CN201965136U - Flow path system for automation biochemical reaction flow - Google Patents

Flow path system for automation biochemical reaction flow Download PDF

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Publication number
CN201965136U
CN201965136U CN2011200376007U CN201120037600U CN201965136U CN 201965136 U CN201965136 U CN 201965136U CN 2011200376007 U CN2011200376007 U CN 2011200376007U CN 201120037600 U CN201120037600 U CN 201120037600U CN 201965136 U CN201965136 U CN 201965136U
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CN
China
Prior art keywords
sample
waste liquid
washing lotion
valve
pin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN2011200376007U
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Chinese (zh)
Inventor
唐勇
杨卫平
张颖
刘春艳
张雷
徐辉
宋小波
吴永杰
王宪华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sichuan Maker Biological Science And Technology Co Ltd
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Sichuan Maker Biological Science And Technology Co Ltd
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Priority to CN2011200376007U priority Critical patent/CN201965136U/en
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Abstract

The utility model discloses a flow path system for automation biochemical reaction flow, which comprises a washing liquor barrel (1), an automatic sample feeding and sample needle washing system (2), a waste liquor barrel (3) and a reaction pipe washing system (4); two outlets of the washing liquor barrel are respectively connected with the automatic sample feeding and sample needle washing system and the reaction pipe washing system; and two inlets of the waste liquor barrel are respectively connected with the automatic sample feeding and sample needle washing system and the reaction pipe washing system. The flow path system can avoid the uncertainty of manual operation, improve detection efficiency and experiment flux; and in the utility model, an automation mechanism facilitates system integration, and more equipment with automation functions can be manufactured on the basis of the utility model.

