sampling needle to remove remaining first cleaning solution.
Preferably, it further comprises the steps of:
5) rise to sampling needle in swab and be detached from the cleaning solution in service sink, be passed through into swab the second cleaning solution with Clean the outer wall of sampling needle;
6) waste liquid in service sink is emptied.
Preferably, if first cleaning solution is identical as second cleaning solution, institute is directly entered from the step 3) State step 5)
Preferably, first cleaning solution is hemolytic agent, and second cleaning solution is dilution.
In order to reach above-mentioned first purpose, sampling needle cleaning device provided by the invention, including the cleaning of service sink, needle point Module and sampling needle inner wall washing module, wherein service sink for accepting cleaning solution, the upper end be formed with for sampling needle into Opening out, and the interface entered for cleaning solution is formed on its side wall;Interface on needle point cleaning module and service sink side wall Connection, for being cleaned to service sink conveying cleaning solution to sampling needle needle point;Sampling needle inner wall washing module and sampling needle connect Logical, for driving cleaning solution back and forth to clean the inner wall of sampling needle, the cleaning solution for back and forth cleaning sampling needle inner wall can To be to lodge in the cleaning solution in service sink after cleaning needle point, other cleaning solution also can be used;
In order to reach above-mentioned second purpose, the present invention also provides a kind of samplings based on above-mentioned sampling needle cleaning device Needle cleaning method, comprising steps of the interface that 1) sampling needle is protruded into service sink, and is located at its needle point on service sink side wall with The lower section of service sink connectivity part;2) needle point that the first cleaning solution rinses sampling needle is passed through into service sink;3) the first cleaning is extracted Liquid, and the reciprocating movement of the first cleaning solution is driven back and forth to be cleaned with the inner wall to sampling needle;
It can be seen that above-mentioned apparatus structure is simple, and it is easy to operate, it, can be to the needle point of sampling needle without complicated fluid path timing And inner wall is adequately cleaned, and is reduced the sample residual of sampling needle needle point and inner wall, is matched with swab in the prior art It closes, thoroughly cleaning can be carried out comprehensively to sampling needle inside and outside wall and needle point, avoid carrying and pollute.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with It obtains other drawings based on these drawings.
Fig. 1 is the structural schematic diagram of sampling needle cleaning device provided in an embodiment of the present invention;
Fig. 2 is the top view of the service sink of sampling needle cleaning device provided in an embodiment of the present invention;
Fig. 3 is the flow chart of sampling needle cleaning method provided in an embodiment of the present invention.
In figure:
1 is service sink;2 be interface;3 be sampling needle;4 be swab;5 be the second control valve;6 be third control valve;7 be One control valve;8 be the first container;9 be second container;10 be first pressure source;11 be third pressure source;12 be second pressure Source;13 be the 4th control valve;14 be the 5th control valve;15 be waste drains pump.
Specific embodiment
The first purpose of this invention is to provide a kind of sampling needle cleaning device, the structure reality of the sampling needle cleaning device Border can be improved the cleaning effect to sampling needle inner wall and needle point, reduce the residual sample of the above-mentioned position of sampling needle, and then avoid Pollution is carried, a second object of the present invention is to provide a kind of sampling needle cleaning methods based on above-mentioned sampling needle cleaning device.
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Referring to Fig. 1, Fig. 1 is the structural schematic diagram of sampling needle cleaning device provided in an embodiment of the present invention.
The embodiment of the invention provides a kind of sampling needle cleaning devices, including service sink 1, needle point cleaning module and sampling Needle inner wall washing module, wherein service sink 1 is formed with the opening passed in and out for sampling needle 3 for accepting cleaning solution, the upper end, And the interface 2 entered for cleaning solution is formed on its side wall;Needle point cleaning module is connected to the interface 2 on 1 side wall of service sink, is used 3 needle point of sampling needle is cleaned in conveying cleaning solution to service sink 1;Sampling needle inner wall washing module is connected to sampling needle 3, is used The inner wall of sampling needle 3 is back and forth cleaned in driving cleaning solution, the cleaning solution for back and forth cleaning 3 inner wall of sampling needle can be The cleaning solution in service sink 1 is lodged in after cleaning needle point, other cleaning solution also can be used.
