CN114796059B

CN114796059B - Moisturizing and repairing composition, skin care product and skin care product preparation method

Info

Publication number: CN114796059B
Application number: CN202210593829.1A
Authority: CN
Inventors: 郑中博; 陆徐佳; 张浩洋; 贾兵; 李晞暘; 刘陈陈
Original assignee: Huzhou Jiaheng Industrial Co ltd
Current assignee: Huzhou Jiaheng Industrial Co ltd
Priority date: 2022-05-27
Filing date: 2022-05-27
Publication date: 2023-08-25
Anticipated expiration: 2042-05-27
Also published as: CN114796059A

Abstract

The application provides a moisturizing repair composition which comprises the following components in parts by weight: sodium bis (lauramide glutamine) lysine: 1-5 parts of kava root extract: 1-10 parts of Fucus vesiculosus extract: 1-5 parts. The application also provides a moisturizing and repairing skin care product which comprises the components. The application also provides a preparation method of the moisturizing and repairing skin care product. The sodium bis (lauramide glutamine) lysine, the kava root extract and the fucus extract are adopted for synergistic combination, and the sodium bis (lauramide glutamine) lysine can penetrate through the stratum corneum and form a lamellar crystal structure in intercellular lipid so as to achieve the repairing effect.

Description

Moisturizing and repairing composition, skin care product and skin care product preparation method

Technical Field

The application relates to a cosmetic and a preparation method thereof, in particular to a moisturizing and repairing composition, a skin care product and a preparation method of the skin care product.

Background

With the improvement of living standard of people, skin care is getting more and more attention, and moisturizing is the most important effect of cosmetics and is also the basis of skin care. Sufficient skin moisture is critical to healthy skin, and sufficient hydration facilitates enzymatic reactions and promotes maturation of the stratum corneum and maintains its elasticity.

In the contact between human body and outside, the skin also plays a role of a barrier, and can prevent the damage of external chemical, physical, mechanical, biological and other factors to the skin, and can prevent the loss of moisture and nutrient substances. Factors that cause damage to the skin barrier are numerous, such as excessive cleaning, use of irritating cosmetics, harsh environments, and the like. Skin barrier damage is involved in the occurrence of a variety of skin problems, and therefore, the efficacy of repairing skin barriers is also an important direction in the development of skin care products.

The existing moisturizing repair skin care product mainly realizes a moisturizing repair function by adding ceramide, such as a composition and a cosmetic with a moisturizing repair effect disclosed in Chinese patent application publication No. CN 113616561A, a moisturizing repair cream disclosed in Chinese patent application publication No. CN 112870123A, a preparation method and application thereof, a moisturizing repair composition disclosed in Chinese patent application publication No. CN 112842985A and the like. Although ceramide is a substance which can be secreted and synthesized by a human body, if the ceramide is supplemented by an exogenous source for a long time, extremely strong dependence is caused, the capacity of the ceramide secreted by the cell can not be regulated fundamentally, the self synthesis and secretion capacity can be weakened, and once the ceramide is not supplemented, more serious damage to the epidermis barrier can be caused, in addition, the raw material price of the ceramide is relatively high, and the cost of moisturizing and repairing skin care products is relatively high.

In view of the above, the present inventors have conducted intensive studies on the above problems and have made the present application.

Disclosure of Invention

The application aims to provide a moisturizing repair composition, a skin care product and a skin care product preparation method, wherein the moisturizing repair composition is not easy to generate dependence after long-term use and has relatively low cost.

In order to achieve the above purpose, the present application adopts the following technical scheme:

the moisturizing repair composition comprises the following components in parts by weight,

sodium bis (lauramide glutamine) lysine: 1-5 parts of a compound, wherein,

kava root extract: 1-10 parts of a compound containing,

fucus vesiculosus extract: 1-5 parts.

A moisturizing and repairing skin care product comprises the following components in percentage by mass,

Pellicer L-30：0.3-1.7％，

DCR516：0.1-1％，

ink phycocolloid-H: 2 to 10 percent,

an auxiliary material matrix: 88% -95%.

As a further development of the application, the adjuvant matrix comprises water.

As a further improvement of the present application, the adjuvant matrix further includes one or more of moisturizer, emollient, emulsifier, thickener, skin conditioner, preservative, fragrance, and pH adjustor.