Description

A kind of flow path system that is used for automatic biological chemical reaction flow process
Technical field
The utility model relates to a kind of biochemical detecting instrument, particularly a kind of flow path system that is used for automatic biological chemical reaction flow process.
Background technology
Biochemical reaction often need be handled liquid, this in the past reaction all be use by the experimenter experiment equipment of necessity such as pipettor in the laboratory manual finishing, manual operations not only repeatability does not guarantee, and the complicated flow process of biochemical reaction has also seriously limited the flux of experiment.Along with the raising to experiment flux and accuracy requirement, the equipment of finishing the biochemical reaction flow process of robotization has progressively replaced traditional manual operations, and the problem that thereupon produces is exactly to solve fluid operated robotization.
The utility model content
The purpose of this utility model is to provide a kind of flow path system that is used for automatic biological chemical reaction flow process, and it can cooperate automatic mechanism to finish the every fluid operated of flow path.
The purpose of this utility model is achieved through the following technical solutions: a kind of flow path system that is used for automatic biological chemical reaction flow process comprises washing lotion bucket, automatic application of sample and sample pin purging system, waste liquid barrel and reaction tube purging system; Respectively with automatically application of sample and sample pin purging system, reaction tube purging system are connected in two outlets of described washing lotion bucket; Respectively with automatically application of sample and sample pin purging system, reaction tube purging system are connected in two imports of described waste liquid barrel.
Described automatic application of sample and sample pin purging system comprise and express pump, syringe pump, T-valve, sample adding device and pin cleaning device automatically; Described automatic sample adding device comprises the sample pin, and controls the motion that the sample pin moves up and down and rotatablely moves; First joint of described T-valve is connected with syringe pump, second joint with express delivery side of pump and be connected, the 3rd joint is connected with the sample pin of sample adding device automatically; The described input end that expresses pump is connected with the washing lotion bucket; Described pin cleaning device is connected with waste liquid barrel.
Described reaction tube purging system comprises washing lotion peristaltic pump, washing lotion on-off valve, automatic flushing device, waste liquid on-off valve, the waste liquid peristaltic pump that connects successively; The top board that described automatic flushing device comprises the column of base, relatively base vertical movement, be connected with base by column, be fixed on the vertical table on the base and be connected horizontal table on the vertical table, lower surface at horizontal table is equipped with the reaction tube support that moves relative to horizontal table, horizontal table is provided with liquid injection hole and imbibing hole, priming device is installed above liquid injection hole, evenly mixing device is installed under priming device, and top board is provided with the liquid sucking device that passes imbibing hole; The priming device of described automatic flushing device is connected with the washing lotion on-off valve, and liquid sucking device is connected with the waste liquid on-off valve; Described washing lotion peristaltic pump is connected with the outlet of washing lotion bucket; Described waste liquid peristaltic pump is connected with the inlet of waste liquid barrel.
The priming device of described automatic flushing device and liquid sucking device, the washing lotion on-off valve, and the quantity of waste liquid on-off valve is identical and be more than one; And between described washing lotion peristaltic pump and the washing lotion on-off valve, be equipped with the stream joint between described waste liquid on-off valve and the waste liquid peristaltic pump.
Described washing lotion bucket is the hydrophobic material material.
Described waste liquid barrel is the hydrophobic material material.
The utility model compared with prior art has following advantage and beneficial effect:
1, the structure of robotization has been avoided manual uncertainty, has improved detection efficiency and experiment flux.
2, the system integration is convenient in multi-functional mechanism, can invent the equipment that forms more automation functions on the basis at this.
Description of drawings
Fig. 1 is the utility model structural representation.
Fig. 2 is the structural representation of a kind of embodiment of the utility model.
Fig. 3 is the structural representation of present embodiment pin cleaning device.
Fig. 4 be the present embodiment automatic flushing device structural representation.
Mark and corresponding component names in the accompanying drawing: 1-washing lotion bucket, automatic application of sample of 2-and sample pin purging system, 3-waste liquid barrel, 4-reaction tube purging system, 21-expresses pump, the 22-syringe pump, the 23-T-valve, the automatic sample adding device of 24-, 25-pin cleaning device, 241-sample pin, 242-motion, 251-are washed the pin district, the 252-discharge region, 51-washing lotion peristaltic pump, 52-waste liquid peristaltic pump, 6-stream joint, 71-washing lotion on-off valve, 72-waste liquid on-off valve, the 8-automatic flushing device, 81-base, 82-evenly mixing device, the 83-top board, 84-reaction tube support, 85-liquid sucking device, the 86-column, the 87-priming device, 88-vertical table, 89-horizontal table.
Embodiment
The utility model is described in further detail below in conjunction with embodiment, but embodiment of the present utility model is not limited thereto.
Embodiment
As shown in Figure 1, a kind of flow path system that is used for automatic biological chemical reaction flow process comprises washing lotion bucket 1, automatic application of sample and sample pin purging system 2, waste liquid barrel 3, and reaction tube purging system 4; Respectively with automatically application of sample and sample pin purging system, reaction tube purging system are connected in two outlets of described washing lotion bucket; Respectively with automatically application of sample and sample pin purging system 2, reaction tube purging system 4 are connected in two imports of described waste liquid barrel.
Washing lotion bucket carrying cleaning fluid, waste liquid barrel carrying waste liquid.Automatically application of sample and sample pin purging system can use sample pin application of sample automatically, and application of sample finishes to extract cleaning fluid automatically from the washing lotion bucket sample pin is cleaned, and the waste liquid after will cleaning enters in the waste liquid barrel.Simultaneously, the reaction tube purging system can extract cleaning fluid from the washing lotion bucket automatically reaction tube is cleaned, and cleaning fluid is entered waste liquid barrel.