Compared with prior art, sampling needle cleaning device provided by the invention, structure is simple, easy to operate, when in use, First the needle point of sampling needle 3 is protruded into service sink 1, and ensures interface 2 and service sink 1 that its needle point is located on 1 side wall of service sink The lower section of connectivity part, is then passed through the needle point that cleaning solution rinses sampling needle 3 into service sink 1, and the cleaning solution used lodges in In service sink 1, for next step cleaning or directly exhaust, then sampling needle inner wall washing module drive cleaning solution is to sampling needle 3 inner walls are back and forth rinsed, i.e. driving cleaning solution moves back and forth inside sampling needle 3, from both direction to being attached to sampling needle 3 The residual sample of inner wall is washed away to improve Scavenging activity, can needle point and inner wall to sampling needle 3 by above-mentioned cleaning device Sufficiently effective cleaning is carried out, with cleaning device for outer walls in the prior art is closed, can make inside and outside sampling needle 3 and needle point is filled Distinguish it is clean, avoid carry pollute.
Referring to Fig. 2, Fig. 2 is the top view of the service sink of sampling needle cleaning device provided in an embodiment of the present invention, at this In inventive embodiments, the cross section of service sink 1 is circle, the interface 2 on 1 side wall of service sink along service sink 1 tangential direction with Service sink 1 is connected to, and by above structure, the cleaning solution for cleaning needle point can be passed through service sink 1 along a tangential direction, along pool wall stream Dynamic formed is vortexed, and increases the contact area of cleaning solution and needle point, and reduces the spilling of cleaning solution, makes cleaning solution with higher flow velocity 3 needle point of sampling needle is rinsed, realizes the thorough cleaning of needle point.
Above-mentioned technical proposal is advanced optimized, it in embodiments of the present invention, should while tangentially accessing service sink 1 Interface 2 on 1 side wall of service sink is also connect with service sink 1 inclined downward, i.e., when being cleaned to needle point, cleaning solution flowing Direction is diagonally downward, washing away downwards to needle point can be formed, by residual sample band to the direction far from needle point, thus further Promote the cleaning effect of needle point.
The effect of needle point cleaning module is that feed liquid way can be continuous supply, right to the offer cleaning solution of service sink 1 Needle point, which is formed, continuously to be washed away, for example can be extracted cleaning solution by water pump and be fed to service sink 1, and multiple confession can also be segmented It gives, to form repeat impact to needle point, for example plunger pump can be used, be used cooperatively non-return valve knot using the reciprocating movement of piston Then structure pushes in service sink 1 from cleaning solution is extracted in soda liquor container, in embodiments of the present invention, needle point cleaning module The first container 8 including first pressure source 10 and for holding cleaning solution, first pressure source 10 are extracted clearly from the first container 8 Washing lotion is simultaneously sent to service sink 1, and specifically, first pressure source 10 is syringe pump, that is, be can provide positive pressure, also be can provide negative pressure, And a certain amount of cleaning solution can be stored, needle point cleaning module further includes the first control valve 7, the first container 8, first pressure source 10 And the interface 2 on 1 side wall of service sink is connected to the first control valve 7, the first control valve 7 in the first state can be by first Container 8 is connected to first pressure source 10, and the first control valve 7 in the second condition can be by first pressure source 10 and 1 side of service sink Interface 2 on wall is connected to, and when in use, the first control valve 7 is first in first state, and syringe pump and the first container 8 connect at this time Logical, syringe pump provides negative pressure, and after extracting the cleaning solution in the first container 8, the first control valve 7 is converted to the second state, will inject Pump be connected to the interface 2 on 1 side wall of service sink, syringe pump offer positive pressure push cleaned 1 side wall of pond of cleaning solution on interface 2 into Enter service sink 1.
The effect of sampling needle inner wall washing module is back and forth to clean 3 inner wall of sampling needle, therefore it needs to push cleaning solution It moves back and forth, for this purpose, in embodiments of the present invention, sampling needle inner wall washing module includes that can provide the second pressure of positive pressure and negative pressure Power source 12, as shown in Figure 1, identical as first pressure source 10, second pressure source 12 is also syringe pump, and sampling needle 3 is far from needle point One end is connected to second pressure source 12, and second pressure source 12 drives cleaning solution to move back and forth by positive pressure and negative pressure.
Since sampling needle cleaning device provided in an embodiment of the present invention is mainly for the cleaning of the stronger protein of adhesive force, Therefore the cleaning solution held in above-mentioned the first container 8 is hemolytic agent, i.e., used during cleaning needle point and inner wall Cleaning solution is hemolytic agent, hemolytic agent compared with the existing technology in dilution, cleaning stronger for the solvability of protein Effect is more preferable, but hemolytic agent can interfere sampling next time, therefore after use hemolytic agent cleaning, to avoid hemolytic agent residual 3 inner wall of sampling needle is stayed in, diluent should be used to clean again to 3 inner wall of sampling needle.