As a further improvement of the application, the auxiliary material matrix comprises the following components in percentage by mass,

humectant: 2-20 percent,

an emollient: 0.3 to 25 percent,

emulsifying agent: 0.1-4%,

and (3) a thickening agent: 0.1-2%,

skin conditioning agent: 0.1-10 percent,

preservative: 0-1%,

fragrance: 0 to 0.3 percent,

pH regulator: 0-1%,

water: the balance of which.

As a further improvement of the application, the humectant is glycerin and/or glycerin polyether-26; the emollient is one or more than two of squalane, caprylic acid/capric acid triglyceride, dioctyl carbonate, hydrogenated polyisobutene and butter fruit tree fruit fat; the emulsifier is one or more than two of PEG-40 hydrogenated castor oil, hydrogenated lecithin and glycerol stearate citrate; the thickener is one or more than two of carbomer, acrylic acid (ester) or C10-30 alkanol acrylate cross-linked polymer, sodium polyacrylate and xanthan gum; the skin conditioning agent is nicotinamide and/or tetrahydromethylpyrimidine carboxylic acid; the preservative is sodium benzoate and/or phenoxyethanol; the aromatic is essence; the pH regulator is aminomethyl propanol and/or citric acid.

A preparation method of a moisturizing and repairing skin care product comprises the following steps sequentially carried out,

s1, respectively adding 50-84% by mass of water and 0.3-1.7% by mass of Pellicer L-30 into a water phase pot, stirring until the water phase pot is completely and uniformly dispersed, adding the solution in the water phase pot into a main pot, and heating to 70-80 ℃;

s2, respectively adding 0.3-25% by mass of an emollient and 0.1-4% by mass of an emulsifier into an oil phase pot, heating to 75 ℃, stirring until the mixture is uniform, and pumping the solution in the oil phase pot into the main pot under a homogenizing condition;

s3, cooling the temperature of the main pot to below 50 ℃, then adding 0.1-1% of DCR516 and 2-10% of fucoidan-H in percentage by mass into the main pot respectively, and stirring until the materials are uniformly mixed to obtain the moisturizing and repairing skin care product.

As a further improvement of the application, in step S1, a thickener in an amount of 0.1 to 2% by mass and a humectant in an amount of 2 to 20% by mass are simultaneously added to the aqueous phase pot.

As a further improvement of the present application, in step S2, 0.1 to 10% by mass of a skin conditioning agent, 0 to 1% by mass of a preservative, 0 to 0.3% by mass of a fragrance, and 0 to 1% by mass of a pH adjuster are simultaneously added to the main pot.

By adopting the technical scheme, the application has the following beneficial effects:

1. the sodium bis (lauramide glutamine) lysine, the kava root extract and the fucus extract are adopted for synergistic combination, so that the sodium bis (lauramide glutamine) lysine can penetrate through the stratum corneum and form a lamellar crystal structure in intercellular lipid to achieve the repairing effect, and the effects of improving skin tolerance and relieving irritation of the kava root extract are matched, and the efficient moisturizing effect of the fucus extract is added, so that the moisture content of the skin of the stratum corneum is remarkably improved, the stratum corneum barrier of the skin is repaired, and the long-term use is difficult to produce dependence and the cost is relatively low because ceramide is not needed.

2. Since the main ingredient of Pellicer L-30 is sodium bis (lauramide glutamine) lysine, DCR516 contains 90-100% of kava root extract, and the main ingredient of fucoidan-H is fucoidan extract, the skin care product of the application also has the effects of moisturizing and repairing of the composition, and is not easy to generate dependence after long-term use and relatively low in cost.

3. The three key raw materials of the application have the characteristics of convenient process, easy acceptance of cost and the like through synergistic effect, scientific proportioning and reasonable dosage, and can achieve the effects of moisturizing and repairing.

Drawings

Fig. 1 is an experimental result based on the zebra fish model in the example.

Detailed Description

The application will be further illustrated with reference to specific examples, wherein the raw materials and test equipment used in the following examples and comparative examples are commercially available, and wherein the test steps or test steps, which are not specified in the specific conditions, are carried out according to conventional conditions or according to the conditions recommended by the manufacturers of test equipment, and will not be described in detail herein. In addition, all percentages are by mass unless otherwise indicated.