As shown in Figure 2, in the present embodiment, described automatic application of sample and sample pin purging system 2 comprise and express pump 21, syringe pump 22, T-valve 23, sample adding device 24 and pin cleaning device 25 automatically; Described automatic sample adding device 24 comprises sample pin 241, and the motion that moves up and down and rotatablely move 242 of control sample pin; First joint of described T-valve is connected with syringe pump, second joint with express delivery side of pump and be connected, the 3rd joint is connected with the sample pin of sample adding device automatically; The described input end that expresses pump is connected with the washing lotion bucket; Described pin cleaning device 25 is connected with waste liquid barrel 3.
Three joints of described T-valve connect syringe pump respectively, express pump output terminal and sample pin.Wherein syringe pump and sample pin express between pump output terminal and the sample pin and can distinguish conducting.When syringe pump and sample needle guide are logical, can draw and discharge sample; When expressing pump output terminal and sample needle guide when logical, can with washing lotion bucket that its input end is connected in cleaning fluid be pumped in the sample pin and discharge fast, reach the purpose of cleaning sample pin inwall; Described pin cleaning device can be kept in the cleaning fluid that part bursts out, and is used to clean sample pin outer wall.
As shown in Figure 3, a kind of embodiment of pin cleaning device.The pin cleaning device is the container that the sample pin cleans, and it comprises washes pin district 251, discharge region 252.Washing the pin district is an elongated cylinder type structure, and discharge region is the cylindrical structure that interior cover is washed the pin district, and the bottom connects waste liquid barrel.
The motion of described robotization sample adding device 24 can comprise elevating mechanism, rotating mechanism, its collaborative running is accurately located the sample pin that connects, make the sample pin can move to correct position, the operation of draw sample in the tram, discharging sample, cleaning sample hose.
Automatically the workflow of application of sample and Rapid Cleaning system is: syringe pump that T-valve connects and sample needle guide are logical, the sample pin is drawn and the emissions object sample, the sample pin inserts the pin cleaning device under the control of its motion afterwards, the pump that expresses that connect in the T-valve this moment leads to the sample needle guide, express pump the cleaning fluid in the connected washing lotion bucket is pumped into the sample pin in a large number, discharge washing in the pin district of pin cleaning device fast by the sample pin, a large amount of cleaning fluids can clean sample pin inwall fast and effectively, its washing lotion that gives off can be cleaned sample pin outer wall washing the accumulation of pin district.After the capacity of washing the pin district was full, washing lotion can be overflowed and be washed the pin district and enter the discharge region of washing outer ring, pin district, and then washing lotion enters waste liquid barrel by discharge region.
Described reaction tube purging system comprises washing lotion peristaltic pump 51, washing lotion on-off valve 71, automatic flushing device 8, waste liquid on-off valve 72, the waste liquid peristaltic pump 52 that connects successively.
As shown in Figure 4, be a kind of embodiment of automatic flushing device.The top board 83 that described automatic flushing device comprises the column 86 of base 81, relatively base vertical movement, be connected with base by column, be fixed on the vertical table 88 on the base and be connected horizontal table 89 on the vertical table, lower surface at horizontal table is equipped with the reaction tube support 84 that moves relative to horizontal table, horizontal table is provided with liquid injection hole and imbibing hole, priming device 87 is installed above liquid injection hole, evenly mixing device 82 is installed under priming device, and top board is provided with the liquid sucking device 85 that passes imbibing hole.The reaction tube support is suspended on the bottom of horizontal table and can moves with respect to horizontal table, be placed on reaction tube on the reaction tube support in the moving process of horizontal table, move to the evenly mixing device position, evenly mixing device is connected to priming device with the reaction tube mouth of pipe, priming device is injected the cleaning fluid that extracts from the washing lotion bucket in reaction tube, evenly mixing device rocks reaction tube, after solid that it is inner and cleaning fluid evenly mix, evenly mixing device and reaction tube break away from, the reaction tube support drives the below that reaction tube moves to liquid sucking device, the liquid sucking device that is arranged on the top board is stretching under the drive of column below the liquid level of reaction tube, and begin to draw liquid in the reaction tube, so, just, finish once cleaning to reaction tube.
The priming device of described automatic flushing device is connected with the washing lotion on-off valve, and liquid sucking device is connected with the waste liquid on-off valve; Described washing lotion peristaltic pump is connected with the outlet of washing lotion bucket; Described waste liquid peristaltic pump is connected with the inlet of waste liquid barrel.On-off valve can operation valve connects the break-make at two ends, the break-make when washing lotion on-off valve control priming device extracts washing lotion, the break-make when waste liquid on-off valve control liquid sucking device is drawn waste liquid from reaction tube.When the reaction tube fluid injection, the washing lotion peristaltic pump that is connected with the washing lotion bucket just changes, and the cleaning fluid in the washing lotion bucket that connects pumps into priming device; During from the reaction tube imbibition, the waste liquid peristaltic pump counter-rotating that is connected with waste liquid barrel pumps into the waste liquid of drawing in the waste liquid barrel of its connection.
During concrete enforcement, the priming device of described automatic flushing device and the quantity of liquid sucking device can be provided with more than one, can clean a plurality of reaction tubes simultaneously.Adapt with it, the washing lotion on-off valve, and the quantity of waste liquid on-off valve also is more than one, and quantity is identical with the quantity of priming device or washing lotion device; And between described washing lotion peristaltic pump and the washing lotion on-off valve, all set up stream joint 6 between described waste liquid on-off valve and the waste liquid peristaltic pump.The stream joint is the structure of one-to-many, has single input to change and exports and two kinds of structures of many input commentaries on classics list outputs more.The stream joint input end that many export structures are changeed in single input connects the washing lotion peristaltic pump, and output terminal connects priming device; The stream joint input end that single export structure is changeed in many inputs connects liquid sucking device, and output terminal connects the waste liquid peristaltic pump.
Further, described washing lotion bucket is the hydrophobic material material.
Further, described waste liquid barrel is the hydrophobic material material.
As mentioned above, just can realize the utility model well.

Claims (6)

1. a flow path system that is used for automatic biological chemical reaction flow process is characterized in that: comprise washing lotion bucket (1), automatic application of sample and sample pin purging system (2), waste liquid barrel (3) and reaction tube purging system (4); Respectively with automatically application of sample and sample pin purging system, reaction tube purging system are connected in two outlets of described washing lotion bucket; Respectively with automatically application of sample and sample pin purging system, reaction tube purging system are connected in two imports of described waste liquid barrel.
2. a kind of flow path system that is used for automatic biological chemical reaction flow process according to claim 1, it is characterized in that described automatic application of sample and sample pin purging system (2) comprise and express pump (21), syringe pump (22), T-valve (23), sample adding device (24) and pin cleaning device (25) automatically; Described automatic sample adding device (24) comprises sample pin (241), and controls the motion (242) that the sample pin moves up and down and rotatablely moves; First joint of described T-valve is connected with syringe pump, second joint with express delivery side of pump and be connected, the 3rd joint is connected with the sample pin of sample adding device automatically; The described input end that expresses pump is connected with the washing lotion bucket; Described pin cleaning device (25) is connected with waste liquid barrel (3).
3. a kind of flow path system that is used for automatic biological chemical reaction flow process according to claim 1, it is characterized in that described reaction tube purging system comprises washing lotion peristaltic pump (51), washing lotion on-off valve (71), automatic flushing device (8), waste liquid on-off valve (72), the waste liquid peristaltic pump (52) that connects successively; Described automatic flushing device comprises base (81), the column (86) of relative base vertical movement, the top board (83) that is connected with base by column, be fixed on the vertical table (88) on the base, and be connected horizontal table (89) on the vertical table, lower surface at horizontal table is equipped with the reaction tube support (84) that moves relative to horizontal table, horizontal table is provided with liquid injection hole and imbibing hole, priming device (87) is installed above liquid injection hole, evenly mixing device (82) is installed under priming device, and top board is provided with the liquid sucking device (85) that passes imbibing hole; The priming device of described automatic flushing device is connected with the washing lotion on-off valve, and liquid sucking device is connected with the waste liquid on-off valve; Described washing lotion peristaltic pump is connected with the outlet of washing lotion bucket; Described waste liquid peristaltic pump is connected with the inlet of waste liquid barrel.
4. a kind of flow path system that is used for automatic biological chemical reaction flow process according to claim 1, it is characterized in that, the priming device of described automatic flushing device and liquid sucking device, the washing lotion on-off valve, and the quantity of waste liquid on-off valve is identical and be more than one; And between described washing lotion peristaltic pump and the washing lotion on-off valve, be equipped with stream joint (6) between described waste liquid on-off valve and the waste liquid peristaltic pump.
5. a kind of flow path system that is used for automatic biological chemical reaction flow process according to claim 1 is characterized in that described washing lotion bucket is the hydrophobic material material.
6. a kind of flow path system that is used for automatic biological chemical reaction flow process according to claim 1 is characterized in that described waste liquid barrel is the hydrophobic material material.
CN2011200376007U 2011-02-14 2011-02-14 Flow path system for automation biochemical reaction flow Expired - Lifetime CN201965136U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011200376007U CN201965136U (en) 2011-02-14 2011-02-14 Flow path system for automation biochemical reaction flow

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Application Number Priority Date Filing Date Title
CN2011200376007U CN201965136U (en) 2011-02-14 2011-02-14 Flow path system for automation biochemical reaction flow

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102430549A (en) * 2011-12-15 2012-05-02 深圳市尚荣医疗股份有限公司 Cleaning device for full-automatic biochemical analyzer and cleaning method thereof
CN105929124A (en) * 2016-06-12 2016-09-07 深圳市清时捷科技有限公司 On-line water quality analysis instrument and water quality analysis method thereof
CN109675872A (en) * 2019-01-16 2019-04-26 深圳迎凯生物科技有限公司 Clean separation system
CN112378863A (en) * 2020-09-30 2021-02-19 深圳市朗诚科技股份有限公司 Water quality analysis method of water quality analyzer

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102430549A (en) * 2011-12-15 2012-05-02 深圳市尚荣医疗股份有限公司 Cleaning device for full-automatic biochemical analyzer and cleaning method thereof
CN102430549B (en) * 2011-12-15 2013-10-23 深圳市尚荣医疗股份有限公司 Cleaning device for full-automatic biochemical analyzer and cleaning method thereof
CN105929124A (en) * 2016-06-12 2016-09-07 深圳市清时捷科技有限公司 On-line water quality analysis instrument and water quality analysis method thereof
CN109675872A (en) * 2019-01-16 2019-04-26 深圳迎凯生物科技有限公司 Clean separation system
CN112378863A (en) * 2020-09-30 2021-02-19 深圳市朗诚科技股份有限公司 Water quality analysis method of water quality analyzer

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Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract

Assignee: SICHUAN MAKER BIOMEDICAL ELECTRONIC CO., LTD.

Assignor: Sichuan Maker Biological Science and Technology Co., Ltd.

Contract record no.: 2014510000174

Denomination of utility model: Flow path system for automation biochemical reaction flow

Granted publication date: 20110907

License type: Common License

Record date: 20141112

LICC Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model
CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20110907