To achieve the above object, sampling needle inner wall washing module further includes the second control valve 5 and second container 9, sampling The one end of needle 3 far from needle point is connected to by the second control valve 5 with second pressure source 12, and second container 9 and the second control valve 5 connect Logical, second container 9 can be connected to by the second control valve 5 with second pressure source 12 in the first state, and the second control valve 5 is second Second pressure source 12 can be connected to sampling needle 3 far from one end of needle point under state, in embodiments of the present invention, second container The cleaning solution held in 9 is dilution;After needle point cleaning module completes the cleaning to needle point, the second control valve 5 is in second State, second pressure source 12 are connected to sampling needle 3, and second pressure source 12 provides the cleaning solution in negative pressure extracting service sink 1, then It provides positive pressure to push back the cleaning solution of extraction, and so on realizes the reciprocal cleaning to 3 inner wall of sampling needle;Then the second control valve 5 are switched to first state, and second pressure source 12 is connected to second container 9, and dilution is extracted in second pressure source 12 from second container 9 Liquid, the second control valve 5 switches to the second state later, and second pressure source 12 is connected to sampling needle 3, and second pressure source 12 is released Dilution carries out secondary cleaning to 3 inner wall of sampling needle into sampling needle 3, to remove remaining hemolytic agent.
After completing the above-mentioned cleaning to needle point and inner wall, the cleaning of sampling needle 3 is not fully complete, it is also necessary to sampling The outer wall of needle 3 is cleaned, in embodiments of the present invention, as shown in Figure 1, sampling needle cleaning device further includes that sampling needle outer wall is clear Mold cleaning block, sampling needle outer wall washing module include swab 4 and cleaning solution conveying device, and sampling needle 3 is stretched from the inner cavity of swab 4 Out, the import being connected to itself inner cavity, the inlet communication of cleaning solution conveying device and swab 4, by adopting and are provided on swab 4 Sample needle 3 or moving up and down for swab 4 clean the outer wall of sampling needle 3.
In the specific embodiment of the invention, the cleaning solution that cleaning solution conveying device is provided to swab 4 is dilution, therefore, As shown in Figure 1, cleaning solution conveying device includes third pressure source 11, and third pressure source 11 by second container 9 and swab 4 into Mouth connection, naturally it is also possible to primary to the progress of 3 outer wall of sampling needle clear using hemolytic agent using other feed liquid ways, such as first It washes, then reuses dilution and secondary cleaning is carried out to 3 outer wall of sampling needle.
Above-mentioned technical proposal is advanced optimized, as shown in Figure 1, third pressure source 11 is also syringe pump, therefore cleaning solution is defeated Sending device further includes third control valve 6, and third pressure source 11 is connected to by third control valve 6 with second container 9 in the first state, The inlet communication of third pressure source 11 and swab 4 drops in the second condition.
In embodiments of the present invention, the first above-mentioned control valve 7, the second control valve 5 and third control valve 6 are two Three-way magnetic valve.
Cleaning solution on swab 4 after use can be such that it directly flows into service sink 1 along sampling needle 3, can also carry out to it Recycling, guides its discharge, as shown in Figure 1, being additionally provided with outlet on swab 4, the outlet of swab 4 is connected to waste liquid conveying device, In this way, the cleaning with swab 4 to 3 outer wall of sampling needle, used cleaning solution siphons away discharge by waste liquid conveying device simultaneously.
Further, 1 bottom of service sink is provided with outlet, and the outlet of service sink 1 is connected to waste liquid conveying device.
As shown in Figure 1, in embodiments of the present invention, waste liquid conveying device includes waste drains pump 15 and two branches, one Branch is gone out by the 4th control valve 13 and 4 outlet of swab, another article of branch by the 5th control valve 14 and 1 bottom of service sink Mouth connection can open the 4th control valve 13 or the 5th control valve 14 according to wash course and arrange waste liquid in time in use Out.
Sampling needle cleaning device provided by the invention needs sampling needle 3 to be moved to different positions in different wash phases It sets, for example, sampling needle 3 needs to explore downward in service sink 1 to clean needle point, is needed to rise in swab 4 clearly after having cleaned inner wall Wash outer wall, therefore in the embodiment of the present invention, sampling needle cleaning device may also include 3 mobile device of sampling needle, with to sampling needle 3 into Row X can also directly make to, the movement of Y-direction and Z-direction if blood cell analyzer has the mobile function of sampling needle 3 certainly The movement of sampling needle 3 is realized with the function.
The embodiment of the invention also provides a kind of sampling needle cleaning methods based on above-mentioned sampling needle cleaning device, please refer to Fig. 3, Fig. 3 are the flow chart of sampling needle cleaning method provided in an embodiment of the present invention, and the method comprising the steps of:
S1: sampling needle 3 is protruded into service sink 1, and the interface 2 for being located at its needle point on 1 side wall of service sink and service sink 1 The lower section of connectivity part;
