CN103230897B - A kind of cleaning device and cleaning method - Google Patents
A kind of cleaning device and cleaning method Download PDFInfo
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- CN103230897B CN103230897B CN201310142205.9A CN201310142205A CN103230897B CN 103230897 B CN103230897 B CN 103230897B CN 201310142205 A CN201310142205 A CN 201310142205A CN 103230897 B CN103230897 B CN 103230897B
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- rinse bath
- waste liquid
- reaction cup
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Abstract
A kind of cleaning device, comprise the reaction cup purging system for cleaning reaction cup and the rinse bath system response cup purging system for cleaning needle group comprises cleaning needle and waste liquid pin, waste liquid pin is connected with multi-headed peristaltic pump by tube connector, at least one cleaning needle is connected with a plunger displacement pump by tube connector, between cleaning needle and described plunger displacement pump, be provided with solenoid electric valve.Beneficial effect is: the present invention adds solenoid electric valve in reaction cup purging system, and two cleaning needles share a control valve, like this, can realize the independent control operation of every root cleaning needle; The use of ultrasonic cleaner ensure that the completeness that cleaning needle cleans; Cleaning needle cleans magnetic bead surfaces bond, and waste liquid pin disposes waste liquid in time, and both common uses are protected and magnetic bead surfaces bond and discards are thoroughly cleaned; It is simple that the present invention has structure, easy-to-use, without cross-infection, advantage with low cost.
Description
Technical field
The present invention relates to fields of immunochemistry analysis, especially relate to a kind of Full-automatic tube-type chemical analyzer cleaning device and use the cleaning method of this cleaning device.
Background technology
Immunodiagnosis is the principle of applied immunology, techniques and methods diagnoses various disease and measure immune state.Medically, it is the cause of disease and the diseased region of determining disease, or determines the whether normal important method of matrix immune state.The radioimmunoassay technology that tradition uses because its manual operations is complicated, the reaction time long, environmental pollution by force and progressively replace by emerging chemiluminescence immunoassay technology.Chemiluminescence immunoassay technology due to the reaction time short, simple to operate, thus significantly improve the operating efficiency of immunodiagnosis.
Application number is 200510095342.7, application title discloses a kind of cleaning device in the application for a patent for invention of " a kind of automatic cleaning design for the pool full automatic biochemical apparatus that flows ", manner of execution stretches in service sink by reactant sample introduction needle when being cleaning, water in service sink realizes cleaning function according to the sequential flowing of " service sink-reactant sample introduction needle-connecting pipe-flow colorimetric pond-peristaltic pump ", this device is by increasing service sink, by the reactant sample introduction needle after having detected, connecting pipe, flow colorimetric pond, peristaltic pump cleans successively, to make testing result more reliable.But because this device just adopts the method for working fluid cleaning to clean sample introduction needle, the clean-up performance of sample introduction needle cannot ensure, and does not consider the problem that sample introduction needle is cleaned separately in the design.
Application number is 20071002107.4, application title discloses a kind of immune detection system in the application for a patent for invention of " automatic channel resolution chemistry multi-component immunological detection system and analytical method ", this system is by incubation system, fluid delivery system, signal resolution acquisition system and computer are formed, wherein fluid delivery system is by multi-channel peristaltic pump, tube connector and 1-6 multiposition valve composition, tube connector is connected respectively to three valve position entrances of multiposition valve through multi-channel peristaltic pump, entrance is by tube connector transmission dcq buffer liquid, magnetic bead is discharged from sense channel, complete full testing process, and enter into next cycle analysis.This kind of whole analytic process of system all completes in current system, and manual operations is few, but the cleaning only carrying out associated components simply by peristaltic pump still cannot be cleaned thoroughly, and also there is the possibility of cross-infection.