The application provides a moisturizing repair composition which comprises the following components in parts by weight:

sodium bis (lauramide glutamine) lysine: 1-5 parts of a compound, wherein,

kava root extract: 1-10 parts of a compound containing,

fucus vesiculosus extract: 1-5 parts.

The composition is compounded by adopting specific raw materials, wherein the Fucus vesiculosus extract helps the stratum corneum to absorb moisture and form an invisible moisturizing film on the skin surface, sodium bis (lauramide glutamine) lysine can penetrate the stratum corneum and form a flaky crystal structure in intercellular lipid to achieve the repairing effect, and the kava root extract can remarkably improve the skin tolerance and relieve the irritation, so that the composition can be widely applied to various skin care products.

The application also provides a moisturizing and repairing skin care product containing the composition, which comprises the following components in percentage by mass:

Pellicer L-30：0.3-1.7％，

DCR516：0.1-1％，

ink phycocolloid-H: 2 to 10 percent,

an auxiliary material matrix: 88% -95%.

Among the above components, pellicer L-30, DCR516 and fucoidan-H are all raw material trade names and are directly purchased from the market, wherein the main component of Pellicer L-30 is sodium bis (lauramidoglutamine) lysine, and specifically consists of 29% sodium bis (lauramidoglutamine) lysine and 71% water; DCR516 contains 90-100% kava root extract, wherein the active ingredient name is 2000-3000ppm kavain (cas: 3155-48-4); the main component of the fucoidan-H is fucoidan extract, which is composed of 83.5% of water, 10% of glycerol, 5% of fucoidan extract, 0.5% of butanediol, 0.5% of 1, 2-hexanediol and 0.5% of p-hydroxyacetophenone.

Among the above components, the auxiliary material matrix comprises water, which can be deionized water or other water meeting the requirements of daily chemical manufacturers, and is not described in detail herein. The auxiliary material matrix also comprises one or more than two of humectant, emollient, emulsifier, thickener, skin conditioner, preservative, aromatic and pH regulator, and can be specifically selected according to actual needs, in this embodiment, the auxiliary material matrix comprises the following components in percentage by mass:

humectant: 2-20 percent,

an emollient: 0.3 to 25 percent,

emulsifying agent: 0.1-4%,

and (3) a thickening agent: 0.1-2%,

skin conditioning agent: 0.1-10 percent,

preservative: 0-1%,

fragrance: 0 to 0.3 percent,

pH regulator: 0-1%,

water: the balance of which.

Preferably, in this embodiment, the humectant is glycerin and/or glycerin polyether-26; the emollient is one or more of squalane, caprylic/capric triglyceride, dioctyl carbonate, hydrogenated polyisobutene, and butter fruit of Butyrospermum parkii; the emulsifier is one or more of PEG-40 hydrogenated castor oil, hydrogenated lecithin and glyceryl stearate citrate; the thickener is one or more of carbomer, acrylic acid (esters) or C10-30 alkanol acrylate cross-linked polymer, sodium polyacrylate and xanthan gum; the skin conditioning agent is nicotinamide and/or tetrahydromethyl pyrimidine carboxylic acid; the preservative is sodium benzoate and/or phenoxyethanol; the aromatic is essence, and the aroma is one or more than two of floral aroma, fruit aroma and costustoot; the pH regulator is aminomethyl propanol and/or citric acid.

The application also provides a preparation method of the moisturizing and repairing skin care product, which comprises the following steps in sequence:

s1, respectively adding 50-84% by mass of water, 0.1-2% by mass of thickener, 2-20% by mass of humectant and 0.3-1.7% by mass of Pellicer L-30 into a water phase pot, stirring until the materials are completely and uniformly dispersed, adding the solution in the water phase pot into a main pot, and heating to 70-80 ℃.

S2, respectively adding 0.1-10% of skin conditioning agent, 0-1% of preservative, 0-0.3% of aromatic, 0-1% of pH regulator, 0.3-25% of emollient and 0.1-4% of emulsifier into an oil phase pot, heating to 75 ℃ (a certain temperature error is allowed, for example, 5 ℃ error exists), stirring until the mixture is uniform, pumping the solution in the oil phase pot into a main pot under a homogeneous condition (under the condition of homogeneity, the stirring speed is 1500-3000rpm, so as to ensure that the pumped solution is uniform), and controlling the pressure of the main pot to realize pumping under negative pressure, wherein the specific pressure of the main pot is as follows: minus 0.05MPa to minus 0.09MPa.