In this course, the depth for protruding into service sink 1 of sampling needle 3 is preferably controlled, guarantees needle point and 1 side wall of service sink On 2 axis of interface be connected to a bit, to guarantee that cleaning solution is directly formed the needle point of sampling needle 3 when flowing into service sink 1 Impact.
S2: the needle point that the first cleaning solution rinses sampling needle 3 is passed through into service sink 1;
When being passed through the first cleaning solution, the first cleaning solution should be made to have certain flow velocity, with the needle point shape to sampling needle 3 At impact, cleaning effect is improved, in embodiments of the present invention, the first cleaning solution is hemolytic agent, is applied to different samplings certainly It, can also be using other cleaning solutions, it is not limited here when equipment.
S3: extracting the first cleaning solution, and it is reciprocal clear with the inner wall progress to sampling needle 3 to drive the first cleaning solution to move back and forth It washes;
First cleaning solution used in above-mentioned steps can clean to accumulate in first in service sink 1 after cleaning needle point Liquid can also be extracted from other places, with cleaning needle point it is identical, clean inner wall the first cleaning solution must also have certain flow velocity with Realize the impact to the attachment on inner wall.
Due to needle point small volume, remaining sample is less thereon, can also continue to the first cleaning solution after needle point cleaning It uses, therefore, in the specific embodiment of the invention, the first cleaning solution extracted in step S3 lodges in clear after the completion of being step S2 The first cleaning solution in wash pool 1, step S3 be specially be immersed in the needle point of sampling needle 3 in service sink 1 the first cleaning solution in, And it extracts the first cleaning solution in service sink 1 and the inner wall of sampling needle 3 is back and forth cleaned.
Certainly, in other examples, can also be carried out using inner wall of the completely new not used cleaning solution to sampling needle 3 Cleaning.
Further, above-mentioned sampling needle cleaning method further comprises the steps of:
S4: it extracts the second cleaning solution and the inner wall of sampling needle 3 is cleaned to remove remaining first cleaning solution;
In embodiments of the present invention, the second cleaning solution is dilution, to remove remaining first cleaning solution, is avoided first clear Washing lotion causes adverse effect to sampling next time, when being cleaned using the second cleaning solution to 3 inner wall of sampling needle, it is necessary to first make to adopt Sample needle 3 climbs away the first cleaning solution in service sink 1, or first empties the first cleaning solution in service sink 1.
Preferably to remove isolating protein, in embodiments of the present invention, it is used cooperatively using two kinds of cleaning solutions, wherein first Cleaning solution is hemolytic agent, the dilution of the second cleaning solution, certainly in practical application, can also be only with a kind of cleaning solution to adopting Sample needle is cleaned, i.e., the first cleaning solution is identical as the second cleaning solution, and in this case, above-mentioned sampling needle cleaning method is skipped Step S4 is directly entered step S5. by step S3
After the completion of aforementioned four step, the inner wall and needle point of sampling needle 3 have been completed to clean, next will also be to sampling The outer wall of needle 3 is cleaned, as shown in figure 3, sampling needle cleaning method further comprises the steps of:
S5: it is clear to be passed through second into swab 4 for the cleaning solution for rising to sampling needle 3 in swab 4 and being detached from service sink 1 Washing lotion is to clean the outer wall of sampling needle 3;
In embodiments of the present invention, directlying adopt the second cleaning solution, i.e. dilution cleans the outer wall of sampling needle 3, In other embodiments, the second cleaning solution, which is reused, after can also first cleaning using the first cleaning solution carries out secondary cleaning.
S6: the waste liquid in emptying service sink 1.
Above-mentioned technical proposal is advanced optimized, in embodiments of the present invention, is being passed through second into swab 4 clearly in step S5 Washing lotion drains the second cleaning solution that 3 outer wall of sampling needle has been rinsed in swab 4 while cleaning 3 outer wall of sampling needle.
Above-described embodiment is cleaned according to sampling needle needle point → sampling needle inner wall → sampling needle outer wall sequence, but this is only It is only a kind of optimum implementation provided by the invention, is actually not limited thereto, said sequence can be upset, according to sampling needle Inner wall → sampling needle needle point → sampling needle outer wall sequence is cleaned, or is carried out in any order, it is not limited here.
As described above, the embodiment of the invention provides a kind of sampling needle cleaning device and being based on the sampling needle cleaning device Sampling needle cleaning method, the apparatus structure is simple, convenient for operation, above-mentioned apparatus combination method can needle point to sampling needle 3 and Inner wall carries out sufficiently effective cleaning, with cleaning device for outer walls is closed, can make inside and outside sampling needle 3 and needle point is sufficiently cleaned, It avoids carrying and pollute.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other The difference of embodiment, the same or similar parts in each embodiment may refer to each other.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one The widest scope of cause.