Summary of the invention
The object of the present invention is to provide a kind of cleaning method being used in cleaning device on Full-automatic tube-type chemical analyzer and correspondence, this cleaning device includes the reaction cup purging system cleaned reaction cup and the rinse bath system of cleaning cleaning needle group, the technical scheme adopted is: a kind of cleaning device, comprise the reaction cup purging system for cleaning reaction cup and the rinse bath system for cleaning needle group, it is characterized in that: described reaction cup purging system comprises cleaning needle and waste liquid pin, described waste liquid pin is connected with multi-headed peristaltic pump by tube connector, described at least one cleaning needle is connected with a plunger displacement pump by tube connector, between described cleaning needle and described plunger displacement pump, solenoid electric valve is installed.
Technical characteristic of the present invention also has: two cleaning needles are connected with a solenoid electric valve respectively by tube connector, and described solenoid electric valve is also connected with described plunger displacement pump by a tube connector.
Technical characteristic of the present invention also has: described cleaning needle totally 6.
Technical characteristic of the present invention also has: described rinse bath system comprises rinse bath for placing pin group and ultrasonic vibrator, described ultrasonic vibrator is fixed in ultrasonic wave vibratory chamber, and the sidewall of described ultrasonic wave vibratory chamber is arranged in the kerve of described rinse bath.
Technical characteristic of the present invention also has: described rinse bath also comprises spray system, and described spray system comprises gas blow pipe and liquid pump.
Technical scheme of the present invention also has: a kind of cleaning method realized by cleaning device, this cleaning device comprises the reaction cup purging system for cleaning reaction cup and the rinse bath system for cleaning needle group, described reaction cup purging system comprises cleaning needle and waste liquid pin, described waste liquid pin is connected with multi-headed peristaltic pump by tube connector, at least one cleaning needle is connected with a plunger displacement pump by tube connector, between described cleaning needle and described plunger displacement pump, solenoid electric valve is installed, two cleaning needles are connected with a solenoid electric valve respectively by tube connector, described solenoid electric valve is also connected with described plunger displacement pump by a tube connector, it is characterized in that: said method comprising the steps of:
1) rinse bath advances, and reaction cup is sent in rinse bath by conveyor module;
2) crane drives pin group to decline, and when dropping to certain altitude, cleaning needle injects cleaning fluid in reaction cup, and the waste liquid in reaction cup siphons away by waste liquid pin;
3) the gas blow pipe hydrojet of rinse bath system, the outer wall of cleaning needle group;
4) when the sensor of rinse bath system detects that in rinse bath, liquid level reaches commitment positions, ultrasonic vibrator is opened, and carries out Ultrasonic Cleaning to pin group, and while ultrasonic vibrator unlatching, gas blow pipe stops hydrojet;
5) after the Ultrasonic Cleaning time reaches, extract in rinse bath while waste liquid, gas blow pipe hydrojet cleaning needle group outer wall by liquid pump, after pin group outer wall washing is clean, pin group rises and rinse bath retreats.
Beneficial effect of the present invention is: 1) the present invention adds solenoid electric valve in reaction cup purging system, and two cleaning needles share a control valve, like this, can realize the independent control operation of every root cleaning needle;
2) use of ultrasonic cleaner ensure that the completeness that cleaning needle cleans;
3) cleaning needle cleans magnetic bead surfaces bond, and waste liquid pin disposes waste liquid in time, and both common uses are protected and magnetic bead surfaces bond and discards are thoroughly cleaned.
4) the present invention has structure simply, easy-to-use, without cross-infection, advantage with low cost.