S3, cooling the temperature of the main pot to below 50 ℃ by adopting circulating cooling water, then respectively adding 0.1-1% of DCR516 and 2-10% of fucoidan-H in the main pot, and stirring until the materials are uniformly mixed to obtain the moisturizing repair skin product, wherein the moisturizing repair skin product can be a moisturizing repair essence, moisturizing repair body cream, moisturizing repair essence, moisturizing repair eye cream, moisturizing repair essence cream, moisturizing repair mask and other product types.

The preparation method adopts different formulas to prepare and obtain a plurality of examples as follows:

example 1, moisturizing repair essence.

The skin care product of example 1 was prepared according to the formulation shown in table 1 below, and the skin care product was a moisturizing repair essence, while five moisturizing essences were prepared according to the formulation shown in table 1 below as comparative examples (comparative examples), comparative examples 1 to 5, respectively. In the preparation of the comparative examples, if the components to be added in the preparation method are not in the formulations shown in table 1 below, the corresponding components are not added at the time of preparation.

Table 1: formulation composition (%)

The six types of moisturizing essences are detected, and specific detection items, methods and results are as follows:

(1) Stability test, the moisturizing repair essence prepared in comparative examples 1 to 5 and example 1 were placed at room temperature, 45 ℃ and-10 ℃ respectively, and the samples were examined for 7 days to see if there was delamination, and if there was no change in the samples before and after the specified time, the samples were marked as "ok", and if the delamination was marked as "unstable", the results are shown in table 2 below.

Table 2: stability investigation of moisturizing repair essence

Sample source	Room temperature	45℃	-10℃
				Comparative example 1	ok	ok	ok
Comparative example 2	ok	ok	ok
				Comparative example 3	ok	ok	ok
Comparative example 4	ok	ok	ok
				Comparative example 5	ok	ok	ok
Example 1	ok	ok	ok

As can be seen from Table 2 above, each of the moisturizing repair essence samples was left for 7 days at room temperature, 45℃and-10℃respectively, without delamination, indicating that the formulation of this system was structurally stable.

(2) For the continuous moisturizing effect detection of the skin horny layer of the arm, comparative examples 1 to 5 and example 1 are respectively used for consumers (human bodies), the moisturizing repair essence samples are used before, after 1h, after 2h, after 4h and after 8h (wherein h is time unit hour), the continuous moisturizing effect of the skin horny layer on the inner side of the front arm of the subject is detected by adopting a moisture content tester (the moisture content test model adopted in the embodiment is Corneometer CM 825), and particularly, the skin is smeared on the skin surface, the continuous moisturizing effect is carried out on the skin horny layer moisture, the effect is gradually weakened along with the change of time, the skin horny layer moisture is tracked and measured in a specified time, and the moisturizing effect of the skin horny layer moisture by the samples can be evaluated. Stratum corneum moisture content measurement, based on capacitance principle, the larger the value, the higher the stratum corneum moisture content. The results are shown in table 3 below, where the blank is a consumer (human) without any moisturizing repair concentrate samples.

Table 3: skin moisture content test values at different time points (a.u.)

Sample source	T 0	T(1h)	T(2h)	T(4h)	T(8h)
						Blank control	32.1	32.3	33.6	33.4	31.5
Comparative example 1	32.2	35.1	34.9	33.8	32.5
						Comparative example 2	32.1	39.2	38.8	37.6	37.1
Comparative example 3	32.5	42.1	41.1	39.5	37.8
						Comparative example 4	32.3	44.8	43.2	41.8	38.1
Comparative example 5	32.6	43.2	42.5	40.6	38.0
						Example 1	32.8	47.8	47.0	43.0	39.8

From the blank and the results of comparative example 1, it is clear that the moisturizing repair composition is not added to the formulation, only 1% of the glyceryl polyether-26 is used as a moisturizing agent, and the product has no moisturizing effect. As is clear from the results of comparative example 2, when the amount of the glyceryl polyether-26 was increased to 5%, the product had a certain moisturizing effect but the effect was not strong. As is clear from the results of comparative example 3, the moisturizing effect was significantly improved by selecting glycerolyether-26 as the moisturizing agent and by adding 5% of fucoidan-H as the moisturizing and repairing component, which indicates that the fucoidan extract plays a decisive role in moisturizing. As is clear from the results of comparative example 4, it was confirmed that the moisturizing effect was enhanced to some extent by adding Pellicer L-30 as a moisturizing and repairing composition, and the effect of 1+1>2 was demonstrated. As is evident from the results of comparative example 5, the addition of DCR516 had substantially no effect on moisturizing efficacy. The results of example 1 show that the simultaneous addition of Pellicer L-30 and DCR516 has a remarkable synergistic effect on the moisturizing effect, and demonstrate that the skin-soothing and sodium bis (lauramide glutamine) lysine amphiphilic structure of kava root extract plays an important role in further exerting the moisturizing effect.

(3) The continuous moisturizing effect test of the skin horny layer of the face was carried out by measuring the transepidermal water loss rate of the skin by using comparative example 3, comparative example 5 and example 1 for consumers (human bodies), respectively, to determine the moisturizing and repairing effect of the moisturizing and repairing essence on the skin horny layer of the face. Specifically, the open skin transepidermal water loss index (tewatter TM HEX) of the subject's facial skin was measured 14 days after and 28 days after use, before use, and the open skin transepidermal water loss tester evaluated the skin barrier function based on Fick's law of diffusion, the greater the value, the more severe the impaired the skin barrier function. The results are shown in Table 4 below.

Table 4: skin transepidermal water loss rate detection values (g/cm 2. H) at different time points

Sample source	D 0	D 14	D 28
				Comparative example 3	23.88	21.85	20.08
Comparative example 4	23.78	20.51	19.85
				Example 1	23.83	19.95	18.41

As is clear from the results of comparative example 3, only 5% of fucoidan-H was added to the formulation, and the moisturizing effect was limited. As is clear from the results of comparative example 4, the repairing effect is significantly improved by adding Pellicer L-30 to the formulation of comparative example 3, which indicates that sodium di (lauramidoglutamine) lysine can penetrate the stratum corneum and form a lamellar crystal structure in intercellular lipid to play a critical role in repairing effect. The results of example 1 show that the simultaneous addition of Pellicer L-30 and DCR516 has a remarkable synergistic effect on the repairing effect, because the amphiphilic molecular structure of sodium lysine bis (lauramide glutamine) promotes the skin barrier function and skin health, effectively reduces the transdermal water loss rate, and the cooperation of the fucus extract helps the stratum corneum to absorb water and form a invisible moisturizing film on the skin surface and the kava root extract can remarkably improve the skin tolerance and relieve the irritation. The three key raw materials have sufficient moisturizing and repairing effects on the skin through synergistic effect and scientific proportioning.

Example 2 preparation of moisturizing repair essence.

According to the preparation method, 87.9% of water, 0.5% of Pellicer L-30, 0.15% of xanthan gum and 5% of glycerol are added into a water phase pot, stirred until the mixture is completely and uniformly dispersed, then the water phase pot is added into the main pot, the temperature is raised and heated to 70-80 ℃, then 0.3% of squalane and 0.15% of PEG-40 hydrogenated castor oil are added into an oil phase pot, heated and stirred to be uniformly mixed, and then the mixture is pumped into the main pot under the condition of homogenization; then cooling the main pot to below 50 ℃, adding 2% of nicotinamide, 0.3% of tetrahydropyrimidine carboxylic acid, 0.3% of DCR516, 3% of fucoidan-H and 0.4% of phenoxyethanol, stirring until the materials are uniformly mixed, and preparing the moisturizing and repairing essence water.

Example 3 preparation of moisturizing repair essence.

According to the preparation method, 86.45% of water, 0.6% of Pellicer L-30, 0.2% of sodium polyacrylate and 5% of glycerolyether-26 are added into a water phase pot, stirred until the mixture is completely and uniformly dispersed, then the mixture is added into a main pot, and the temperature is raised and heated to 70-80 ℃. Adding 0.5% of caprylic/capric triglyceride and 0.15% of sodium methyl stearyl taurate into an oil phase pot, heating and stirring to uniformly mix, and then pumping into a main pot under a homogenizing condition; and then cooling the main pot to below 50 ℃, adding 3% of nicotinamide, 0.5% of tetrahydropyrimidine carboxylic acid, 0.2% of DCR516, 3% of fucoidan-H and 0.4% of sodium benzoate, and stirring until the materials are uniformly mixed, thus finishing the preparation of the moisturizing and repairing essence.