Claims (15)

1. a kind of sampling needle cleaning device characterized by comprising
Service sink;
Orifice on needle point cleaning module, with service sink side wall, for conveying cleaning solution to sampling needle to the service sink Needle point is cleaned;
Sampling needle inner wall washing module, is connected to sampling needle, reciprocal for driving cleaning solution to carry out the inner wall of the sampling needle Cleaning.
2. sampling needle cleaning device according to claim 1, which is characterized in that the cross section of the service sink is circle, Interface on the service sink side wall is connected to along the tangential direction of the service sink with the service sink.
3. sampling needle cleaning device according to claim 2, which is characterized in that the interface inclination on the service sink side wall Downwards.
4. sampling needle cleaning device according to claim 1 to 3, which is characterized in that the needle point cleaning module The first container including first pressure source and for holding cleaning solution, the first pressure source are extracted from the first container Cleaning solution is simultaneously sent to the service sink.
5. sampling needle cleaning device according to claim 4, which is characterized in that the first pressure source is syringe pump, institute Stating needle point cleaning module further includes the first control valve, the first container, the first pressure source and the service sink side wall On interface be connected to first control valve, first control valve in the first state can by the first container with The first pressure source connection, first control valve in the second condition can be by the first pressure source and the service sink Orifice on side wall.
6. sampling needle cleaning device described in -3 and 5 any one according to claim 1, which is characterized in that in the sampling needle Wall cleaning module includes second pressure source, and the one end of the sampling needle far from needle point is connected to the second pressure source, and described Two pressure source is capable of providing positive pressure and negative pressure to drive cleaning solution to move back and forth.
7. sampling needle cleaning device according to claim 6, which is characterized in that the sampling needle inner wall washing module is also wrapped The second control valve and second container are included, the sampling needle passes through second control valve and described second far from one end of needle point Pressure-source communication, the second container are connected to second control valve, and second control valve can incite somebody to action in the first state The second container is connected to the second pressure source, and second control valve in the second condition can be by the second pressure Source is connected to the sampling needle far from one end of needle point.
8. sampling needle cleaning device described in -3,5 and 7 any one according to claim 1, which is characterized in that further include sampling Needle outer wall washing module, the sampling needle outer wall washing module include swab and cleaning solution conveying device, the sampling needle from The inner cavity of the swab is stretched out, and the import being connected to inner cavity is provided on the swab, the cleaning solution conveying device and institute State the inlet communication of swab.
9. sampling needle cleaning device according to claim 8, which is characterized in that the cleaning bottom of pond portion is provided with outlet, The outlet of the service sink is connected to waste liquid conveying device.
10. a kind of sampling needle cleaning method, which is characterized in that comprising steps of
1) under the interface and service sink connectivity part that protrude into service sink sampling needle, and be located at its needle point on service sink side wall Side;
2) needle point that the first cleaning solution rinses sampling needle is passed through into service sink;
3) the first cleaning solution is extracted, and the reciprocating movement of the first cleaning solution is driven back and forth to be cleaned with the inner wall to sampling needle.
11. sampling needle cleaning method according to claim 10, which is characterized in that first extracted in the step 3) is clear Washing lotion is the first cleaning solution that the step 2) is lodged in after the completion in service sink, and the step 3) is specially the needle for making sampling needle Point is immersed in the first cleaning solution in service sink, and extract the first cleaning solution in service sink the inner wall of sampling needle is carried out it is past Multiple cleaning.
12. sampling needle cleaning method described in 0 or 11 according to claim 1, which is characterized in that further comprise the steps of:
4) the second cleaning solution is extracted to clean the inner wall of sampling needle to remove remaining first cleaning solution.
13. sampling needle cleaning method according to claim 12, which is characterized in that further comprise the steps of:
5) it rises to sampling needle in swab and is detached from the cleaning solution in service sink, be passed through the second cleaning solution into swab to clean The outer wall of sampling needle;
6) waste liquid in service sink is emptied.
14. sampling needle cleaning method according to claim 13, which is characterized in that if first cleaning solution and described the Two cleaning solutions are identical, then are directly entered the step 5) from the step 3).
15. sampling needle cleaning method according to claim 12, which is characterized in that first cleaning solution is hemolytic agent, Second cleaning solution is dilution.
CN201810411541.1A 2018-05-02 2018-05-02 Sampling needle cleaning device and cleaning method Active CN110434128B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810411541.1A CN110434128B (en) 2018-05-02 2018-05-02 Sampling needle cleaning device and cleaning method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810411541.1A CN110434128B (en) 2018-05-02 2018-05-02 Sampling needle cleaning device and cleaning method