Accompanying drawing explanation
Accompanying drawing 1 is perspective view of the present invention, and accompanying drawing 2 is reaction cup purging system schematic diagrames of the present invention, and accompanying drawing 3 is rinse bath system architecture schematic diagrames, accompanying drawing 4 is cleaning needle and waste liquid needle construction schematic diagram, and wherein 1 is tube connector, and 2 is multi-headed peristaltic pump, 3 is cleaning needles, and 4 is syringes, and 5 is waste liquid pins, 6 is pipe joints, 7 is solenoid electric valves, and 8 is plunger displacement pumps, and 9 is rinse baths, 10 is gas blow pipes, and 11 is ultrasonic vibrators.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is specifically described.The invention discloses a kind of cleaning device, comprise the reaction cup purging system for cleaning reaction cup and the rinse bath system for cleaning needle group.Wherein, reaction cup purging system comprises cleaning needle 3 and waste liquid pin 5, waste liquid pin 5 is connected with multi-headed peristaltic pump 2 by tube connector 1, and at least one cleaning needle 3 is connected with a plunger displacement pump 8 by tube connector 1, is provided with solenoid electric valve 7 between cleaning needle 3 and plunger displacement pump 8.Employ two cleaning needles in the present embodiment to be connected with a solenoid electric valve 7 respectively by tube connector, solenoid electric valve 7 is also connected with plunger displacement pump 8 by a tube connector.Like this, 6 cleaning needles in the present embodiment employ 3 plunger displacement pumps 8 altogether, and every root cleaning needle can be used alone or jointly use with the cleaning needle installed on same plunger displacement pump, therefore present embodiments provides the selection mode that multiple cleaning needle uses.
Rinse bath system comprises rinse bath 9 for placing pin group and ultrasonic vibrator, and ultrasonic vibrator 11 is fixed in ultrasonic wave vibratory chamber, and the sidewall of ultrasonic wave vibratory chamber is arranged in the kerve of rinse bath 9.Rinse bath 9 also comprises spray system, and spray system comprises gas blow pipe 10 and liquid pump.
The cleaning method that cleaning device realizes, the method comprises the following steps:
1) rinse bath 9 advances, and reaction cup is sent in rinse bath 9 by conveyor module;
2) crane drives pin group to decline, and when dropping to certain altitude, cleaning needle injects cleaning fluid in reaction cup, and the waste liquid in reaction cup siphons away by waste liquid pin 5;
3) the gas blow pipe hydrojet of rinse bath spray system, the outer wall of cleaning needle group;
4) when the sensor of rinse bath spray system detects that in rinse bath, liquid level reaches commitment positions, ultrasonic vibrator is opened, and carries out Ultrasonic Cleaning to pin group, and while ultrasonic vibrator unlatching, gas blow pipe stops hydrojet;
5) after the Ultrasonic Cleaning time reaches, extract in rinse bath while waste liquid, gas blow pipe hydrojet cleaning needle group outer wall by liquid pump, after cleaning needle outer wall washing is clean, cleaning needle rises and rinse bath retreats.
Certainly, above-mentioned explanation is not limitation of the present invention, and the present invention is also not limited only to above-mentioned citing, and the change that those skilled in the art make in essential scope of the present invention, remodeling, interpolation or replacement, also belong to protection scope of the present invention.
Claims (1)
1. the cleaning method realized by cleaning device, this cleaning device comprises the reaction cup purging system for cleaning reaction cup and the rinse bath system for cleaning needle group, described reaction cup purging system comprises cleaning needle and waste liquid pin, described waste liquid pin is connected with multi-headed peristaltic pump by tube connector, at least one cleaning needle is connected with a plunger displacement pump by tube connector, between described cleaning needle and described plunger displacement pump, solenoid electric valve is installed, two cleaning needles are connected with a solenoid electric valve respectively by tube connector, described solenoid electric valve is also connected with described plunger displacement pump by a tube connector, it is characterized in that: said method comprising the steps of:
1) rinse bath advances, and reaction cup is sent in rinse bath by conveyor module;
2) crane drives pin group to decline, and when dropping to certain altitude, cleaning needle injects cleaning fluid in reaction cup, and the waste liquid in reaction cup siphons away by waste liquid pin;
3) the gas blow pipe hydrojet of rinse bath spray system, the outer wall of cleaning needle group;
4) when the sensor of rinse bath spray system detects that in rinse bath, liquid level reaches commitment positions, ultrasonic vibrator is opened, and carries out Ultrasonic Cleaning to pin group, and while ultrasonic vibrator unlatching, gas blow pipe stops hydrojet;
5) after the Ultrasonic Cleaning time reaches, extract in rinse bath while waste liquid, gas blow pipe hydrojet cleaning needle group outer wall by liquid pump, after pin group outer wall washing is clean, pin group rises and rinse bath retreats.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310142205.9A CN103230897B (en) | 2013-04-23 | 2013-04-23 | A kind of cleaning device and cleaning method |
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| CN201310142205.9A CN103230897B (en) | 2013-04-23 | 2013-04-23 | A kind of cleaning device and cleaning method |
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| CN103230897A CN103230897A (en) | 2013-08-07 |
| CN103230897B true CN103230897B (en) | 2016-01-20 |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103599898B (en) * | 2013-10-29 | 2015-11-25 | 北京利德曼生化股份有限公司 | Full-automatic chemiluminescence immunoassay analysis meter magnetic bead cleaning device |
| CN105945018B (en) * | 2016-06-23 | 2018-11-20 | 广州埃克森生物科技有限公司 | A kind of biochemical instruments auto-cleaning method and device |
| CN106770913A (en) * | 2016-12-09 | 2017-05-31 | 中储粮成都粮食储藏科学研究所 | A kind of fatty acid value automatic tester |
| CN109520806B (en) * | 2017-09-20 | 2023-09-12 | 深圳迈瑞生物医疗电子股份有限公司 | Sample analyzer and control method thereof |
| CN110548725A (en) * | 2019-10-21 | 2019-12-10 | 上海加奇生物科技苏州有限公司 | Ultrasonic cleaning device system for implant raw material and method for cleaning implant raw material |
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| CN202021171U (en) * | 2011-04-11 | 2011-11-02 | 深圳市康立高科技有限公司 | Automatic cleaning system used for flowing type semi-automatic biochemical analyzer |
| CN102527658A (en) * | 2012-01-17 | 2012-07-04 | 深圳湃尔生物科技有限公司 | Pressure balance system of automatic ELISA (Enzyme-Linked Immunosorbent Assay) plate washer and automatic ELISA plate washer |
| CN203265144U (en) * | 2013-04-23 | 2013-11-06 | 上海裕隆生物科技有限公司 | Washing device |
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| JPH0242362A (en) * | 1988-08-03 | 1990-02-13 | Hitachi Ltd | Cleaning device for automatic analyzing device |
| JPH06313767A (en) * | 1993-04-28 | 1994-11-08 | Medeika Tec Kk | Inspection apparatus for blood and the like using magnetic bead |
| JP2010216876A (en) * | 2009-03-13 | 2010-09-30 | Beckman Coulter Inc | Analyzer and dispensing probe washing method |
| CN102236023B (en) * | 2011-03-30 | 2013-01-09 | 深圳市麦迪聪医疗电子有限公司 | Flowing type multi-channel biochemical analyzer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1535765A (en) * | 2003-04-08 | 2004-10-13 | ������������ʽ���� | Probe cleaning device |
| CN202021171U (en) * | 2011-04-11 | 2011-11-02 | 深圳市康立高科技有限公司 | Automatic cleaning system used for flowing type semi-automatic biochemical analyzer |
| CN102527658A (en) * | 2012-01-17 | 2012-07-04 | 深圳湃尔生物科技有限公司 | Pressure balance system of automatic ELISA (Enzyme-Linked Immunosorbent Assay) plate washer and automatic ELISA plate washer |
| CN203265144U (en) * | 2013-04-23 | 2013-11-06 | 上海裕隆生物科技有限公司 | Washing device |
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Application publication date: 20130807 Assignee: Shanghai Lingang Financial Leasing Co.,Ltd. Assignor: Shanghai Yulong Biotech Co.,Ltd. Contract record no.: X2022980015555 Denomination of invention: A cleaning device and cleaning method Granted publication date: 20160120 License type: Exclusive License Record date: 20220919 |
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Denomination of invention: A cleaning device and cleaning method Effective date of registration: 20220920 Granted publication date: 20160120 Pledgee: Shanghai Lingang Financial Leasing Co.,Ltd. Pledgor: Shanghai Yulong Biotech Co.,Ltd. Registration number: Y2022980015779 |
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