Example 4 preparation of moisturizing repair essence emulsion.

According to the preparation method, 72.77% of water, 1% of Pellicer L-30, 0.3% of acrylic acid (ester) or C10-30 alkanol acrylate cross-linked polymer and 6% of glycerolyether-26 are added into a water phase pot, stirred until the mixture is completely and uniformly dispersed, then the mixture is added into a main pot, and the temperature is raised and heated to 70-80 ℃. Adding 2% of squalane, 3% of hydrogenated polyisobutene, 3% of shea butter and 2% of glycerol stearate citrate into an oil phase pot, heating and stirring to uniformly mix, and pumping into a main pot under a homogenizing condition; then cooling the main pot to below 50 ℃, adding 0.1% dipotassium glycyrrhizinate, 3% nicotinamide, 0.4% tetrahydropyrimidine carboxylic acid, 0.8% DCR516, 5% fucoidan-H, 0.4% phenoxyethanol, 0.08% essence and 0.15% aminomethylpropanol, stirring until the materials are uniformly mixed, and completing the preparation of the moisturizing and repairing essence emulsion.

Example 5 preparation of moisturizing repair mask.

According to the preparation method, 88.67% of water, 0.3% of Pellicer L-30, 0.2% of carbomer, 0.3% of sodium polyacrylate and 5% of glycerin are added into a water phase pot, stirred until the mixture is completely and uniformly dispersed, then the mixture is added into a main pot, and the temperature is raised and heated to 70-80 ℃. Adding 0.5% dioctyl carbonate and 0.15% PEG-40 hydrogenated castor oil into an oil phase pot, heating and stirring until the mixture is uniform, and then pumping into a main pot under the condition of homogenization; then cooling the main pot to below 50 ℃, adding 2% of nicotinamide, 0.15% of tetrahydropyrimidine carboxylic acid, 0.2% of DCR516, 2% of fucoidan-H, 0.4% of phenoxyethanol, 0.08% of essence and 0.05% of sodium citrate, stirring until the materials are uniformly mixed, and finishing the preparation of the moisturizing and repairing mask.

Example 6 preparation of moisturizing repair mask.

According to the preparation method, 67.52% of water, 0.5% of Pellicer L-30, 0.4% of xanthan gum, 0.4% of acrylic acid (esters) or C10-30 alkanol acrylate cross-linked polymer and 8% of glycereth-26 are added into a water phase pot, stirred until the mixture is completely and uniformly dispersed, then the mixture is added into a main pot, and the temperature is raised and heated to 70-80 ℃. Adding 3% of squalane, 3% of hydrogenated polyisobutene, 4% of butter tree fruit fat, 3% of glycerol stearate citrate and 0.6% of PEG-40 hydrogenated castor oil into an oil phase pot, heating and stirring to uniformly mix, and pumping into a main pot under a homogenizing condition; and then cooling the main pot to below 50 ℃, adding 4% of nicotinamide, 0.4% of tetrahydropyrimidine carboxylic acid, 0.5% of DCR516, 4% of fucoidan-H, 0.4% of phenoxyethanol, 0.08% of essence and 0.2% of aminomethylpropanol, and stirring until the materials are uniformly mixed, thereby completing the preparation of the moisturizing repair face cream.

The moisturizing and repairing effects of the skin care products prepared in examples 2 to 6 were evaluated based on a zebra fish model. Neutrophil and macrophage overactivation and infiltration are the pathological basis of chronic inflammation and other inflammation-related diseases, so that the neutrophil and macrophage at the inflammation part can be cleared to effectively reduce inflammatory response, the promotion effect of moisturizing repair products on the clearance of neutrophil and macrophage at the inflammation part can be studied by using the zebra fish to manufacture a tail-cutting inflammation model, and the specific experimental flow is as follows: the zebra fish tail fin is cut off to manufacture an inflammation model, zebra fish with the cell aggregation number of about 30 cells is selected after 6 hours, and then the zebra fish is treated by the skin care product prepared in the examples 2-6 for 6 hours, the experimental results are shown in the figure 1, and the results show that the skin care products prepared in the examples 2-6 can promote the reverse migration of neutrophils and macrophages at the wound of the zebra fish or induce the apoptosis of the neutrophils and the macrophages, and can play the anti-inflammatory repair role.

Example 7 preparation of moisturizing repair face serum.

According to the preparation method, 86.95% of water, 0.3% of Pellicer L-30, 0.2% of sodium polyacrylate and 5% of glycereth-26 are added into a water phase pot, stirred until the mixture is completely and uniformly dispersed, then the mixture is added into a main pot, and the temperature is raised and heated to 70-80 ℃. Adding 0.5% of caprylic/capric triglyceride and 0.15% of sodium methyl stearyl taurate into an oil phase pot, heating and stirring to uniformly mix, and then pumping into a main pot under a homogenizing condition; cooling the main pot to below 50 ℃, adding 3% of nicotinamide, 0.5% of tetrahydropyrimidine carboxylic acid, 1% of DCR516, 2% of fucoidan-H and 0.4% of sodium benzoate, stirring until the materials are uniformly mixed, and preparing the moisturizing and repairing essence.

Example 8 preparation of moisturizing repair face essence.

Example 9 preparation of moisturizing repair face essence emulsion.

According to the preparation method, 51.77% of water, 1% of Pellicer L-30, 0.3% of acrylic acid (ester) or C10-30 alkanol acrylate cross-linked polymer and 25% of glycerolyether-26 are added into a water phase pot, stirred until the mixture is completely and uniformly dispersed, then the mixture is added into a main pot, and the temperature is raised and heated to 70-80 ℃. Adding 2% of squalane, 3% of hydrogenated polyisobutene, 3% of shea butter and 4% of glycerol stearate citrate into an oil phase pot, heating and stirring to uniformly mix, and pumping into a main pot under a homogenizing condition; cooling the main pot to below 50 ℃, adding 0.1% dipotassium glycyrrhizinate, 3% nicotinamide, 0.4% tetrahydropyrimidine carboxylic acid, 0.8% DCR516, 5% fucoidan-H, 0.4% phenoxyethanol, 0.08% essence and 0.15% aminomethylpropanol, stirring until the materials are uniformly mixed, and preparing the moisturizing and repairing essence emulsion.

Example 10 preparation of moisturizing repair face essence emulsion.

According to the preparation method, 70.27% of water, 1% of Pellicer L-30, 0.3% of acrylic acid (ester) or C10-30 alkanol acrylate cross-linked polymer and 2% of glycerolyether-26 are added into a water phase pot, stirred until the mixture is completely and uniformly dispersed, then the mixture is added into a main pot, and the temperature is raised and heated to 70-80 ℃. Adding 2% of squalane, 3% of hydrogenated polyisobutene, 3% of shea butter and 2% of glycerol stearate citrate into an oil phase pot, heating and stirring to uniformly mix, and pumping into a main pot under a homogenizing condition; cooling the main pot to below 50 ℃, adding 0.1% dipotassium glycyrrhizinate, 9.5% nicotinamide, 0.4% tetrahydropyrimidine carboxylic acid, 0.8% DCR516, 5% fucoidan-H, 0.4% phenoxyethanol, 0.08% essence and 0.15% aminomethylpropanol, stirring until the materials are uniformly mixed, and completing the preparation of the moisturizing and repairing essence emulsion.

The present application has been described in detail with reference to specific examples, but the embodiments of the present application are not limited to the above embodiments, and those skilled in the art can make various modifications to the present application according to the prior art, which fall within the scope of the present application.

Claims

1. A moisturizing and repairing skin care product is characterized by comprising the following components in percentage by mass,

Pellicer L-30：1％，

DCR516：0.5％，

ink phycocolloid-H: 5 percent,

glycerolyether-26: 5 percent,

dioctyl carbonate: 1 percent,

PEG-40 hydrogenated castor oil: 0.3 percent,

carbomer: 0.3 percent,

nicotinamide: 2 percent,

tetrahydropyrimidine carboxylic acid: 0.3 percent,

phenoxyethanol: 0.4 percent,

essence: 0.05 percent,

aminomethyl propanol: 0.12 percent,

water: the balance.