Publications (2)

Publication Number Publication Date
CN110434128A true CN110434128A (en) 2019-11-12
CN110434128B CN110434128B (en) 2021-10-29

Family

ID=68426969

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810411541.1A Active CN110434128B (en) 2018-05-02 2018-05-02 Sampling needle cleaning device and cleaning method

Country Status (1)

Country Link
CN (1) CN110434128B (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111983249A (en) * 2020-08-28 2020-11-24 沈阳瑞好生物科技有限公司 Chemiluminescence immunodetection analyzer for in-situ luminescence determination and detection method
CN112858660A (en) * 2019-11-28 2021-05-28 深圳市帝迈生物技术有限公司 Magnetic separation cleaning system and imbibition needle subassembly, immunoassay appearance thereof
CN112858659A (en) * 2019-11-28 2021-05-28 深圳市帝迈生物技术有限公司 Sampling needle cleaning system, sample analyzer and immune luminescence analyzer
CN113311163A (en) * 2020-02-26 2021-08-27 深圳迈瑞生物医疗电子股份有限公司 Cleaning method of detection pool
CN114082455A (en) * 2021-10-21 2022-02-25 华南理工大学 Recyclable hollow cantilever probe front end loading and cleaning method
CN114308849A (en) * 2020-09-29 2022-04-12 深圳市帝迈生物技术有限公司 Method for avoiding liquid level error detection and sample analyzer
CN114643241A (en) * 2020-12-18 2022-06-21 深圳市帝迈生物技术有限公司 Liquid supply system and liquid supply method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4817443A (en) * 1986-11-14 1989-04-04 A.B.X. Device for cleaning a liquid sample taking needle
CN101869894A (en) * 2009-04-24 2010-10-27 深圳迈瑞生物医疗电子股份有限公司 Cleaning device, cleaning system, cleaning method and particle analyzer
CN104107815A (en) * 2013-04-16 2014-10-22 深圳迈瑞生物医疗电子股份有限公司 Cleaning device of sampling needle, cleaning method of sampling needle and sample analyzing device
CN105562389A (en) * 2014-10-16 2016-05-11 北京普利生仪器有限公司 Sampling needle cleaning system and sampling needle cleaning method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4817443A (en) * 1986-11-14 1989-04-04 A.B.X. Device for cleaning a liquid sample taking needle
CN101869894A (en) * 2009-04-24 2010-10-27 深圳迈瑞生物医疗电子股份有限公司 Cleaning device, cleaning system, cleaning method and particle analyzer
CN104107815A (en) * 2013-04-16 2014-10-22 深圳迈瑞生物医疗电子股份有限公司 Cleaning device of sampling needle, cleaning method of sampling needle and sample analyzing device
CN105562389A (en) * 2014-10-16 2016-05-11 北京普利生仪器有限公司 Sampling needle cleaning system and sampling needle cleaning method

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112858660A (en) * 2019-11-28 2021-05-28 深圳市帝迈生物技术有限公司 Magnetic separation cleaning system and imbibition needle subassembly, immunoassay appearance thereof
CN112858659A (en) * 2019-11-28 2021-05-28 深圳市帝迈生物技术有限公司 Sampling needle cleaning system, sample analyzer and immune luminescence analyzer
CN113311163A (en) * 2020-02-26 2021-08-27 深圳迈瑞生物医疗电子股份有限公司 Cleaning method of detection pool
CN113311163B (en) * 2020-02-26 2024-04-12 深圳迈瑞生物医疗电子股份有限公司 Cleaning method of detection pool
CN111983249A (en) * 2020-08-28 2020-11-24 沈阳瑞好生物科技有限公司 Chemiluminescence immunodetection analyzer for in-situ luminescence determination and detection method
CN114308849A (en) * 2020-09-29 2022-04-12 深圳市帝迈生物技术有限公司 Method for avoiding liquid level error detection and sample analyzer
CN114308849B (en) * 2020-09-29 2023-04-18 深圳市帝迈生物技术有限公司 Method for avoiding liquid level error detection and sample analyzer
CN114643241A (en) * 2020-12-18 2022-06-21 深圳市帝迈生物技术有限公司 Liquid supply system and liquid supply method
CN114643241B (en) * 2020-12-18 2023-12-01 深圳市帝迈生物技术有限公司 Liquid supply system and liquid supply method
CN114082455A (en) * 2021-10-21 2022-02-25 华南理工大学 Recyclable hollow cantilever probe front end loading and cleaning method

Also Published As

Publication number Publication date
CN110434128B (en) 2021-10-29

Similar Documents

Publication Publication Date Title
CN110434128A (en) Sampling needle cleaning device and cleaning method
CN208636331U (en) Sampling needle cleaning device
CN105344679A (en) Automatic double liquid injecting and washing device for test tubes
CN101869894B (en) Clean device, purging system, cleaning method and particle analyzer
CN104107815A (en) Cleaning device of sampling needle, cleaning method of sampling needle and sample analyzing device
CN105327917A (en) Double washing device with water level monitoring function for test tube
CN110320379A (en) A kind of sample analyser and its cleaning method
CN207119614U (en) A kind of automatic liquid relief and purging system
CN205587405U (en) Dual device of washhing of test tube with water level monitoring
CN108480349B (en) A kind of flask for medicinal preparations cleaning method
JPH04105065A (en) Cup washing device
CN203725457U (en) Pneumatic bottle washing machine
CN205949427U (en) Nuclear -magnetic pipe cleaning device
CN205587391U (en) Automatically, annotate dual liquid washs device to test tube
CN205587408U (en) Test tube device of scrubbing and spin -dry
CN212633745U (en) Full-automatic biochemical analyzer with high-efficient belt cleaning device
CN205217543U (en) Automatically, annotate liquid washs device to test tube
CN207971181U (en) A kind of cleaning device of pharmaceutical test sample introduction bottle
CN208527448U (en) A kind of cleaning swab
CN205587387U (en) Automatic dual belt cleaning device of liquid that annotates of test tube
CN205324307U (en) Test tube brushing device
CN208341285U (en) A kind of nuclear-magnetism can washing apparatus
CN205587388U (en) Automatically, annotate dual liquid washs device to test tube
CN105903734B (en) A kind of ELISA Plate cleaning protection lid and board-washing machine
CN205587385U (en) Automatic dual washing of liquid and device that spin -dries annotated of test tube

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant